Clinical trials: Spinal Surgery
Pain, Postoperative
Spinal Versus Caudal Analgesia After Pediatric Infra-umbilical Surgery
Caudal analgesia along with general anesthesia is a very popular regional technique for prolonged postoperative analgesia in different pediatric surgical procedures where the surgical site is sub-umbilical.
- Trial name
- ITVSEpidural (NCT02988700)
- Testing
- Intrathecal hyperbaric bupivacaine 0.25mg/kg 0.5%, caudal plain bupivacaine 2.5mg/kg 0.25%
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Scoliosis; Adolescence, Pain After Surgery
Tegileridine for Postoperative Pain After Adolescent Scoliosis Surgery
The goal of this clinical trial is to see if a new pain medicine called Tegileridine is at least as effective as morphine (the standard treatment) for pain relief after spinal surgery in teenagers with scoliosis.
- Conditions
- Scoliosis; Adolescence, Pain After Surgery, Analgesia, Patient-controlled
- Trial name
- NCT07229495
- Testing
- Tegileridine, morphine
- Where
- 6 sites in China
- Volunteers
- 171 people
- Sponsor
- Peking Union Medical College Hospital
Spinal Cord Injuries
Early Surgical Intervention Combined With Weight-supported Walking Training
To determine the efficacy of a novel combinatorial treatment involving early surgical intervention and long-term weight-bearing walking training in spinal cord injury (SCI) patients clinically diagnosed as complete or American…
- Trial name
- NCT04034108
- Testing
- Surgical intervention combined with weight-supported ambulation training
- Where
- 2 sites in China
- Volunteers
- 339 people
- Sponsor
- Kunming Tongren Hospital
Other Acute Postoperative Pain
Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia
We conducted a prospective, randomized double-blind study to compare the effectiveness of intravenous paracetamol and dipyrone for preventing pain during early postoperative period in school-age children undergoing lower…
- Trial name
- NCT01858402
- Testing
- Paracetamol, Dipyrone
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baskent University
Spine Deformities, Idiopathic Scoliosis
Blood Propofol Concentrations in Children During Spinal Surgery
During major spinal surgery evoked potential monitoring is performed to detect spinal cord damage. Intra-venous anaesthesia is the preferred anaesthetic technique because volatile anaesthetic agents supress the evoked potentials.
- Conditions
- Spine Deformities, Idiopathic Scoliosis, Neuromuscular Dystrophy
- Trial name
- NCT01932424
- Testing
- Pelorus 1500, Propofol 2% (Diprivan 2%, Astra Zeneca UK)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Healthy, Hyperalgesia
Influence of Genetics in Pain Sensitivity
The purpose of this study is to learn more about the role of genetics in pain sensitivity. Pain perception varies widely among individuals, and information gained from this trial may lead to better methods of preventing and…
- Conditions
- Healthy, Hyperalgesia, Pain
- Trial name
- NCT00001956
- Testing
- Blood draw, Oral surgery, Tissue biopsy
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Scoliosis, Spondylolisthesis
Effect of Pregabalin on Immediate Post-operative and Longterm Pain
This study aims to evaluate the incidence of longterm pain after spinal fusion surgery in children and adolescents. In the second part of the study a randomized double-blind clinical trial will be conducted.
- Trial name
- NCT02464813
- Testing
- Pregabalin, Sugar pill, Oxycodone
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Turku University Hospital
Adolescent Idiopathic Scoliosis
Minimally Invasive Surgery vs Standard Posterior Approach in the Treatment of Developmental Idiopathic Scoliosis
This is a randomized trial with 1:1 allocation. The aim of the study is to evaluate clinical and radiographic outcomes in patients with developmental age idiopathic scoliosis treated with mini invasive scoliosis surgery (MIS)…
- Trial name
- NCT05860673
- Testing
- mini invasive scoliosis surgery, posterior spinal fusion technique
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Istituto Ortopedico Rizzoli
Open Spina Bifida, Myelomeningocele
Fetoscopic Open Spina Bifida Repair Using the SAFER Technique
Children submitted to fetoscopic in utero myelomeningocele repair using the SAFER (Skin-over-biocellulose for Anternatal FEtoscopic Repair) technique will evaluate at 30 months or more, regarding ambulation, neurodevelopment…
- Conditions
- Open Spina Bifida, Myelomeningocele, Meningomyelocele, Chiari Malformation With Spina Bifida
- Trial name
- NCT04356703
- Testing
- Neuropsicomotor developmental test
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital Israelita Albert Einstein
Pain, Spinal Surgeries, Hip and Knee Joint Replacement, Adverse Events
RAHM Foundation Retrospective Study of Various Diseases
This is a retrospective data collection on treatment of various disorders. This registry will include a variety of different products, implants, technologies and procedures.
- Trial name
- NCT02359786
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Rahm Foundation
Hypertrophic Pyloric Stenosis, Spinal Anesthesia
Spinal Anesthesia and General Anesthesia for Pyloromyotomy - Surgical Outcomes a Comparison Retrospective Study
Background: The purpose of this retrospective study is to evaluate surgical outcomes of pyloromyotomy in infants performed under spinal anesthesia compares to general anesthesia.
- Conditions
- Hypertrophic Pyloric Stenosis, Spinal Anesthesia, General Anesthesia
- Trial name
- NCT03095144
- Testing
- Spinal anesthesia, General anesthesia
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Spinal Cord Injuries
Duroplasty for Injured Cervical Spinal Cord With Uncontrolled Swelling
QUESTION. Does duroplasty improve outcome after spinal cord injury? WHAT DO WE STUDY? We will investigate whether performing a surgical procedure called duroplasty improves outcomes after spinal cord injury.
- Trial name
- DISCUS (NCT04936620)
- Testing
- Duroplasty, Spinal surgery
- Where
- 34 sites in Austria, Belgium and 10 more
- Volunteers
- 222 people
- Sponsor
- St George's, University of London
Adolescent Idiopathic Scoliosis
Coping After Pediatric Scoliosis Surgery
This is a prospective, randomized controlled trial evaluating the efficacy of expanded patient education and coping skills on pain management following multilevel pediatric spinal surgery.
- Trial name
- CAPS (NCT04063670)
- Testing
- Video Intervention, Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Scoliosis
Value of 3D Modeling in Spine Surgery
Adults (18 years and over) and children (10-17 years of age) scheduled for surgery to correct scoliosis will be included in this study, for which participation will last 6 months.
- Trial name
- NCT02771899
- Testing
- spineEOS software, EOS
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Columbia University
Fibrinogen, Spine Deformity
Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery
EFISS is a prospective, randomized, placebo-controlled trial testing the feasibility, safety and efficacy of prophylactic administration of fibrinogen in paediatric spinal surgery.
- Conditions
- Fibrinogen, Spine Deformity, Coagulopathy, Consumption, Bleeding
- Trial name
- EFISS (NCT05391412)
- Testing
- Fibrinogen Concentrate Human
- Where
- Czechia
- Volunteers
- 32 people
- Sponsor
- Brno University Hospital
Lumbar Pain Syndrome
Evaluation and Timing in an ERAS-like Structured Rehabilitation Program After Lumbar Spine Surgery
The goal of this clinical trial is to investigate the safety of early inpatient rehabilitation after lumbar spine surgery. Participants are assigned to therapy groups C (low) - A (high) intensity and receive standardized…
- Trial name
- NCT05937997
- Testing
- high intensity physiotherapy, moderate intensity physiotherapy, low intensity physiotherapy
- Where
- Germany
- Volunteers
- 245 people
- Sponsor
- Median
Scoliosis
Study of the Surgical Treatment of Early Onset Scoliosis Using a Non-invasive Growing Rod
It is current practice for children who have surgery for early onset scoliosis (EOS) to be treated with insertion of extendable implants known as growth rod systems.
- Trial name
- NCT01362881
- Where
- 2 sites in United Kingdom
- Volunteers
- 14 people
- Sponsor
- Ellipse Technologies, Inc.
Surgical Injury, Back Pain Lower Back Chronic
Spinal Approach for Lumbar Active Discopathy
The study aims to study the impact on different surgical approaches for lumbar active discopathy. This inflammatory disease of the disc and adjacent vertebral endplates can induce low back pain with inflammatory-like features.
- Trial name
- NCT04086199
- Testing
- Lumbar discectomy
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Neurogenic Incontinence, Dysfunctional Voiding
Treatment of Neurogenic Incontinence by Surgery to Cut the Filum Terminale
The target population of this study is children with primary or secondary daytime urinary incontinence, who have failed to improve adequately despite compliance with at least 6 months of standard medical therapy.
- Trial name
- NICNOC (NCT01465581)
- Testing
- Division of the filum terminal
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nemours Children's Clinic
Constipation, Ileus
Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery
This study investigated the effect of preoperative bowel preparations for patients undergoing spinal fusion surgery.
- Conditions
- Constipation, Ileus, Surgery
- Trial name
- NCT01879605
- Testing
- Docusate natrium and sorbitol, Bisacodyl
- Where
- Norway
- Volunteers
- 45 people
- Sponsor
- Oslo University Hospital