Clinical trials: Splenectomy
End Stage Liver Disease
Splenectomy During Whole Liver Transplantation
Indications for splenectomy during whole liver transplantation remain controversial and splenectomy is often avoided because of common complications.
- Trial name
- NCT03609411
- Testing
- Splenectomy
- Where
- France
- Volunteers
- 141 people
- Sponsor
- Hospices Civils de Lyon
Hypertension, Portal, Portal Vein, Cavernous Transformation Of
Percutaneous Transhepatic Intrahepatic Portosystemic Shunt for Treatment of Portal Vein Occlusion With Symptomatic Portal Hypertension After Splenectomy
To evaluate the values of percutaneous transhepatic intrahepatic portosystemic shunt for treatment of portal vein occlusion with symptomatic portal hypertension after splenectomy.
- Trial name
- NCT02505152
- Testing
- Percutaneous transhepatic intrahepatic portosystemic shunt
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Hereditary Spherocytosis, Idiopathic Thrombocytopenic Purpura
Single Incision Versus Standard Laparoscopic Splenectomy
This is a prospective trial of single incision versus standard 4-port laparoscopic splenectomy. The hypothesis is that there may be a difference in wound infection rates, operative time, doses of analgesics post-operatively, and…
- Trial name
- NCT01276561
- Testing
- Single Incision Splenectomy, Laparoscopic Splenectomy
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Sickle Cell Anemia, Thalassemia
The Spleen in Sickle Cell Anemia and Sickle Cell Thalassemia
The spleen in Sickle Cell Anemia and Sickle Cell Thalassemia is usually enlarged in the first years of life but the immune protection provided is considered insufficient.
- Trial name
- NCT00971698
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- HaEmek Medical Center, Israel
Grade III Traumatic Splenic Injury in Hemodynamically Stable Patients
Traumatic Injury of Spleen:Laparoscopic Splenectomy Vs Splenic Artery Embolization
The goal of this clinical trial is selection of the best method in management of grade 3 traumatic Splenic Injury in Hemodynamically Stable Patients thus improving the quality of life and clinical outcome.
- Trial name
- NCT07274007
- Testing
- Laparoscopic Splenectomy vs splenic Artery Embolization
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Trauma Splenic
Long Term Effect of Splenectomy on Metabolism
Metabolic status of patients who had gone through trauma splenectomy between July 2008 and July 2013 were compared to patients who had gone through bowel resection due to obstruction in the same period of time.
- Trial name
- NCT03648307
- Testing
- Blood sample
- Volunteers
- 154 people
- Sponsor
- Imam Hossein General Hospital
Splenectomized Patients
Post Splenectomy Care Assessment and the Role of Patient Education in Its Improvement
The goal of this trial is to evaluate compliance to booster vaccines and chemoprophylaxis in children who underwent a splenectomy and to assess the knowledge regarding this aspect before and after giving education.
- Trial name
- NCT07027371
- Testing
- Health education
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Cairo University
Non Traumatic Splenic Rupture
Non-traumatic Rupture of the Spleen. Can Splenectomy be Applied Selectively?
Purpose: Non-traumatic rupture of the spleen should be suspected when patients (especially young men) present with abdominal pain and a history of acute infectious or myeloproliferative disorders.
- Trial name
- NCT01845662
- Testing
- Surgical or non-surgical management
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Ziv Hospital
Splenectomy; Status
A Nationwide Italian Survey on Asplenia
Spleen is involved in several functions, such as the production of protective antibodies, the removal of unwanted particulate matter from the blood (eg bacteria) and also the storing of blood cells, especially white cells and…
- Trial name
- NCT03571399
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Società Italiana Talassemie ed Emoglobinopatie
Splenic Injury
Treatment of Splenic Trauma: a Retrospective Cohort Study
In blunt trauma, the spleen is most frequent injured organ in the abdomen and the most frequent source of bleeding in the abdomen. Historically, splenectomy was the treatment of choice for splenic bleeding.
- Trial name
- NCT01965548
- Testing
- Treatment of splenic injury
- Where
- Norway
- Volunteers
- 109 people
- Sponsor
- University Hospital of North Norway
Hereditary Spherocytosis
The Dallas Hereditary Spherocytosis Cohort Study
The purpose of this study is to 1. better characterize the short term and long term natural history of hereditary spherocytosis (HS) including diagnosis, complications, and indications for and response to splenectomy 2.
- Trial name
- NCT01141621
- Volunteers
- 55 people
- Sponsor
- University of Texas Southwestern Medical Center
Hemophagocytic Lymphohistiocytosis
Splenectomy as a Treatment for Patient With Relapsed Haemophagocytic Lymphohistiocytosis of Unknown Etiology
To evaluate the clinical value of splenectomy as a treatment for relapsed haemophagocytic lymphohistiocytosis (HLH) in patient with unknown etiology.
- Trial name
- NCT02862054
- Testing
- splenectomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Friendship Hospital
Laparoscopic Surgery
Laparoscopic Splenectomy in Isolated High Grades Splenic Injuries
Background: Trauma laparoscopic splenectomy has no defined reasons. Compared trauma patient characteristics and results with laparoscopic and open splenectomies.
- Trial name
- NCT04329845
- Testing
- open splenectomy, laparoscopic splenectomy for splenic injury in trauma
- Volunteers
- 2 people
- Sponsor
- Zagazig University
Regional Block, Pediatric
External Oblique Intercostal Block Versus Transversus Abdominis Plane Block in Pediatric Laparoscopic Splenectomy
The aim of study is to compare the efficacy of the External Oblique Intercostal plane block with the Transversus Abdominis Plane block in acute postoperative pain control in pediatric patients undergoing laparoscopic Splenectomy.
- Conditions
- Regional Block, Pediatric, Laparoscopic Splenectomy, External Oblique Intercostal Block
- Trial name
- NCT07336043
- Testing
- EOI group, TAP group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Appendicitis, Hernia
Aromatherapy Versus Acupressure: Impact on Postoperative Pain and Sleep Quality in Pediatric Abdominal Surgery Patients
The study's aim is to examine the effect of using aromatherapy versus acupressure on pain intensity and sleep pattern for children undergoing abdominal surgeries.
- Conditions
- Appendicitis, Hernia, Abdominal Exploration, Splenectomy
- Trial name
- NCT07157501
- Testing
- Accupressure, Aromatherapy inhaler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Laparoscopic Splenectomy, Children
Laparoscopic Splenectomy in Children
Laparoscopic splenectomy (LS) gained popularity since it has been described for the first-time during nineties of past century. It has become "golden method" for splenectomy in all ages including children
- Conditions
- Laparoscopic Splenectomy, Children, Benign Blood Diseases
- Trial name
- splenectomy (NCT04763733)
- Testing
- laparoscopic splenectomy
- Volunteers
- 137 people
- Sponsor
- Tanta University
Splenectomy; Status
Total Splenectomy vs Partial Splenectomy in Non-malignant Hemoglobinopathies : Study Comparing the Effectiveness
Partial splenectomy or total splenectomy are the two surgical treatment of non-malignant hemoglobinoptahie. The aim of this treatment is to decrease transfusion.
- Trial name
- NCT05184647
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Sleeve Gastrectomy, Cholecystectomy
Stanford Program to Accelerate Robotic Children's Surgery
The goal of this clinical trial is to provide additional data to confirm safety and performance of the da Vinci Xi Surgical System in a human clinical setting.
- Conditions
- Sleeve Gastrectomy, Cholecystectomy, Splenectomy, Hysterectomy
- Trial name
- SPARCS (NCT06671639)
- Testing
- da Vinci Xi Robotic Surgery System
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Stanford University
Splenomegaly, Splenectomy
Study of the Prevalence of Acid Sphingomyelinase Deficiency/Niemann Pick AB and B Disease in Patients With Diffuse Interstitial Lung Disease
The goal of this clinical trial is to optimise and facilitate screening for Acid SphingoMyelinase Deficiency (ASMD) disease, by evaluating acid sphingomyelinase activity and, where appropriate, LysoSM levels in a cohort of 200…
- Conditions
- Splenomegaly, Splenectomy, Thrombopenia, Interstitial Lung Disease (ILD)
- Trial name
- Niemann-PID (NCT06869499)
- Testing
- Blood sampling for dosage
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Wladimir MAUHIN, Dr
Thalassemia, Sickle Cell Anemia
Invasive Infections in Children With Hemoglobinopathies
Patients diagnosed as having hemoglobinopathies are exposed to serious bacterial infections, principally those patients that underwent splenectomy.
- Trial name
- NCT00456443
- Testing
- Historical records
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- HaEmek Medical Center, Israel