Clinical trials: Speckle Tracking Echocardiography
Anorexia Nervosa, Obesity
Study of the Effects of Adolescent Weight Disorders (Obesity, Anorexia Nervosa) on Heart Function
The study aims to better understand the functioning of the heart of children and adolescents with anorexia nervosa or obesity, compared to the heart function of control subject.
- Trial name
- NCT05071157
- Testing
- echocardiography
- Where
- France
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Radiation Therapy
Early Detection of Cardiac Damage by Two-Dimensional Speckle Tracking Echocardiography After Thoracic Radiation Therapy
The purpose of this study is to detecte and predict early subclinical cardiac damage induced by thoracic radiation therapy based on two-dimensional speckle tracking echocardiography combined with multiple circulating biomarkers.
- Trial name
- NCT04443400
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Anterior MI, Colchicine
Effect of Colchicine On Left Ventricle Function After Anterior Myocardial Infarction Assessed By Speckle Tracking
Effect of colchicine use on Left ventricles systolic function in patients with anterior S-T elevation myocardial infarction undergoing primary Percutaneous coronary intervention by using speckle tracking Echocardiography…
- Trial name
- NCT05200052
- Testing
- Colchicine 0.5 mg Oral Tablet
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Left Ventricular Function, Arrhythmia
Impact of Radiofrequency Ablation on Left Ventricular Function in Supraventricular Tachyarrhythmias Patient Using Speckle Tracking Echocardiography
In this study, we aimed to evaluate atrial and ventricular function in supraventricular tachyarrhythmia patients before and 3 months after RFA using 2DSTE.
- Trial name
- NCT05225662
- Testing
- radiofrequency ablation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ischemic Heart Disease
Correlation Between Left Ventricular Global Strain Measured by Speckle Tracking Echocardiography and Scar Burden Measured by Cardiac Magnetic Resonance Imaging in Patients With Ischemic Heart Disease
To verify whether GLS and LV mechanical dispersion, measured by two-dimensional speckle-tracking echocardiography (2D-STE) correlate with LV scar burden measured by cardiac MRI in patients with ischemic heart disease.
- Trial name
- NCT04970017
- Testing
- Cardiac MRI, Echocardiography
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Assiut University
Left Ventricular Myocardial Dysfunction, End-Stage Kidney Disease
Assessment of Left Ventricular Myocardial Dysfunction in Children With End-Stage Kidney Disease Using Two-Dimensional and Three-Dimensional Speckle-Tracking Echocardiography
The present study aimed to assess left ventricular myocardial dysfunction in children with chronic kidney disease using 2D and 3D speckle-tracking echocardiography.
- Conditions
- Left Ventricular Myocardial Dysfunction, End-Stage Kidney Disease, Two-Dimensional Speckle-Tracking Echocardiography, Three-Dimensional Speckle-Tracking Echocardiography
- Trial name
- NCT07678710
- Testing
- Two-Dimensional Speckle-Tracking Echocardiography (2D-STE), Three-Dimensional Speckle-Tracking Echocardiography (3D-STE)
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Wilson's Disease, Myocardial Dysfunction
Subclinical Myocardial Dysfunction in Children With Wilson's Disease
Wilson's disease (WD) is one of the most common metabolic liver diseases in older children. The most frequent clinical presentation is liver disease. However, Wilson's disease (WD) is a multisystem disorder.
- Conditions
- Wilson's Disease, Myocardial Dysfunction, Children, Wilson Disease
- Trial name
- NCT07765472
- Testing
- Echocardiography, Electrocardiography, N-terminal pro b- type natriuretic peptide
- Where
- 2 sites in Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hebatullah Fawzy
Pheochromocytoma, Paraganglioma
Cardiac and Vascular Changes in Pheochromocytoma and Paraganglioma
PHEOCHROMOCYTOMA (PCC)/ PARAGANGLIOMA are catecholamine secreting tumors with varied manifestations. Besides hypertension, PCC patients may have subclinical to overt cardiac and vascular dysfunction, which are important to…
- Conditions
- Pheochromocytoma, Paraganglioma, Cardiovascular Morbidity
- Trial name
- PheoCard (NCT05082311)
- Testing
- Observational study
- Where
- India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Healthy Child
Echocardiographic Analysis in Healthy Child.
· 2D Speckle Tracking echocardiography gained importance for the evaluation of ventricle contractility. Many indications have been developed in child population.
- Trial name
- NCT02056925
- Testing
- Echocardiography
- Where
- France
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cardiotoxicity, Childhood Cancer
Prediction of Delayed Toxic Cardiomyopathy in Children
Longitudinal analysis of myocardial function using "Speckle Tracking Echocardiography" STE analysis and prediction of delayed toxic induced cardiomyopathy in young patients who received anthracycline therapy in childhood.
- Trial name
- SpeckleAnthra2 (NCT05781672)
- Testing
- cardiac ultrasound with speckle tracking analysis
- Where
- France
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Severe Obesity, Cardiovascular Function
Use of Liraglutide in Children Aged 6 to 12 Years With Severe Obesity
This randomized controlled trial evaluates the efficacy, safety, metabolic, and cardiovascular effects of liraglutide in children aged 6 to 12 years with severe obesity.
- Conditions
- Severe Obesity, Cardiovascular Function, Liraglutide, Childhood Obesity
- Trial name
- NCT07590219
- Testing
- Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Ebstein Anomaly
Assessment of Left and Right Ventricular Function in Patients With Ebstein Anomaly With Different Echocardiographic Methods
Ebstein anomaly is a rare congenital heart disease. It encompasses abnormalities of the tricuspid valve, the right atrium and the right ventricle (RV).
- Trial name
- NCT01907971
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- Angela Oxenius
Chronic Renal Disease, Chronic Renal Insufficiency
2D-speckle Tracking in Pediatric Renal Chronic Disease
The SPECKLE- KIDNEY-PED is a multicentre observational controlled trial aiming to evaluate the 2D-Speckle tracking in a population of 85 patients aged from 6 to 17 years old with a chronic renal disease and to compare the results…
- Conditions
- Chronic Renal Disease, Chronic Renal Insufficiency, Congenital Heart Disease
- Trial name
- SPECKLEKIDNEY (NCT04897672)
- Testing
- Observational study
- Where
- France
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Myocardial Function, Echographic Parameters Obtaind by Speckle Tracking
Study of Myocardial Function by Speckle Tracking After Cancer Treatment With Anthracyclines in Childhood
The main goal of this study is to compare the values of echocardiographic parameters obtained by Speckle Traking analysis on myocardial function among patients under 18 years treated with anthracyclines in childhood, with healthy…
- Conditions
- Myocardial Function, Echographic Parameters Obtaind by Speckle Tracking, Chilhood Cancers
- Trial name
- SPECKLEANTHRA (NCT02893787)
- Testing
- Speckle Tracking Echocardiography
- Where
- France
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cardio-oncology, Hematopoietic Stem Cell Transplantation
Early Identification and Evaluation of Cyclophosphamide Cardiotoxicity
Hematopoietic stem cell transplantation is an important method for the treatment of hematological diseases and cyclophosphamide is a commonly used chemotherapeutic agent for transplant pretreatment.
- Conditions
- Cardio-oncology, Hematopoietic Stem Cell Transplantation, Cardiotoxicity, Cyclophosphamide
- Trial name
- EIECC (NCT05150080)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Kai Mu
Duchenne Muscular Dystrophy
2D Strain Evaluation: Children With Duchenne Muscular Dystrophy Versus Healthy Children
Compare systolic function of left ventricle (LV) and right ventricle (VD) by 2D strain evaluation in Duchenne muscular dystrophy children versus a control group.
- Trial name
- NCT02418338
- Testing
- speckle tracking (2D strain) echocardiography
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Acute Myocardial Infarction
Intensive Statin Therapy in Patients With AMI
Objective: Statins have been shown to have beneficial pleiotropic effects besides being lipid lowering. The investigators hypothesized that early and intensive statin treatment was associated with improved left ventricular (LV)…
- Trial name
- INTENSIFY (NCT01923077)
- Testing
- Simvastatin, Rosuvastatin
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Svendborg Hospital
Premature Baby, Pulmonary Hypertension of Newborn
Measuring Heart Health in Both Term, Preterm and Unwell Newborn Babies With an Advanced Ultrasound Method: Speckle Tracking Echocardiography
This study aims to improve how neonatologists check the heart function of newborn babies, especially those who are sick. While standard heart ultrasound scans are useful, a more advanced and sensitive technique called 2D speckle…
- Conditions
- Premature Baby, Pulmonary Hypertension of Newborn, Hypoxic Ischaemic Encephalopathy (HIE), Congenital Diaphragmatic Hernia
- Trial name
- NCT07364682
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Healthy
Study by 2D-strain of the Ventricular Wall Motion During Postnatal Adaptation
The left ventricular torsion during systole and diastole is a normal dynamic mechanism which participates in the ejection and the filling of the left ventricle.
- Trial name
- BABYSTRAIN (NCT03654430)
- Testing
- Echocardiography
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Diastolic Dysfunction, Neonatal Encephalopathy
Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography
The goal of this single-centre longitudinal observational study is to create reference values for diastolic function parameters in neonates born at 35 weeks' gestation or above, and to assess the influence of pre-defined…
- Conditions
- Diastolic Dysfunction, Neonatal Encephalopathy, Small for Gestational Age at Delivery, Transient Tachypnea of the Newborn
- Trial name
- DiFuSE (NCT06200519)
- Where
- Ireland
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University College Cork