Clinical trials: Streptococcus Mutans
Dental Caries and Streptococcus Mutans Count
Impact of Maternal Xylitol Consumption on Mutans Sterptococci
The study was designed to determine whether maternal xylitol consumption through regular chewing of xylitol gums can affect the salivary mutans streptococci (MS), dental caries, and dental plaque levels of their children.
- Trial name
- NCT02036151
- Testing
- xylitol, fluoride varnish application
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Orthodontic Appliance Complication, Lactobacillus Infection
SPACE MAINTAINERS EFFECTS ON ORAL MİCROFLORA
Space maintainers are used to preserve the space after premature loss of teeth but they could effect some factors that play a role in caries formation.
- Conditions
- Orthodontic Appliance Complication, Lactobacillus Infection, Dental Caries in Children, Streptococcus, Other Specified Group
- Trial name
- NCT04749654
- Testing
- The Salivary pH measured, The saliva flow rate was measured, Streptococcus mutans and Lactobacillus counts in saliva were measured
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Cariostatic Agents, Mouthwashes
Anticaries Effect of Xylitol,Probiotic and Chlorhexidine Mouth Rinses Among Individuals at High Risk
Dental caries is a localized, post eruptive pathological process involving softening of the hard tooth tissue and proceeding to the formation of cavity.
- Trial name
- AEXPC (NCT04399161)
- Testing
- Chlorhexidine mouthwash, Xylitol, Probiotic
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Dr. Krupa NC
Malocclusion, Orthodontic Appliance Complication
Microbiological and Epithelial Evaluation Related to the Use of Orthodontic Thermoplastic Device
Thermoplastic devices are used in orthodontic treatment and consists of a series of nearly invisible, removable aligners. However, every device used in the mouth can change the buccal flora and increase the number of bacterias.
- Trial name
- NCT02427763
- Testing
- hours of use (Essix), collect saliva, collect biofilm
- Where
- Brazil
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universidade Positivo
Dental Caries
Effect of Probiotic Drink on Number of Salivary Mutans Streptococci in School Going Children
This study was conducted to assess the effects of commercially available probiotic drink on the number of salivary mutans streptococci in school going children, aged 12-14 years in Bangalore city in India
- Trial name
- NCT01943123
- Testing
- probiotic drink
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Oxford Dental College, Hospital and Research Center, Bangalore, India
Streptococcus Mutans Count, Salivary pH
Clinical Performance, Streptococcus Mutans Count, and Salivary pH for Cention-N, Zirconomer, and Resin-modified Glass Ionomer in Class I Restoration of Primary Molars
This study will evaluate the clinical performance, Streptococcus mutans count, and salivary pH for Cention-N, Zirconomer, and resin-modified glass ionomer in Class I restoration of primary molars.
- Conditions
- Streptococcus Mutans Count, Salivary pH, Cention-N, Zirconomer
- Trial name
- NCT07776912
- Testing
- Cention-N, Zirconomer, Resin-Modified Glass Ionomer
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Galal Ali Mohamed Ebaid
Dental Caries Prevention
Silver Nanoparticle vs Chlorhexidine Mouthwashes for Reducing Streptococcus Mutans and Improving Salivary pH in Children
Dental caries remains one of the most common chronic diseases in children, with Streptococcus mutans playing a major role in its development.
- Trial name
- SMILE (NCT07728409)
- Testing
- Silver nanoparticle mouthwash (10 ppm), Chlorhexidine mouthwash (0.2%)
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Assiut University
Dental Caries, Streptococcus Mutans
Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed Orthodontics
Background This study is part of a doctoral research project at Universidad Cardenal Herrera CEU (Spain), directed by Prof. Santiago Arias de Luxán and conducted by doctoral candidate Shirli Kelmendi within the PhD program in…
- Conditions
- Dental Caries, Streptococcus Mutans, Tooth Demineralization, Orthodontic Appliances, Fixed
- Trial name
- MIPASTEORTHO (NCT07244991)
- Testing
- MI Paste Plus (CPP-ACP with Sodium Fluoride)
- Where
- 2 sites in Albania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Early Childhood Caries
The Anticariogenic Effect of Silver Diamine Fluoride and Sodium Fluoride Varnish
Sodium Fluoride (NAF) varnish was considered as the treatment of Early Childhood Caries (ECC). However, the emergence of Silver Diamine Fluoride (SDF) has become more popular to tackle dental caries among children.
- Trial name
- NCT06316323
- Testing
- Silver diamine fluoride, Sodium fluoride
- Where
- Malaysia
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
Dental Caries
Er,Cr:YSGG Laser Versus Conventional Preparation for Minimally Invasive Caries Removal
This study compared two standard methods for minimally invasive caries removal in children: conventional mechanical excavation and Er,Cr:YSGG laser preparation.
- Trial name
- NCT07493278
- Testing
- Mechanical Caries Removal, Er,Cr:YSGG Laser Caries Removal
- Where
- Bulgaria
- Volunteers
- 32 people
- Sponsor
- Medical University of Sofia
Streptococcal Infections, Saliva Altered
Efficacy of Propolis Varnish Against Oral Biofilm
This study aims to evaluate the effectiveness of a varnish containing 15% of green propolis on Streptococcus mutans in saliva and biofilm.
- Trial name
- NCT02052973
- Testing
- Propolis varnish
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Probiotic, Ethyl Lauroyl Arginate
Probiotic-Based Versus Ethyl Lauroyl Arginate-Containing Mouthwashes on Streptococcus Mutans Counts, Dental Plaque Accumulation, and Salivary pH in a Group of Egyptian School Children
This study aims to compare the efficacy of probiotic-based mouthwashes versus ethyl lauroyl arginate-containing mouthwashes in reducing Streptococcus mutans count, dental plaque accumulation, and salivary pH among a group of…
- Conditions
- Probiotic, Ethyl Lauroyl Arginate, Mouthwashes, Streptococcus Mutans
- Trial name
- NCT07356869
- Testing
- Probiotic mouthwash, Ethyl lauroyl arginate mouthwash, Professional prophylaxis (scaling + polishing)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Al-Azhar University
Mutans Streptococci, Oral Health
Antimicrobial Effect of Different Pastes on Streptococcus Mutans in Children
This study is a randomized controlled trial involving 127 children ages between 4 and 5 years to investigate the efficacy of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) in reducing Streptococcus mutans (S.
- Trial name
- NCT03526315
- Testing
- CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP)
- Where
- Jordan
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Topical Fluoride, Orthodontic Patients
Effects of Topical Fluoride in Orthodontic Patients
This study was born from the need to improve caries prevention in orthodontic patients, a group particularly at risk. Fixed orthodontic appliances make daily oral hygiene more difficult, leading to increased plaque accumulation…
- Conditions
- Topical Fluoride, Orthodontic Patients, Antimicrobial Effect, Clinical Effect
- Trial name
- NCT07091890
- Testing
- Fluoride gel, Fluoride varnish
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Dental Caries
Effectiveness of Coconut Oil Pulling With Clove Oil, Coconut Oil Pulling and Fluoride Mouthwash on Streptococcus Mutans Count in Children
This study aims to compare the effectiveness of coconut oil pulling with clove oil, coconut oil pulling alone, and fluoride mouthwash in reducing Streptococcus mutans levels in children aged 6-12 years.
- Trial name
- COPCO (NCT06902532)
- Testing
- coconut oil pulling with clove oil, coconut oil pulling, Fluoride Mouthwash
- Where
- 2 sites in Egypt
- Volunteers
- 105 people
- Sponsor
- Cairo University
Asthma, Dental Caries
Herbal Lollipops on Oral Bacterial Levels and DMFT/Dmft Scores of Children With Asthma Using Inhalers
Young children with asthma who use drugs for their asthma are at higher risk for tooth decay. These drugs can cause (1) dry mouth from less saliva secretion and (2) acid mouth that causes teeth to become soft and bacteria to…
- Trial name
- Lollipops (NCT01147835)
- Testing
- Chinese Licorice Root
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Tooth Decay, Probiotics
Effects of Probiotics on Streptococcus Mutans ve Lactobacillus Spp
To evaluate the change of S. mutans and Lactobacillus spp. counts after all dental treatments were completed under general anesthesia and compare the groups in case of using probiotics and not using probiotics with the time for…
- Conditions
- Tooth Decay, Probiotics, Streptococcus Mutans
- Trial name
- NCT05859646
- Testing
- Probiotic use
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Didem Sakaryali Uyar