Clinical trials: Step
Amyotrophic Lateral Sclerosis
Evaluation of Palliative Care for Patients With ALS and Their Caregivers
Rationale: Amyotrophic lateral sclerosis (ALS) is a degenerative illness which currently has no medical cure. It is routinely accompanied by a significant symptom burden including high levels of distress in patients and their…
- Trial name
- NCT04257760
- Testing
- Palliative Care consultation outside standard of care
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- Ottawa Hospital Research Institute
Deep Caries
Multicenter Trial Comparing One-step Partial Caries Removal to Complete Caries Removal for the Treatment of Deep Carious Lesions in Permanent Teeth. (DECAT : DEep CAries Treatment).
This clinical trial is a national multicenter randomized controlled trial performed in parallel groups aiming to validate a treatment that preserves pulp vitality of mature permanent posterior teeth through partial removal of…
- Trial name
- DECAT (NCT02286388)
- Testing
- A one-step partial caries removal procedure for the treatment of deep carious lesions in posterior permanent teeth., A complete caries removal procedure for the treatment of deep carious lesions in posterior permanent teeth., The application of an antibacterial dental adhesive (ClearfilTM SE Protect, Kuraray Dental).
- Where
- 15 sites in France
- Volunteers
- 464 people
- Sponsor
- Hospices Civils de Lyon
Bimaxillary Protrusion
Evaluation of Mini and Macro-esthetics Following En- Masse Retraction Versus Two Step Retraction
There's a scarcity in literature concerning mini-esthetics specially maxillary gingival display changes following en-masse retraction and two-step retraction.
- Trial name
- NCT05150665
- Testing
- En-masse retraction, Two step Retraction
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Anxiety, Depression
Connecticut Child STEPs
Connecticut Child STEPS is a randomized controlled trail investigating the effectiveness of MATCH-ADTC in treating anxiety, depression, trauma, and/or behavioral problems in children seeking services at four Department of…
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03153904
- Testing
- Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems, Monitoring and Feedback System
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Harvard University
Left Bundle Branch Area Pacing
Transesophageal Echocardiography in Conductive System Pacing in Pediatric Patients
The investigatorse will use the guidance of Intraprocedural three-dimensional transesophageal echocardiography (3D-TEE) for Left Bundle Branch Area Pacing (LBBAP) lead implantation in pediatric patients.
- Trial name
- NCT07882563
- Testing
- Left Bundle Branch Pacing
- Volunteers
- 56 people
- Sponsor
- Assiut University
Monochromatic, L- and S-cone Modulation Only
Evaluating How Well Different Types of Light-sensitive Cells in the Eye Contribute to Its Focusing Ability
In this experiment, subjects will view shapes on a screen with varying colors and be asked to focus their eyes on the shapes. The shapes will look as though they are jumping to random distances away from the eye.
- Conditions
- Monochromatic, L- and S-cone Modulation Only, L- and M-cone Modulation Only, M and S-cone Modulation Only
- Trial name
- NCT07691463
- Testing
- Color
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rochester Institute of Technology
Anxiety, Depression
Child STEPS for Youth Mental Health in Maine Sustainability
The overarching goal of this project is to study the sustainability of MATCH-ADTC within community mental health clinics, to learn what is needed for evidence-based practices (EBPs) to take root and thrive within a public system.
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03112304
- Testing
- MATCH-ADTC, TRAC
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Harvard University
Food Allergy, Cow's Milk Protein Allergy
GOAt Milk Formula-based Ladder Versus Cow's Milk Ladder
Children with immunoglobulin E (IgE)-mediated cow's milk allergy (CMA) who react to small amounts of baked cow's milk may require prolonged elimination.
- Conditions
- Food Allergy, Cow's Milk Protein Allergy, Cow's Milk Allergy
- Trial name
- GOAL (NCT07795957)
- Testing
- oral food challenge (OFC)
- Where
- 2 sites in Poland
- Volunteers
- 92 people
- Sponsor
- Medical University of Warsaw
Early Gastric Cancer
the Train the Trainer (TTT) Plan, to Improve the Young Endoscopist's Ability to Find the Early Gastric Cancer
AIM Verified if the first stage of the Train the trainer (TTT)plan could improve the young endoscopist's ability to detect the early gastric cancer（EGC）. METHOD 1.
- Trial name
- NCT02385578
- Testing
- an educational intervention
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Poliomyelitis
IPV-102 Safety, Tolerability and Immunogenicity of TAK-195 in Healthy Infants, Toddlers and Adults
The purpose of this study is to select the optimal antigen dosage of the three Sabin poliovirus strains (types 1, 2, and 3) entering the composition of the stand-alone trivalent Sabin-based inactivated poliomyelitis vaccine…
- Trial name
- NCT03092791
- Testing
- Sabin-Based Inactivated Poliomyelitis Vaccine (sIPV), Reference IPV
- Where
- 4 sites in Panama
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Takeda
Apnea of Prematurity
Effect of Three-Stair-Position on Improvement of Apnea of Prematurity
The purpose of this study is evaluating the effectiveness of three-stair-position (TSP) on the rate of Apnea of Prematurity (AOP), the feeding performance and the vital signs.
- Trial name
- NCT02346864
- Testing
- Three-stair-position, Head elevated tilt position group
- Volunteers
- 144 people
- Sponsor
- Children's Hospital of Fudan University
Traumatic Brain Injury
Subsymptom Threshold Exercise Protocol Following Mild TBI
The study will monitor outcomes of two interventions to develop a best practice in the treatment of mild Traumatic Brain Injury (mTBI).
- Trial name
- STEP (NCT02267668)
- Testing
- STEP, Control
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University Hospitals Cleveland Medical Center
Spinal Cord Injury (SCI)
Restoring Walking in Non-ambulatory Children With Severe Chronic Spinal Cord Injury (SCI) (Kids STEP Study)
The Kids STEP Study aims to 1. Determine if walking can be restored in children with incomplete SCI and little to no leg movement 2. Identify the neural pathways that permit recovery of walking
- Trial name
- NCT00488280
- Testing
- Locomotor Training
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Florida
Dental Caries Extending Into Dentin
Antibacterial Effect of Light-activated Calcium Silicate Versus Light-activated Calcium Hydroxide
This is a randomized clinical study. 48 subjects with a confirmed diagnosis of deep carious molars without pulpal lesions were randomized to one of two treatments: Patients treated with Light-cured calcium silicate (Theracal)…
- Trial name
- NCT03214770
- Testing
- TheraCal, light-cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Literacy, Parent-Child Relations
Testing an App-Based Approach to Reading and Screen Time Guidance for Parents of Infants
The American Academy of Pediatrics (AAP) recommends that parents read to their children as often as possible beginning in infancy and limits on screen time at all ages, yet many families question the value of reading to infants…
- Conditions
- Literacy, Parent-Child Relations, Language Development
- Trial name
- NCT05508282
- Testing
- Reading Bees app and children's book to enhance parent-infant reading quality (0-2 month visit), Reading Bees app and children's book to encourage alternatives to digital media (6-month visit)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati