Clinical trials: Severely Burned Patients
Burn Scar
Microneedling for Burn Hypertrophic Scars
Approximately 33 to 91% of severe burn victims will develop hypertrophic scars. Hypertrophic scars are defined as erythematous (red), raised and rigid scars that can cause pain and itching, among other things.
- Trial name
- NCT05423613
- Testing
- Microneedling
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Burns
Assessment of Mechanisms of Improved Wound Healing
The purpose of this study is to find ways to improve wound healing and decrease the negative effects of trauma from burn injury.
- Trial name
- NCT00673309
- Testing
- Stable Isotope Infusion study, Insulin High Dose, oxandrolone
- Where
- United States
- Volunteers
- 644 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Peer Bullying Intervention, Vodcast
Early Detection and Kinetics of Sepsis-Induced Coagulopathy in Severe Burn Patients
The purpose of this study is to evaluate the impact of an avatar-supported, teacher-student interactive, vodcast-based peer bullying prevention program-developed for adolescents-on students' ability to identify peer bullying…
- Conditions
- Peer Bullying Intervention, Vodcast, Students
- Trial name
- SIC-BURN-JAAM2 (NCT07905807)
- Testing
- Vodcast-Based Peer Bullying Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Infections on, Severe Burn Patients
Effect of Early Enteral Tube Feeding Nutrition With an Immune Enhancing Diet in Severe Burn Patients
Compare clinical and biological effects of two enteral tube feeding nutrition formula (immune enhancing diet versus polymeric diet)in severe burn hospitalized patients .
- Trial name
- NCT00561210
- Testing
- Crucial, Sondalis HP
- Where
- 5 sites in France
- Volunteers
- 57 people
- Sponsor
- Société des Produits Nestlé (SPN)
Burns, Liver Fibroses
Liver, Pancreas and Thyroid Function in Burn Patients
The purpose of this study is to determine the extent to which severe burn injuries affect the morphology and function of liver, pancreas and thyroid.
- Conditions
- Burns, Liver Fibroses, Pancreas Disease, Thyroid Diseases
- Trial name
- NCT03598283
- Testing
- Ultrasound/transient elastography
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Air or Gas Embolism, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Registry
The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of…
- Conditions
- Air or Gas Embolism, Carbon Monoxide Poisoning, Clostridial Myositis and Myonecrosis (Gas Gangrene), Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias
- Trial name
- HBOTR (NCT02483650)
- Volunteers
- 5,000 people
- Sponsor
- U.S. Wound Registry
Burns
Determination of Nerve Growth Factor (NGF) Expression in Pediatric Patients With Severe Burns: a Pilot Study
The goal of this observational study is to determine the blood values of NGF in severely burned patients, to describe any changes over time and finally to correlate the expression of NGF to the severity of the burn.
- Trial name
- NCT05751174
- Testing
- pediatric patients affected by severe burns
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Burns
Organ Protective Effect of Cetirizine In Patients With Severe Burns
This prospective clinical trial aims to investigate the organ protective effects of cetirizine in patients with severe burns.
- Trial name
- NCT06126991
- Testing
- Cetirizine, Midazolam and Fentanyl
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Ruijin Hospital
Burn Degree Second, Burn Degree Third
The Use of Cultured (Dermal) Epithelial Autografts in Severely Burned Patients
The Swisskera project is a multicenter follow-up study at the three Swiss burn centers evaluating long-term outcomes after burn wound coverage with lab-grown epithelial grafts, specifically cultured epithelial autograft (CEA)…
- Conditions
- Burn Degree Second, Burn Degree Third, Skin Transplantation, Full Thickness Skin Defects
- Trial name
- Swisskera (NCT07415577)
- Testing
- Standard of Care (SOC)
- Where
- 3 sites in Switzerland
- Volunteers
- 236 people
- Sponsor
- University Children's Hospital, Zurich
Burns
Antimicrobial Resistance of Bacteria in Burn Patients
The purpose of this study is to test the resistance of pathogenic bacteria in infected tissues of burn patients to various antimicrobials and enzyme debriders.
- Trial name
- NCT00794742
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Texas Tech University Health Sciences Center
Burns, Burn Injury
Predictive Role of Glucose/Potassium Ratio on Mortality in Major Burns.
The aim of this observational study is to investigate the role of the glucose-potassium ratio in predicting mortality in patients with major burn trauma.
- Conditions
- Burns, Burn Injury, Inhalation Injury
- Trial name
- NCT06561282
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Konya Meram State Hospital
Second or Third Degree Burns
Acute and Long-Term Outcome Investigations of Fenofibrate on Severely Burned Patients
The purpose of this study is to learn the following: whether long-term treatment (6 months) with fenofibrate will decrease burn related sugar and fat increased in the blood and help prevent muscle loss and improve wound healing.
- Trial name
- NCT01574131
- Testing
- Fenofibrate, Sugar Pill
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burn Injury
Amino Acid Supplementation in Recovery From Severe Burns
Exercise during recovery is now Standard of Care at Shriners Hospital for Children Galveston, since positive effects of exercise training were found on lean body mass and recovery after burns.
- Trial name
- ExAA (NCT01618630)
- Testing
- EAA Supplementation + Exercise Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Ocular Burns
Corneal Epithelial Autograft With Middle Lamellar Keratoplasty for Severe Ocular Burns
The purpose of this pilot study is to explore whether corneal epithelial autograft (EA) combined with allogeneic middle lamellar keratoplasty (AMLK) is more effective than limbal autograft (LA) with AMLK for ocular surface…
- Trial name
- NCT03421769
- Testing
- EA and AMLK, LA and AMLK
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Yingfeng Zheng
Burn Injury
Effect of n-3 PUFA From Fish in Enteral Nutrition of Major Burn Patients
Studies have shown that burn patients may benefit from low fat diets, but there is still no strong data regarding the impact of fatty acid composition used for feeding.
- Trial name
- OmegaBurn (NCT02189538)
- Testing
- ω-3 PUFA, Low fat enteral diet
- Where
- Uruguay
- Volunteers
- 100 people
- Sponsor
- Centro Nacional de Quemados, Uruguay
Burns
Effect of Music Therapy on Families of Burn Patients
The purpose of this study is to investigate the efficacy of music therapy in assisting with the coping and adjustment of children of adults with major burns.
- Trial name
- MTS3 (NCT00824681)
- Testing
- Sound Of Family Together (S.O.F.T.) Music Program, Non-Therapy Related Activities (NTRA)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- MetroHealth Medical Center