Clinical trials: Spinal Disorders/Injuries
Acute Stroke, Cervical Spinal Cord Injury
Motor Recovery Training for Hand and Digits in Stroke and SCI
This study will use evaluate a hand therapy device training isolated finger control with engaging video gaming technology to facilitate hand and digit recovery in patients with acute stroke and cervical spinal cord injury.
- Trial name
- NCT04688229
- Testing
- Hummingbird hand training device plus standard of care rehabilitation
- Volunteers
- 24 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury(SCI)
Exploration of the Effectiveness and Mechanism of Personalized Epidural Electrical Stimulation in Improving Upper Limb Function in Participants With Spinal Cord Injury
This study aimed to determine whether cervical spinal cord epidural electrical stimulation (EES) can activate upper-limb muscles in individuals with spinal cord injury.
- Trial name
- NCT07722429
- Testing
- Epidural electrical stimulation (EES)
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Spinal Cord Injuries
Multimodality Intervention for Function and Metabolism in SCI
The proposed phase 2 trial a randomized, placebo-controlled, parallel group trial in persons with cervical or thoracic SCI, AIS grade A, B, C, or D, 6 months or later after injury.
- Trial name
- NCT03576001
- Testing
- Testosterone Undecanoate, hybrid exercise
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Spinal Cord Injuries, Self-Management
Improving Self-Management Skills Among People With Spinal Cord Injury
The goal of our study is to evaluate the use of a self-management application ("app") that the investigators have developed to help facilitate self-management among individuals with SCI who live in the community.
- Conditions
- Spinal Cord Injuries, Self-Management, Mobile Application
- Trial name
- MobileApp (NCT03140501)
- Testing
- Mobile application ("app")
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Spinal Cord Injuries
Seated Balance Using the Indego™
Exoskeleton-assisted walking (EAW) provides a new mobility option and appears to have potential therapeutic benefits for persons with SCI. However, present day technology is not sufficient to replace the wheelchair.
- Trial name
- NCT04047992
- Testing
- Indego™ Exoskeleton
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Injuries, Spinal Cord
Sit-to-stand With Feedback in SCI Patients
Does the utility of external feedback in terms of goal-directed LLL approach during STS training immediately improve functional ability relating to walking in ambulatory patients with SCI? Does the utility of LLL feedback improve…
- Trial name
- NCT02913911
- Testing
- feedback
- Volunteers
- 15 people
- Sponsor
- Khon Kaen University
Spinal Cord Injury, Spinal Cord Injury Cervical
Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury
Stimulation of the spinal cord and brain represents a new experimental therapy that may have potential to restore movement after spinal cord injury.
- Trial name
- NCT06867809
- Testing
- Epidural spinal cord stimulation and paired spine and brain stimulation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Jason Carmel
Shoulder Pain, Shoulder Impingement Syndrome
Micro-Fragmented Adipose Tissue (Lipogems®) Injection for Chronic Shoulder Pain in Persons With Spinal Cord Injury
Rotator cuff disease (i.e., rotator cuff tendinopathy or tear) is a common cause of shoulder pain in persons with chronic spinal cord injury (SCI).
- Conditions
- Shoulder Pain, Shoulder Impingement Syndrome, Rotator Cuff Impingement Syndrome, Rotator Cuff Tendinitis
- Trial name
- NCT03167138
- Testing
- Autologous micro-fragmented adipose tissue, Lipogems system
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Neurogenic Bladder
Effect of Electroacupuncture at Different Acupoints on Bladder Function After Spinal Cord Injury
Neurogenic bladder after spinal cord injury can be divided into detrusor hyperreflexia and detrusor non reflexia. Acupuncture is recognized as a safe and effective treatment.
- Trial name
- NCT05262816
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Tetraplegia/Tetraparesis, Quadriplegia
CAN-PRIME: Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices
The CAN-PRIME Study is to test the safety and functionality of Neuralink's N1 Implant and R1 Robot in people who have difficulty moving their arms and legs (tetraparesis or tetraplegia).
- Conditions
- Tetraplegia/Tetraparesis, Quadriplegia, Quadriplegia/Tetraplegia, Cervical Spinal Cord Injury
- Trial name
- CAN-PRIME (NCT06700304)
- Testing
- N1 Implant, R1 Robot
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Neuralink Corp
Spinal Cord Injuries
Kayak Ergometer Training in Individuals With Spinal Cord Injury
One of the main objectives in spinal cord injury rehabilitation programs is the improvement of trunk control in order to achieve independence, to prevent complications and, in specific cases to walk.
- Trial name
- NCT03531164
- Testing
- kAYAK ERGOMETER GROUP, CONTROL GROUP
- Where
- Mexico
- Volunteers
- 18 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Cerebral Palsy (CP), Spastic Paraplegia
Retrospective Study on the WalkOn AFO in Children or Teenagers With Neurological Pathologies
The goal of this observational study is to assess the interest of prefabricated carbon fiber ankle foot orthoses (AFO) in children and teenagers with central or peripheral neurological pathologies.
- Conditions
- Cerebral Palsy (CP), Spastic Paraplegia, Spinal Cord Injuries (SCI), Spina Bifida
- Trial name
- NCT06740006
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Otto Bock France SNC
Spinal Cord Injury
Self-Catheterization Mirror System for Female Patients
The purpose of this study is to test a modified mirror system for female patients to use during self-catheterization.
- Trial name
- NCT05406258
- Testing
- Modified Self-Catheterization Mirror, Standard Self-Catheterization Mirror
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries, Peripheral Nerve Injuries
Upper Extremity Functional Electrical Stimulation (FES) for Restoration of Upper Extremity Function After Spinal Cord Injury (SCI)
The purpose of this research is to examine the effects that functional electrical stimulation (FES) therapy has on the way the arms, brain and spinal cord work.
- Trial name
- NCT06672458
- Testing
- MyndMove Short Term Therapy, Conventional Short Term Therapy, MyndMove Long Term Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Miami
Spinal Cord Injury, Orthostatic Hypertension
Non-invasive Spinal Cord Stimulation and Blood Pressure Regulation After Spinal Cord Injury
The goal of this clinical trial is to learn if non-invasive spinal cord stimulation intervention improves blood pressure regulation in individuals with chronic spinal cord injury.
- Conditions
- Spinal Cord Injury, Orthostatic Hypertension, Autonomic Dysreflexia
- Trial name
- NCT07504055
- Testing
- Spinal Cord Transcutaneous Stimulation
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Louisville
Analgesia, Pain, Postoperative
Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine Surgery
The rationale for multimodal analgesia is to achieve additive or synergistic analgesic properties while decreasing the incidence of side effects by reducing the dose of each agent.
- Conditions
- Analgesia, Pain, Postoperative, Spinal Stenosis, Spinal Disease
- Trial name
- NCT04391855
- Testing
- Tramadol with ropivacaine, Dexmedetomidine with ropivacaine, Magnesium with ropivacaine
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- Aristotle University Of Thessaloniki
Spinal Cord Injury
Synchronous Tele-Resistance Training to Improve Upper Extremity Function in Patients With Spinal Cord Injury
This study investigated the effects of resistive exercises applied with synchronized telerehabilitation on upper extremity functions in patients with SCI who use wheelchairs.
- Trial name
- TELERES-SCI (NCT07115693)
- Testing
- Telerehabilitation-Based Resistance Exercise Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Hacer Önen Tekin
Spinal Cord Injuries
Manually Assisted Cough Technique and Incomplete Cervical Spine Injury
To determine the effectiveness of manually assisted cough technique on peak cough flow and pulmonary functions in patients with incomplete cervical spine injury. Previous studies were designed to target only a small sample.
- Trial name
- NCT04741126
- Testing
- Manually assisted cough technique
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Spinal Cord Injuries (SCI), Neurogenic Lower Urinary Tract Dysfunction
Radio-frequency (RF) Bladder Monitor
The goal of this pilot feasibility study is to evaluate a wearable microwave (MW)-based bladder monitoring system in adult volunteers and those with spinal cord injury (SCI) who use self-catheterization for bladder management.
- Conditions
- Spinal Cord Injuries (SCI), Neurogenic Lower Urinary Tract Dysfunction, Neurogenic Bladder (NB)
- Trial name
- NCT07639541
- Testing
- Wearable microwave Bladder Monitoring System
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Spinal Cord Injury
Customized Employment for Veterans With Spinal Cord Injury
The reason for conducting this study is to learn about the best ways to help Veterans with spinal cord injury (SCI) gain meaningful employment.
- Trial name
- ACCESS-Vets (NCT04832802)
- Testing
- ACCESS, IPS
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
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