Clinical trials: Spectrum
Cerebral Palsy, Developmental Coordination Disorder
Bootle Blast: Understanding the Family Experience
One in 60 children have a physical disability that can impact activities and participation. Occupational and physical therapies can be of great benefit, but are costly and difficult to access.
- Conditions
- Cerebral Palsy, Developmental Coordination Disorder, Developmental Disability, Autism Spectrum Disorder
- Trial name
- NCT06161168
- Testing
- Bootle Blast Play Phase (B)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Intellectual Disability
Research and Characterization of New Genes Involved in Intellectual Disability
Intellectual disability (ID) occurs in 2 to 3 % of the general population but the cause is identified only in 30 to 60% of cases.
- Trial name
- GeneDefi (NCT01867554)
- Testing
- gene analysis
- Where
- France
- Volunteers
- 8,500 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Autism Spectrum Disorder, Social Communication Disorder
Virtual Group Social ABCs - Multi-site Randomized Controlled Trial
The goal of this randomized control trial is to test the efficacy of the Social ABCs 6 week, group-based model using a virtual delivery platform.
- Conditions
- Autism Spectrum Disorder, Social Communication Disorder, Autism or Autistic Traits, Autism Spectrum Disorder With Impaired Functional Language
- Trial name
- NCT05663970
- Testing
- VG Social ABCs
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Fatty Acid Supplementation in Children With ASD (Study 2)
The objective of the protocol is to test the impact of Omega 3-6 on pre-specified biological signatures (IL-1β, IL-2, and IFNγ) and to correlate changes in the biological signatures with changes in ASD symptoms.
- Trial name
- NCT04312932
- Testing
- LCPUFA Oil Supplement
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Sarah Keim
Mood Disorders, Psychotic Disorders
Family-Focused Therapy for Youth With Early-Onset Bipolar or Psychotic Disorders
The present study aims to : 1. compare different approaches (high intensity vs. low intensity) to training community providers (those who routinely treat young patients with bipolar disorder, psychosis, or sub-threshold high-risk…
- Trial name
- FFT (NCT02097563)
- Testing
- High Intensity Training, Low Intensity Training
- Where
- 3 sites in United States
- Volunteers
- 133 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Culturally Adapted Play-Based Behavioural Intervention for Autism
This study compared Culturally Adapted Play-Based Behavioural Intervention (PPBI) and Applied Behaviour Analysis (ABA) for children with Autism Spectrum Disorder (ASD) in semi-rural Tamil Nadu through a double-blinded randomized…
- Trial name
- NCT06859541
- Testing
- Culturally Adapted Play-Based Behavioural Intervention, Applied Behaviour Analysis
- Where
- India
- Volunteers
- 56 people
- Sponsor
- Saveetha University
Autism
Examining the Effects of Group Versus Individual Based Exercise Program on Balance and Coordination in Children With Autism
This study compared the effects of group-based versus individual-based exercise programs on balance and coordination in children aged 3-12 years who were diagnosed with Autism Spectrum Disorder (ASD) Level 1.
- Trial name
- NCT07799051
- Testing
- Individual based, Group Based Exercise
- Where
- Pakistan
- Volunteers
- 16 people
- Sponsor
- Ibadat International University, Islamabad
PIK3CA-Related Overgrowth Spectrum (PROS)/Proteus Syndrome (PS)
A Study of the Safety and Tolerability in Participants With PIK3CA-related Overgrowth Spectrum or Proteus Syndrome Who Are Being Treated With Miransertib (MK-7075) in Other Studies (MK-7075-006)
This is a study of the safety and tolerability of oral miransertib (MK-7075) administered to participants at least 2 years of age with phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA)-related…
- Trial name
- NCT04980872
- Testing
- Miransertib
- Where
- 11 sites in United States, Australia and 3 more
- Volunteers
- 60 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes, Hypertension
Pharmacy Interventions to Improve Chronic Disease Medication Refill
Compare the effectiveness of 3 strategies by pharmacists to decrease the time to refill of prescriptions for common chronic diseases (diabetes, hypertension, hyperlipidemia, heart failure, depression, psychoses).
- Conditions
- Diabetes, Hypertension, Hyperlipidemia, Heart Diseases
- Trial name
- NCT00469365
- Testing
- pharmacist contact with the patient via telephone, Pharmacist contact with the patient's physician via fax, Usual care
- Where
- United States
- Volunteers
- 3,048 people
- Sponsor
- Medical University of South Carolina
Aplastic Anemia
Oral Manifestations of Aplastic Anemia
The purposes of this study are threefold: 1) to evaluate the prevalence and risks of oral complications in patients with aplastic anemia; 2) to evaluate if oral problems in these patients can predict their response to treatment…
- Trial name
- NCT00006300
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Autism Spectrum Disorder, Autism
Treatment Monitoring in Autism Spectrum Disorder (ASD) in Children
The goal of this clinical study is to learn about the utility and performance of the EarliPoint(™) System: Evaluation for Autism Spectrum Disorder to monitor changes in a child's verbal ability, non-verbal learning, and social…
- Conditions
- Autism Spectrum Disorder, Autism, Developmental Delay, Autism, Early Infantile
- Trial name
- MEASURE-ASD1 (NCT05675371)
- Testing
- Assessment by Expert Clinician During Behavioral Intervention (ABA or similar), Assessment by the EarliPoint Assessment For Autism Spectrum Disorder
- Where
- 9 sites in United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- EarliTec Diagnostics, Inc
Autism Spectrum Disorders
Parents Workgroup About Emotion Regulation
The purpose of this study is examine emotional regulation and reflective functioning in parents of children with Autism Spectrum Disorders (ASD) before and after an educational training (four sessions of group workshops).
- Trial name
- NCT02400177
- Testing
- emotion regulation training
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Stanford University
Schizophrenia, Psychotic Disorders
Enhancing the Prospective Prediction of Psychosis
This study will gather information on the natural history of the basic symptoms of psychosis to identify factors that may affect the improvement or persistence of the symptoms.
- Trial name
- NCT00291200
- Where
- 3 sites in United States, Canada
- Volunteers
- 268 people
- Sponsor
- Yale University
Autism Spectrum Disorder
Family Centered Occupational Therapy on Play Skills and Participation of Children With ASD
Play skills and participation of children with Autism Spectrum Disorder (ASD) have been restricted by their core symptoms, resulting in heightened parenting stress and affected family daily life.
- Trial name
- NCT02795611
- Testing
- Family-centered occupational therapy, regular occupational therapy, intervention done outside our hospital
- Where
- Taiwan
- Volunteers
- 23 people
- Sponsor
- National Taiwan University Hospital
Autism, Pervasive Development Disorder
Atomoxetine, Placebo and Parent Management Training in Autism
The study will evaluate the effectiveness of atomoxetine (Strattera) with and without Parent Management Training (PMT) in children with Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified…
- Conditions
- Autism, Pervasive Development Disorder, Asperger's Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- Strattera (NCT00844753)
- Testing
- atomoxetine, Parent Management Training
- Where
- 3 sites in United States
- Volunteers
- 128 people
- Sponsor
- University of Rochester
ASD
Internal Versus External Attentional Focus in Gross- and Fine-Motor Learning Among Children With Autism Requiring Ongoing Everyday Support
This study examined how different attentional focus instructions affect motor learning in children with autism spectrum disorder (ASD).
- Trial name
- NCT07851272
- Testing
- External Focus of Attention Instructions, Internal Focus of Attention Instructions
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- University of Haifa
PIK3CA-Related Overgrowth Spectrum (PROS), Breast Cancer
Managed Access Programs for BYL719, Alpelisib
The purpose of this registration is to list Managed Access Programs (MAPs) related to BYL719, Alpelisib
- Trial name
- NCT04085653
- Testing
- alpelisib
- Sponsor
- Novartis Pharmaceuticals
Autism Spectrum Disorder, Somatic Symptom Disorder
Somatic Symptoms in Autism Spectrum Disorder: Data Integration
Autistic patients have higher rates of co-morbid somatic symptoms. Thus, compared to the general population, they experience more health-related concerns, such as autoimmune disease, gastrointestinal disease, cardiovascular…
- Trial name
- NCT05886361
- Testing
- No intervention involved
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Psychiatric Disorders, Neurodevelopmental Disorders
CYP2D6 Pharmacogenetics in Risperidone-Treated Children
Risperidone is an important medication used to treat children with psychiatric illnesses or neurodevelopmental disorders, such as autism. Despite excellent symptom control, the potential for side effects is worrisome.
- Trial name
- NCT00783783
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Literacy, Communication, Nonverbal
Enhancing Orthographic Communication and Literacy Outcomes for AAC Learners
The goal of this clinical trial is to determine whether adding Integrated Decoding and Encoding instruction to the ALLSTAR literacy program improves reading outcomes for students with significant literacy and communication needs.
- Trial name
- NCT07384156
- Testing
- ALLSTAR
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Penn State University
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