Clinical trials: Skin Condition
Chorioamnionitis, Pregnancy Complications, Infectious
Closure of Skin in ChorioAmnionitis Research Pilot Study
The purpose of the CSCAR pilot study is to improve the design of a full-scale trial by determining the patient recruitment rate and participation rate.
- Conditions
- Chorioamnionitis, Pregnancy Complications, Infectious, Complications; Cesarean Section, Postoperative Complications
- Trial name
- CSCAR (NCT01988168)
- Testing
- Suture closure, Staples closure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Fatty Liver Disease, Nonalcoholic, Nonalcoholic Steatohepatitis
Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) Associated With Lipodystrophy
This study involves research about an investigational medicine called metreleptin. The reason for this study is to find out how metreleptin can improve non-alcoholic steatohepatitis or nonalcoholic fatty liver disease associated…
- Conditions
- Fatty Liver Disease, Nonalcoholic, Nonalcoholic Steatohepatitis, Lipodystrophy
- Trial name
- NCT01679197
- Testing
- Metreleptin
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan
Nail Diseases
Subclinical Nail Involvement in Relevant Skin Diseases
Onychopathies constitute one of the major challenges faced by a dermatologist in terms of its early detection and diagnosis . Many disorders can affect the nails, including deformity and dystrophy, infections, and ingrown…
- Trial name
- NCT04092413
- Testing
- Dermoscope
- Volunteers
- 384 people
- Sponsor
- Assiut University
Onychomycosis
A Vehicle-controlled Study of Topical MOB015B in the Treatment of Distal Subungual Onychomycosis (DSO)
This is a Phase 3 multicenter, double-blind study to evaluate the safety and efficacy of vehicle-controlled topical MOB015B in the treatment of Distal Subungual Onychomycosis (DSO)
- Trial name
- NCT05279846
- Testing
- MOB015B
- Where
- 35 sites in United States, Canada
- Volunteers
- 350 people
- Sponsor
- Moberg Pharma AB
Leg Ulcers, Varicose Ulcers
Legtest Multi Centre Testing of the Lively Legs Program for Promoting Compliance in Leg Ulcer Patients
Leg ulcers are often chronic or recurring complications of peripheral circulation disorders. Patients' lifestyles are known to influence leg ulcer occurrence and circulation disorders in general.
- Trial name
- NCT00184873
- Testing
- Health Counseling
- Where
- 11 sites in Netherlands
- Volunteers
- 180 people
- Sponsor
- Radboud University Medical Center
Breast Cancer
Long-Term Effect of Adolescent Diet on Hormones and Breast Cancer Risk in Women Previously Enrolled in the Dietary Intervention Study in Children
RATIONALE: The amount and type of fat in the diet may affect hormone levels, bone mineral density, and breast density later in life. This may affect the risk of developing breast cancer.
- Trial name
- NCT00458588
- Testing
- physiologic testing, questionnaire administration, breast imaging study
- Where
- 10 sites in United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Breast Cancer
Study of Biomarkers in Tissue Samples From Patients With Breast Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01004796
- Testing
- cytogenetic analysis, microarray analysis, mutation analysis
- Sponsor
- University of Wisconsin, Madison
Rheumatoid Arthritis (RA
Effects of Chronic Non-invasive Vagus Nerve Stimulation in an Asplenic Individual Suffering From Rheumatoid Arthritis
The goal of this clinical trial is to learn if chronic self-administrated non-invasive vagus nerve stimulation works to improves the disease activity in a single asplenic patient suffering from rheumatoid arthritis.
- Trial name
- NCT07646470
- Testing
- Trans-auricular vagus nerve stimulation
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Osteoflow Health Clinic
Kidney Diseases, Lupus Nephritis
Prospective, Randomized, Multicenter, Control Study to Assess the Efficacy and Safety of Tacrolimus in Induction and Maintenance Phase Treatment in Lupus Nephritis
The purpose of this study is to compare the efficacy and safety of tacrolimus vs intravenous cyclophosphamide pulses treatment for the induction therapy of LN(III,IV,V).
- Conditions
- Kidney Diseases, Lupus Nephritis, Tacrolimus, Induction Phase
- Trial name
- NCT00615173
- Testing
- tacrolimus (FK506), cyclophosphamide or azathioprine
- Where
- China
- Volunteers
- 81 people
- Sponsor
- Sun Yat-sen University
Porphyria Cutanea Tarda
Study of the Pathogenesis of Porphyria Cutanea Tarda
OBJECTIVES: I. Determine the effect of standard treatments on various predisposing factors in patients with porphyria cutanea tarda (PCT). II.
- Trial name
- NCT00005103
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Center for Research Resources (NCRR)
Atopic Dermatitis
Scratch Behavior Under Standard of Care
Wrist-worn accelerometers and associated data analysis platforms will provide quantitative and qualitative knowledge regarding the action of scratching and sleep quantity in a symptomatic Atopic Dermatitis (AD) population.
- Trial name
- SOC (NCT03898427)
- Testing
- Wrist Actigraphy Devices, Polysomnography, Videography
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston University
Crohn Disease
Topical Tacrolimus 0.1% Ointment For Treatment Of Cutaneous Crohn's Disease
An assessment of the efficacy of topical tacrolimus in the treatment of cutaneous crohns disease
- Trial name
- NCT01233570
- Testing
- Tacrolimus
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Aberdeen
Mucopolysaccharidosis VI (MPS VI, Maroteaux-Lamy Syndrome)
Mucopolysaccharidosis (MPS) VI Clinical Surveillance Program (CSP)
The objectives of this program are: to further characterize the natural progression of MPS VI disease; to generate and disseminate information on the care and management of MPS VI patients to clinical and medical professionals…
- Trial name
- NCT00214773
- Where
- 50 sites in United States, Australia and 11 more
- Volunteers
- 237 people
- Sponsor
- BioMarin Pharmaceutical
Still's Disease, Juvenile Onset, Still's Disease, Adult-Onset
A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD)
A study to demonstrate efficacy and safety of anakinra in pediatric and adult Japanese patients with Still's disease (Systemic juvenile idiopathic arthritis [SJIA] and Adult-onset Still's disease [AOSD]).
- Trial name
- NCT05814159
- Testing
- Anakinra
- Where
- 8 sites in Japan
- Volunteers
- 15 people
- Sponsor
- Swedish Orphan Biovitrum
Cervical Cancer, Human Papillomavirus Infection
Long Term Follow-up of HPV Vaccine in HIV (CTN 236)
The purpose of this extension study is to determine whether HPV antibody levels in HIV-positive girls and women will decline more rapidly and more significantly than in HIV-negative girls and women and if this decline is…
- Conditions
- Cervical Cancer, Human Papillomavirus Infection, Human Immunodeficiency Virus, Cervical Dysplasia
- Trial name
- NCT06915779
- Where
- 13 sites in Canada
- Volunteers
- 241 people
- Sponsor
- University of British Columbia
Arthritis, Juvenile, Arthritis, Childhood
Feasibility of a Diet Intervention for Juvenile Arthritis
Families of children with arthritis are highly interested in the benefits of diet to improve their child's disease and future health outcomes.
- Conditions
- Arthritis, Juvenile, Arthritis, Childhood, Juvenile Idiopathic Arthritis
- Trial name
- DIGEST-JA (NCT06474546)
- Testing
- Diet intervention
- Where
- 7 sites in Canada
- Volunteers
- 54 people
- Sponsor
- The Hospital for Sick Children
Acne Vulgaris
Open-Label, Randomized Study Evaluating the Absorption and Systemic Pharmacokinetics of Topically Applied IDP-126 Gel in Comparison With Control Gel
This will be an open-label study designed to assess the safety and plasma PK of topically applied IDP-126 Gel compared to Control Gel.
- Trial name
- NCT03653403
- Testing
- IDP-126 Gel, Control Gel
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Bausch Health Americas, Inc.
Juvenile Idiopathic Arthritis (JIA)
YOGA FOR CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS
Juvenile Idiopathic Arthritis (JIA) is a chronic autoimmune condition starting before age 16, often leading to fatigue, joint stiffness, and decreased physical activity.
- Trial name
- JIA (NCT07661069)
- Testing
- Telerehabilitation-Based Yoga Group, Standard Home-Based Physical Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Akdeniz University
Dermatitis, Atopic
Study Of Atopic Dermatitis In Pediatrics
To verify of cetirizine dry syrup to ketotifen dry syrup in the change in the severity of pruritus of the treatment period.
- Trial name
- NCT00257569
- Testing
- Cetirizine Dry Syrup
- Volunteers
- 278 people
- Sponsor
- GlaxoSmithKline
PCSK9
Proprotein Convertase Subtilisin Kexin 9 in Rheumatoid Arthritis
Rheumatoid arthritis (RA) has been proved to increase the incidence of atrial fibrillation (AF) with persistent systemic inflammation.
- Trial name
- NCT05191342
- Testing
- Enzyme-linked immunosorbent assay for PCSK9
- Where
- 2 sites in China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
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