Clinical trials: Streptococcus Mutans
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
Caries
Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste
Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica', the famous 'Toothbrush Tree' used for centuries.
- Trial name
- NCT05109299
- Testing
- Miswak toothpaste, Fluoride toothpaste
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Streptococcus, Other Specified Group, Dental Plaque
Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans
Papaya has effects on oral pathogenic microorganisms, it also has anticoagulant quality, amebicidal action, antimicrobial, bacteriostatic and antifungal activity on different bacteria, especially on Streptococcus mutans, this can…
- Trial name
- NCT04485520
- Testing
- CARICA PAPAYA MOUTHWASH, CHLORHEXIDINE MOUTHWASH
- Where
- Paraguay
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Julieta María Méndez Romero
Dental Caries
The Microbiology of Caries Resistance
The purpose of this research study is to investigate the bacterial composition of plaque and saliva located in the mouth and associate that with risk factors that cause cavities.
- Trial name
- NCT02130206
- Testing
- Caries Free, Caries Active
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Florida
Geriatric Patients
Antibacterial Effect of Probiotic Yogurt Compared to Xylitol
This study will be conducted to evaluate the antibacterial effect of probiotic bacteria in yogurt in decreasing streptococcus mutans count in saliva and plaque, decreasing bacterial adherence and increasing salivary pH compared…
- Trial name
- NCT03889015
- Testing
- Probiotic yogurt, xylitol chewing gum
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy
Effect of Atraumatic Restorative Treatment on Streptococcus Mutans Count in Saliva of Pregnant Women
S. mutans counts have been found to be high in women with high level of untreated caries. In Pakistan 95% of all carious lesions are untreated that is an alarming situation.
- Trial name
- ART (NCT01655732)
- Testing
- Atraumatic Restorative Treatment
- Where
- Pakistan
- Volunteers
- 94 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Dental Caries, Streptococcal Infections
Evaluation of Efficacy of Antibacterial Activity of Licorice, Clove, and Chlorohexidine Mouthwashes on Salivary Streptococcus Mutans in a Group of Egyptian Children.
A randomized controlled trial that compares the antibacterial effectiveness of three mouthwashes-licorice, clove, and chlorhexidine-in Egyptian children aged 7-12 years.
- Conditions
- Dental Caries, Streptococcal Infections, Mouthwashes
- Trial name
- NCT07828171
- Testing
- Mouth wash
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- British University In Egypt
Dental Caries
EFFICACY OF MORUS ALBA FRUIT EXTRACTS AND CHLORHEXIDINE ON SALIVARY STREPTOCOCCUS MUTANS AND pH LEVELS
Dental caries is highly prevalent across the globe including Pakistan and is associated with tooth loss, malocclusion and temporomandibular joint problems and sometimes may cause life threatening infections.
- Trial name
- NCT05052775
- Testing
- Chlorhexidine Mouthwash, Morus Alba 20%, Morus Alba 30%
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Ziauddin University
Dental Plaque, Dental Caries
Novamin on Streptococcus Mutans Count in Dental Plaque of High Caries Risk Children
Inhibition of streptococcus mutans can be effective to prevent caries in high caries-risk children. The aim of the study is to evaluate the effect of Novamin on streptococcus mutans in the plaque of high caries-risk children.
- Trial name
- NCT05979636
- Testing
- Novamin containing toothpaste, Fluoride containing toothpaste
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Hams Hamed Abdelrahman
Dental Caries
Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction
This study compared four mouth rinses/chews for their ability to reduce Streptococcus Mutans after usage. The four that were compared were chlorhexidine gluconate (0.12%), sodium fluoride (0.05%), paraffin wax chewing gum (sugar…
- Trial name
- NCT02598778
- Testing
- Chlorhexidine gluconate (0.12%), Sodium Fluoride (0.05%), Paraffin wax chewing gum (sugar-free)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Dental Caries
Evaluation of the Antibacterial Effect of Laser Diode and Zinc Oxide Nano Particles in Cavity Disinfection
this is a randomized controlled clinical trial, evaluating the antibacterial effect of laser diode and zinc oxide nano-particles when used as cavity disinfectants.Two groups, including 15 patients each, will be randomly allocated…
- Trial name
- NCT03478150
- Testing
- zinc oxide nano-particles, laser diode
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Streptococcus Mutans, High Caries Risk Patients
Streptococcus Mutans Cariogenicity by Real-time PCR in High Caries Risk Patients
In patients with high caries risk, will the use of cinnamon extract or chlorohexidine based mouthwashes have an effect on the percentage of recovery and cariogenicity of Streptococcus mutans (SM) detected by real-time Polymerase…
- Trial name
- NCT04566120
- Testing
- cinnamon extract mouthwash, chlorohexidine based mouthwash
- Where
- Egypt
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Alkaline Water and Salivary Bacterial Count
This study will be aimed to examine the effect of alkaline water on salivary streptococcus mutans bacteria which is the main cause of dental caries and comparing its effect with chlorohexidine mouthwash on the children aged…
- Trial name
- NCT06511336
- Testing
- Alkaline water (FLO water- Bottled drinking water- the Egyption Saudi Company for natural water- made in Egypt
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Healthy
Effect of Sustained-Release Cetylpyridinium Chloride Varnish on Streptococcus Mutans and Lactobacillus in Orthodontic Patients
The purpose of the study is to was to evaluate the anti bacterial efficacy of sustain-release Cetylpyridinium chloride varnish on orthodontic patients.
- Trial name
- NCT00416286
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Caries
SDF vs Fluoride Varnish for Streptococcus Mutans Reduction in Children
This randomized split-mouth clinical trial will compare the effectiveness of 38% silver diamine fluoride (SDF) versus 5% sodium fluoride varnish (FV) in reducing salivary Streptococcus mutans levels in children with bilateral…
- Trial name
- Streptococcus (NCT07181967)
- Testing
- Sodium Fluoride Varnish (5%), Silver Diamine Fluoride (38%)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
Caries,Dental, Caries Active
Anticariogenic Properties of Zamzam Water
The present study aims to evaluate and compare the effect of Zamzam water as mouthwashes in high caries-risk patients regarding: i. Streptococcus mutans (S. mutans) count. ii. Oral pH. After 3 and 6 months interval.
- Trial name
- NCT06538532
- Testing
- Zamzam water
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Comparison of the Salivary Levels of Streptococcus Mutans in Pediatric Patients With Early Childhood Caries After the Application of Silver Diamine Fluoride or 5% Sodium Fluoride Varnish
Comparison of the salivary levels of Streptococcus mutans in pediatric patients with Early Childhood Caries after the application of Silver Diamine Fluoride or 5% Sodium Fluoride Varnish
- Trial name
- NCT03089567
- Testing
- Sodium Fluoride, Silver diamine fluoride
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Dental Plaque, Saliva Altered
Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables
The purpose of this study is to determine the effect of three times a day mastication, during a follow-up period of 4 weeks, of two sugar-substituted chewing gums on various factors associated with dental caries and gingivitis.
- Conditions
- Dental Plaque, Saliva Altered, Gingivitis
- Trial name
- NCT01578603
- Testing
- xylitol, casein phosphopeptide amorphous calcium phosphate complex
- Where
- Colombia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Plaque Control
Triphala Tooth Wipes in Reduction of Streptococcus Mutans Colonies
This double-blind randomized clinical trial will be conducted among differently abled institutionalized children. Sixty participants aged 6-12 years with mild intellectual disability (ID) will be enrolled in the study and divided…
- Trial name
- NCT06575335
- Testing
- Triphala Tooth Wipe, Chlorhexidine Tooth Wipe
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Oral Hygiene
Orodental Hygiene in Children With Special Needs
This clinical trial aims to learn about the general oral hygiene status of children with special needs and test the effect of hygiene education on their oral and dental hygiene.
- Trial name
- NCT05697432
- Testing
- Oral Examination, PUFA index, Plaque index
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Altinbas University