Clinical trials: Sting
Cardiomyopathy, Hypertrophic
Long-Term Results of DDD Pacing in Obstructive Hypertrophic Cardiomyopathy
DDD pacing improves symptoms and relieves LV outflow tract (LVOT) obstruction in most patients with hypertrophic cardiomyopathy (HCM).
- Trial name
- NCT00001530
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Scorpion Stings
Severity of Scorpion Sting in Relation to Hematological Parameters
The aim of this study is to investigate the relationship between severity of envenomation and hematological parameter by detectig initial mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio…
- Trial name
- NCT04571411
- Testing
- CBC
- Volunteers
- 100 people
- Sponsor
- Assiut University
Snake Bites
Randomized, Double-Blind, Placebo-Controlled Study: CroFab® vs Placebo for Copperhead Snake Envenomation
This study will evaluate the recovery from copperhead snake bite in patients with mild or moderate venom effect. Potential subjects received CroFab antivenom or placebo.
- Trial name
- Copperhead (NCT01864200)
- Testing
- Crotalidae polyvalent immune fab (ovine)
- Where
- 18 sites in United States
- Volunteers
- 74 people
- Sponsor
- BTG International Inc.
Scorpion Sting Envenomation
Treatment Protocol for Use of Anascorp™ in Patients With Scorpion Sting Envenomation
This treatment protocol will enable therapeutic use of Anascorp in the management of systemic manifestations of scorpion sting envenomation, in patients for whom antivenom would otherwise be unavailable.
- Trial name
- NCT00624078
- Testing
- Antivenin Centruroides (scorpion) F(ab)2 Anascorp™
- Where
- 18 sites in United States
- Volunteers
- 1,426 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Atelectasis, Block
Effect Posterior QLB on Atelectasis
We aimed to investigate the effect of posterior quadratus lumborum block on postoperative atelectasis in inguinal hernia surgery in pediatric patients.
- Conditions
- Atelectasis, Block, Pediatrics, Quadratus Lumborum Block
- Trial name
- NCT04830280
- Testing
- posterior quadratus lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Bronchitis Obstructive, Bronchiolitis; Obstruction
Comparing the Efficacy of Two Valved Holding Chambers in Acute Wheezing
The incidence of physician confirmed asthma is approximately 4-7% in children. An additional 5% of children suffer from infection-related bronchiolitis and obstructive bronchitis.
- Conditions
- Bronchitis Obstructive, Bronchiolitis; Obstruction, Bronchospasm; Bronchitis
- Trial name
- CHAMBER (NCT03900494)
- Testing
- VHC 1, VHC 2
- Where
- 4 sites in Finland
- Volunteers
- 80 people
- Sponsor
- Tampere University
Complex Congenital Heart Defect, Dysfunctional RVOT Conduit
COMPASSION S3 Post-Approval Study
This study will monitor device performance and outcomes of the SAPIEN 3 Transcatheter Heart Valve (THV) System in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted surgical valve…
- Conditions
- Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency, Pulmonary Valve Degeneration
- Trial name
- NCT04860765
- Testing
- SAPIEN 3 THV
- Where
- 19 sites in United States
- Volunteers
- 150 people
- Sponsor
- Edwards Lifesciences
Transversus Abdominis Plane (TAP) Block
IV Sedation Plus TAP Block for Placement of Percutaneous Endoscopic Gastrostomy Tube
Objective: To determine the effectiveness and safety of IV sedation combined with ultrasound-guided, left side transversus abdominis plane (TAP) block versus combination with local anesthetic (LA) infiltration for Percutaneous…
- Trial name
- NCT04878926
- Testing
- IV midazolam and propofol-based sedation combined with ultrasound-guided, left side TAP block, IV midazolam and propofol-based sedation with Local Anesthetic infiltration
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Occlusion, Prosthesis Durability
Abutment Analysis of Metallic Denture Frameworks in Mandibular Kenedy Class III Cases
This study is aimed to compare CAD/CAM (digitally fabricated) metallic partial denture frameworks to conventionally fabricated metallic partial denture frameworks in mandibular Kennedy class-III arches in terms of abutment health…
- Trial name
- NCT07215208
- Testing
- CAD/CAM metallic partial denture frameworks, Conventional metallic partial denture frameworks
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Scorpion Sting Envenomation
Double-Blind, Alacramyn® vs. Placebo in Pediatric Patients
There is no FDA approved therapy for the treatment of scorpion envenomation, Centruroides scorpion envenomation produces a pattern of neurotoxicity with a spectrum of severity ranging from trivial to life threatening.
- Trial name
- NCT00685230
- Testing
- Antivenin Centruroides (scorpion) equine immune F(ab)2
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Relapsed Neuroblastoma, Refractory Neuroblastoma
NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab
This is a Phase 1 study with Phase 2 expansion cohort. Phase 1 will assess the safety and tolerability of universal donor TGFβi NK Cell in combination with irinotecan, temozolomide, and dinituximab.
- Trial name
- STING (NCT04211675)
- Testing
- Natural Killer Cells, Temozolomide, Irinotecan
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Nationwide Children's Hospital
Snakebite, Coagulopathy, Consumption
Waveform Analysis In Snakebite Victims With Hematotoxicity
In hematotoxic snakebites, due to the lack of a better alternative, 20 minute whole blood clotting test (20'WBCT) or Clotting time remains the standard test in developing countries even though its reliability and sensitivity has…
- Trial name
- WISH (NCT03859154)
- Where
- India
- Volunteers
- 96 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Scorpion Stings
Management and Outcome of Scorpion Sting in Children
To determine the clinical characteristics of children with scorpion sting and implement guidelines for management of those children and observe the outcome
- Trial name
- NCT06615440
- Testing
- Alpha blocker
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE), Juvenile Dermatomyositis (JDM)
Compassionate Use Protocol for the Treatment of Autoinflammatory Syndromes
The Requesting Physician/Investigator contacts Lilly when, based on their medical opinion, a patient meets the criteria for inclusion in the expanded access program.
- Conditions
- Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE), Juvenile Dermatomyositis (JDM), Stimulator of Interferon Genes (STING)-Associated Vasculopathy With Onset During Infancy (SAVI), Aicardi-Goutières Syndrome (AGS)
- Trial name
- NCT01724580
- Testing
- Baricitinib
- Where
- 3 sites in United States, United Kingdom
- Sponsor
- Eli Lilly and Company
Pulp Disease, Dental, Obturation
Clinical & Radiographic Evaluation of Zinc Oxide-Ozonated Oil as a New Primary Root Canal Filling
Preserving primary teeth is essential for many aspects such as the child's growth and development, esthetic, functional, psychological, and dental arch integrity aspects.
- Conditions
- Pulp Disease, Dental, Obturation, Root Canal Infection
- Trial name
- NCT05633537
- Testing
- pulpectomy procedure and the clinical evaluation, radiographic evaluation
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Snake Envenomation, Invasive Mechanical Ventilation
A Study to Compare Adaptive Support Ventilation vs. Volume Controlled Ventilation for Management of Respiratory Failure in Patients With Neuroparalytic Snake Envenomation
Neuroparalytic snake envenomation results in severe muscle weakness and respiratory failure. Treatment requires administration of anti-snake venom and supportive care in the form of invasive mechanical ventilation.
- Conditions
- Snake Envenomation, Invasive Mechanical Ventilation, Adaptive Support Ventilation
- Trial name
- ASV vs VCV in (NCT02877498)
- Testing
- Adaptive support ventilation, Volume controlled ventilation
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Insect Bites, Stings
Evaluation of Zapperclick Device for Relief From Mosquito Bites
Mosquito bites commonly result in redness, swelling and itching. This study will determine if a device that emits a small piezo-electrical impulse can provide relief from these symptoms.
- Trial name
- NCT00825214
- Testing
- Zapperclick, Inactivated zapperclick device
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Dental Caries, Dental Occlusion
Occlusal Changes After Modified Hall Technique in Molars Affected by Molar-Incisor Hypomineralization
Molar-incisor hypomineralization (MIH) frequently affects permanent first molars and increases the risk of rapid post-eruptive breakdown and restorative failure.
- Conditions
- Dental Caries, Dental Occlusion, Pediatric Dentistry
- Trial name
- NCT07530835
- Testing
- Modified Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Arachnidism, Latrodectism
The Efficacy and Safety of Aracmyn in Patients With Systemic Latrodectism
The purpose of this study is to compare the safety and effectiveness of an investigational antivenom and the current standard of care (pain management with opioid analgesics) for treating patients with a widow spider bite.
- Trial name
- NCT00247078
- Testing
- widow spider antivenom
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Venom Allergy
Maintenance Bee-Venom Immunotherapy Administered at 6-Month Intervals Does Not Protect Against re-Stings
Maintenance venom immunotherapy administered at 6-month intervals to bee-venom allergic patients failed to provide protection from systemic reactions after sting challenges.
- Trial name
- NCT00684476
- Testing
- venom immunotherapy
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center