Clinical trials: Spectrum
Autism Spectrum Disorder
Care Improving Cognition for ADolescents on the Autism Spectrum
This is a validation study to evaluate the acceptability, feasibility and impact of CICADAS (Care Improving Cognition for ADolescents on the Autism Spectrum), a clinician-assisted, digital application that aims to prime the brain…
- Trial name
- CICADAS (NCT04562688)
- Testing
- CICADAS only, PEERS + CICADAS and then no-contact, PEERS + Active Comparator and then no-contact
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Posit Science Corporation
Autism Spectrum Disorder
Early Detection of Autism Spectrum Disorder in Children
Rationale: Autism Spectrum Disorder (ASD) is defined by deficits in social interaction and communication identified before the age of 3 years.
- Trial name
- NCT01646866
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Autism, Cognition Disorder
The Effect of Donepezil (Aricept(Registered Trademark)) on REM Sleep in Children With Autism
This study will test whether donepezil (Aricept(Registered Trademark)), a drug that is approved by the Food and Drug Administration to treat Alzheimer's disease, can increase rapid eye movement (REM) sleep in children with autism…
- Trial name
- NCT00695136
- Testing
- Donepezil hydrochloride, Increase REM sleep percentage
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Antipsychotic-induced Weight Gain (AIWG), Antipsychotic-induced Weight Gain
Dapagliflozin Versus Metformin for the Management of Antipsychotic-Induced Weight Gain: A Pragmatic Pilot Randomized Controlled Trial
The goal of this clinical trial is to learn whether dapagliflozin can help manage weight gain caused by antipsychotic medications in people aged 16 years or older who are receiving antipsychotic treatment and have developed…
- Trial name
- NCT07342764
- Testing
- Dapagliflozin, Metformin, Common Lifestyle Program
- Where
- Oman
- Volunteers
- 110 people
- Sponsor
- Sultan Qaboos University
Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome
Choline Supplementation in Children With Fetal Alcohol Spectrum Disorders
The purpose of this study is to determine whether choline supplementation can improve cognitive functioning of children with prenatal alcohol exposure.
- Conditions
- Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Partial Fetal Alcohol Syndrome, Alcohol-related Neurodevelopmental Disorder
- Trial name
- NCT01911299
- Testing
- Choline
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- San Diego State University
Anxiety, Attention Deficit Hyperactivity Disorder (ADHD)
Pilot Trial of a Social Skills Group Treatment (Secret Agent Society Program)
Several independent evaluations have supported the effectiveness of the Secret Agent Society (SAS) Program in improving the social-emotional functioning of children with Autism Spectrum Disorders (ASD) in clinic- (Beaumont \&…
- Conditions
- Anxiety, Attention Deficit Hyperactivity Disorder (ADHD), Autistic Spectrum Disorder (ASD)
- Trial name
- NCT02574273
- Testing
- Secret Agent Society (SAS) Program, Waitlist Group / Treatment As Usual
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Weill Medical College of Cornell University
Autism Spectrum Disorder
Development and Evaluation of a Parent-led Intervention Module for Early Autism Spectrum Disorder (PRIME-ASD) in Odisha, India: Protocol for a Multiphase Mixed-methods Study Including an Open-label Randomised Controlled Trial
Many families of young children with autism in India wait a long time for a diagnosis and specialist therapy, and receive little structured guidance on how to help their child at home.
- Trial name
- NCT07858383
- Testing
- Behavioral: PRIME-ASD (Parent-led Intervention Module for Early Autism Spectrum Disorder), Behavioral: PRIME-ASD; Other: Treatment as usual
- Volunteers
- 188 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Autism Spectrum Disorder, Social Communication
Joint Attention-Based Occupational Therapy Intervention in Pre-Schoolers With Autism Spectrum Disorder
In order to support the development of preschool children, joint attention training with activities incorporated in their natural routines can support the achievement of occupational therapy goals.
- Conditions
- Autism Spectrum Disorder, Social Communication, Behavior Problem, Visual Perceptual Weakness
- Trial name
- NCT05106166
- Testing
- Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Hacettepe University
Autism Spectrum Disorder, Social Communication
RCT to Evaluate Social Skills in Children With Autism Using VR Technology (SoCaVR)
The goal of this randomized clinical trial is to compare and learn about Virtual Reality (VR) in children with autism/Autistic children.
- Trial name
- SoCaVR (NCT06453629)
- Testing
- Floreo VR, VR Control, VR Control Crossover
- Where
- 17 sites in United States
- Volunteers
- 117 people
- Sponsor
- Floreo, Inc.
Autism
Sensory Adapted Dental Environments to Enhance Oral Care for Children
The goal of this project is to examine the efficacy of a sensory adapted dental environment (SADE) for children who have difficulty tolerating oral care in the dental clinic.
- Trial name
- SADE-2 (NCT02430051)
- Testing
- Sensory Adapted Dental Environment
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Psychotic Disorders, Psychosis Nos/Other
Psychosis Screening in Juvenile Justice
This study will investigate the occurrence of psychosis-spectrum disorders among youth in the Juvenile Justice System and track mental health referrals for these youth in Phase 1, a standard care condition.
- Trial name
- JJ-Psychosis (NCT03583073)
- Testing
- Enhanced Referral/Linkage to Care, Standard Care
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- Brown University
Obesity, Vitamin D Deficiency
Vitamin D Supplementation in Psychiatric Illnesses
Children and adolescents with psychiatric illnesses who are treated with medications called second generation antipsychotic agents (SGA) often gain excessive weight during their treatment with these medications.
- Conditions
- Obesity, Vitamin D Deficiency, Psychosis, Schizophrenia
- Trial name
- VDSS (NCT01004354)
- Testing
- Ergocalciferols
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Massachusetts, Worcester
Autism
Behavior, Neuropsychology, Neuroimage and Electrophysiology in Autistic Individuals With and Without CNVs
The study aims to investigate whether neuropsychological function (particularly cognitive flexibility and executive function), functional (assessed by resting functional MRI, rfMRI) and structural connectivity (assessed by DSI)…
- Trial name
- NCT01582256
- Where
- Taiwan
- Volunteers
- 132 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Efficacy of IMPACT in Infant Siblings of Children With ASD
Over a 5 year period infant and baby siblings of children with autism spectrum disorders (ASD) will be recruited to this study and will be randomized into 2 groups.
- Trial name
- IMPACT (NCT03274622)
- Testing
- Impact Parent Training, No Impact
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Vanderbilt University
Autism, Attention Deficit Hyperactivity Disorder
a2 Milk for Autism and Attention-deficit Hyperactivity Disorder (ADHD)
Under double-blind, placebo-controlled, cross-over conditions, the short-term effects of use of A1 beta casein free milk (a2 milk) and milk containing A1 beta casein will be compared in a sample of pre-pubescent boys diagnosed…
- Conditions
- Autism, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
- Trial name
- A2MT (NCT02911194)
- Testing
- a2 milk, a1 containing milk
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Drug Resistant Epilepsy, Autism Spectrum Disorder
Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients
The goal of this observational study is to learn about the clinical and nutritional effectiveness of ketogenic diet (KD) in pediatric patients with genetic, neurological or metabolic conditions requiring KD.
- Conditions
- Drug Resistant Epilepsy, Autism Spectrum Disorder, Chronic Migraine, Brain Tumor, Pediatric
- Trial name
- NCT06309251
- Testing
- ketogenic diet (as per clinical practice)
- Where
- 3 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Danone Nutricia SpA Società Benefit
Autism Spectrum Disorder
Neuropsychomotor Functions in Children With Autism Spectrum Disorder
The aim of the study is to describe the feasibility of the passation of the assessment battery of psychomotor functions tests (NP-MOT) in children aged 4 to 11 years with a diagnosis of autism spectrum disorder: number and type…
- Trial name
- NCT01987037
- Testing
- neuropsychomotor assessment
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Esquirol
Encopresis, Autism Spectrum Disorder
Treatment of Encopresis in Children With Autism Spectrum Disorders
This study is comparing a multidisciplinary intervention for encopresis (MIE), consisting of both medical and behavioral components to treatment as usual control (TAU).
- Trial name
- NCT03197922
- Testing
- MIE Treatment, Glycerin Suppository, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Emory University
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Clinical, Environmental, Neurocognitive, Brain Imaging, and Genetic Validity of Autism and ADHD
The behavioral patterns, neurocognitive and social impairments, and high heritability are the common characteristics of autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), the two most common…
- Trial name
- NCT00916851
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Bipolar I Disorder, Schizophrenia
Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects
To evaluate the long-term safety and tolerability of OLZ/SAM in pediatric subjects with schizophrenia or Bipolar I disorder
- Trial name
- NCT04987229
- Testing
- OLZ/SAM
- Where
- 35 sites in United States, Argentina and 3 more
- Volunteers
- 236 people
- Sponsor
- Alkermes, Inc.
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