Clinical trials: Self-Harm
Adolescent Behavior
Brief Intervention for Suicide Risk Reduction in High Risk Adolescents
Adolescent suicide is the 2nd leading cause of death in this age group. There are no validated treatments to decrease the risk of adolescent suicidal behavior, and there are especially no interventions to target the highest risk…
- Trial name
- ASAP (NCT02272179)
- Testing
- As Safe As Possible, Brite, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Pittsburgh
Deliberate Self-Harm
Mentalization-Based Group Therapy for Adolescents
This is a prospective parallel group design of group-based Mentalization-Based Therapy for Adolescents (MBT-A) through a pilot randomised controlled trial comparing group-based MBT-A plus treatment as usual (TAU) to TAU alone.
- Trial name
- NCT02771691
- Testing
- Mentalization-Based Group Therapy for Adolescents
- Where
- United Kingdom
- Volunteers
- 53 people
- Sponsor
- University of Edinburgh
Suicidal Ideation, Suicidal and Self-injurious Behavior
A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum
Rates of suicide have increased significantly over the past two decades, particularly among youth. Compared to the general population, autistic people are significantly more likely to think about suicide, attempt suicide, and die…
- Conditions
- Suicidal Ideation, Suicidal and Self-injurious Behavior, Suicide, Autism Spectrum Disorder
- Trial name
- NCT05398250
- Testing
- Safety Planning Intervention tailored for Autistic Individuals, Safety Planning Intervention Tailored for Autistic Individuals Plus Structured Follow-Up Contacts
- Where
- 5 sites in United States
- Volunteers
- 1,665 people
- Sponsor
- University of North Carolina, Chapel Hill
Suicide, Mental Health Issue
Proximal Risk for Suicide in Adolescents
The central hypothesis is that biometric data can continuously monitor and allow for early identification/intervention of escalating suicidal symptoms.
- Trial name
- NCT06400810
- Testing
- Analog Devices Inc.
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Oregon Health and Science University
Depression, Post Traumatic Stress Disorder
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry
While effective interventions for depression exist, their success rates are unsatisfactory and their provision is haphazard. The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Depression Hub will improve…
- Conditions
- Depression, Post Traumatic Stress Disorder, Bipolar Disorder, Mood Disorder
- Trial name
- NCT02443636
- Where
- Canada
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Suicide, Sexual Violence
Primary Prevention Youth Suicide Trial in Colorado High Schools Prevention Among Colorado High School Students
Sources of Strength is an evidence based program for youth suicide that trains student key leaders to strengthen social connectedness and healthy norms school-wide and is listed on the National Registry of Evidence Based Programs…
- Trial name
- NCT03014271
- Testing
- Sources of Strength (SOS) Prevention Program
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Suicide Prevention
Adapting a Brief Suicide Intervention for Pediatric Primary Care: Enhancing Uptake and Impact
Suicide is a leading cause of death among adolescents in the United States and improving access to high quality just-in-time suicide interventions to reduce risk has important public health implications.
- Trial name
- NCT06499740
- Testing
- Pilot Intervention, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- University of Washington
Suicide Prevention
Practice Facilitation to Enhance Implementation of a Pediatric Suicide Prevention Pathway
Suicide in youth is rapidly growing to where it is the second leading cause of death across the United States. Use of available tools have shown the potential to boost primary care providers' (PCPs) detection of suicide risk and…
- Trial name
- NCT06619782
- Testing
- Practice Facilitation, Training in National Institute of Mental Health Youth Suicide Prevention Pathway
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Colorado, Denver
Suicide
Developing an Intervention to Promote Lethal Means Safety in Suicidal Adolescents
Study Objective: to develop a phone-based intervention to aid parents of suicidal adolescents to adhere to lethal means safety. Lethal means counseling is the practice of educating patients and their families about limiting…
- Trial name
- NCT05423483
- Testing
- Safe Home Text Message Reminders
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hepatic Injury
Attempted Suicide With Acetaminophen Among 8-18 Year-old Children / Adolescents in Denmark
A: Early predictors of hepatic injury after suicide attempt with acetaminophen: To explore the following in a pediatric population with acetaminophen overdose due to suicide attempt: 1) the prevalence of episodes of pre- and…
- Trial name
- NCT01981213
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Hillerod Hospital, Denmark
Psychiatric Disorder
Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in Adolescents
Non-suicidal self-injury (NSSI) are acts defined by the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders 5) as intentional and deliberate, occurring outside a psychotic state and directly causing moderate injury.
- Trial name
- NEUROMUTE (NCT06433583)
- Testing
- transcutaneous auricular vagal nerve stimulation
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Suicidal Ideas, Suicidal Ideation
A Pre-post Study of a Lethal Means Safety Planning Intervention for Youth at Elevated Suicide Risk in the Emergency Department
The purpose of this study is to test whether a lethal means safety planning intervention, TEEN LENS ED, is acceptable to teens at elevated suicide risk and their caregivers in the Emergency Department.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Suicidal Thoughts, Firearm Safety
- Trial name
- TEEN LENS ED (NCT07916792)
- Testing
- TEEN LENS, Usual Care
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Non Suicidal Self Injury, Suicidal Ideation
aiTBS for NSSI and Suicide in Adolescent Depression
Repetitive transcranial magnetic stimulation (rTMS) has been successfully used to help patients with treatment resistant depression.
- Conditions
- Non Suicidal Self Injury, Suicidal Ideation, Suicide and Self-harm
- Trial name
- NCT06210100
- Testing
- Active iTBS
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Central South University
Depression
EEG-Triggered rTMS and Group Therapy for Adolescents With Depression and Self-Harm
This randomized controlled trial aims to evaluate the efficacy of real-time EEG-triggered repetitive transcranial magnetic stimulation (rTMS) combined with group therapy versus rTMS alone in adolescents (aged 12-18 years)…
- Trial name
- NCT07047534
- Testing
- Real-time EEG-triggered Repetitive Transcranial Magnetic Stimulation (rTMS), Group Therapy
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The First Hospital of Hebei Medical University
Suicide Attempt
Treating Suicidality Remotely
Background: Practical and psychological barriers make it difficult for people with Suicidal Thoughts and Behaviors (STBs) to get professional help.
- Trial name
- TREASURE (NCT06370104)
- Testing
- Brief Cognitive Behavioral Therapy for Suicide Prevention, Living under control
- Where
- Netherlands
- Volunteers
- 364 people
- Sponsor
- 113 Suicide Prevention
Suicidal Ideation
Ask Suicide-Screening Questions (ASQ) for Youth With Autism Spectrum and Neurodevelopmental Disorders
Background: Suicide is the second leading cause of death for young people ages 10-24 years. There is no gold standard for evaluating suicidal thoughts and behaviors in young people with autism spectrum disorder (ASD) or other…
- Trial name
- NCT04317118
- Where
- 3 sites in United States
- Volunteers
- 278 people
- Sponsor
- National Institute of Mental Health (NIMH)
Suicide
A Pilot Evaluation of a Digital Peer Support Intervention for Suicidal Adolescents
Suicide risk has increased among youth in underserved communities, where access to mental healthcare is limited. To address this need, the investigator team plans to evaluate the preliminary efficacy of a brief, low-cost…
- Trial name
- SWEEP (NCT06349915)
- Testing
- Supporting Wellbeing with Everyday Experiences of Peers (SWEEP)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Albert Einstein College of Medicine
End of Life
Survey on Palliative Care and Law Perception
The primary objective of the current survey study is to obtain detailed information about European intensive care unit (ICU) clinicians' awareness of palliative care and relevant, local end-of-life (EoL) legislation.
- Trial name
- PCLAW (NCT06245525)
- Testing
- This is not an interventional study
- Where
- Greece
- Volunteers
- 523 people
- Sponsor
- University of Athens
Suicidal Ideation
Validation of the French Version of Ask Suicide-Screening Questions (ASQ) in Adolescents Managed in Pediatric Emergency Unit
The ASQ-Fr study aims at validating the French version of Ask Suicide-Screening Questions composed of 5 items in adolescents managed in pediatric emergency department.
- Trial name
- ASQ-Fr (NCT02900989)
- Testing
- Suicide screening
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Insomnia, Suicidal Ideation
Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior
This study will test the effectiveness of a sleep-related primary suicide prevention program entitled TAILOR (Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior), which includes specific behavior-change…
- Conditions
- Insomnia, Suicidal Ideation, Suicide, Attempted
- Trial name
- TAILOR (NCT05390918)
- Testing
- TAILOR, Enhanced Usual Care
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Jeff Bridge