Clinical trials: Spectrum
Schizophrenia, Schizoaffective Disorder
Schizophrenic Patients in Integrated Care
The purpose of the study is to investigate the well-being of schizophrenic patients treated with quetiapine XR combined with participation in the integrated care program compared to a treatment with quetiapine XR alone over a…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- CARE II (NCT00681629)
- Testing
- Quetiapine XR, Integrated Care Program (ICP)
- Where
- 8 sites in Germany
- Volunteers
- 7 people
- Sponsor
- AstraZeneca
Macular Holes
Foveal Cone Outer Segment Resumption to Predict Visual Recovery After Macular Hole Surgery
Spectral domain optical coherence tomography (SD-OCT) was used to determine whether the repair of photoreceptor cone outer segment tips defect is significantly correlated with the visual outcomes after macular hole surgery.
- Trial name
- NCT01381965
- Testing
- Vitreous surgery for macular hole
- Where
- Japan
- Volunteers
- 72 people
- Sponsor
- Kyorin University
Schizophrenia, Psychosis
To Rescue Cognition With Valaciclovir
This is a one-week, randomized, double blind add-on study of valaciclovir versus placebo in 24 clinical patients with Schizophrenia according to DSM IV, currently experiencing psychosis as is defined by the positive items of the…
- Trial name
- NCT01364792
- Testing
- Valaciclovir
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- University Medical Center Groningen
Schizophrenia
Amisulpride in Schizophrenic Acute Phase Patients
To collect the safety and response of using Amisulpride in acute schizophrenic patients
- Trial name
- ASAP (NCT00436371)
- Testing
- Amisulpride
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Sanofi
Transcranial Direct Current Stimulation, Autistic Spectrum Disorder
Cumulative and Booster Effects of Multisession Prefrontal Transcranial Direct Current Stimulation in Adolescents With ASD
Autism spectrum disorder (ASD) is a pervasive and lifelong developmental disorder that currently affects 1 in 54 children. Individuals with autism are often severely impaired in communication, social skills, and cognitive…
- Conditions
- Transcranial Direct Current Stimulation, Autistic Spectrum Disorder, Electroencephalography, Booster Effects
- Trial name
- NCT05492032
- Testing
- Active-tDCS, Cognitive training
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The Hong Kong Polytechnic University
Schizophrenia
Enhancing Motivation in Recent Onset Schizophrenia
This project will result in the development of a personalized intervention strategy to improve motivation for treatment engagement and functional outcomes in individuals with a recent onset of schizophrenia.
- Trial name
- PRIME (NCT01817387)
- Testing
- PRIME, Cognitive Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Schizophrenia
A Bioequivalence Study of 15 mg ER OROS Paliperidone
The purpose of this study is to evaluate the bioequivalence between the Phase 3 and the to-be-marketed formulations of extended release (ER) OROS paliperidone and to evaluate the effect of food on the highest to be marketed…
- Trial name
- NCT00892489
- Testing
- ER OROS Paliperidone
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Bipolar Spectrum Disorder
Open-Label Comparative Study of Risperidone Versus Olanzapine Versus Quetiapine for Mania in Children and Adolescents With Bipolar I and Bipolar II Disorder
The objective of this study is to compare the safety and effectiveness of Risperidone, Olanzapine, and Quetiapine in the treatment of mania in children and adolescents with Bipolar disorder over 8 weeks and then over an extension…
- Trial name
- NCT00182013
- Testing
- Risperidone, Olanzapine, Quetiapine
- Volunteers
- 106 people
- Sponsor
- Massachusetts General Hospital
Autism, Autistic Disorder
Use of Acupuncture In Children With Autistic Spectrum Disorder
This is a study of the efficacy of acupuncture in children with autism.
- Trial name
- NCT00352352
- Testing
- Tongue Acupuncture (Procedure)
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
Schizophrenia
Validation of a Clinical Screening Grid for Syndromic Schizophrenia
Background: Nowadays, despite a large number of studies about schizophrenia and genetics, clinical red flags for syndromic forms of schizophrenia remain poorly documented.
- Trial name
- Schizo-CGH-EXM (NCT02746510)
- Testing
- Array comparative genomic hybridization
- Where
- France
- Volunteers
- 129 people
- Sponsor
- Hôpital le Vinatier
Schizophrenia, Schizoaffective Disorder
Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study
The purpose of this study is to get a better understanding of the side effect burden and identify predictors of psychotic, mood and aggressive disorders in children and adolescents.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Psychotic Disorder, Not Otherwise Specified
- Trial name
- SATIETY (NCT01269710)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of North Carolina, Chapel Hill
Psychosis of Childhood Borderline, Psychotic Disorder
Study of Self-Recognition and Self/Other Distinction Disorders in Patients With Psychological Vulnerability
The main objective of this study is to establish whether there are differences in self-recognition and self/other distinction in subjects with psychological vulnerability compared to healthy volunteer controls.
- Trial name
- ALTER-EGO (NCT04945278)
- Testing
- Double mirror device ALTER-EGO, EASE test
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Depression, Anxiety
Participatory Messaging in the UCLA Psychiatry Partial Hospitalization and Intensive Outpatient Programs
This research project aims to evaluate the feasibility and effectiveness of a new approach to tailored mobile applications using the Chorus Participatory Mobile Framework.
- Conditions
- Depression, Anxiety, Psychosis
- Trial name
- NCT02708940
- Testing
- Participatory technology development, Usual Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles
Schizophrenia
rTMS for Auditory Hallucinations Guided by Magnetoencephalography
rTMS and MEG for auditory hallucinations via self controlled clinical trials. Repetitive transcranial magnetic stimulation (rTMS) can increase or decrease cortical excitability in patients with psychosis (such as schizophrenia).
- Trial name
- NCT05598450
- Testing
- rTMS and MEG for auditory hallucinations via self controlled clinical trials
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Mental Health Center
Schizophrenia
A Study to Assess Safety and Efficacy of KarXT in Adult Patients With Schizophrenia
This is a Phase 2, randomized, double-blinded, placebo-controlled, inpatient study to examine the efficacy, safety, and tolerability profile of KarXT in adult subjects diagnosed with DSM-5 schizophrenia who are in an acute…
- Trial name
- EMERGENT-1 (NCT03697252)
- Testing
- Xanomeline and Trospium Chloride Capsules
- Where
- 12 sites in United States
- Volunteers
- 182 people
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Autism
Open Label of Clinical Trial of Sulforaphane in Children With Autism
This is an open-label, 4-month study examining the effects of Sulforaphane (SF) on behavior in children with ASD and the correlation between behavior change and urinary metabolites.
- Trial name
- NCT02654743
- Testing
- Sulforaphane
- Volunteers
- 21 people
- Sponsor
- University of California, San Francisco
Schizophrenia and Related Disorders, Psychotic Disorders
Exercise and Overnight Motor Sequence Task
The objective of this randomized controlled trial (RCT) is to compare the changes of the sleep-related memory functions in patients with psychosis after they have completed the 12-week high-intensity exercise intervention, the…
- Trial name
- EOMST (NCT03800368)
- Testing
- Exercise, Non-exercise
- Volunteers
- 51 people
- Sponsor
- The University of Hong Kong
Placenta Accreta, Third Trimester, Uterine Scar Dehiscence
Ultrasound Model to Help Differentiate Between Placenta Accreta Spectrum and Uterine Dehiscence in 3rd Trimester Pregnancies
By using 2d Ultrasound on 3rd trimester pregnant women, a model is made to help differentiate between placenta accreta spectrum and uterine scar dehiscence before operative action to help prepare multi-disciplinary steps if needed
- Trial name
- NCT07236060
- Testing
- 2D ultrasound doppler
- Volunteers
- 50 people
- Sponsor
- Assiut University
Schizophrenia
Treatment of Patients With Recently Exacerbated Schizophrenia With Paliperidone Palmitate
The purpose of this study is to explore the efficacy of paliperidone palmitate administered as a once monthly injection in patients with an acute exacerbation of schizophrenia.
- Trial name
- NCT01448720
- Testing
- Paliperidone palmitate
- Where
- 12 sites in Brazil, Colombia and 1 more
- Volunteers
- 142 people
- Sponsor
- Janssen-Cilag Farmaceutica Ltda.
Toxoplasmosis, Schizophrenia
Pilot Trial of Valproate as Adjunctive Treatment for Toxoplasma Gondii Infection in Early Course Schizophrenia
This is an exploratory study in Egypt that will combine a treatment trial among early course schizophrenia (ECSZ) patients with key analyses suggested by rodent studies.
- Trial name
- NCT02011750
- Testing
- Sodium Valproate treatment
- Where
- Egypt
- Volunteers
- 109 people
- Sponsor
- University of Pittsburgh
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