Clinical trials: Skull Defect
Zygomaticomaxillary Complex Fracture, Orbital Floor Fractures
Evaluating The Prebent Titanium Mesh for Zygomatico-Orbital Reconstruction in Twelve Patients Measuring Multiple Ophthalmologic Parameters, Aesthetic Results, Orbital Volume, Area of Bone Defect, Layout Angle, Gab Length and The Accuracy of Reconstruction
Purpose: The aim of this study was to evaluate the role of using a prebent titanium mesh on a 3D-printed model as an intraoperative guide to reconstruct orbito-zygomatic-maxillary complex (OZMC) fractures.
- Conditions
- Zygomaticomaxillary Complex Fracture, Orbital Floor Fractures, Ophthalmic Trauma
- Trial name
- NCT07103187
- Testing
- Zygomatico-Orbital reconstruction
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Tanta University
Brain Injuries, Hematoma of Head
Comparison of Cranioplasty With PEEK and Titanium
Decompressive craniectomy is suggested as an effective surgical intervention for patients with high intracranial pressure. Recently, various customized artificial materials are increasingly employed, e.g., titanium and…
- Conditions
- Brain Injuries, Hematoma of Head, Skull Defect
- Trial name
- NCT04707404
- Testing
- Cranioplasty
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Cranial Bone Defect, Orbital Base Fracture
Clinical Study of FRC Implant to Treat Skull Bone Defects
Bioactive fibre-reinforced composite implant is used for reconstruction of skull bone defects and orbital floor defects. Functional and aesthetic outcome is assessed by patient and doctor.
- Trial name
- Cranio-2 (NCT01874613)
- Testing
- FRC implant reconstruction
- Where
- Finland
- Volunteers
- 19 people
- Sponsor
- Turku University Hospital
Cranioplasty, Disability Physical
Does Cranioplasty Reduce Disability in Cases With Post Traumatic Skull Bone Defects
Background: The percentage of permanent infirmities following traumatic cranial bone cranial bone defects following trauma for restoration of function and cosmoses.
- Conditions
- Cranioplasty, Disability Physical, Trauma
- Trial name
- Cranioplasty (NCT04111562)
- Testing
- Cranioplasty
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Assiut University
Craniosynostosis
Network Of Clinical Research Studies On Craniosynostosis, Skull Malformations With Premature Fusion Of Skull Bones
Craniosynostosis (CS) is a common malformation occurring in ~4 per 10,000 live births in which the sutures between skull bones close too early, causing long-term problems with brain and skull growth.
- Trial name
- NCT03025763
- Testing
- Craniosynostosis Network Environmental Survey, 2D/3D Photography, Buccal Swab Cell Sampling
- Where
- 20 sites in United States, France and 3 more
- Volunteers
- 2,145 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Skull Defect
Development of Three-dimensional Deep Learning for Automatic Design of Skull Implants
This project aims to develop an effective deep learning system to generate numerical implant geometry based on 3D defective skull models from CT scans.
- Trial name
- NCT05603949
- Testing
- 3D deep learning neural network system
- Where
- Taiwan
- Volunteers
- 6 people
- Sponsor
- Chang Gung Memorial Hospital
Craniofacial Defects, Subtle, Skull Defect
Functionalized Bioink Delivering Biomolecules for the Treatment of Craniofacial Diseases
The study aims to address the challenges of craniofacial bone reconstruction in pediatric and adult patients affected by congenital craniofacial malformations (i.e.
- Conditions
- Craniofacial Defects, Subtle, Skull Defect, Craniosynostoses
- Trial name
- DART-CRAFT (NCT06533150)
- Testing
- multiomic profiling
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Plagiocephaly, Cranial Defect
Associations of Cranial Outcomes and Parental Expectations and Satisfaction
This study aims to investigate the association between objective cranial morphological changes and parental expectations and satisfaction in infants undergoing treatment with a cranial remolding orthosis (CRO).
- Conditions
- Plagiocephaly, Cranial Defect, Orthosis, Expectancy
- Trial name
- NCT07356401
- Testing
- Cranial orthosis
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Gulhane School of Medicine