Clinical trials: Self-harm Behavior
Depressive Symptoms
Efficacity of Psychological Intervention on Reducing the Suicidal Ideations, Depression Level and Improving Reinsertion
Suicide is the third leading cause of death in adolescents and young adults in the United States and the second leading cause in European countries.
- Trial name
- MLADO (NCT03655730)
- Testing
- weekly psychotherapeutic individual sessions, Usual care
- Where
- France
- Volunteers
- 159 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Self Harm
PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm
Approximately 20% of young people experience self-harm behaviour in their lives. Self-harm can occur across different mental health disorders, and lead to negative outcomes and risk of suicide.
- Trial name
- PsiloIMAGINE (NCT06798636)
- Testing
- Psilocybin 5 mg with cognitive behavioural therapy intervention
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Aggression, Self-injurious Behavior
Refinements of Functional Communication Training
Although treatments for problem behavior, like functional communication training (FCT), can be highly effective in the clinic, changes in the way the FCT is implemented (e.g., when transferring treatment to the home, when…
- Trial name
- NCT04045600
- Testing
- Trad FCT, Mult FCT, Mult FCT + Stimulus Fading
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Rutgers, The State University of New Jersey
Suicide, Alcohol Drinking
Brief Alcohol Intervention for Adolescents Who Have Attempted Suicide
The study will use a two group randomized controlled trial to compare a brief motivational interviewing (MI) intervention to TAU with 50 adolescents psychiatrically hospitalized for a suicide plan or attempt who have co-occurring…
- Trial name
- NCT02426957
- Testing
- motivational enhancement therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Bereavement, Depressive Disorder
Consequences of Conjugal Bereavement in Adults
Bereavement refers to the expected reactions and sadness associated with the loss of a loved one. It has been reported that the loss of a spouse is rated as the major life stressor among survivors of varying ages and diverse…
- Conditions
- Bereavement, Depressive Disorder, Immunologic Disease, Mental Disorder
- Trial name
- NCT00001659
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Self-harm, Emotion Regulation
Feasibility of Emotion Regulation Group Therapy for Adolescent Self-Harm
Deliberate self-harm (DSH) is a prevalent behaviour among adolescents but there is no current recommendation for an efficacious treatment.
- Conditions
- Self-harm, Emotion Regulation, Adolescent - Emotional Problem
- Trial name
- ERGT-A (NCT06297824)
- Testing
- ERGT-A
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Karolinska Institutet
Suicide Attempt, Suicidal Ideation
Bae: A Smartphone Application for a Better Following Adolescents at Risk of Suicidal Behavior: Study of Acceptability and Preliminary Results of Efficacy
Suicidal behavior among adolescents is a major public health problem. Exacerbation of suicidal risk most often occurs when the young person is in his or her natural environment, far from the health care system.
- Trial name
- BAE (NCT04686162)
- Testing
- bae application
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Suicidal Ideation, Depression
Implementing an IPTS Treatment Approach to Improve Outcomes in Suicidal Youth
The purpose of this project is to evaluate a set of interventions derived from a theory of suicide that supplements a clinical program and compare their effects on outcomes to the outcomes of the unsupplemented program.
- Trial name
- NCT03527459
- Testing
- SPARC B, SPARC A
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- University of Texas Southwestern Medical Center
Non-suicidal Self-injury (NSSI)
Efficacy of Triple-daily 15mA tACS on Adolescent NSSI
This study aims to evaluate the clinical effectiveness of triple-daily 15 mA tACS stimulation in adolescents with Nonsuicidal Self-Injury (NSSI) by comparing the outcomes of active versus sham tACS interventions.
- Trial name
- NCT06919432
- Testing
- Active-tACS (Nexalin Technology, Inc., Houston, TX, USA)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Mental Health Center
Self-Injurious Behavior
Imaginator: a Pilot of Brief Functional Imagery Training for Self-harm
Self-harm has substantial personal impacts as well as costs on the National Health Service (NHS). Around 13-17% of young people report experiences of self-harm.
- Trial name
- Imaginator (NCT02914847)
- Testing
- Functional Imagery Training (FIT)
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical Research Council
Suicidal Ideation
Dynamic Deconstructive Psychotherapy Versus Brief Intervention and Contact for Suicidal Adolescents and Young Adults
The purpose of this clinical trial is to assess whether 6 months of treatment with Dynamic Deconstructive Psychotherapy (DDP) is more effective for reducing thoughts of suicide in suicidal adolescents and young adults than usual…
- Trial name
- NCT05988489
- Testing
- Dynamic Deconstructive Psychotherapy (DDP), Brief Intervention and Contact (BIC)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- State University of New York - Upstate Medical University
Autism Spectrum Disorder
A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder
The purpose of this study is to demonstrate the feasibility of a 9-week, randomized trial of N-acetylcysteine (NAC) compared to placebo in 14 children (age 5 to 12 years) with Autism Spectrum Disorder (ASD) and a moderate level…
- Trial name
- NAC (NCT03008889)
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Emory University
Distress; Maternal, Self-Efficacy
Integrated Intervention for Caregivers--Open Trial
Adolescents who have been hospitalized for suicidal behavior are at risk for engaging in additional suicidal behavior. After hospitalization, parents or guardians are typically asked to be responsible for helping to prevent…
- Conditions
- Distress; Maternal, Self-Efficacy, Parenting, Suicide
- Trial name
- NCT03487575
- Testing
- Open trial
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wake Forest University Health Sciences
Intentional Self Harm
Long Term Efficacy of DBT-A in Adolescents With Repetitive Self-harming and Suicidal Behaviours
The purpose of the study is to evaluate the long-term efficacy of dialectical behavior therapy (DBT) in treatment of adolescents with deliberate self harm compared to enhanced usual care (EUC).
- Trial name
- NCT01593202
- Testing
- Dialectical behavior therapy, Enhanced usual care
- Where
- Norway
- Volunteers
- 77 people
- Sponsor
- Oslo University Hospital
Suicide
STAT-ED: Suicidal Teens Accessing Treatment After an Emergency Department Visit
This study looks to implement a novel intervention (STAT-ED) for children who screen positive to suicide ideation. The intervention looks to collect data from several different measures and then randomize participants into one of…
- Trial name
- STAT-ED (NCT01779414)
- Testing
- STAT-ED Intervention
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Suicidal Ideation, Self-Injurious Behavior
Youth Suicide and Self-Harm Intervention: Clinical and Biological Outcomes Study
The goal of this clinical trial is to develop and evaluate youth-focused intervention programs for suicide and self-harm that are tailored to the psychological, developmental, and cultural characteristics of Korean adolescents…
- Conditions
- Suicidal Ideation, Self-Injurious Behavior, Suicide, Attempted
- Trial name
- SHIELD (NCT07395752)
- Testing
- Self-Harm Intervention and Education for Long-term Development (SHIELD) Program, General Mental Health Education
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ajou University School of Medicine
Anxiety Disorders, Depression
Pharmacogenomics of Antidepressant Response in Children and Adolescents
This study will identify variations in genes that may be involved in the development of suicidal events or certain behaviors in youth who are exposed to antidepressant medications.
- Conditions
- Anxiety Disorders, Depression, Eating Disorders, Obsessive-Compulsive Disorder
- Trial name
- PARCA (NCT00516932)
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Duke University
Adolescents, Mental Disorder Diagnosed in Childhood
Detecting Risk of Suicide in a Pediatric Emergency Department
Objective: The ultimate goal of this project is to enhance the capacity of non-mental health clinicians working in an Emergency Departments (ED) to recognize and initiate further evaluation of children and adolescents at risk for…
- Conditions
- Adolescents, Mental Disorder Diagnosed in Childhood, Suicide Prevention
- Trial name
- NCT00623493
- Where
- 3 sites in United States
- Volunteers
- 524 people
- Sponsor
- National Institute of Mental Health (NIMH)
Mental Health Disorder, Suicide Attempt
Efficacy of the I-CARE Digital Health Intervention
When presenting to an ED with suicide, self-harm or other mental health crises, youth may also experience "boarding", which is defined by the Joint Commission as "the practice of holding patients in the ED or another temporary…
- Conditions
- Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
- Trial name
- NCT07150832
- Testing
- Improving Care, Accelerating Recovery & Education (ICARE)
- Where
- 4 sites in United States
- Volunteers
- 173 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Suicide Jumps, Psychiatry
The "Suicide Guard Rail": A Structural Intervention for Hospitals Avoid Suicides by Jumping From Heights Buildings
Background: Suicides by jumping from the high buildings of acute hospitals are dramatic events which are highly traumatizing to families, staff and fellow pts.
- Trial name
- NCT02889731
- Volunteers
- 10 people
- Sponsor
- Kantonsspital Baden