Clinical trials: Specificity
Anxiety Disorders
Family and Peer Involvement in the Treatment of Anxiety Disorders in Children
This study will compare the effectiveness of family- and peer-oriented therapy in treating children with anxiety disorders and will also test for therapy specificity effects and potential mediators of outcome.
- Trial name
- NCT00073645
- Testing
- Peer/Group CBT, Family/Parents CBT
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Florida International University
Dengue
Clinical Trial of Diagnostic Tests and Clinical Algorithms for Dengue in Febrile Subjects in Endemic Areas in Colombia
The present study aimed to develop a sensitive dengue diagnostic clinical algorithm using the resources that are available at the health care institutions, clinical expertise, and identification of signs and symptoms and…
- Trial name
- NCT04063774
- Testing
- Dengue calculator
- Where
- 3 sites in Colombia
- Volunteers
- 1,045 people
- Sponsor
- Lyda Osorio
Streptococcal Pharyngitis
Diagnostic Accuracy of Rapid Molecular Tests for Group A Streptococcal Pharyngitis Using Saliva Samples
Observational study evaluating the diagnostic accuracy of rapid point-of-care molecular Group A strep diagnostic tests in saliva as compared to standard culture- and PCR-based techniques for the management of children aged 3-15…
- Trial name
- NCT05521568
- Testing
- Index test: Abbott ID NOW STREP A 2, Reference standard test: Composite of culture and PCR-based tests based on a throat swab, Comparator test: Rapid antigen detection test (usual care)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Multiple Myeloma
A Feasibility and Safety Study of Dual Specificity CD38 and BCMA CAR-T Cell Immunotherapy for Relapsed or Refractory Multiple Myeloma
CAR-T cell therapy has shown promising results for the treatment of relapsed or refractory Multiple Myeloma,however, a subset of patients relapse due to the loss of target in tumor cells.Dual Specificity CD38 and BCMA CAR-T cells…
- Trial name
- NCT03767751
- Testing
- Dual Specificity CD38 and bcma CAR-T Cells
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Genital Herpes
Serologic Assays for the Diagnosis of Herpes Simplex Virus Type 2
The purposes of this study are: To determine the accuracy of commercially available serologic assays in diagnosing patients with herpes simplex virus type 2 (HSV-2); To assess the sensitivity and specificity of the commerical…
- Trial name
- NCT01112956
- Where
- 3 sites in United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Asthma
Ability of Aridol to Detect Bronchial Hyperresponsiveness in Suspected Asthmatics
This is a Phase 3 study to determine the sensitivity and specificity of the Aridol bronchial challenge test to detect bronchial hyperresponsiveness in patients with suspected asthma.
- Trial name
- NCT00252291
- Testing
- Aridol, Methacholine, Exercise challenge
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Syntara
Child, Only, Narration
Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: the Hug the Child Study (HTC)
Background and study aims: The Eye Movement Desensitization and Reprocessing Group Protocol with Children (EMDR-GP/C) was first developed by Korkmazlar following the Marmara earthquake in Turkey in 1999 and can be adapted for…
- Conditions
- Child, Only, Narration, Memory Dysfunction, Distress, Emotional
- Trial name
- HTC (NCT05319002)
- Testing
- Group EMDR
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Pediatric Trauma Patients
Accuracy of Gastric POCUS in Pediatric Trauma
The goal of this observational study is to detect the predictive accuracy of the gastric POCUS in pediatric trauma patients undergoing urgent and semi urgent operative procedures.
- Trial name
- NCT06747403
- Volunteers
- 101 people
- Sponsor
- Assiut University
B Cell Leukemia, B Cell Lymphoma
A Feasibility and Safety Study of Universal Dual Specificity CD19 and CD20 or CD22 CAR-T Cell Immunotherapy for Relapsed or Refractory Leukemia and Lymphoma
CD19-directed CAR-T cell therapy has shown promising results for the treatment of relapsed or refractory B-cell malignancies; however, a subset of patients relapse due to the loss of CD19 in tumor cells.
- Trial name
- NCT03398967
- Testing
- Universal Dual Specificity CD19 and CD20 or CD22 CAR-T Cells
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Down Syndrome, Fragile X Syndrome
Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS)
To evaluate safety and tolerability of epigallocatechin gallate (EGCG) in children from 6 to 12 years old with Intellectual Developmental Disorders (IDD) (Down syndrome or Fragile X syndrome).
- Trial name
- PERSEUS (NCT03624556)
- Testing
- EGCG FontUp
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- Parc de Salut Mar
Epilepsy, Non-Epileptic Seizure
Validation of Criteria for Identification of Epileptiform Discharges in EEG Recordings of Patients With Epilepsy
Electroencephalography (EEG) records electric activity of the brain using electrodes placed on the scalp. EEG is an important tool in the diagnostic work-up of patients with epilepsy.
- Trial name
- CIED (NCT03533374)
- Testing
- Electroencephalogram (EEG) and visual evaluation
- Volunteers
- 100 people
- Sponsor
- Sándor Beniczky
Infection
ERNIE4: Urine and CRP Point-of-care Test in Acutely Ill Children
This study aims to assess the accuracy of a novel urine test for diagnosing urinary tract infections in acutely ill children presenting to ambulatory care.
- Trial name
- ERNIE4 (NCT03835104)
- Testing
- CRP point-of-care testing
- Where
- Belgium
- Volunteers
- 868 people
- Sponsor
- KU Leuven
Infectious Diseases
Specificity Study of Diagnostic for Chagas Disease
This study assesses the specificity of Chagas Detect™ Plus (CDP) rapid test versus standard reference tests (e.g. RIPA or IFA) for Chagas diagnosis in the US.
- Trial name
- NCT02544139
- Testing
- Chagas Detect Plus
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- InBios International, Inc.
Oral Potentially Malignant Lesions, Oral Cancer
Sensitivity and Specificity of Serum and Salivary CYFRA21-1 in the Detection of Malignant Transformation in Oral Potentially Malignant Mucosal Lesions (Diagnostic Accuracy Study)
The study is designed to measure serum and salivary CYFRA21-1 levels using enzyme linked immunosorbent assay (ELISA) in patients with oral malignancy, oral potentially malignant lesions, and control subjects to evaluate the…
- Trial name
- CYFRA21-1 (NCT03686020)
- Testing
- Enzyme Linked Immunosorbent assay (ELISA)
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neoplasia
The Sensitivity and Specificity of Sniff Dog as a Tool in Diagnosing the Suspected Tumor Patients
Previous studies have demonstrated that sniff dogs can identify cancer patients from healthy subjects through sniffing exhaled breath air or blood or serum or urine or feces.
- Trial name
- NCT02049658
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Chang-Qing Gao
Pneumonia, Pneumonia - Bacterial
Urine Pneumococcal Antigen Project
Background: Pneumonia caused by the bacteria Streptococcus pneumoniae is a leading cause of death among children under five years of age, especially in sub-Saharan Africa.
- Trial name
- UPAP (NCT07181200)
- Where
- Malawi
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Febrile Infection, Anthrax
Febrile Whole Blood Specimen Collection and Testing
Whole blood samples will be collected from febrile patients presenting with fever of unknown origin and flu-like syndromes. Collection sites will consent patients and collect one (1) 4 mL whole blood sample from adults and either…
- Trial name
- NCT03498027
- Testing
- TaqMan Bacillus anthracis Detection Kit
- Where
- 3 sites in United States
- Volunteers
- 97 people
- Sponsor
- MRI Global
SARS-CoV2 Infection, COVID-19
BinaxNOW for Evaluating Children for Infection With SARS-CoV-2 (COVID-19)
This is a study of the BinaxNOW Covid-19 Ag Card as a method to rapidly identify SARS-CoV-2 infection in asymptomatic children, teachers, and other school staff for exclusion.
- Trial name
- NCT05087524
- Testing
- BinaxNOW Ag Card
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Specific Positive Memories, Specific Positive Future Events
Recalling and Anticipating Specific Positive Events to Boost Resilience in Adolescents
Many young people are experiencing stress-related mental health problems, with some recent studies suggesting this number is increasing.
- Conditions
- Specific Positive Memories, Specific Positive Future Events, Resilience, Mental Wellbeing
- Trial name
- RASPERA (NCT05757180)
- Testing
- Positive Events Training (PET), CREAtive writing Training (CREAT)
- Where
- 5 sites in Belgium
- Volunteers
- 191 people
- Sponsor
- Prof. dr. Filip Raes
Peripheral Artery Disease
Exercise Testing in Peripheral Artery Disease Patients
The aim of this study was to evaluate exercise testing in case of patients suspected of Peripheral Artery Disease (PAD).
- Trial name
- ExercisePAD (NCT03186391)
- Testing
- Data collected
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Rennes University Hospital