Clinical trials: Spectrum
Autism, Autistic Disorder
Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism
This study is a double blind treatment trial that will test if sulforaphane improves core symptoms in autism. The investigators expect to see clinical improvement in some of these areas.
- Conditions
- Autism, Autistic Disorder, Autism Spectrum Disorder, Autistic Behavior
- Trial name
- NCT02677051
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Rutgers, The State University of New Jersey
Autism Spectrum Disorder
Resources for Optimizing Outcomes in Toddlers on the Spectrum
The goal of this clinical trial is to assess whether telehealth-based Family Navigation (FN) expedites enrollment (e.g., reduces time in days) in community-based autism intervention for toddlers under the age of 4 living in Rural…
- Trial name
- ROOTS (NCT07086781)
- Testing
- Virtual Family Navigation, Educational Materials
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
PIK3CA-Related Overgrowth Spectrum
A Study of the Epidemiology and Hospital Management of Patients With PROS in France
The purpose of this study was to estimate the incidence and prevalence of a group of genetic disorders known as PIK3CA-Related Overgrowth Spectrum (PROS) in France.
- Trial name
- EpiPROS (NCT07222423)
- Where
- United States
- Volunteers
- 3,605 people
- Sponsor
- Novartis Pharmaceuticals
Neurodevelopmental Disorders, Intellectual Disability
Longitudinal Study of Neurogenetic Disorders
The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medical problems and any treatment.
- Conditions
- Neurodevelopmental Disorders, Intellectual Disability, Developmental Delay, Autism Spectrum Disorder
- Trial name
- NCT03492060
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Columbia University
Autism, Stress
5Minutes4Myself: A Wellness Program for Caregivers
This research study refines a wellness program designed for caregivers of autistic children called 5Minutes4Myself and further investigates its feasibility.
- Conditions
- Autism, Stress, Autism Spectrum Disorder
- Trial name
- NCT03771001
- Testing
- Motivational Interviewing coaching and habit-building app
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Schizophrenia, Bipolar I Disorder
Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder
The purpose of this study is to evaluate the long-term safety and tolerability of cariprazine in the treatment of pediatric participants with schizophrenia, bipolar I disorder, or autism spectrum disorder (ASD) and to establish…
- Conditions
- Schizophrenia, Bipolar I Disorder, Autism Spectrum Disorder (ASD)
- Trial name
- 3070 Ped OLE (NCT04578756)
- Testing
- Cariprazine Flexible Dose
- Where
- 42 sites in United States, Puerto Rico
- Volunteers
- 310 people
- Sponsor
- AbbVie
Autism Spectrum Disorder
Cannabidivarin (CBDV) vs. Placebo in Children With Autism Spectrum Disorder (ASD)
This trial aims to study the efficacy and safety of cannabidivarin (CBDV) in children with ASD.
- Trial name
- NCT03202303
- Testing
- Cannabidivarin
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Montefiore Medical Center
Autism Spectrum Disorder
Effects of rTMS on Cognitive Functions and Behavior in Individuals With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with core symptoms that include impairments in social communication and restricted and repetitive behaviors, interests, and activities.
- Trial name
- NCT06524310
- Testing
- Stimulation with low frequency rTMS at 1 Hz
- Where
- Saudi Arabia
- Volunteers
- 35 people
- Sponsor
- King Saud University
Autism Spectrum Disorder
Integrated Platform for Measuring and Reducing Symptoms of Autism Spectrum Disorder
This study will consist of a randomized, double-blind, sham-controlled clinical trial at SUNY Upstate Medical University and Mt.
- Trial name
- IPMR ASD (NCT06006637)
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- State University of New York - Upstate Medical University
Autism Spectrum Disorder
SOCIAL: Adaptation and Validation of the In-person PEERS® Program for Adolescents With Autism.
Autism Spectrum Disorder (ASD) falls under the category of high complexity disorders which, in most cases, accompany individuals throughout their entire life with significant impacts and costs for individuals, their families, and…
- Trial name
- NCT07207213
- Testing
- PEERS, Control
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- IRCCS Fondazione Stella Maris
Autism Spectrum Disorder
Effect of Lithium in Patients With Autism Spectrum Disorder and Phelan-McDermid Syndrome (SHANK3 Haploinsufficiency)
There is currently no treatment for the body symptoms of Autism Spectrum Disorders (ASD). However, basic research suggests that some forms of ASD may be alleviated, even in the adult stage.
- Trial name
- Lisphem (NCT04623398)
- Testing
- Lithium Carbonate
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder
Proof of Concept Study on Pitolisant Effect on Autism Spectrum Disorders in Children and Adolescents
Proof of concept, multicenter, randomized, double-blind, placebo-controlled, parallel-group, study to investigate the effect, safety, tolerability and pharmacokinetics of pitolisant in male children and adolescents with Autism…
- Trial name
- NCT05953389
- Testing
- Pitolisant
- Where
- 15 sites in France, Italy and 2 more
- Volunteers
- 62 people
- Sponsor
- Bioprojet
Autism Spectrum Disorder
Metabolic Processes in Adults and Adolescents With Autism Spectrum Disorder
The objective of this study is to gain preliminary information and knowledge on metabolic profile in ASD. The benefit of this study will be to expand our insight of the potential relationship in metabolic processes and…
- Trial name
- ASD (NCT02733120)
- Testing
- stable isotope infusion
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Autism, Autism Spectrum Disorder
Trial of Cannabidiol to Treat Severe Behavior Problems in Children With Autism
There are very few treatments that are effective in reducing severe behavioral problems associated with autism. These behaviors include aggressive and self-harm behaviors, frequent repetitive behaviors and severe hyperactivity.
- Trial name
- NCT04517799
- Testing
- Epidiolex
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Diego
Autism Spectrum Disorder, Social Communication Disorder
Virtual Group Social ABCs - Multi-site Randomized Controlled Trial
The goal of this randomized control trial is to test the efficacy of the Social ABCs 6 week, group-based model using a virtual delivery platform.
- Conditions
- Autism Spectrum Disorder, Social Communication Disorder, Autism or Autistic Traits, Autism Spectrum Disorder With Impaired Functional Language
- Trial name
- NCT05663970
- Testing
- VG Social ABCs
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder, Autism
Posture, Hand Functions and Sensory Processing Skills on Nutrition
To examine the effects of posture, hand functions and sensory processing skills on nutrition in children with autism spectrum disorder.
- Conditions
- Autism Spectrum Disorder, Autism, Autism, Mild, ASD
- Trial name
- NCT06209463
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Fetal Alcohol Syndrome (FAS)
Epigallocatechin Gallate (EGCG) to Improve Cognitive Performance in Foetal Alcohol Syndrome (FAS) Children
The flavonoid epigallocatechin gallate (EGCG) is a modulator of neuronal plasticity useful in other neurodevelopmental diseases.
- Trial name
- Neuro-SAF (NCT02558933)
- Testing
- Epigallocatechin gallate
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Younger Sibling of Child With Autism Spectrum Disorder, Signs of Developmental Delay
Effects of a Short-term Parent Mediated Social Training on Developmental Trajectories in Infants
This study is being done to examine the feasibility and impact of the Infant Achievements caregiver coaching treatment on caregiver child-engagement strategies used during play with their infant.
- Conditions
- Younger Sibling of Child With Autism Spectrum Disorder, Signs of Developmental Delay, Signs of Communication Delay, Signs of Social Delay
- Trial name
- IA (NCT03404505)
- Testing
- Infant Achievements, Caregiver Education (CE)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autism Spectrum Disorder (ASD)
Associations of Autistic Traits and Feeding Difficulties
The objective is to assess the prevalence of autistic traits and feeding disorders in the general population.
- Trial name
- BAMBI2025 (NCT07188870)
- Where
- Hungary
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Teacher Help for Children and Youth With Mental Health Disorders
Currently, Canadian school systems are struggling to meet the needs of children with mental health disorders. It is particularly challenging to meet the needs of students with neurodevelopmental disorders (NDDs) within the…
- Conditions
- Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Learning Disabilities
- Trial name
- TeacherHelp (NCT02919215)
- Testing
- Teacher Help Intervention
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- IWK Health Centre