Clinical trials: Sleep Disordered-breathing
Sleep Apnea Syndromes
Parent-QoL and Sleep Disordered Breathing
In this prospective case-control study the investigators will enrolled parents of 45 children younger than five years of age who were planned to undergo adenotonsillectomy due to an obstructive airway indication in an academic…
- Trial name
- NCT04501848
- Testing
- adenotonsillectomy
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Obstructive Sleep Apnea, Orthodontic Tooth Movement
The Effect of Tooth Position During Orthodontic Treatment on the Apnea/ Hypopnea Index (AHI)
The study design of this research project involves orthodontic patients registered at the Harvard School of Dental Medicine who are deemed eligible to undergo orthodontic treatment and who have been provided with sufficient…
- Conditions
- Obstructive Sleep Apnea, Orthodontic Tooth Movement, Apnea, Sleep Disordered Breathing
- Trial name
- NCT03299023
- Testing
- Medibyte Portable Monitor
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Sleep-disordered Breathing
Leukotrienes Pathway in Chinese Children With Sleep-disordered Breathing
Our goals are to demonstrate an active leukotrienes (LTs) mediated inflammatory response is involved in pathophysiology of sleep-disordered breathing (SDB), and to provide a theoretical evidence for LTs modify therapy in treating…
- Trial name
- NCT01344746
- Where
- China
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Beijing Children's Hospital
SDB, T2DM
Sleep Disordered Breathing and Impaired Glucose Homeostasis in Obese Children
SDB has been identified as an important risk factor for insulin resistance and the metabolic syndrome. In a recent study in patients with SDB and T2DM it was shown that CPAP therapy can lead to improvements in postprandial…
- Conditions
- SDB, T2DM, Obesity
- Trial name
- NCT02037100
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Autonomic Dysfunction
Autonomic Regulation in Prader-Willi Syndrome
To evaluate autonomic regulation in patients with Prader-Willi syndrome with sleep-disordered breathing.
- Trial name
- NCT04118816
- Testing
- Polysomnography, Multiple sleep latency test, Continuous positive airway pressure
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Blood Oxygen Desaturations, Sleep-Disordered Breathing
Assessment of the Accuracy of the Non-invasive Wireless Armband Gabi Baby Band for Continuous Vital Parameters Monitoring in Infants and Young Children
During a polysomnography test (PSG) previously prescribed by a physician, the patient also wears the Gaby Baby Band (GBB) during an entire night of sleep.
- Trial name
- WAGSC1 (NCT04886583)
- Testing
- Gabi Baby Band
- Where
- 3 sites in Belgium
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Gabi SmartCare
Cleft Palate
Sleep and Behavior in Children With Cleft Palate
The purpose of this study is to determine whether cleft palate repair increases the risk for obstructive sleep apnea in children and whether sleep apnea could explain learning and behavior difficulties that are often observed.
- Trial name
- NCT01046591
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Early Risk Screening for Sleep Disordered Breathing in a Dental Setting, Sleep Disordered Breathing (SDB)
Early Dental Risk Screening for Pediatric Sleep-Disordered Breathing
This is a prospective, cross-sectional observational study designed to evaluate the Pediatric Sleep Questionnaire (PSQ) as a screening tool for sleep-disordered breathing (SDB) risk in a pediatric dental setting.
- Conditions
- Early Risk Screening for Sleep Disordered Breathing in a Dental Setting, Sleep Disordered Breathing (SDB), Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07581938
- Testing
- SleepImage Ring
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Sleep Apnea Syndromes, Sleep Disorder
WatchPAT Device Validation Study Compared to Polysomnography
Validation study of a novel sleep Device compared to a traditional sleep study.
- Conditions
- Sleep Apnea Syndromes, Sleep Disorder, Sleep
- Trial name
- WPAT (NCT03188718)
- Testing
- WatchPAT Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obstructive Sleep Apnea, Obesity
Obesity and Obstructive Sleep Apnea (OSA) in Children
The goal of this research is to study the prevalence of sleep disordered breathing and associated morbidity in obese children and to examine the role of diet and physical activity in the treatment of sleep-disordered breathing in…
- Trial name
- NCT01135147
- Testing
- Diet, Surgery
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Pregnant Women
Fetal Outcome of Sleep Disordered Breathing During Pregnancy
Sleep disordered breathing (SDB) is a frequent disorder characterized by some combination of repeated events of partial or complete upper airway obstruction during sleep, disruption of normal ventilation, hypoxemia, and sleep…
- Trial name
- NCT00931099
- Where
- Israel
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Sleep Disordered Breathing (SDB), Sleep Apnea
Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study
Sleep disordered breathing (SDB) is one of the most common sleep disorders, including obstructive sleep apnea (OSA), central sleep apnea (CSA), sleep-related hypoventilation, hypoxemia, etc., with OSA being the most prevalent.
- Conditions
- Sleep Disordered Breathing (SDB), Sleep Apnea, Cardiometabolic Diseases, Multimorbidity
- Trial name
- NCT06755840
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Sleep Related Breathing Disorder, Upper Airway Resistance Syndrome
Inferior Turbinate Reduction in Pediatric Population Failing Surgery for Sleep Disordered Breathing
This study will examine whether treatment of inferior turbinates in patients with continued symptoms of obstructive sleep apnea, sleep related breathing disorder, snoring, disturbed sleeping, open mouth breathing, and upper…
- Conditions
- Sleep Related Breathing Disorder, Upper Airway Resistance Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT00936494
- Testing
- Cold ablation inferior turbinate reduction
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Sleep, Sleep Apnea Syndromes
Identification of Sleep-Disordered Breathing in Children
The purpose of this research is to study and improve the methods used to detect childhood breathing problems during sleep that can affect daytime behavior at home and school.
- Conditions
- Sleep, Sleep Apnea Syndromes, Sleep Disordered Breathing
- Trial name
- NCT00233194
- Testing
- Observational follow-up study of adenotonsillectomy
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sleep Disordered Breathing (SDB), Endothelial Dysfunction
Sleep Disordered Breathing in Children: Inflammation and Oxidative Stress
The purpose of the study is to measure markers of inflammatory and oxidative stress known to be associated with cardiovascular morbidity in snoring children.
- Trial name
- NCT02040701
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obesity & Overweight Sleep, Obstructive Sleep Disordered Breathing
Ultrasound Assessment of Tongue Characteristics in Adolescents With Obesity and Obstructive Sleep Disorders
Obstructive sleep-disordered breathing, including obstructive sleep apnea (OSA), represents a significant yet underdiagnosed condition in the pediatric population, particularly among adolescents with obesity.
- Conditions
- Obesity & Overweight Sleep, Obstructive Sleep Disordered Breathing, Pediatric Obesity
- Trial name
- NCT07613944
- Testing
- Submental ultrasound
- Where
- 2 sites in Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Sleep-disordered Breathing, Sleep Apnea, Obstructive
Behavioral Effects of Obstructive Sleep Apnea in Children
Sleep-disordered breathing (SDB) in children may be responsible for disruptive daytime behaviors such as inattention and hyperactivity. Many children undergo tonsillectomy for SDB and disruptive daytime behaviors.
- Conditions
- Sleep-disordered Breathing, Sleep Apnea, Obstructive, ADHD
- Trial name
- NCT00060723
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anemia, Sickle Cell, Sleep-Disordered Breathing
SMILES: Study of Montelukast in Sickle Cell Disease
Sickle cell disease (SCD) is a genetic blood condition causing long term health problems including pain and brain problems which affect quality of life.
- Trial name
- SMILES (NCT04351698)
- Testing
- Montelukast
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Sleep Disorders in Children, Environmental Exposure
Environmental Assessment of Sleep in Youth
In this research study, investigators want to learn more about the factors that influence children's breathing during sleep and their sleep quality.
- Trial name
- EASY (NCT03224455)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital