Clinical trials: Sentinel Lymph Node
Cervical Cancer
Analysis of Parametrial Lymph Nodes as Sentinel Nodes in Patients With Cervical Cancer
The goal of this clinical research study is to find out if the parametrial nodes are "sentinel" nodes (the lymph nodes believed to be the greatest risk for the spread of cancer) and if intraoperative lymphatic mapping can…
- Trial name
- NCT00631241
- Testing
- Single Photon Emission Computed Tomography, Intraoperative Lymphatic Mapping
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer Invasive
Intra-operative Detection of Positive Margins and Lymph Nodes in Breast Surgery
In this project, the investigators will develop novel optical coherence tomography (OCT)-Raman spectroscopy and autofluorescence (AF)-Raman spectroscopy systems based on a selective sampling approach optimised for high-resolution…
- Trial name
- NCT06977698
- Testing
- OCT-Raman, AF-Raman
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Gynecological Surgeries
A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries(SPiM-RWS-GYN)
Study name：A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries Study purpose：This clinical trial is a real-world study to evaluate the clinical…
- Trial name
- NCT06082011
- Testing
- da Vinci SP Surgical System
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Ruijin Hospital
Sentinel Lymph Node, Breast Cancer
Application of Surgical Navigation System in Sentinel Lymph Node of Breast Cancer Research
The purpose of this study is to compare the sentinel lymph node (SLN) detection rate of early breast cancer patients between using Indocyanine green (ICG) and Methylene blue with a novel surgical navigation system.
- Trial name
- NCT02084784
- Testing
- Indocyanine green, methylene blue
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Chinese Academy of Sciences
Early Gastric Cancer
Laparoscopic-endoscopic Surgery Assisted Sentinel Lymph Node Navigation Surgery for Early Gastric Cancer
This study is to evaluate the safety and efficacy of dual-endoscope assisted sentinel lymph node navigation surgery for early gastric cancer (EGC).
- Trial name
- NCT07615374
- Testing
- Laparoscopic-endoscopic cooperative surgery (LECS) Assisted Sentinel Lymph Node Navigation Surgery
- Where
- 2 sites in China
- Volunteers
- 36 people
- Sponsor
- Jilin University
Gastric Cancer, Sentinel Lymph Node
Gastric Cancer Sentinel Lymph Node Mapping
Gastric cancer has an incidence in North America of over 24,000 new cases annually, of which approximately 15% are diagnosed at an early stage.
- Conditions
- Gastric Cancer, Sentinel Lymph Node, Early Gastric Cancer
- Trial name
- NCT03049345
- Testing
- Sentinel Lymph Node Sampling, Radioactive Tracers, Methylene Blue 20 MG/ML
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Breast Cancer
Preoperative Localisation of the Sentinel Lymph Node in Breast Cancer
When a person has breast cancer it is necessary to find out whether the cancer has spread to the lymph nodes in the armpit because if it has, further treatment is likely to be needed.
- Trial name
- NCT01154972
- Testing
- Preoperative sentinel lymph node identification and marking
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- NHS Tayside
Colonic Neoplasms
Swiss Prospective, Multicenter Study Sentinel Lymph Node Procedure in Colon Cancer
The study is a feasibility and validation study of the sentinel lymph node (SLN) procedure in all stages of colon cancer. If the SLN can be reliably identified, it could be submitted to a more accurate histopathological…
- Trial name
- NCT00826579
- Testing
- Sentinel lymph node procedure, Bone marrow aspiration
- Where
- 3 sites in Switzerland
- Volunteers
- 192 people
- Sponsor
- University Hospital, Basel, Switzerland
Breast Cancer
The Accuracy of Sentinel Node Biopsy of Breast Cancer With Sonographic Abnormal Axillary Lymph Nodes
This is a phase II, prospective, single-center, non-randomized, non-controlled study. Sentinel lymph node biopsy (SNB) is a standard staging procedure in early breast cancer.
- Trial name
- NCT02005926
- Testing
- Wire-localized abnormal node
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tao OUYANG
Gastric Cancer, Sentinel Lymph Node
Fluorescence Image-Guided Lymphadenectomy in Robotic Gastrectomy
Gastric cancer is a worldwide challenge due to its spread, even epidemic in some areas, and the high mortality rates. Lymphadenectomy is considered the fundamental step during radical gastrectomy.
- Trial name
- IG-MIG (NCT03931044)
- Testing
- Image-Guided Robotic Gastrectomy
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- International Study Group on Minimally Invasive Surgery for Gastric Cancer
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
Lymph Node Mapping and Sentinel Lymph Node Identification in Patients With Stage IB1 Cervical Cancer
This clinical trial is studying how well lymph node mapping and sentinel lymph node identification work in finding lymph node metastases in patients with stage IB1 cervical cancer.
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Stage I Cervical Cancer
- Trial name
- NCT00070317
- Testing
- Isosulfan Blue, Lymph Node Mapping, Lymphangiography
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Gynecologic Oncology Group
Breast Cancer, Sentinel Lymph Node
Sentinel Lymph Node Biopsy in Early Breast Cancer: a Real-world Multicenter Cross-sectional Study (CABS001 Study)
Objective: To investigate the current clinical practice of sentinel lymph node biopsy (SLNB) in patients with early stage breast cancer in China.
- Trial name
- NCT04156841
- Testing
- mapping agent, neoadjuvant chemotherapy
- Where
- China
- Volunteers
- 21,000 people
- Sponsor
- Xijing Hospital
Cancer of Endometrium
Use of the Sentinel Node Biopsy for Early Endometrial Cancer.
This is an obstervationnal study, to evaluate the good clinical practice of the use of the sentinel node biospy in early stage endometrial cancer.
- Trial name
- SNE (NCT02545348)
- Testing
- Sentinel Lymph Node Biopsy
- Where
- 10 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Breast Cancer
Sentinel Lymph Node Total Tumoral Load as a Predictor of Non Sentinel Node Involvement in Early Breast Cancer
This is a retrospective, multicentric cohort study of patient cases with cT1-3, N0 early breast cancer, who previously had intraoperative sentinel lymph node (SLN) evaluation by one-step nucleic acid amplification (OSNA) assay…
- Trial name
- SOLO-1 (NCT01669265)
- Where
- 9 sites in Spain
- Volunteers
- 701 people
- Sponsor
- SOLTI Breast Cancer Research Group
Thyroid Cancer, Lymph Node Metastasis
The Usefulness of Staining Lymph Nodes During Operations for Cancer Thyroid in Detecting the Nodes That Have Cancer
Detection of lymph nodes starting to be involved by cancer spreading from the thyroid gland during operation is useful. It saves the patient from having a second operation to remove these nodes later on when they become obvious.
- Trial name
- NCT00794053
- Testing
- detecting lymph node metastasis by staining
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- University of Alexandria
Breast Cancer
Injection Methods in Finding the Sentinel Lymph Node During Lymphatic Mapping and Sentinel Lymph Node Biopsy in Patients With Invasive Breast Cancer
RATIONALE: Diagnostic procedures, such as lymphoscintigraphy using an injection under the nipple or near the tumor, may help doctors find out how far the disease has spread.
- Trial name
- NCT00438477
- Testing
- Isosulfan Blue, Lymphangiography, Technetium Tc 99m sulfur colloid
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- M.D. Anderson Cancer Center
Vaginal Cancer
Lymphoscintigraphy in Patients With Vaginal Cancer
Primary Objectives: 1. Determine the feasibility of using pretreatment lymphoscintigraphy to identify the sentinel lymph node(s) in patients with vaginal cancer dispositioned to receive radiation therapy. 2.
- Trial name
- NCT00528034
- Testing
- Lymphoscintigraphy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- M.D. Anderson Cancer Center
Recurrence, Breast Cancer
Sentinel Node Biopsy in Breast Cancer Patients
Axillary lymph node dissection (ALND) was previously the standard axillary staging procedure in breast cancer patients. However, ALND is accompanied by a considerable morbidity, and sentinel lymph node biopsy (SLNB) evolved as a…
- Trial name
- NCT01351974
- Where
- Sweden
- Volunteers
- 3,369 people
- Sponsor
- Uppsala University
Breast Neoplasm
Complications After Lumpectomy, Sentinel Node and Radiotherapy in Breast Cancer Patients and Physiotherapy Care
To make an inventory of the physiotherapeutic care and the post-operative complications of patients who have undergone lumpectomy, sentinel node and radiotherapy treatment.
- Trial name
- COTUKI (NCT04444882)
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Grenoble
Porocarcinoma, Sentinel Lymph Node
Sentinel Lymph Node Biopsy in Porocarcinoma
Eccrine porocarcinoma (EPC) is a slow-growing carcinoma arising from the eccrine sweat glands. Based on its clinical presentation it can be confused with malignant and benign skin lesions, both.
- Trial name
- NCT03647631
- Testing
- sentinel lymph node biopsy
- Where
- Italy
- Volunteers
- 2 people
- Sponsor
- Ospedale Policlinico San Martino