Clinical trials: Spectrum
Autism Spectrum Disorder, Children
Sensory Integration Therapy in a Sample of Children With Autism Spectrum Disorder
The objective of this study is to determine the effects of therapy in sensory rooms with multisensory environment on the severity of autism spectrum disorder and stereotyped and repetitive behaviours in a sample of Egyptian…
- Conditions
- Autism Spectrum Disorder, Children, Therapy
- Trial name
- NCT06882642
- Testing
- Sensory integration therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity
Where Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and Youth
The goal of this action research project is to develop and implement nature- and activity-based group interventions across health care, school and leisure settings in Southern Norway.
- Conditions
- Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity, Autism, Tourette Syndrome
- Trial name
- NCT07203469
- Testing
- Universal approach, Selective approach, Outdoor therapy
- Where
- 2 sites in Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Psychosis, Medication Adherence
Piloting MOL Intervention for Neuroleptic Decision Making
The aim of the current study is to pilot a novel intervention to help people explore their decision making around the use of neuroleptic medication.
- Trial name
- NCT03537040
- Testing
- Method of Levels
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Manchester
Autistic Disorder
Diffusion Tensor Imaging in Autism
Using a new and more detailed approach to diffusion tensor imaging (DTI) recently developed in our lab, the investigators hope to learn more about irregularities in the brain that are related to autism.
- Trial name
- NCT00382382
- Testing
- diffusion tensor imaging (DTI)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Autism
Parent-delivered Massage for Children With Autism
Through funding from the U.S. Maternal and Child Health Bureau, Teaching Research Institute at Western Oregon University (WOU) will be conducting research on the effect of a parent-delivered massage program on measures of autism…
- Trial name
- NCT01801696
- Testing
- Parent massage tx group, Parent massage wait-list control group
- Where
- 4 sites in United States
- Volunteers
- 103 people
- Sponsor
- Western Oregon University
Bipolar Disorder, Mania
Aripiprazole for the Treatment of Mania in Children and Adolescents With Bipolar Disorder
This is an open-labeled study of Aripiprazole, testing its efficacy in the treatment of mania in children and adolescents with Bipolar I, Bipolar II and Bipolar Spectrum Disorder over 8 weeks.
- Trial name
- NCT00181779
- Testing
- aripiprazole (Abilify)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Status Epilepticus, Ictal-interictal Continuum
The Role of Imaging in the Diagnosis, Management and Prognosis of Possible Non-convulsive Status Epilepticus
The investigators propose a prospective study of 20 control subjects and 180 consecutive patients with possible non-convulsive status epilepticus (NCSE). The investigators will obtain three functional images of the brain: 1.
- Conditions
- Status Epilepticus, Ictal-interictal Continuum, Positron-emission Tomography, Perfusion Weighted MRI
- Trial name
- NCT06017973
- Testing
- MRI scan including arterial spin labelling of the brain, CT perfusion scan of the brain, FDG-PET scan of the brain
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Autistic Disorder
e-Unstuck:Interactive e-Learning Software for Parents to Support Executive Functioning and Behavior Regulation in Children With Autism Spectrum Disorder
The goal of this project is to develop and test e-Unstuck, an e-learning intervention that (1) provides advanced training to parents of children with Autism Spectrum Disorder without Intellectual Disability (ASDwoID) on how to…
- Trial name
- e-Unstuck (NCT02708069)
- Testing
- e-Unstuck, Unstuck and On Target
- Where
- 2 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- 3-C Institute for Social Development
Weight Gain, Autism Spectrum Disorder
Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole
This study aims to compare two FDA approved medications (aripiprazole and risperidone) for the treatment of behavioral dysregulation in children with autism spectrum disorders.
- Conditions
- Weight Gain, Autism Spectrum Disorder, Medication Side Effect
- Trial name
- NCT04903353
- Testing
- Comparison of Risperidone and Aripiprazole
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Schizophrenia
Novel Candidate Genes for Treatment Response to Antipsychotics in Schizophrenia
Schizophrenia is a severe and chronic mental disorder. The lifetime risk of schizophrenia is around 1%. Its course is chronic and frequently disabling. The keystone of schizophrenia treatment is antipsychotic medications.
- Trial name
- GEXANT (NCT02205437)
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundación Marques de Valdecilla
Autism, Autism Spectrum Disorder
Urinary Steroid Metabolites in Autism
Deviation of hormone formation within nerve cells and nerve system provides autism spectrum disorder and neurodevelopment retardation through interaction of steroids with neurotransmitter-receptors, calcium-channel receptors and…
- Trial name
- NCT01197131
- Where
- Austria
- Volunteers
- 160 people
- Sponsor
- Intersci Research Association, Austria
Autism, Sleep Disturbances in Children
Differences in Rest, Emotion, and Arousal Modulation in Youth
The goal of this study is to examine the relationship between sensory responsivity, bedtime arousal levels, sleep disturbances, and daytime emotion dysregulation for autistic children (ages 6-10).
- Conditions
- Autism, Sleep Disturbances in Children, Sleep
- Trial name
- DREAMY-Autism (NCT07476937)
- Testing
- Power Down bedtime manipulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder
Culturally Adapted Play-Based Behavioural Intervention for Autism
This study compared Culturally Adapted Play-Based Behavioural Intervention (PPBI) and Applied Behaviour Analysis (ABA) for children with Autism Spectrum Disorder (ASD) in semi-rural Tamil Nadu through a double-blinded randomized…
- Trial name
- NCT06859541
- Testing
- Culturally Adapted Play-Based Behavioural Intervention, Applied Behaviour Analysis
- Where
- India
- Volunteers
- 56 people
- Sponsor
- Saveetha University
Autism Spectrum Disorder
Therapeutic Issues for Autism
This study aimed to show the effects of hyperbaric oxygen therapy and/or Risperidone in improving symptoms of autism
- Trial name
- NCT03887754
- Testing
- Risperidone, hyperbaric oxygen therapy, Non specific Multivitamin
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Minia University
Autism Spectrum Disorder, Neurodevelopmental Disorders
A Smart Toy for Motor Function and Early Assessment of Children With Possible Autism
Autism diagnostic referrals across the UK have doubled within the last five years. Covid-19 has further delayed diagnostic pathways, while innovation has not kept pace in assisting clinical teams with low cost, fast, and…
- Trial name
- Tangiball (NCT04980677)
- Testing
- Tangiball
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Sussex Community NHS Foundation Trust
Cutaneous Lymphoproliferative Diseases, Mycosis Fungoides of Skin (Diagnosis)
Development of an AI-Assisted Diagnostic Tool for Mycosis Fungoides and Other Cutaneous Lymphoproliferative Diseases Using Microscopic Image Analysis: A Training and Validation Study
Cutaneous lymphoproliferative diseases (CLPDs) are a group of skin disorders that range from benign conditions, such as pseudolymphomas, to malignant forms like cutaneous T-cell and B-cell lymphomas.
- Conditions
- Cutaneous Lymphoproliferative Diseases, Mycosis Fungoides of Skin (Diagnosis), T Cell Dyscrasia, PLEVA-PLC Spectrum
- Trial name
- NCT07705386
- Testing
- AI-assisted histopathology image analysis
- Where
- Egypt
- Volunteers
- 463 people
- Sponsor
- Cairo University
Autism Spectrum Disorder
Integrated Platform for Measuring and Reducing Symptoms of Autism Spectrum Disorder
This study will consist of a randomized, double-blind, sham-controlled clinical trial at SUNY Upstate Medical University and Mt.
- Trial name
- IPMR ASD (NCT06006637)
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- State University of New York - Upstate Medical University
Autism Spectrum Disorder, Intellectual Disability
Vagus Nerve Stimulator for Autism and Other Developmental Disorders
The goal of this flexible single-subject design vagus nerve stimulation (VNS) study is to examine the behavioral, cognitive, and biorhythmic effects of VNS in children and adults with autism and developmental disabilities.
- Conditions
- Autism Spectrum Disorder, Intellectual Disability, Autonomic Nervous System, Developmental Disability
- Trial name
- VNS (NCT06259201)
- Testing
- Vagus Nerve Stimulation
- Where
- 2 sites in United States
- Sponsor
- New York State Institute for Basic Research
Autism Spectrum Disorders
Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors
The purpose of this research study is to learn about the effects of supplemental intranasal oxytocin as a treatment for improving social difficulties in children and adolescents with autism.
- Trial name
- SOARS-B (NCT01944046)
- Testing
- double Blind Oxytocin Nasal Spray, Open Label intranasal oxytocin
- Where
- 7 sites in United States
- Volunteers
- 290 people
- Sponsor
- Linmarie Sikich
Music Therapy
Effects of Music Therapy on Sensory Processing, Adaptive Behavior and Social Interaction
The purpose of our study is to examine the effects of music therapy on sensory processing, adaptive behavior, and social interaction in individuals with autism.
- Trial name
- NCT06996795
- Testing
- music therapy, sensory integration
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
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