Clinical trials: Spectrum
Feeding Disorder, Autism Spectrum Disorder
The Effect Of Occupational Therapy On Sensory-Based Feeding Problems
Feeding problems are common in individuals with Autism Spectrum Disorder (ASD).This study was planned to investigate the effect of occupational theraphy on sensory feeding problems in ASD.
- Conditions
- Feeding Disorder, Autism Spectrum Disorder, Sensory Integration Disorder (Disorder)
- Trial name
- NCT03820869
- Testing
- Family Training, Occupational Therapy
- Volunteers
- 18 people
- Sponsor
- Hacettepe University
Psychosis
NAPLS Omega-3 Fatty Acid Versus Placebo Study
The overall goal of the present study is to determine whether Omega-3 Fatty Acids potentially prevent onset of psychosis and improve clinical symptoms and functional outcome in youth and young adults at elevated clinical risk for…
- Trial name
- NCT01429454
- Testing
- Omega-3 Long Chain Fatty Acid
- Where
- 9 sites in United States, Canada
- Volunteers
- 127 people
- Sponsor
- University of California, San Diego
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Brain Imaging in Babies Study
The aims of the BIBS Study The Brain Imaging in Babies study (BIBS) aims to improve understanding of how a baby's brain develops from before birth, up until 3-4 years of age.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Neurodevelopmental Conditions, COVID-19
- Trial name
- BIBS (NCT04443179)
- Where
- United Kingdom
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- King's College London
ADHD, Autism
Acceptability, Feasibility, and Development of an AI Driven, Multi-sensor, Non-invasive Digital Mental Health Platform in Children With ADHD and Emotional Symptoms
This is an observational study collecting data using a wearable to measure the biometric features in youth with Attention deficit hyperactivity disorder(ADHD) and Autism.
- Trial name
- NCT06311370
- Testing
- Observation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- MaxisHealth
First Episode Psychosis, Schizophrenia, Childhood
Early Psychosis Intervention - Spreading Evidence-based Treatment
Implementation of 'NAVIGATE' in Ontario aims to help youth and emerging adults suffering from a first episode of psychosis. Although Ontario already has early psychosis intervention programs, the team's recent work has identified…
- Conditions
- First Episode Psychosis, Schizophrenia, Childhood, Psychosis, Schizophrenia
- Trial name
- EPI-SET (NCT03919760)
- Testing
- NAVIGATE, Treatment as Usual
- Where
- 6 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Centre for Addiction and Mental Health
Autism Spectrum Disorder
Transcranial Photobiomodulation for Reducing Autism Symptoms in Children - Open Label Study (TPBMASDOL)
The hypothesis of the study is that photobiomodulation reduces symptoms of autism. Participants will be children between the ages of 2 and 7, who have been diagnosed with moderate to severe autism.
- Trial name
- NCT06359080
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- JelikaLite LLC
Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder
Neurogenetics and Multi-omics of Neuroinflammatory Diseases in Multiplex Families to Improve Patients Health
The goal of this observational study is to learn why some families have several members with multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), or MOG antibody-associated disease (MOGAD).
- Conditions
- Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, MOG Antibody-Associated Disease, Demyelinating Autoimmune Diseases, CNS
- Trial name
- NeuroDIP (NCT07902479)
- Testing
- Blood sampling and multi-omic profiling
- Where
- 5 sites in France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Schizophrenia, Schizophreniform Disorder
Integrated Care in Psychotic Disorders With Severe Mental Illness
The study examine the effectiveness of an integrated care program including therapeutic assertive community treatment (ACT) for people with psychotic disorders fulfilling severe and persistent mental illness (SPMI, ACCESS-II…
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, Delusional Disorder
- Trial name
- ACCESS-II (NCT01888627)
- Testing
- Integrated care
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Autism Spectrum Disorder
A Placebo-controlled Trial of Folinic Acid in Children With ASD
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by difficulties in social communication and the presence of restricted or repetitive behaviors.
- Trial name
- AFAT (NCT07642661)
- Testing
- Folinic Acid
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Prof. Adi Aran
PIK3CA-Related Overgrowth Spectrum (PROS), Growth Disorder
Study of Sirolimus Therapy for Segmental Overgrowth Caused by Somatic PI3K Activation
Background: PIK3CA-related overgrowth spectrum (PROS) is caused by changes in the PIK3CA gene. This gene makes a protein that communicates with other proteins in the body to cause cells to grow.
- Conditions
- PIK3CA-Related Overgrowth Spectrum (PROS), Growth Disorder, Genetics
- Trial name
- NCT02428296
- Testing
- Sirolimus
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Generalized Arterial Calcification in Infancy, Autosomal Recessive Hypophosphatemic Rickets Type 2
Understanding the Spectrum of ENPP1 Deficiency and Acute ABCC6 Deficiency
To date, the investigators lack characterization of, the burden of, and the systemic progression of disease in ENPP1 deficiency and ABCC6 deficiency from a patient and/or parent perspective.
- Trial name
- NCT04372446
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Inozyme Pharma
Autism Spectrum Disorder, Global Developmental Delay
Reliability and Validity of CCISO for Diagnosis of Autism Spectrum Disorder
The investigators designed the Child-Caregiver Interaction Observation Scale（CCIOS）to assess social communication behaviors, stereotyped behaviors for children with autism spectrum disorder(ASD) via a 20-min video of interactions…
- Conditions
- Autism Spectrum Disorder, Global Developmental Delay, Language Disorder
- Trial name
- NCT04511767
- Testing
- Do not take any interventions
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder
Active Ingredients & Efficacy of Aquatic Therapy for Autistic Children
Accidental drowning is the number one cause of death in children with autism spectrum disorders (ASD) and highlights the critical need for swim lessons and water safety training for this population.
- Trial name
- NCT05524753
- Testing
- AquOTic
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Febrile Neutropenia
Adjustment of Antibiotic Dosage in Pediatric Oncology Patients With Febrile Neutropenia and Augmented Renal Clearance
This clinical trial focuses on children with cancer who face infections after receiving chemotherapy. Chemotherapy affects the bone marrow, leading to a decrease in the production of certain white blood cells, particularly those…
- Trial name
- DAR-ARC (NCT06293677)
- Testing
- Dosage Adjustment Rules for Augmented Renal Clearance (DAR-ARC) for piperacillin-tazobactam and meropenem, Standard dosages of piperacillin-tazobactam or meropenem
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Autism Spectrum Disorders
Mirtazapine Treatment of Anxiety in Children and Adolescents With Pervasive Developmental Disorders
This study will determine the effectiveness of mirtazapine in reducing anxiety in children with autistic disorder, Asperger's disorder and Pervasive Developmental Disorder.
- Trial name
- NCT01302964
- Testing
- Mirtazapine
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Mind the Gap (AIR-B3)
There has been a lack of research on the unique needs of families with autism in the African-American and Latino communities. The process of screening, evaluation and treatment for children with autism can be long and arduous…
- Trial name
- MtG (NCT03711799)
- Testing
- Access to services via peer coaching
- Where
- 3 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Health Resources and Services Administration (HRSA)
Autism Spectrum Disorder, Intellectual Disability
Effectiveness of Music Therapy in Social Skill Intervention for Children With ASD/ID
Autism spectrum disorder (ASD) is a developmental impairment characterized by persistent deficits in social communication and interactions.
- Trial name
- NCT04557488
- Testing
- Music therapy, Behavioral-based social skill training
- Where
- Hong Kong
- Volunteers
- 77 people
- Sponsor
- Education University of Hong Kong
Autism Spectrum Disorder, Vestibular Hypofunction
Effect of Cawthorne Cooksey Exercises on Balance in Autistic Children With Vestibular Hypofunction.
The objective of the study is to determine the effects of cawthorne cooksey exercises on balance in autistic children with vestibular hypofunction.
- Trial name
- ASD (NCT07061119)
- Testing
- Conventional treatment, cawthorne cooksey exercises
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Equine-Assisted Therapy, Autism Spectrum Disorder
Equine Assisted Therapy in Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder that negatively affects social interaction, communication, and behavior. Various animals have started to be used for therapeutic purposes by those in need.
- Trial name
- AUTISM-EAT (NCT06057311)
- Testing
- Hippotherapy, Equine-Assisted Activities Therapy, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Izmir Democracy University
Autism Spectrum Disorder
The Efficacy of EMDR in Youngsters With Autism
Rationale: Currently, for youngsters there is no treatment available that directly targets the core symptoms of autism. EMDR is hypothesized to improve the core symptoms of ASD by reducing the generally high stress levels…
- Trial name
- EYE-catcher (NCT03467464)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR)
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Karakter Kinder- en Jeugdpsychiatrie
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