Clinical trials: Spasticity, Muscle
Spastic Cerebral Palsy
Feasibility Nutritional Supplements for Muscle Growth in CP
The purpose of this study is to investigate the feasibility of a 10-week plan with a nutritional supplement (leucine) and to perform pilot analyses on the effect of leucine on macroscopic muscle morphology in children with…
- Trial name
- Nut-CP (NCT06044168)
- Testing
- Dietary Supplement: Leucine
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy, Upper Extremity Dysfunction
The Effect of Upper Extremity Strengthening on Functionality, Muscle Strength and Trunk in Children With Cerebral Palsy
Cerebral Palsy (CP) is an activity limitation, movement and posture deficiencies in early stage of life. In 80% of these children, upper extremity (UE) dysfunctions are observed, which leads to loss of quality of life, resulting…
- Conditions
- Cerebral Palsy, Upper Extremity Dysfunction, Upper Extremity Functions, Muscle Strength
- Trial name
- NCT05115695
- Testing
- traditional physiotherapy approach, muscle strengthening exercise/Proprioceptive Neuromuscular Facilitation (PNF)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Neurodevelopmental Disorders, Cerebral Palsy
Central Nervous System Stimulants and Physical Function in Children With Cerebral Palsy
The purpose of this study is to determine the effects of Central Nervous System Stimulants, represented by Methylphenidate and Modafinil, compared to placebo control on motor performance in children with Cerebral Palsy.
- Trial name
- CP (NCT05675098)
- Testing
- Methylphenidate, Modafinil
- Where
- Kuwait
- Volunteers
- 30 people
- Sponsor
- Kuwait University
Muscular Dystrophies, Muscle Myopathies
Genetic and Physical Study of Childhood Nerve and Muscle Disorders
Background: Some nerve and muscle disorders that start early in life (before age 25), like some forms of muscular dystrophy, can run in families. However, the genetic causes of these disorders are not known.
- Conditions
- Muscular Dystrophies, Muscle Myopathies, Hereditary Spastic Paraplegias, Inherited Neuropathies
- Trial name
- NCT01568658
- Where
- United States
- Volunteers
- 2,586 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Activities of Daily Living, Postural Control
Effect of Callisthenic Training on Mobility and ADL Performance in Spastic Diplegic Cerebral Palsy Patients
Almost 2 to 3 out of every 1000 children have Cerebral palsy in Pakistan.Spastic type of CP is dominant about 75%, diplegia (40%) and hemiplegic are (35.5%).Spastic diplegics have tightness of lower limb more than upper…
- Conditions
- Activities of Daily Living, Postural Control, Spasticity, Mobility
- Trial name
- NCT06966076
- Testing
- calisthenic training, Conventional physical therapy group
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Cerebral Palsy, Musculoskeletal Deformity
Neuromusculoskeletal Modeling of Muscle Spasticity
Cerebral palsy (CP) is a movement and posture disorder caused by an injury to the developing brain, with a prevalence in Sweden of about 2/1000 live births.
- Conditions
- Cerebral Palsy, Musculoskeletal Deformity, Spasticity, Muscle Strength
- Trial name
- NCT05447299
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Region Stockholm
Cerebral Palsy, Spasticity
Dutch National ITB Study in Children With Cerebral Palsy
The objective of this study is to determine the efficacy and safety of treatment with intrathecal baclofen for severe spasticity in children with cerebral palsy.
- Trial name
- NCT00367068
- Testing
- baclofen, intrathecal, infusion pump for intrathecal baclofen, Synchromed, Medtronic
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Maastricht University
Cerebral Palsy
Intrathecal Administration of Baclofen (ITB) to Cerebral Palsy Patients With Therapy-Resistant Spasticity
Evaluation of the effect of intrathecal administration of Baclofen on spasticity of cerebral palsy patients, by means of standardized and internationally accepted scales
- Trial name
- NCT00221611
- Testing
- Administration of intrathecal baclofen
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Cerebral Palsy, Dystonia
Surface EMG Biofeedback for Children With Cerebral Palsy
Movement disorders such as dystonia, hypertonia, and spasticity interfere with or prevent voluntary movement. Studies have suggested that using biofeedback to increase awareness of muscle activation can improve motor function in…
- Conditions
- Cerebral Palsy, Dystonia, Hypertonia, Spasticity
- Trial name
- NCT01681888
- Testing
- Sanger EMG Biofeedback Device
- Where
- United States
- Sponsor
- University of Southern California
Cerebral Palsy, Cerebral Palsy, Spastic
Physiotherapy After Botulinum Toxin Injection and Serial Casting
The effects of different physiotherapy programs on children with cerebral palsy who have been received botulinum toxin injection and serial casting application will be determined.
- Trial name
- NCT05312125
- Testing
- backward downhill walking, routine physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Gazi University
Cerebral Palsy (CP)
Fascial Manipulation in Cerebral Palsy Rehabilitation
The purpose of the study is to investigate the potential additional benefits of a relatively new physiotherapy method, fascial manipulation, in the rehabilitation of movement difficulties or other problems caused by CP (cerebral…
- Trial name
- CP fascia (NCT06837025)
- Testing
- Fascial manipulation
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Orton Orthopaedic Hospital
Spastic Cerebral Palsy
A Physical Therapy Program Targeting Lower Extremity Selective Motor Control in Children With Spastic Cerebral Palsy
The goal of this intervention study is to learn whether a physical therapy exercise camp called will improve leg movement (motor control) and functional ability in children with spastic CP who are between 5 and 18 years.
- Trial name
- NCT07310550
- Testing
- Selective movement of individual lower limb joints, Knee joint strengthening at high velocities, Ankle controlled gaming
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, Los Angeles
Spasticity, Post-Stroke
JCP Study of Investigation of Patient Background Characteristics
To collect the background characteristics of juvenile cerebral palsy patients aged 2-year or older prescribed BOTOX for the treatment of equines foot due to lower limb spasticity, compare them with those of patients whose deaths…
- Trial name
- NCT01332474
- Testing
- BOTOX
- Volunteers
- 326 people
- Sponsor
- GlaxoSmithKline
Spasticity, Muscle, Cerebral Palsy
Effect of Number of Pulses of Radial Extracorporeal Shock Wave Therapy on Hamstring Spasticity in Children With Cerebral Palsy
Cerebral palsy (CP) is a group of permanent disorders affecting movement and postural development that are caused by non-progressive disruptions of the brain, usually occurring during fetal period or infancy.
- Conditions
- Spasticity, Muscle, Cerebral Palsy, Child; Spastic
- Trial name
- NCT04546035
- Testing
- radial Extracorporeal Shockwave Therapy
- Where
- Indonesia
- Volunteers
- 13 people
- Sponsor
- Rizky Kusuma Wardhani
Cerebral Palsy, Spastic
Core Strength for Head Control and Quality of Life in Cerebral Palsy
The goal of this observational study is to examine the effect of an 8-week therapist-assisted core muscle strengthening program on head control, trunk stability, functional core strength, quality of life, and automatic righting…
- Trial name
- NCT07613515
- Testing
- Core Strength Training
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Cairo University
Cerebral Palsy, Spastic
Role Of Physical Therapy In Relieving Constipation In Children With Spastic Cerebral Palsy
This study was conducted to determine the effectiveness of Physical Therapy management in relieving constipation among Spastic Cerebral Palsy children.
- Trial name
- NCT03379038
- Testing
- Progressive Physical Therapy, Maintenance Physical Therapy
- Where
- Pakistan
- Volunteers
- 35 people
- Sponsor
- Isra University
Cerebral Palsy (CP), Typically Developing Children
The Effect of Perturbation Training on Reactive Balance in Children With Cerebral Palsy
The aim of this project was to evaluate whether perturbation training influences reflex modulation in children with spastic CP and whether changed reflex modulation leads to improved reactive balance and walking.
- Trial name
- NCT07818928
- Testing
- Balance training on a moving platform
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy (CP), Spasticity Due to Cerebral Palsy
Effect of Botulinum Toxin Type A on Motor Function in Children With Cerebral Palsy
Project Identification and Researchers Title: "Changes in functionality and quality of life when applying the botulinum toxin type A infiltration protocol in children and adolescents with cerebral palsy of the spastic hemiparesis…
- Conditions
- Cerebral Palsy (CP), Spasticity Due to Cerebral Palsy, Hemiparesis
- Trial name
- NCT07034547
- Testing
- Botulinum toxin infiltration
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Instituto Teletón Chile
Cerebral Palsy, Spastic
Effect of Vibration on Muscle Properties, Physical Activity and Balance in Children with Cerebral Palsy
The aim of the 6-month randomized controlled trial, with 6-month no treatment follow-up, is to examine the effects of low-magnitude vibration on muscle, physical activity, and balance in children with spastic cerebral palsy.
- Trial name
- NCT03484078
- Testing
- Vibration Platform
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Georgia
C10.228.140.140.254
The Socioeconomic Status and Child Characteristics on the Physical Therapy Outcome in Children With Spastic Cerebral Palsy
The main outcome of physical therapy interventions is the progress of gross motor functions which result from the interactions between many factors not limited to physical, medical or surgical interventions but also including…
- Trial name
- NCT04160403
- Testing
- physical therapy intervention
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zeinab Hussein