Clinical trials: Study Adherence
HIV/AIDS
Youth Engagement Study: Intervention to Increase HIV Treatment Engagement and Adherence for Young People Living With HIV
This pragmatic adaptive clinical trial will test the effects of a Stigma-Motivational-Decision intervention designed to increase HIV treatment engagement, retention, and medication adherence for substance using adolescents and…
- Trial name
- YES (NCT03665532)
- Testing
- Youth Engagement in Services
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Connecticut
Obstructive Sleep Apnea, Hypoventilation
The IPAd Study: Exploring the Association Between Insomnia and Positive Airway Pressure Adherence in Children
Sleep-disordered breathing (SDB) is prevalent in children and adolescents and untreated SDB impacts key indicators of physical and psychosocial health.
- Conditions
- Obstructive Sleep Apnea, Hypoventilation, Central Sleep Apnea
- Trial name
- IPAd (NCT05949164)
- Testing
- Insomnia
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- The Hospital for Sick Children
Hepatitis C, Chronic, Hepatitis C
Adherence to Treatment With PegIntron Pen Plus Rebetol in Treatment-naïve Adult Patients With Hepatitis C in Romania (Study P04247)
Adherence to the prescribed treatment regimen with PegIntron and Rebetol affects the chance of achieving a sustained virologic response in patients with hepatitis C.
- Trial name
- NCT00705107
- Testing
- PegIntron pen (peginterferon alfa-2b; SCH 54031), Rebetol (ribavirin; SCH 18908)
- Volunteers
- 267 people
- Sponsor
- Merck Sharp & Dohme LLC
Autism, Treatment Adherence
A Clinical Study Evaluating the Efficacy and Safety of Retinoic Acid in Patients With 15q11-q13 Duplication Syndrome
Autism Spectrum Disorders (ASD), with its core symptoms of communication and repetitive behaviors, is a serious neurodevelopmental disorder common in childhood and affects about 1% of children.
- Conditions
- Autism, Treatment Adherence, Retinoic Acid, Dup15Q Syndrome
- Trial name
- NCT05281965
- Testing
- Retinoic acid
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Sickle Cell Disease
ElectroNic Hydroxyurea AdhereNCE: A Strategy to Improve Hydroxyurea Adherence in Patients With Sickle Cell Disease
HU is an FDA approved medication for the treatment of SCD. Many studies have shown that HU can reduce SCD related symptoms, but only 50% of patients take it as often as they should.
- Trial name
- ENHANCE (NCT02578017)
- Testing
- Mobile DOT
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Nationwide Children's Hospital
Health Care Transition Readiness, Health Literacy
Health Care Transition Readiness Short-Form Video Intervention
The goal of this clinical trial is to assess whether social-media style short-form health education videos can increase health care transition readiness, self-efficacy, emotional well-being, health literacy, and appointment…
- Conditions
- Health Care Transition Readiness, Health Literacy, Self Efficacy, Emotional Wellbeing
- Trial name
- NCT06842576
- Testing
- Health Education Videos, GotTransition.org Website
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Children's Hospital Los Angeles
Human Immunodeficiency Virus, Mental Disorder
Integrated Mental Health Care for Pregnant Women With HIV in Kenya: The Tunawiri Study
This study seeks to improve mental health, pregnancy, and HIV outcomes among pregnant and postpartum women living with HIV with common mental health disorders in Kenya.
- Trial name
- NCT06117163
- Testing
- Collaborative Care Model
- Where
- Kenya
- Volunteers
- 900 people
- Sponsor
- University of Colorado, Denver
Type 1 Diabetes Mellitus
Continuous Glucose Monitor in Children With Poorly Controlled Diabetes
The purpose of this study is to determine if the use of continuous glucose monitoring in a practical outpatient clinic setting in children with poorly controlled diabetes will lead to improved blood sugar control.
- Trial name
- NCT02530450
- Testing
- continuous glucose monitoring (CGM)
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Adolescence Idiopathic Scoliosis, AIS
Smartphone App for Adolescents With Idiopathic Scoliosis
This study aims to evaluate a smartphone application (DinSkoliose) designed to support adolescents with idiopathic scoliosis (AIS) in managing their condition and following their treatment.
- Trial name
- NCT07686848
- Testing
- DinSkoliose smartphone application
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Oslo Metropolitan University
Respiratory Tract Infections
Compliance And Safety Study In Children With Upper And Lower Respiratory Tract Infections
The objective of this study was to obtain data on the safety, tolerability and compliance with Zithromax in children with bacterial infections of the upper and lower respiratory tract.
- Trial name
- COMPAS (NCT00939185)
- Testing
- Azithromycin
- Volunteers
- 400 people
- Sponsor
- Pfizer
Vitamin D Deficiency
Community Interventional Trial (CITFOMIST)
The cluster randomized trial (CITFOMIST) was conducted on 15-19-year old guidance and high school students of both genders from different districts of Tehran, the Iranian capital, in winter 2011.
- Trial name
- CITFOMIST (NCT02035423)
- Testing
- 120 IU milk, 200 IU Milk, Non-Fortified Milk
- Where
- Iran
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Celiac Disease in Children
Dietary Intervention Using a Gluten-free App to Improve Tracking, Adherence, and Learning(DIGITAL) Study
With rising incidence of celiac disease(CeD) (3% of population), there is an urgent need for practical, efficient and usable application that can feedback to families and providers about their ultra-processed gluten-free food…
- Trial name
- DIGITAL (NCT07192874)
- Testing
- MyMedDiary, Feedback on Gluten Exposure
- Volunteers
- 120 people
- Sponsor
- Boston Children's Hospital
Dental Caries, Compliance Behavior
Treatment of Initial Caries Lesions on Proximal Surfaces of Primary and Permanent Posterior Teeth
This study aims to evaluate the effectiveness of 30% silver diamine fluoride in the treatment of clinically caries lesions in enamel, with radiographic image restricted to the enamel or the outer third of dentin on the proximal…
- Trial name
- NCT01477385
- Testing
- Resin Infiltration, 30% Silver Diammine Fluoride, Dental Flossing
- Where
- Brazil
- Volunteers
- 183 people
- Sponsor
- University of Sao Paulo
Kidney Transplant
Natural History Study of Azathioprine Adherence
This study began in 1993 as a prospective, natural history study of renal transplant patients' medication compliance measured by using an electronic monitor on the cap of medication vials.
- Trial name
- NCT00143910
- Testing
- observation
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Thomas E. Nivens, MD
Procedural Related Injuries and Complications Nec, Patient Satisfaction
Radial Versus Femoral Arterial Access for Cerebral Angiography in Adolescents
This study will compare radial vs femoral access for angiography in adolescents. Neuroangiography and neurointerventions are predominantly performed via femoral access, which has several limitations and complications - pain and…
- Trial name
- NCT04604340
- Testing
- transradial access for neuroangiography, transfemoral access for neuroangiography
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- The Hospital for Sick Children
Urinary Tract Infections, Communication
Communication and Compliance for Antibiotic Prescribing by General Practice to Nursing Home Residents With Suspected UTI
Antibiotic resistance is becoming a bigger problem. If the problem remains unsolved, the WHO predicts a return to the pre-antibiotic era.
- Conditions
- Urinary Tract Infections, Communication, Compliance, Medication
- Trial name
- NCT03700060
- Where
- Denmark
- Volunteers
- 459 people
- Sponsor
- Research Unit Of General Practice, Copenhagen
Tyrosinemias, Alkaptonuria
Evaluation of TYR Sphere
For 28 days, 20 patients with tyrosinaemia will take TYR sphere as part of the usual dietary management of their condition. Patients will record their adherence to recommended intakes each day, gastrointestinal symptoms (if any)…
- Conditions
- Tyrosinemias, Alkaptonuria, Tyrosinemia, Type I, Tyrosinemia, Type II
- Trial name
- NCT04196959
- Testing
- TYR sphere
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- Vitaflo International, Ltd
Growth Disorders
To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Middle East
This is a Middle East, Multicenter, Observational Study to evaluate Adherence and Long Term Outcomes of Therapy in pediatric subjects using easypod™ electromechanical device for growth hormone treatment and to assess the level of…
- Trial name
- ECOS UAE (NCT02015286)
- Testing
- easypod™
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Disabilities, Type 2 Diabetes
The Impact of Medication Adherence in Patients With Type 2 Diabetes and Disabilities
Individuals with disabilities and type 2 diabetes tend to have worse clinical outcomes. To identify modifiable factors that may improve these outcomes, the investigators evaluated the role of medication adherence.
- Trial name
- NCT07052708
- Testing
- No adherence group, Adherence group
- Volunteers
- 365,295 people
- Sponsor
- Samsung Medical Center
Infantile Spasms
Acceptability Study of a New Paediatric Form of Vigabatrin in Infants and Children With Infantile Spasms or Pharmacoresistant Partial Epilepsy
The sponsor is developing a new paediatric formulation of vigabatrin to better adjust the dose to body weight and to limit waste of unused drug.
- Trial name
- SoluWest (NCT02220114)
- Testing
- Vigabatrin: Vigabatrin new ST formulation then Sabril®
- Where
- 12 sites in France
- Volunteers
- 38 people
- Sponsor
- Orphelia Pharma