Clinical trials: Sex
mHealth, PMTCT
Mobile Strategies for Women's and Children's Health: Optimizing Adherence and Efficacy of PMTCT/ART
The investigators are conducting a 3-arm randomized trial comparing the effects of unidirectional SMS (ie: "push" messaging to participant) vs. bidirectional SMS dialogue between participant and provider vs.
- Conditions
- mHealth, PMTCT, Adherence, Medication, SMS
- Trial name
- Mobile WAChx (NCT02400671)
- Testing
- SMS messaging
- Where
- 6 sites in Kenya
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- University of Washington
ADHD, Attention Deficit Hyperactivity Disorder
Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD
The purpose of the study is to examine the developmental trajectory of response control in boys and girls with ADHD entering adolescence.
- Trial name
- NCT05927506
- Testing
- Other
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
HIV Infections
The Safety of Zidovudine Plus Interferon-Alpha in HIV-Infected Children
PRIMARY: To determine the maximum tolerated dose of interferon-alfa (IFN-A) alone and in combination with zidovudine (AZT); to assess the safety and tolerance of IFN-A alone and in combination with AZT.
- Trial name
- NCT00000967
- Testing
- Interferon alfa-2a, Zidovudine
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 52 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cyberbullying
Bullying Prevention Intervention for Adolescent Primary Care Patients
The purpose of this randomized controlled study is to evaluate acceptability and feasibility, and to gather preliminary data about efficacy, of "iPACT" (intervention to Prevent Adolescent Cyber-victimization with Text messages)…
- Trial name
- iPACT (NCT03467009)
- Testing
- iPACT Intervention, Control: Enhanced Usual Care (EUC), iPACT Intervention- app
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Rhode Island Hospital
Sexual Dysfunction
Motivational Interviews With Women Experiencing Sexual Dysfunction During Menopause Period
The aim of this study is to evaluate the effect of motivational interviews with women who experience sexual dysfunction during menopause on sexual quality of life and self-efficacy.The population of the study consisted of…
- Trial name
- NCT06337058
- Testing
- Experimental group (motivational interview)
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Hülya KAMALAK
Autistic Disorders Spectrum, Sexual Behavior
Sexaffectivity in Autistic Spectrum Disorder
The WHO defines sexual health as a state of physical, emotional, mental and social well-being, related to sexuality, not only the absence of illness, dysfunction or disability.
- Conditions
- Autistic Disorders Spectrum, Sexual Behavior, Adolescent Development, Sexual Inadequacy
- Trial name
- NCT03625609
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Parc Taulí Hospital Universitari
Gonorrhea Female, Chlamydia Females
The Integrated Female Sexually Transmitted Infection Testing for HIV Epidemic Control Through PrEP (IN-STEP) Study
Globally, new HIV infections are concentrated in eastern and southern Africa where the infections are largely acquired by women outside of known key populations.
- Conditions
- Gonorrhea Female, Chlamydia Females, Syphilis Female, Trichomonas Vaginalis
- Trial name
- IN-STEP (NCT06743204)
- Testing
- Self-Reported Risk Screening for PrEP and Diagnostic STI testing, Self-reported risk screening for PrEP and syndromic management for STIs
- Where
- Uganda
- Volunteers
- 5,560 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cryptosporidiosis, HIV Infections
A 28-Day Study of Diclazuril in the Treatment of Cryptosporidiosis in Patients With AIDS
To evaluate the safety and efficacy of diclazuril capsules as a treatment for cryptosporidial related diarrhea in AIDS patients who have been treated in the double-blind study # JRD 64,433/1101 and have relapsed, or de-novo…
- Trial name
- NCT00002278
- Testing
- Diclazuril
- Where
- 3 sites in United States
- Sponsor
- Janssen, LP
Mycobacterium Avium-intracellulare Infection, HIV Infections
The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS
To evaluate three doses of clarithromycin in children with AIDS and Mycobacterium avium complex (MAC) infection who are receiving concurrent antiretroviral therapy.
- Trial name
- NCT00000971
- Testing
- Clarithromycin, Zidovudine, Didanosine
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Abbott
Sexual Behavior, Depression
Our Family Our Future: Acceptability and Feasibility Study of a Family Prevention Program for HIV Risk and Depression
The purpose of this study is to assess the feasibility and acceptability of a family-based preventive intervention designed to reduce sexual risk behaviors and depressive symptoms among South African adolescents and their…
- Trial name
- NCT02432352
- Testing
- Our Family Our Future
- Where
- South Africa
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Brown University
Fragile x Syndrome
Ganaxolone Treatment in Children With Fragile X Syndrome
This Phase 2 proof-of-concept study is a double-blind, randomized, placebo-controlled, crossover study to investigate ganaxolone treatment in children with fragile x syndrome (FXS).
- Trial name
- NCT01725152
- Testing
- Ganaxolone
- Where
- 2 sites in United States, Belgium
- Volunteers
- 59 people
- Sponsor
- Marinus Pharmaceuticals
Acne Vulgaris
The Effects of Systemic Isotretinoin Treatment on Adrenal Steroid and Sex Hormones Level in Severe Acne Vulgaris
Acne vulgaris is a chronic inflammatory skin disease involving the pilosebaceous unit, affecting approximately 95% of adolescents and young adults.
- Trial name
- NCT05903716
- Testing
- Hormone, Isotretinoin
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
HIV Infections
Pediatric Expanded Access Program-Oral Solution (0831-908)
Monitor the safety and tolerability of efavirenz oral solution in combination with Antiretroviral Therapy for the treatment of patients age 3 to 16 years who have failed therapy or who are intolerant to their current therapy.
- Trial name
- NCT00543530
- Testing
- MK0831
- Sponsor
- Merck Sharp & Dohme LLC
HIV Infections
Pharmacokinetics and Safety Study of Tipranavir in Combination With Low Dose Ritonavir in Human Immunodeficiency Virus (HIV)-Infected Children
The primary objective of this study is to assess the safety and tolerability of tipranavir (TPV) oral formulation and soft gelatin capsules together with low-dose ritonavir in HIV-infected children and adolescents, to provide…
- Trial name
- NCT00076999
- Testing
- TPV oral solution, RTV oral solution
- Where
- 30 sites in United States, Argentina and 8 more
- Volunteers
- 115 people
- Sponsor
- Boehringer Ingelheim
WAGR Syndrome, Wilm's Tumor
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions
This study will explore conditions caused by the absence of certain genes on chromosome 11. These conditions include WAGR syndrome, which is characterized by a kidney tumor called Wilm s tumor, aniridia (absence of the iris of…
- Conditions
- WAGR Syndrome, Wilm's Tumor, Aniridia, Urogenital Abnormalities
- Trial name
- NCT00758108
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV
PHAT Life: Preventing HIV/AIDS Among Teens in Juvenile Justice
PHAT Life: Preventing HIV/AIDS Among Teens, is a uniquely-tailored intervention designed for recently-arrested juvenile offenders on probation.
- Trial name
- PHAT Life (NCT02647710)
- Testing
- PHAT Life Intervention, Health Promotion Control
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
HIV/AIDS
Pediatric Decentralization of ART in South Africa
The decentralization study will describe children taking antiretroviral therapy (ART) at a larger health facility in the Eastern Cape province of South Africa, between the years of 2004-2013.
- Trial name
- NCT03049891
- Testing
- Data abstraction, Tracing questionnaire, Tier.net
- Where
- 15 sites in South Africa
- Volunteers
- 1,583 people
- Sponsor
- Columbia University
Hiv, AIDS
ALHIV Smartphone Game Study
This is a cluster-randomized controlled trial that aims to conduct comprehensive feasibility testing of a smartphone game in a sample of 120 adolescents living with HIV (ALHIV) ages 15-21 in Kisumu, Kenya, to determine whether…
- Conditions
- Hiv, AIDS, Adolescent Behavior, Treatment Compliance
- Trial name
- NCT06913660
- Testing
- MyGoals, Standard of care
- Where
- Kenya
- Volunteers
- 120 people
- Sponsor
- Emory University
HIV
Likely Use of PrEP for African American YMSM
HIV Pre-Exposure Prophylaxis (PrEP), in the form of the anti-retroviral pill Truvada©, has been approved by the FDA as a method for reducing HIV transmission rates in the population, particularly young men who have sex with men…
- Trial name
- NCT02810249
- Testing
- No intervention used
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
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