Clinical trials: Spinal Disorders/Injuries
Spinal Cord Injury
Development of an Instrumental Activities of Daily Living Scale
This study is to develop an IADL Scale for patients with SCI (IADL-SCI) and examine its psychometric properties in three years.
- Trial name
- NCT00173784
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Psychological Well-Being, Spinal Cord Injuries
Self-Management Program for AIS D SCI
About 25-51% of adults with acquired spinal cord injury (SCI) have "AIS D" SCI, the lowest severity grade of neurologic injury. Veterans with AIS D SCI generally have better outcomes in mobility, community integration, and…
- Trial name
- SCISM-D (NCT05800717)
- Testing
- SCI Self-Management for AIS D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries (SCI)
Epidural Spinal Cord Stimulation for Restoring Walking in Spinal Cord Injury
The goal of this clinical trial is to evaluate the safety and effectiveness of Epidural Electrical Stimulation (EES) combined with rehabilitation training for the reconstruction of walking in patients with chronic spinal cord…
- Trial name
- NCT07306052
- Testing
- Epidural spinal cord stimulation, Rehabilitation Therapy, positron emission tomography-computed tomography (PET-CT)
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Spinal Cord Injuries
Brainwave Control of a Wearable Robotic Arm for Rehabilitation and Neurophysiological Study in Cervical Spine Injury
CSI:Brainwave is a multidisciplinary neurophysiological project, developed by the Lab of Medical Physics, School of Medicine, Aristotle University of Thessaloniki and supported by two Neurosurgical Departments.
- Trial name
- CSI:Brainwave (NCT02443558)
- Testing
- Brain-Computer Interface control of robotic arms., MERCURY v2.0 robotic arms
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Neurogenic Detrusor Overactivity
Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC
The purpose of this study is to evaluate the safety, efficacy, and PK of Vibegron in pediatric participants with NDO who are regularly using CIC
- Trial name
- KANGUROO (NCT05491525)
- Testing
- Vibegron
- Where
- 38 sites in United States, Belgium and 14 more
- Volunteers
- 71 people
- Sponsor
- Urovant Sciences GmbH
Cerebral Palsy, Traumatic Brain Injuries
Effects of an Adapted Ski/Snowboarding Program on Quality of Life in Children With Physical Disabilities
This study is assessing quality of life in children with a physical disability who participate in the Children's Hospital Colorado Hospital Sports Program (HSP), where children with physical disabilities are able to participate…
- Conditions
- Cerebral Palsy, Traumatic Brain Injuries, Spinal Cord Injuries, Physical Disability
- Trial name
- NCT02110290
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Colorado, Denver
Spinal Cord Injuries (SCI)
Spatiotemporal tSCS in Spinal Cord Injury
Spinal cord injury leads to long-lasting impairment, and currently, there is no cure for paralysis. Although transcutaneous spinal cord stimulation has shown promising results in recovering lost movements, its poor selectivity in…
- Trial name
- NCT07397559
- Testing
- No Stimulation, Conventional tSCS, Spatiotemporal tSCS
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Washington University School of Medicine
Spinal Cord Injury
Safety and Efficacy of Stem Cell Therapy in Spinal Cord Injury
The aim of this study was to study the effect of stem cell therapy on common symptoms of spinal cord injury patients.
- Trial name
- NCT02027246
- Testing
- Autologous bone marrow mononuclear cell transplantation
- Where
- India
- Sponsor
- Neurogen Brain and Spine Institute
Spinal Cord Injury, Urinary Tract Infection
Colonizing Neurogenic Bladders With Benign Flora
The purpose of the research is to determine whether we can get harmless bacteria to live in the bladders of persons with spinal cord injury who practice intermittent bladder catheterization.
- Trial name
- NCT00371631
- Testing
- Insertion of urinary catheters coated with E. coli 83972
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- US Department of Veterans Affairs
Adaptive Sport in Spinal Cord Injury
Study About Acting of Adaptive Sport in Musculoskeletal, Cardiovascular System and the Quality of Life of Individuals With Spinal Cord Injury Through Biomedical Instrumentation
The hypothesis is to the fulfillment of canoeing, handbike and conventional physiotherapy activities the groups could show improvement in muscle strength of the arms, decreased resistance of the lower limbs (spasticity), improved…
- Trial name
- Adaptive sport (NCT02177929)
- Testing
- adapted canoeing, hadbike and conventional physiotherapy
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade do Vale do Paraíba
Urinary Incontinence, Spinal Cord Injury
Lumbar to Sacral Ventral Nerve Re-Routing
To assess the level of improvement in voiding function after lumbar to sacral ventral nerve re-routing procedure in Spinal Cord Injury and spina bifida patients
- Conditions
- Urinary Incontinence, Spinal Cord Injury, Spina Bifida
- Trial name
- NCT00378664
- Testing
- lumbar to sacral ventral nerve re-routing procedure
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kenneth Peters, MD
Lumbar Pain Syndrome
Evaluation and Timing in an ERAS-like Structured Rehabilitation Program After Lumbar Spine Surgery
The goal of this clinical trial is to investigate the safety of early inpatient rehabilitation after lumbar spine surgery. Participants are assigned to therapy groups C (low) - A (high) intensity and receive standardized…
- Trial name
- NCT05937997
- Testing
- high intensity physiotherapy, moderate intensity physiotherapy, low intensity physiotherapy
- Where
- Germany
- Volunteers
- 245 people
- Sponsor
- Median
Spinal Cord Injury
Self-Catheterization Mirror System for Female Patients
The purpose of this study is to test a modified mirror system for female patients to use during self-catheterization.
- Trial name
- NCT05406258
- Testing
- Modified Self-Catheterization Mirror, Standard Self-Catheterization Mirror
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury at C5-C7 Level, Spinal Cord Injuries
Grasp-Release Assessment of a Networked Neuroprosthesis Device
The overall objective of this trial is to characterize the safety and effectiveness of the Networked Neuroprosthesis Device - Upper Extremity (NP-UE) in individuals living with cervical SCI.
- Conditions
- Spinal Cord Injury at C5-C7 Level, Spinal Cord Injuries, Spinal Cord Injury Cervical
- Trial name
- GRANND (NCT05863754)
- Testing
- Networked Neuroprosthesis Device
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- MetroHealth Medical Center
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University
Spina Bifida, Cerebral Palsy
Grand Valley State University (GVSU) Skills on Wheels
Manual wheelchairs (MWCs) are widely used by children with physical disabilities, yet many of these children are unable to use their wheelchair independently. Instead, they depend on others to push them.
- Conditions
- Spina Bifida, Cerebral Palsy, Genetic Disease, Spinal Cord Injuries
- Trial name
- NCT05339932
- Testing
- Manual Wheelchair Skills Training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Grand Valley State University
Parkinson Disease, Dystonia
Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia
This study will determine if posture and heart rate variability will significantly improve in Parkinsons disease with camptocormia after osteopathic manual treatments dystonia.
- Conditions
- Parkinson Disease, Dystonia, Autonomic Dysreflexia
- Trial name
- NCT03307161
- Testing
- osteopathic manual therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York Institute of Technology
Exercise, Spinal Cord Injuries
EFFECTS OF ROBOTIC TRAINING ON VASCULAR HEALTH OF INDIVIDUALS WITH SCI
Robotic devices may be used to help the gait and balance of individuals with Spinal Cord Injury (SCI). However, as such devices may allow individuals to engage in physical activity in an upright position, there may be significant…
- Trial name
- NCT03611803
- Testing
- Physiotherapy + Robotic-device, Physiotherapy only
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Winchester
Osteoarthritis, Osteosarcoma
Clinical Orthopaedic Data Bank (Acute and Chronic)
Data involving orthopaedic conditions and rehabilitation aspects of musculoskeletal and neuromuscular disorders will be collected and stored as part of the normal clinical care of patients seen in the University of Florida (UF)…
- Conditions
- Osteoarthritis, Osteosarcoma, Scoliosis, Cerebral Palsy
- Trial name
- NCT00411060
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- University of Florida
Scoliosis
Effectiveness of Bracing in Preventing Scoliosis in Children With Spinal Cord Injury
The purpose of this study is to determine whether full-time high dose prophylactic bracing (23 hours or more per day) is more effective than low dose bracing (12 hours or less per day) in preventing or delaying spinal curve…
- Trial name
- NCT00256672
- Testing
- Thoraco-Lumbar-Sacral-Orthoses (TLSO) / Flex-Foam
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- Shriners Hospitals for Children