Clinical trials: Sleep-Wake Disorders
Sleep, Sleep Disturbance
Sleep Promotion Program Primary Care (SPP PC) Open Trial
Investigators developed a brief, scalable, behavioral Sleep Promotion Program (SPP) for adolescents with short sleep duration and sleep-wake irregularity, which relies on one individual session and smart phone technology to…
- Conditions
- Sleep, Sleep Disturbance, Insufficient Sleep
- Trial name
- SPP OT (NCT06239792)
- Testing
- Sleep Promotion Program
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pittsburgh
Borderline Personality Disorder, Sleep Disturbance
Real-time Experiences With Sleep Training Study
Borderline personality disorder (BPD) is a serious mental illness that often first emerges in adolescence. Effective treatments are typically expensive, lengthy, and intense (e.g., Dialectical Behavior Therapy).
- Trial name
- REST (NCT04507308)
- Testing
- Single-session sleep intervention drawn from principles of the TSC-youth protocol
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- University of Utah
Coronary Artery Disease, Obstructive Sleep Apnea
Continuous Positive Airway Pressure (CPAP) Treatment in Coronary Artery Disease and Sleep Apnea
Obstructive sleep apnea (OSA) worsens the prognosis in patients with coronary artery disease (CAD). Many of these subjects do not report daytime sleepiness, and therefore, are not considered for OSA treatment with continuous…
- Trial name
- RICCADSA (NCT00519597)
- Testing
- ResMed S8 (Auto-CPAP)
- Where
- Sweden
- Volunteers
- 511 people
- Sponsor
- Skaraborg Hospital
Autism Spectrum Disorder, Sleep Disorder
Effect of Snoezelen-Based Occupational Therapy Intervention on Sleep and Behavior Problems in Infant at Risk of Autism
Objective: Sleep and behavioral problems are common in infants at risk of autism. This study aims to examine the effect of Snoezelen-Based Occupational Therapy intervention on sleep and behavioral problems in infants at risk of…
- Conditions
- Autism Spectrum Disorder, Sleep Disorder, Behavior Problem
- Trial name
- NCT06164210
- Testing
- Snoezelen-Based Occupational Therapy Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ankara University
Healthy, Sleep Apnea
Confounding Factors of Impedance Pneumography
The purpose of this study is to evaluate the association of signals recorded and analysed with Ventica® Lung Function Testing System (LFTS) in infants and pre-schoolers during the whole night sleep with the gold standard for…
- Trial name
- NCT03408990
- Where
- Croatia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Revenio Research
Narcolepsy, Sleep Apnea, Obstructive
PROVIGIL® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome
The primary objective of the study is to evaluate the safety and tolerability of treatment with PROVIGIL in children and adolescents with excessive sleepiness (ES) associated with narcolepsy or OSAHS (obstructive sleep…
- Trial name
- NCT00107848
- Testing
- Modafinil
- Where
- 61 sites in United States, Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Cephalon
Hypoplastic Left Heart Syndrome, Obstructive Sleep Apnea Syndrome
Sleep Disordered Breathing in Children With Single Ventricle Physiology
This is an exploratory study designed to evaluate the incidence of, and to quantify sleep disordered breathing following stage I Norwood reconstructive surgery. Sleep disordered breathing will be correlated with: 1.
- Conditions
- Hypoplastic Left Heart Syndrome, Obstructive Sleep Apnea Syndrome, Single Ventricle Physiology
- Trial name
- NCT00156455
- Where
- United States
- Sponsor
- University of Rochester
Narcolepsy
Child and Adolescent Registry for Participants With Narcolepsy
CATNAP is a patient registry designed to improve the understanding of the natural history of narcolepsy in pediatric patients. Descriptive statistics on disease characteristics will be performed.
- Trial name
- NCT04899947
- Where
- 25 sites in United States
- Volunteers
- 500 people
- Sponsor
- Jazz Pharmaceuticals
Insomnia
Digital Cognitive Behavioral Treatment of Insomnia in Youth: An RCT Examining Feasibility, Acceptability, and Efficacy of NiteCAPP Jr
The proposed pilot will examine feasibility, acceptability, and preliminary efficacy of a digital CBT-I tailored for school-aged children.
- Trial name
- NiteCAPP JR (NCT07091149)
- Testing
- CBT-I
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of South Florida
Digital Screen Addiction and Sleep Quality in Adolescents
The Impact of Digital Detox Training on Screen Use, Sleep Quality, and Healthy Lifestyle Behaviors in Adolescents
This study evaluates the effects of a digital detox program on screen time, sleep quality, and healthy lifestyle behaviors among adolescents aged 10-19 years.
- Trial name
- DIGIDETOX-RCT (NCT07555834)
- Testing
- Digital Detox Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Şırnak Üniversitesi
Obstructive Sleep Apnea, Hypoventilation
The IPAd Study: Exploring the Association Between Insomnia and Positive Airway Pressure Adherence in Children
Sleep-disordered breathing (SDB) is prevalent in children and adolescents and untreated SDB impacts key indicators of physical and psychosocial health.
- Conditions
- Obstructive Sleep Apnea, Hypoventilation, Central Sleep Apnea
- Trial name
- IPAd (NCT05949164)
- Testing
- Insomnia
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- The Hospital for Sick Children
Narcolepsy
Study of the Academic and Professional Course of Narcoleptic Patients (NARCOSCOL-NARCOVITAE)
Narcolepsy is a chronic, disabling, and rare sleep disorder (prevalence 1/2500) characterized by excessive daytime sleepiness and, in some patients, falls in muscle tone related to emotions (cataplexies).
- Trial name
- NCT03765892
- Testing
- Questionnaire (Adult), Questionnaire (Children)
- Where
- 18 sites in France
- Volunteers
- 1,605 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Dry Eye Disease (DED)
Correlation of Dry Eye Disease, Problematic Smartphone Use and Sleep Quality in Adolescents and Young Adults
The goal of this observational study is to learn about the status quo and relationship of dry eye, problematic smartphone use, bedtime procrastination, and sleep in adolescents and young adults.
- Trial name
- NCT07020871
- Where
- China
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Acute Postoperative Pain, Thoracic Surgical Procedures
Transcutaneous Electrical Nerve Stimulation for Acute Postoperative Pain After Video-Assisted Thoracoscopic Surgery
This randomized, double-blind, sham-controlled study aims to evaluate the effects of transcutaneous electrical nerve stimulation (TENS) on acute postoperative pain, sleep quality, and quality of life in patients undergoing…
- Trial name
- NCT07732764
- Testing
- Active TENS
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Fooyin University
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Insomnia, Dementia
Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial
Insomnia is a highly common, chronic disorder that is distressful for the patient but also for caregivers and can give rise to a heavy burden on the healthcare team.
- Conditions
- Insomnia, Dementia, Frontotemporal Dementia
- Trial name
- NCT06093126
- Testing
- Lemborexant 5 MG
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Nova Scotia Health Authority
Obstructive Sleep Apnea
Clinical Evaluation of an Apnea Index for Diagnosis and Screening of Obstructive Sleep Apnea (OSA)
The study is designed to compare the apnea event recognition capability of the Capnostream 20 with investigational software to polysomnograph recordings scored by a trained analyst.
- Trial name
- NCT01010438
- Where
- 3 sites in Israel
- Volunteers
- 59 people
- Sponsor
- Oridion
Insomnia
Examining the Effectiveness of Two Behavioral Interventions for Sleep Problems in Infants
Behavioral insomnia of childhood affects 15-30% of infants. Behavioral interventions, based on limiting parent-child bedtime and nighttime interactions, are effective in significantly improving infant sleep problems.
- Trial name
- NCT05726890
- Testing
- bedtime intervention for early childhood insomnia, bedtime and nighttime intervention for early childhood insomnia
- Where
- Israel
- Volunteers
- 270 people
- Sponsor
- Ben-Gurion University of the Negev
Insomnia, Attention Deficit Hyperactivity Disorder
Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia
A multicenter study to evaluate the safety of eszopiclone in children (6 11 years of age, inclusive) and adolescents (12 17 years of age, inclusive) with attention deficit/hyperactivity disorder (ADHD) associated insomnia.
- Trial name
- NCT00857220
- Testing
- eszopiclone
- Where
- 89 sites in United States
- Volunteers
- 304 people
- Sponsor
- Sumitomo Pharma America, Inc.