Clinical trials: Spectrum
Autism Spectrum Disorder
A Deep Learning Algorithm Platform to Predict Autism Diagnosis and Subtypes
This is the first human study on ASD microbiome with robust methodologies: prospective and sibling designs, metagenomics profiles, establishing an ASD multi-dimensional databank (clinic, behavior, neurocognition, brain imaging…
- Trial name
- NCT04873674
- Testing
- ASD diagnosis, Psychiatric diagnosis
- Where
- Taiwan
- Volunteers
- 420 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
A Protocol to Streamline Dental Care in Autistic Children
The investigators aim at creating a dedicated pathway to allow accessibility to dental care for ASD children within a hospital Dentistry Department, in order to diminish the need for general anesthesia.
- Trial name
- DentAutism (NCT05553262)
- Testing
- Behavioral support
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- University of Padova
Autism Spectrum Disorder
Early Intervention and Autism: Transformation From Research to Practice Through a Competency Based Model
This study evaluates the effect of a competency based model on program quality in Swedish preschools for Children with autism spectrum disorder (ASD).
- Trial name
- AUT-TID (NCT03634761)
- Testing
- Competency based model, Comprehensive program
- Where
- 2 sites in Sweden
- Volunteers
- 17 people
- Sponsor
- Stockholm University
Autism Spectrum Disorder
Cerebellar tDCS in Children With Autism Spectrum Disorder
The purpose of this research study is to investigate whether tDCS to the cerebellum (specifically, the right crus I/II area of the cerebellum) of children and young adults with autism spectrum disorders (ASD) is safe and to…
- Trial name
- NCT04446442
- Testing
- tDCS
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Autism or Autistic Traits
Clinical Cohort Study of DHA in Neurodevelopmental Disorders
Neurodevelopmental disorders are a group of developmental disorders, including autism spectrum disorders (ASDs), attention deficit hyperactivity disorder (ADHD) and others, that begin at a developmental stage and severely affect…
- Trial name
- NCT05841927
- Testing
- Docosahexaenoic acid supplement
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Fudan University
Neurodevelopmental Disorders, Autism Spectrum Disorder
Patterns of Neurodevelopmental Disorders
The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection, Pediatric Acute-Onset Neuropsychiatric Syndrome
- Trial name
- NCT06213090
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Richard Frye
First Episode Psychosis, Schizophrenia, Childhood
Early Psychosis Intervention - Spreading Evidence-based Treatment
Implementation of 'NAVIGATE' in Ontario aims to help youth and emerging adults suffering from a first episode of psychosis. Although Ontario already has early psychosis intervention programs, the team's recent work has identified…
- Conditions
- First Episode Psychosis, Schizophrenia, Childhood, Psychosis, Schizophrenia
- Trial name
- EPI-SET (NCT03919760)
- Testing
- NAVIGATE, Treatment as Usual
- Where
- 6 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Centre for Addiction and Mental Health
Autism Spectrum Disorder
A Trial of Project ImPACT in Early Intervention
Our pilot study will address a number of pressing questions, including: Can community clinicians successfully coach parents of children with ASD in evidence-based practice to achieve positive outcomes for their children and…
- Trial name
- NCT04729127
- Testing
- Project ImPACT
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Pennsylvania
First Episode Psychosis, Schizophrenia
OnTrackNY With the Option of Social Network Meetings
Early intervention programs for psychosis help improve short-term treatment and recovery outcomes for individuals experiencing psychosis.
- Trial name
- NCT03464162
- Testing
- Social Network Meetings
- Where
- United States
- Sponsor
- Lisa Dixon
Cannabis-Related Disorder, Substance-Related Disorders
First Episode Schizophrenia and Cannabis-Related Disorder Study
Many individuals with schizophrenia abuse cannabis at the onset of their illness, portending a poorer course of illness and poorer treatment response.
- Conditions
- Cannabis-Related Disorder, Substance-Related Disorders, Schizophrenia, Psychotic Disorders
- Trial name
- NCT00573287
- Testing
- clozapine, risperidone
- Where
- 5 sites in United States
- Volunteers
- 14 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Psychosis
Tolerance and Effect of Antipsychotics in Children and Adolescents With Psychosis
The benefits and harms of antipsychotics are relatively well studied in adults. However, there is a lack of scientifically valid studies regarding the benefits and harms of antipsychotics in children and adolescents with…
- Trial name
- TEA (NCT01119014)
- Testing
- Aripiprazole, Quetiapine
- Where
- 9 sites in Denmark
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Anne Katrine Pagsberg
Autistic Disorder
A Controlled Study of Olanzapine in Children With Autism
This is a 12-week study which investigates the use of olanzapine to decrease disruptive behaviors sometimes associated with Autism in children, aged 3 to 12 years old.
- Trial name
- NCT00057408
- Testing
- olanzapine (Zyprexa)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- FDA Office of Orphan Products Development
Psychosis, Schizophrenia
Study of Language Disorders and Interactions Between Mnesic Capabilities and Semantic Competencies in Patients With Psychosis
This research concerns the study of language disorders of patients present in the spectrum of psychosis. It is indeed accepted that psychotic disorders are associated with language difficulties, which are only poorly highlighted…
- Conditions
- Psychosis, Schizophrenia, At-risk Mental State, Language Disorders
- Trial name
- TDLRipsy (NCT06036316)
- Testing
- Language assessment, TLC - Scale for the Assessment of Thought, Language, and Communication, MINI - Mini International Neuropsychiatric Interview
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Psychothérapique de Nancy
Psychotic Disorders
Impact of Case-management on Therapeutic Alliance With First Episode Psychosis Patients (CAMAT)
The first aim of this study is to test the effect of the case management on the evolution of therapeutic alliance in patients with first episode psychosis in comparison with traditional nursing.
- Trial name
- CAMAT (NCT02873884)
- Testing
- Case-management
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Multiple Myeloma, Hematologic Diseases
Multiple Myeloma Prognostic Indices
The aim of this study was to evaluate the impact of albumin / fibrinogen ratio, blood viscosity and RDW on the prognosis of a newly diagnosed MM patients
- Trial name
- NCT06095752
- Testing
- blood viscosity , albumin / fibrinogen ratio and red cell distribution
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
Psychosis
A Study of the Effectiveness of Cognitive Adaptation Training in Early Intervention for Psychosis
The proposed study will involve a randomized trial of Cognitive Adaptation Training (CAT) for early intervention as compared against an active control in which Action Based Cognitive Remediation (ABCR) will be applied.
- Trial name
- NCT02430935
- Testing
- Cognitive Adaptation Training, Action Based Cognitive Remediation
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- Centre for Addiction and Mental Health
Autism Spectrum Disorder
Telehealth Intervention for Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is one of the most frequently occurring childhood-onset neurodevelopmental disorders affecting 1 in every 54 children.
- Trial name
- NCT04832152
- Testing
- OT4ASD
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Autism Spectrum Disorders
Single Dose Double-blind, Placebo-controlled Cross-over (SDDBPCCO) Shiftability Study, Will be Followed by a 10-week Open-label Study With Arbaclofen (4 Weeks of Titration and Then 6 Weeks of Active/Stable Treatment). The Effects of Arbaclofen on Target EEG and ERG Metrics Will be Associated With th
study with arbaclofen (4 weeks of titration and then 6 weeks of active/stable treatment). The effects of arbaclofen on target EEG and ERG metrics will be associated with the clinical response in measures of social and general…
- Trial name
- NCT07655115
- Testing
- Arbaclofen
- Where
- 5 sites in France, Spain
- Volunteers
- 103 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Smith-Magenis Syndrome, Autism Spectrum Disorder
Smith Magenis Syndrome and Autism Spectrum Disorders
Autism Spectrum Disorders (ASD) are a neurodevelopmental disorder. Their prevalence is estimated at around 0.4% of the general population worldwide.
- Trial name
- SMS/TSA (NCT05116904)
- Testing
- Assessment
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
ADHD, Autism
Trial to Assess the Pharmacokinetics, Safety, Tolerability of Oral Brexpiprazole in Children (6 to <13 Years Old) With Central Nervous System Disorders
A study to assess pharmacokinetics, safety and tolerability of brexpiprazole in children ages 6 to <13 years with CNS disorders.
- Conditions
- ADHD, Autism, Bipolar I Disorder, Conduct Disorder
- Trial name
- NCT03292848
- Testing
- Brexpiprazole
- Where
- 9 sites in United States
- Volunteers
- 24 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
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