Clinical trials: Sleep Wake Disorders
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Insomnia
Investigation of the Safety and Efficacy of Long Term Administration of Eszopiclone in Insomnia Patients
To investigate the safety and efficacy of administration of eszopiclone for 6 months in insomnia participants.
- Trial name
- NCT02455271
- Testing
- Eszopiclone
- Where
- 2 sites in Japan
- Volunteers
- 438 people
- Sponsor
- Eisai Co., Ltd.
Preterm, Chronobiology
The Effect of Oral Feeding Model With a Chronobiological Approach in Neonates
The ideal food for healthy term babies as well as preterm babies and sick term babies is breast milk. There are many studies showing that the composition of breast milk can vary from mother to mother, according to the baby's…
- Conditions
- Preterm, Chronobiology, Human Milk/Breastfeeding, Bottle Feeding
- Trial name
- NCT06821672
- Testing
- Chronobiological Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Androgenetic Alopecia, Hair Loss
Efficacy of Platelet-Rich Plasma Versus Mesotherapy in Androgenetic Alopecia: A Retrospective Study
This is a comparative retrospective study of the efficacy of platelet-rich plasma injections and injections with commercial products advertised to promote hair regrowth for patients with androgenetic alopecia.
- Conditions
- Androgenetic Alopecia, Hair Loss, Alopecia
- Trial name
- NCT05129800
- Testing
- Platelet-rich plasma, Mesotherapy
- Volunteers
- 72 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Rheumatic Diseases, Arthritis
Pain-Sleep in Rheumatic Disease
Overall, our understanding of how pain and sleep are experienced and how they can be treated in teenagers with rheumatic diseases is limited.
- Conditions
- Rheumatic Diseases, Arthritis, Lupus, Lupus Arthritis, Systemic Lupus Erythematosus
- Trial name
- NCT07775612
- Testing
- Better Nights, Better Days for Youth
- Volunteers
- 43 people
- Sponsor
- The Hospital for Sick Children
Ehlers-Danlos Syndrome, Obstructive Sleep Apnea
Obstructive Sleep Apnoea in Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
- Trial name
- OSA in EDS (NCT02435745)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sleep Disturbance, Sleep Deprivation
Behavioral Sleep Intervention in Urban Primary Care: Aim 3
Investigators will enroll up to 120 parent-child dyads from Children's Hospital of Philadelphia (CHOP) urban primary care clinics.
- Conditions
- Sleep Disturbance, Sleep Deprivation, Sleep
- Trial name
- NCT04473222
- Testing
- Sleep Well!, Sleep education
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Children's Hospital of Philadelphia
Obstructive Sleep Apnea, Sleep Disorder
Validation of Pediatric Sleep Questionnaire on a Swedish Cohort
This study is aimed to validate the questionnaire called Pediatric Sleep Questionnaire on a Swedish cohort of children from 18 months to 15 years old with obstructive sleep disordered breathing.
- Conditions
- Obstructive Sleep Apnea, Sleep Disorder, Sleep Disorders in Children, Obstructive Sleep Apnea of Child
- Trial name
- NCT06367400
- Testing
- Pediatric Sleep Questionnaire
- Where
- Sweden
- Volunteers
- 520 people
- Sponsor
- Uppsala University
Femoral Neck Fracture
Interest of the OSA (Obstructive Sleep Apnea) Predictive Scores in the Prognosis of Postoperative Mortality of Femoral Neck Fractures
Interest of the four major OSA Predictive Scores (STOP-BANG, P-SAP, DES-OSA, OSA50) in the prognosis of postoperative mortality after femoral neck fracture.
- Trial name
- NCT02202122
- Testing
- OSA Scoring
- Where
- Belgium
- Sponsor
- Astes
Parkinson Disease, REM Sleep Behavior Disorder (iRBD)
Role of Slow Waves in the Progression of Neurodegeneration in Isolated REM Sleep Behavior Disorder
This study tests whether enhancing deep sleep with gentle sounds at night can slow progression in people with iRBD or early Parkinson's disease. Participants wear a sensor headband and headphones for 18 months.
- Trial name
- SloW-iRBD (NCT07355842)
- Testing
- Tosoo Axora
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Obstructive Sleep Apnea
Comparing Fitbit® Quality of Measured Sleep to Sleep Measured by Polysomnography in the Sleep Lab
This study is to evaluate a commercial tool on the market (Fitbit®) that also quantifies sleep. No one has studied how pediatric patients perform with it and how accurate it is in measuring their quality of sleep.
- Trial name
- NCT03066479
- Testing
- Fitbit, OSA questionnaire, Polysomnography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vidya Raman
Narcolepsy Type 1, Narcolepsy Type 2
Improving Social Relationships for Adolescents With Central Disorders of Hypersomnolence
The goal of this study is to test a web-based psychoeducational resource for adolescents with central disorders of hypersomnolence and their families.
- Conditions
- Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia
- Trial name
- NCT06251063
- Testing
- Web-based psychoeducational resource
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Boston Children's Hospital
Heat Stress
Heat Stress Exposure Among Low-Income Residents in Bangladesh and Evaluation of Indoor Interventions
The goal of this clinical trial is to learn if infrastructure and equipment installed to cool homes reduce adverse health outcomes.
- Trial name
- NCT06979258
- Testing
- Cooling intervention
- Where
- Bangladesh
- Volunteers
- 1,539 people
- Sponsor
- University of California, Berkeley
Insomnia, Delayed Sleep Phase Disorder
Blue-blocking Glasses for Sleep Disorders in Child and Adolescent Psychiatry
Sleep problems and regulation difficulties are frequent in the child and adolescent psychiatry population. Insomnia and delayed sleep-wake phase disorders (DSPWD) are highly prevalent, and risk factors for developing more severe…
- Conditions
- Insomnia, Delayed Sleep Phase Disorder, Hyperarousal, Transdiagnostic Psychopathology
- Trial name
- BATCAT-pilot (NCT07433491)
- Testing
- Blue-blocking glasses (BB-glasses) or real darkness from 9 p.m. to desired wake-up time + night mode setting on mobile phone, Control
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Helse Fonna
Stem Cell Transplant Complications, Sleep Disturbance
Developing Restful Environments and Management Strategies for Pediatric Stem Cell Transplant Patients
Pediatric patients undergoing stem cell transplant (SCT) are hospitalized for extended periods and are at high risk for sleep disturbances.
- Trial name
- DREAMS (NCT06468618)
- Testing
- DREAMS Program Video and Care Kit
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
Insomnia, Anxiety
Efficacy of Group Cognitive Behavioural Therapy for Youth Anxiety and Insomnia
Youth is an important transitional stage associated with dynamic changes in biological, cognitive, and psychological functioning, as well as a constellation of developmental and psychosocial challenges.
- Trial name
- NCT06054243
- Testing
- CBT-I, CBT-A
- Where
- Hong Kong
- Volunteers
- 137 people
- Sponsor
- The University of Hong Kong
Substance Use, Stress
Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School
Deviant peer affiliation is one of the most important predictors of alcohol use in adolescence. These affiliations arise when socially marginalized youth self-aggregate and reinforce alcohol use and other deviant activity (i.e.…
- Conditions
- Substance Use, Stress, Relation, Interpersonal, Bullying
- Trial name
- PeerLearning (NCT04478240)
- Testing
- PeerLearning.net
- Where
- United States
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Blindness
Young Blind Child Melatonin Treatment Study
The primary goal of this study is to identify the presence of desynchronized circadian rhythms in 25 children by measuring melatonin secretion in serial blood or saliva samples, and to rule out any primary sleep disorders.
- Trial name
- NCT00688935
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Oregon Health and Science University
Dementia, Alzheimer Disease
Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders
The Multidisciplinary Expert System for the Assessment \& Management of Complex Brain Disorders (MES-CoBraD) is an interdisciplinary project combining Real-World Data (RWD) from multiple clinical and consumer sources through…
- Conditions
- Dementia, Alzheimer Disease, Epilepsy, Sleep Disorder
- Trial name
- MES-CoBraD (NCT05171725)
- Testing
- EEG,PSG, biosample collection (blood and CSF), neuropsychological testing
- Where
- 4 sites in Greece, Israel and 2 more
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Neurological Institute of Athens
Breathing Disorder During Sleeping, Sleep Habits
Impact of Palatal Expansion and Up-Locker Activator on Sleep and Pharyngeal Dimensions in Children
Objective: The study will aim to compare the effect of palatal expansion with Hyrax and Hyrax combined with Up-Locker on sleep behavior, sleep architecture, quality of life and nasal and pharyngeal airway dimensions, as well as…
- Trial name
- NCT06986343
- Testing
- Hyrax, Hyrax and Uplocker Vacuum Device
- Where
- Colombia
- Volunteers
- 34 people
- Sponsor
- CES University