Clinical trials: Subdural Hematoma
Paraganglioma, Pheochromocytoma
Hereditary Paraganglioma: Evaluation of Screening Methods to Detect Tumors in SDH Positive Carriers
Hereditary paraganglioma -due to SDH (SDHD, SDHB, SDHC) germline mutations- causes paragangliomas and pheochromocytomas. Presymptomatic genetic testing should be offered to all first-degree relatives if an SDH mutation is…
- Trial name
- NCT00188019
- Testing
- diagnosis methods
- Where
- France
- Volunteers
- 248 people
- Sponsor
- University Hospital, Angers
Diabetes Mellitus
ASCEND: ApproacheS to CHC ImplEmeNtation of SDH Data Collection and Action
This work will test a set of strategies for helping community health centers (CHCs) routinely identify and take action on the SDH-related needs of patients with / at risk for DM using a stakeholder-driven process to develop…
- Trial name
- ASCEND (NCT03607617)
- Testing
- SDH Tool
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Traumatic Brain Injury, Subarachnoid Hemorrhage
Comparison of Narcotrend and Cerebral Function Analysing Monitor in Intensive Care to Monitor Seizures and Deep Sedation
A study in the use of the Narcotrend depth of anaesthesia monitor to record a) seizures, and b) monitor a level of sedation referred to as 'burst suppression', in sedated patients in the adult and paediatric intensive care.
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Haemorrhage, Encephalitis
- Trial name
- NCT06067750
- Testing
- Narcotrend compared to Cerebral Function Analysing Monitor (CFAM)
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Hematoma, Subdural Hematoma
Patient Registry for Patients With Chronic Subdural Hematoma
All admitted patients diagnosed with unilateral or bilateral chronic subdural hematoma are included into this registry after consent.
- Conditions
- Hematoma, Subdural Hematoma, Chronic
- Trial name
- CSDH-R (NCT04170582)
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Head Trauma, Craniocerebral Injuries
Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas
The goal of this study is to determine the sensitivity, specificity, and positive and negative predictive values of the a portable near-infrared-based device (portable NIR-based device), the InfraScanner 2000™, to detect…
- Conditions
- Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries
- Trial name
- NCT03353246
- Testing
- InfraScanner 2000™
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Duke University
Human Papilloma Virus
SDH of HPV Vaccine Completion
The purpose of this research study is to find out which factors influence parents' ability to complete the human papillomavirus (HPV) vaccine series for their child.
- Trial name
- NCT03709602
- Where
- United States
- Volunteers
- 3,076 people
- Sponsor
- Duke University
Acute Brain Injury
The NEUROlogically-impaired Extubation Timing Trial (NEURO-ETT)
This trial in brain-injured patients will test which of the following will lead to better patient outcomes: (1) an airway management pathway consisting of daily assessments and removal of the breathing tube as soon as patients…
- Trial name
- NCT04291235
- Testing
- Airway Management Pathway, Usual Care
- Where
- 14 sites in Canada
- Volunteers
- 332 people
- Sponsor
- Sunnybrook Health Sciences Centre
Tbi, Intracranial Edema
Comparative Effectiveness of Family Problem-Solving Therapy (F-PST) for Adolescent TBI
Traumatic brain injury (TBI) is the most common cause of acquired disability in youth and a source of significant morbidity and family burden.
- Conditions
- Tbi, Intracranial Edema, Brain Edema, Craniocerebral Trauma
- Trial name
- NCT02368366
- Testing
- Therapist Guided Face to Face Family Problem Solving, Therapist Guided Online Family Problem Solving, Self-Guided Online Family Problem Solving
- Where
- 5 sites in United States
- Volunteers
- 151 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Traumatic Brain Injury (TBI), Attention Deficit Hyperactivity Disorder (ADHD)
Attention Intervention Management
This is a research study to learn if a computer-based intervention that provides direct attention and metacognitive strategy development can improve attention, memory, and executive control in adolescents with moderate-to-severe…
- Conditions
- Traumatic Brain Injury (TBI), Attention Deficit Hyperactivity Disorder (ADHD), Head Injury, Brain Concussion
- Trial name
- AIM (NCT01779427)
- Testing
- AIM
- Where
- United States
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Traumatic Brain Injury
Internet-Based Treatment for Children With Traumatic Brain Injuries & Their Families: Counselor Assisted Problem Solving
This study will evaluate the effectiveness of an Internet-based psychosocial treatment in improving problem-solving, communication skills, stress management strategies, and coping among children who have had a traumatic brain…
- Trial name
- CAPS (NCT00409448)
- Testing
- Counselor-assisted problem solving (CAPS), Internet-resource comparison (IRC)
- Where
- 5 sites in United States
- Volunteers
- 132 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Subdural Hematoma
Low Intracranial Pressure Treatment Strategies for Chronic Subdural Hematoma Patients
The proportion of the elderly population is increasing rapidly. Chronic subdural hematoma has become the most common cause of surgery in neurosurgery for elderly patients. The standard treatment for cSDH is mostly surgery.
- Trial name
- CSDH-LP (NCT04607447)
- Testing
- low intracranial pressure strategy treatment, Atorvastatin plus Dexamethasone
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Huashan Hospital
Traumatic Brain Injury
Interacting Together Everyday: Recovery After Childhood Traumatic Brain Injury (TBI) "I-InTERACT
The purpose of this study is to test an on-line intervention for families of young children who have experienced moderate or severe traumatic brain injury (TBI).
- Trial name
- I-InTERACT (NCT01056146)
- Testing
- Internet-based Interacting Together Everyday: Recovery After Childhood TBI, Internet Resources Comparison
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Paraganglioma, Gastrointestinal Stromal Tumors
A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer
Background: Wild-type gastrointestinal stromal tumor (GIST) is a cancer in the esophagus, stomach, or intestines. It does not respond well to standard chemotherapy or radiation therapy.
- Conditions
- Paraganglioma, Gastrointestinal Stromal Tumors, Carcinoma, Renal Cell, Renal Neoplasms
- Trial name
- NCT03165721
- Testing
- SGI-110 (guadecitabine)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Cancer Institute (NCI)
Traumatic Brain Injury
Rehabilitation Research and Training Center for Traumatic Brain Injury Interventions--Teen Online Problem Solving Study
This study will evaluate the effectiveness of an Internet-based psychosocial treatment in improving problem-solving, communication skills, stress management strategies, and coping among teens who have had a traumatic brain injury…
- Trial name
- RRTC--TOPS (NCT01042899)
- Testing
- Teen Online Problem Solving (TOPS), Teen Online Problem Solving--Teen Only (TOPS-TO), Internet Resources Comparison (IRC)
- Where
- 5 sites in United States
- Volunteers
- 153 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Gastrointenstinal Stromal Tumor (GIST), GIST - Gastrointestinal Stromal Tumor
A Comprehensive, Multinational GIST Registry
Patients diagnosed with a gastrointestinal stromal tumor (GIST), a rare type of tumor in the digestive tractparticipate in this scientific research study, known as a registry study, to help improve understanding and treatment of…
- Trial name
- reGISTTry (NCT07273045)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Universität Duisburg-Essen
Acute Subdural Hematoma
Scandinavian Multicentre Acute Subdural Hematoma (SMASH) Study
In a multi-national population-based cohort, the investigators want to compare the clinical course and clinical outcome of elderly patients (≥70 y/o) compared with younger patients (< 70 y/o) with acute subdural hematoma treated…
- Trial name
- SMASH (NCT03284190)
- Testing
- Surgery
- Volunteers
- 1,600 people
- Sponsor
- Karolinska University Hospital
Pelvic Fracture, Prostate Cancer
A COhort Study on Factors Leading to Vulnerability in Adult Patients With Serious Medical cOnditionS: the COSMOS-I Trial
The objective of this prospective multicentre study that recruits altogether 1500 older patients from the university hospitals of Tampere, Kuopio, and Oulu is to explore the clinical significance and detection of causes of…
- Conditions
- Pelvic Fracture, Prostate Cancer, Lung Cancer, Brain Metastasis
- Trial name
- COSMOS-I (NCT07740239)
- Testing
- Test set to determine vulnerability
- Where
- Finland
- Volunteers
- 2,050 people
- Sponsor
- Tampere University Hospital
TBI (Traumatic Brain Injury), Brain Edema
Teen Online Problem Solving (TOPS) - An Online Intervention Following TBI
The purpose of this study is to learn if using the World Wide Web to train teens and their families in problem-solving, communication skills, and stress management strategies can help them to cope better following traumatic brain…
- Conditions
- TBI (Traumatic Brain Injury), Brain Edema, Craniocerebral Trauma, Hematoma
- Trial name
- TOPS (NCT00409058)
- Testing
- Teen Online Problem Solving
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Traumatic Brain Hemorrhage
Traumatic Acute Subdural Haematoma: Management and Outcome
Traumatic acute subdural haematomas (ASDHs) are common pathological entity in neurosurgical practice . The frequency of (ASDHs) has been proposed as approximately 10-20% of patients admitted with traumatic brain injury(TBI)…
- Trial name
- NCT03971240
- Testing
- evacuation of traumatic acute subdural hematoma
- Volunteers
- 39 people
- Sponsor
- Assiut University
Chronic Non-Traumatic Intracranial Subdural Haemorrhage
Non Traumatic Chronic Subdural Haematoma in Paediatric Age Groups, Management and Outcome
1-Review the management strategies and outcomes in cases of non traumatic chronic subdural haematoma in paediatric age group. 2- Review the underlying causes and risk factors in cases of non traumatic chronic subdural haematoma…
- Trial name
- NCT06743893
- Testing
- Diagnosis and outcome of non traumatic chronic subdural haematoma in pediatric age groups
- Volunteers
- 30 people
- Sponsor
- Assiut University