Clinical trials: Sarcoid
Lung Diseases, Sarcoidosis
Sarcoid Genetic Analysis (SAGA)
To identify sarcoidosis susceptibility genes and to determine how these genes and environmental risk factors interact to cause sarcoidosis.
- Trial name
- NCT00005542
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Lung Cancer (Diagnosis), Sarcoidosis
Immune Cells Role in Lung Cancer and Their Use in Anticancer Immunotherapies and Inflammatory Lung Disease
This study aims to better understand the role of immune system cells in lung diseases such as lung cancer, sarcoidosis, and chronic obstructive pulmonary disease (COPD).
- Conditions
- Lung Cancer (Diagnosis), Sarcoidosis, Chronic Obstructive Pulmonary Disease, Immunotherapy Resistance
- Trial name
- IMMUNOPUMON2 (NCT07384897)
- Testing
- Peripheral Blood Collection for Immune Profiling
- Where
- Belgium
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Sarcoidosis, Tuberculosis
The Serum Angiotensin Converting Enzyme and Lysozyme Levels in Patients Non-infectious and Infectious Uveitis
This study evaluates the significance of differences in serum angiotensin converting enzyme and lysozyme levels of patients with ocular involvement of other autoimmune inflammatory and infectious diseases.
- Trial name
- uveitis (NCT02627209)
- Testing
- spectrophotometric assay, radial immunodiffusion
- Where
- Turkey (Türkiye)
- Volunteers
- 280 people
- Sponsor
- Ozlem Sahin
Sarcoidosis
Diagnostic Usefulness of Fluorine-18-α-Methyltyrosine PET in Combination With 18F-FDG in Sarcoidosis Patient
L-[3-18F]-α-methyltyrosine (FMT) is amino-acid tracer for positron emission tomography (PET), and is used for tumor detection because malignant tumor cells accumulate 18F-FMT based on the increased expression of amino-acid…
- Trial name
- NCT00369980
- Where
- Japan
- Sponsor
- Gunma University
Sarcoidosis
Muscle Strength and Exercise Capacity in Sarcoidosis Patients
The aim of this study is to examine exercise capacity, muscle strength and fatigue in sarcoidosis. In this longitudinal study the changes in prevalence of exercise intolerance, reduced muscle strength and fatigue will be…
- Trial name
- NCT00854672
- Where
- Netherlands
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Muscular Sarcoidosis
Effect of Nelutri™ on Musculoskeletal Biomarkers in Relative Sarcopenia Adults
The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Nelutri™on muscle strength, muscle mass, and muscle function in healthy adults for 12 weeks.
- Trial name
- NCT04320121
- Testing
- Nelutri™
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Sarcoidosis
Testing Hypersensitivity to Metals in Sarcoidosis Patients by Applying the MELISA Test.
The purpose of this study is to apply the MELISA test, that diagnose hypersensitivity to metals, in Sarcoidosis patients with occupational exposure.
- Trial name
- NCT01809145
- Testing
- MELISA test
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cardiac Sarcoidosis
Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression
This is a pilot mechanistic study of the diagnostic utility of sodium-glucose cotransporter-1/2 inhibition (SGLT1/2) on myocardial glucose suppression on FDG PET/CT.
- Trial name
- NCT06510894
- Testing
- Sotagliflozin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tuberculosis, Sarcoidosis
TB and Sarcoidosis Granuloma
Tuberculosis (TB) and sarcoidosis are both granulomatous diseases. Here we compared the immunological micro-environments of granulomas from TB and sarcoidosis patients using in situ sequencing (ISS) transcriptomic analysis and…
- Trial name
- NCT06396910
- Testing
- Spatial transcriptomics
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Uveitis
Uveitis/Intraocular Inflammatory Disease Biobank (iBank)
Background: Uveitis is a serious eye disease that can cause vision loss. Treatment sometimes causes serious side effects or does not work. Researchers want to learn more about uveitis and why some people develop it.
- Trial name
- NCT02656381
- Where
- United States
- Volunteers
- 343 people
- Sponsor
- National Eye Institute (NEI)
Sarcoidosis
Validation of a Non-invasive Diagnostic Method for Sarcoidosis Using Exhaled Breath
Sarcoidosis is a chronic lung disease that is characterized by fatigue, shortness of breath, chest pain and reduced lung function. Suffering from these diseases has a very negative effect on the quality of life.
- Trial name
- NCT02361281
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Sarcoidosis
Registry for Advanced Sarcodiosis
Registry with evaluation and genetic information of patients with advanced sarcoidosis and matched sarcoidosis
- Trial name
- REAS (NCT03769987)
- Testing
- observation
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Cincinnati
Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus
The CARRA Registry
This CARRA Registry study will create a foundational database for rheumatic diseases of childhood using a novel informatics infrastructure developed as part of the larger clinical project.
- Conditions
- Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus, Mixed Connective Tissue Disease, Juvenile Ankylosing Spondylitis
- Trial name
- CARRA Registry (NCT01697254)
- Where
- United States
- Volunteers
- 9,587 people
- Sponsor
- Duke University
Sarcoidosis
Study of Eye Tissue for Sarcoidosis
The purpose of this study is to develop a relatively simple, accurate method of diagnosing sarcoidosis. Sarcoidosis is a disease in which granulomas (nodules of inflamed tissue) develop in various organs, such as the lungs…
- Trial name
- NCT00001278
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Eye Institute (NEI)
Pancreatitis, Chronic, Sarcoidosis
CZI Rare As One: Co-designing an App and Wearable Based Compass for Rare Diseases
The CZI Rare As One study is a Chan Zuckerberg Initiative funded study that aims to co-design and pilot test unique symptom tracking and transmitting apps across 5 different sub-arms that includes individuals with Long COVID…
- Conditions
- Pancreatitis, Chronic, Sarcoidosis, VCP Disease, Long COVID
- Trial name
- NCT06907953
- Testing
- Observational - no intervention
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- 4YouandMe
Lung Diseases, Sarcoidosis
A Case Controlled Etiologic Study of Sarcoidosis (ACCESS)
To test specific hypotheses concerning environmental, occupational, lifestyle, and other risk factors for sarcoidosis. Also, to examine the familial aggregation of sarcoidosis and to test genetic hypotheses concerning its…
- Trial name
- NCT00005276
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sarcoidosis, Tuberculosis
Efficacy of Antituberculous Therapy in Management of Sarcoidosis
From the time sarcoidosis has been described, there has always been a belief that the disease is in some way related to tuberculosis.
- Trial name
- NCT01245036
- Testing
- Antituberculous therapy along with steroids
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Arrhythmogenic Right Ventricular Cardiomyopathy, Cardiomyopathies
Mayo AVC Registry and Biobank
Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic condition which affects the heart and can lead to heart failure and rhythm problems, of which, sudden cardiac arrest or death is the most tragic and dangerous.
- Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy, Cardiomyopathies, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT03049254
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Sarcoidosis
Exercise Training in Sarcoidosis (EXTRAS Study)
Exercise intolerance and reduced health status have been found in patients with sarcoidosis and has been related to skeletal muscle weakness.
- Trial name
- NCT00099424
- Testing
- High-intensity exercise training
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Gasthuisberg
CNS Sarcoidosis
Treatment of CNS Sarcoidosis With H.P. Acthar Gel
The purpose of this study is to see if treatment with H.P. Acthar® Gel will result in the improvement and long-term stabilization of clinical and radiographic abnormalities that occur in patients with CNS sarcoidosis.
- Trial name
- NCT02298491
- Testing
- H.P. Acthar Gel
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Maryland, Baltimore