Clinical trials: Skin Tests
Diabetes Mellitus, Hypertension
Evidence-based Laboratory Test Order Sets in Primary Care
Cluster randomised controlled trial to evaluate what the effect is of evidence-based order sets aimed at five indications on the appropriateness of laboratory test ordering in primary care.
- Conditions
- Diabetes Mellitus, Hypertension, Cardiovascular Diseases, Fatigue
- Trial name
- NCT02950142
- Testing
- CPOE with order sets for lab testing, CPOE without order sets for lab testing
- Where
- Belgium
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Foramen Ovale, Patent, Nickel Sensitivity
Investigation of Nickel Sensitization After Percutaneous Implantation of Patent Foramen Ovale Occluder
Percutaneous PFO closure has been established as a first-line therapy for preventing recurrent strokes in selected patients. The devices used for the specific purpose contain and release nickel, which is considered as the most…
- Conditions
- Foramen Ovale, Patent, Nickel Sensitivity, Dermatitis Contact Irritant, Metal Allergy
- Trial name
- INSPIRE (NCT04713683)
- Testing
- Percutaneous Patent Foramen Ovale Closure
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- National and Kapodistrian University of Athens
Breast Neoplasms, Ovarian Neoplasms
Outcomes of Education and Counseling for BRCA1 Testing
This study will identify how personal beliefs, values and family experiences affect a person's decision as to whether or not to be tested for changes in a gene called BRCA1 or BRCA2.
- Trial name
- NCT00001468
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Contact Dermatitis
Clinical Evaluation of Metal Panel Allergens: Mercury, Aluminum and Palladium Dose Response Study
The purpose of this study is to evaluate the diagnostic performance and safety of ascending doses of mercury, aluminum and palladium metal allergens proposed for inclusion in a metal allergen panel.
- Trial name
- NCT02028208
- Testing
- Ammoniated mercury, Aluminum chloride and aluminum lactate, Sodium tetrachloropalladate
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Allerderm
Latent Tuberculosis
GXT - GeneXpert or Chest-X-ray or Tuberculin Skin Testing for Household Contact Assessment
The objective of the study is to compare outcomes from three different strategies for the management of household (HH) contacts of individuals with newly diagnosed microbiologically confirmed active pulmonary TB.
- Trial name
- NCT04528823
- Testing
- Strategy 2: Symptom screen, Genexpert and TST, Strategy 3:Symptom screen, CXR but NO TST
- Where
- 4 sites in Benin, Brazil
- Volunteers
- 1,589 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Catheter-related Bloodstream Infection
Recent Techniques for Diagnosing Central Venous Catheter-related Bloodstream Infections in Children
Removal of a central venous catheter (CVC) is often useful to prove its responsibility in a bloodstream infection. To avoid unnecessary removal of CVC, some catheter-spearing diagnostic methods have been recently developed.
- Trial name
- Incat (NCT01249976)
- Testing
- blood culture
- Where
- France
- Volunteers
- 148 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lupus Erythematosus, Systemic
Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE)
The purpose of this study is: 1. To assess the efficacy of a lipid-lowering agent (atorvastatin) on the development of atherosclerosis that predisposes children with SLE to cardiovascular events in adulthood. 2.
- Trial name
- NCT00065806
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Laura Schanberg
Asthma, Allergic Rhinitis
Fractional Exhaled Nitric Oxide (FeNO) Result Prediction Factors in Children With Allergic Diseases
In about 800 children with allergic diseases (asthma, allergic rhinitis, atopic dermatitis) the investigators will retrospectively and cross-sectionally analyze the influence/correlation of diagnosis, treatment methods, allergy…
- Conditions
- Asthma, Allergic Rhinitis, Atopic Dermatitis
- Trial name
- NCT00815984
- Testing
- measurements of lung function tests
- Where
- Poland
- Volunteers
- 800 people
- Sponsor
- Medical University of Lodz
Precancerous Condition
T4N5 Liposome Lotion Compared With Placebo Lotion for Preventing Actinic Keratoses in Patients With Xeroderma Pigmentosum
RATIONALE: Patients with xeroderma pigmentosum are more likely to develop skin lesions in sun-affected areas. These skin lesions, such as actinic keratoses, can develop into skin cancer.
- Trial name
- NCT00002811
- Testing
- liposomal T4N5 lotion
- Where
- 9 sites in United States, Germany and 1 more
- Volunteers
- 30 people
- Sponsor
- Applied Genetics
Leg Ulcers, Varicose Ulcers
Legtest Multi Centre Testing of the Lively Legs Program for Promoting Compliance in Leg Ulcer Patients
Leg ulcers are often chronic or recurring complications of peripheral circulation disorders. Patients' lifestyles are known to influence leg ulcer occurrence and circulation disorders in general.
- Trial name
- NCT00184873
- Testing
- Health Counseling
- Where
- 11 sites in Netherlands
- Volunteers
- 180 people
- Sponsor
- Radboud University Medical Center
Atopic Dermatitis
PRAgmatic Trial in Atopic Dermatitis Testing Long-term Control Effectiveness of New Phototherapy Regimen During Winter Coupled With Oral Vitamin D Supplementation vs. Placebo
Spaced phototherapy sessions during winter as add-on therapy in combination with vitamin D supplementation or not, could be beneficial to improve disease LTC in AD patients
- Trial name
- PRADA (NCT02537509)
- Testing
- Cholecalciferol
- Where
- 11 sites in France
- Volunteers
- 111 people
- Sponsor
- Rennes University Hospital
Mesothelioma, Lung Neoplasms
Chest Wall Motion Analysis in Disease
Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest.
- Conditions
- Mesothelioma, Lung Neoplasms, Surgery, Cystic Fibrosis
- Trial name
- CWM (NCT02958683)
- Testing
- Chest wall motion analysis
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Heart of England NHS Trust
Food Allergy, Food Allergy in Infants
The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy
The BAT Impact study is a prospective multicentre study in the UK using a biomarker-led study design to compare the incidence of adverse events (defined as allergic reactions during oral food challenges) in a…
- Conditions
- Food Allergy, Food Allergy in Infants, Food Allergy in Children, Food Allergen Sensitisation
- Trial name
- NCT05309772
- Testing
- Basophil activation test (BAT), Oral food challenge (OFC)
- Where
- 11 sites in United Kingdom
- Volunteers
- 398 people
- Sponsor
- King's College London
Food Allergy, Quality of Life
The Feasibility of Systemic Reaction After Contact Exposure to the Allergenic Food in Children With Known Food Allergy
The prevalence of food allergy in the western world is a growing health problem. The majority of reactions are caused due to oral exposure to the known food allergen.
- Trial name
- NCT05080127
- Testing
- application of the allergenic food
- Where
- 2 sites in Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Sickle Cell Leg Ulcer
Test of the Safety, Effectiveness, & Acceptability of An Improvised Dressing for Sickle Cell Leg Ulcers in the Tropics
One in 300 Jamaicans have HbSS sickle cell disease, and of these, up to 70% will suffer from sickle cell leg ulcers (SCLUs). Of these, 24% will have a chronic SCLU (one lasting longer than 6 months).
- Trial name
- SCLUJamaica (NCT04479618)
- Testing
- Usual Practice, Improvised dressing, Advanced dressing
- Where
- Jamaica
- Volunteers
- 48 people
- Sponsor
- Benskin, Linda, PhD, RN, SRN (Ghana), CWCN, CWS, DAPWCA
Sensitization to Legumes
Prevalence of Sensitization to Legumes in a Region From Southern France (Légumineuses)
The Mediterranean diet is a model for health. Indeed, according to some epidemiological studies, it would participate in the prevention of various diseases such as cardiovascular diseases, diabetes type 2, cancer and obesity.
- Trial name
- Légumineuses (NCT03686891)
- Testing
- Skin prick tests with four native legumes
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Montpellier
Skin Hyperpigmentation, Dry Skin; Eczema
Efficacy and Safety Assessment of Niacinamide Cosmetic Preparation: a Randomized Controlled Trial
Niacinamide in lower concentrations has been recognized as a cosmetic ingredient with hydrating properties. Therefore, aim was to test the efficacy and safety of niacinamide cosmetic preparation in A Randomized, Controlled Trial.
- Trial name
- NCT06189105
- Testing
- miss alice face it you love me serum, No treatment (usual skincare rutine)
- Where
- Croatia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
IgE-Mediated Hypersensitivity, Allergy
Safety of Ertapenem in Beta-lactam Allergic Patients.
The purpose of this study is to assess cross-reactivity and tolerability of ertapenem in patients with IgE-mediated allergy to at least one beta-lactam molecule.
- Trial name
- NCT01159379
- Testing
- ertapenem
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Catholic University of the Sacred Heart
Generalized Pustular Psoriasis
Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With Generalized Pustular Psoriasis Who Took Part in a Previous Study
This study is open to people with generalized pustular psoriasis (GPP). People can only take part if they have completed treatment in a previous study with spesolimab (1368-0013 or 1368-0027).
- Trial name
- NCT03886246
- Testing
- Spesolimab
- Where
- 58 sites in United States, Argentina and 19 more
- Volunteers
- 131 people
- Sponsor
- LEO Pharma
Rheumatic Disease, Rheumatoid Arthritis
The Usefulness of Interferon-γ Release Assays and Tuberculin Skin Test for Detection of Latent Tuberculosis Infection
The purposes of this study 1. to compare the positivity of tuberculin skin test(TST) and QuantiFERON-TB Gold (QFT-G), and determine the level of agreement between two tests in patients with rheumatic diseases 2.
- Conditions
- Rheumatic Disease, Rheumatoid Arthritis, Ankylosing Spondylitis, Tuberculosis
- Trial name
- NCT01685905
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Hanyang University