Clinical trials: Suicidal Behaviour
Non-suicidal Self-injury
Effects of taVNS Combined With tACS on Adolescents With Non-Suicidal Self-Injury
NSSI behavior is highly prevalent among adolescents, and its mechanisms are closely associated with attentional bias toward self-injury-related information and impulsivity, both of which may be related to reduced dlPFC activation…
- Trial name
- NCT07486804
- Testing
- 25Hz、300us transcutaneous auricular vagus nerve stimulation and10hz transcranial alternating current stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Suicidal Ideas, Suicidal Ideation
Exploratory Analysis of Interpersonal and Intrapersonal Psychological Processes Implied in Risk-taking and Suicidal Behaviors, in Adult and Adolescent At-risk
In a recent report, Santé Publique France (2023), reported that 4.2% of 18-85 year-olds had thought about suicide in the last 12 months, and 6.8% had attempted suicide in their lifetime and 0.5% in the last year.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Risk-taking
- Trial name
- RISKY (NCT06921226)
- Testing
- Psychological Processes, Risk-taking variables, Suicidal ideation and behavior
- Where
- 3 sites in France
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Anxiety, Suicidal Ideation
Climate Anxiety in a Young Population at Risk of Suicide
Climate change has become a major source of concern, particularly among younger generations who are facing the progressive degradation of ecosystems, loss of biodiversity, and alarming environmental information disseminated…
- Conditions
- Anxiety, Suicidal Ideation, Mental Health Issue, Environmental Exposure
- Trial name
- Anx-RS (NCT07305688)
- Testing
- Columbia Suicide Severity Rating Scale, Climate Change Anxiety Scale - French version, State-Trait Anxiety Inventory, French version
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Centre Hospitalier Esquirol
Suicidal Ideations, Suicidal Behaviors
Technology-assisted Methods to Advance Suicide Prevention Among Youth in Colombia
This study will investigate a multi-level approach that applies technology-assisted methods to reduce suicidal thoughts and behaviors (SIB) and promote mental health among Colombian youth: (a) digital platform for youth; (b)…
- Conditions
- Suicidal Ideations, Suicidal Behaviors, Depression, Anxiety, Well-being
- Trial name
- NCT06651554
- Testing
- Digital Platform Intervention
- Where
- Colombia
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Brown University
Suicide, Mental Health Disorder
Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- NCT06665620
- Testing
- ViraBrite nudges
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ksana Health
Depression, Suicidal Ideation
Screening Wizard, Component 1 of iCHART (Integrated Care to Help At-Risk Teens)-Feasibility/Pilot Phase
Screening Wizard (SW). Primary Care Providers (PCPs) are often uncertain about how to best refer adolescents who screen positive for depression or suicidality.
- Trial name
- NCT03985813
- Testing
- Screening Wizard
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- University of Pittsburgh
Self-harm Behavior, Eating Disorders
Evaluation of National Highly Specialized Care for Children and Adolescents With Severe Self-Harm or Eating Disorders
National Highly Specialized Care (NHV) is provided in Sweden to children and adolescents with severe and treatment-resistant self-harm or eating disorders when previous treatment has not led to sufficient improvement.
- Conditions
- Self-harm Behavior, Eating Disorders, Non-suicidal Self-injury (NSSI)
- Trial name
- NHV_CHILD (NCT07898059)
- Testing
- National Highly Specialized Care (NHV)
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Bipolar Disorder, Suicidal Ideation
Mentalization-Based Therapy to Prevent Suicidal Behavior in Adolescents With Bipolar Disorder
Children and adolescents with early-onset bipolar disorder (BD) are at high risk for intentionally hurting themselves. Although there are therapies in existence for these youths with BD, they do not address suicide prevention…
- Trial name
- NCT02129790
- Testing
- Mentalization-Based Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Suicidal Ideation
SAFETY-A for Promoting Equity in Suicide Prevention Outcomes in Schools
This study will adapt Safe Alternatives For Teens and Youth - Acute (SAFETY-A) for implementation in low-resourced school districts to reduce racial/ethnic disparities in mental health service use (MHS) following identification…
- Trial name
- NCT05834660
- Testing
- Safe Alternatives for Teens and Youth-Acute for Schools (SAFETY-A for Schools)
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- University of California, Los Angeles
Suicide, Adolescent Behavior
Wearable Suicidal Early Warning System for Adolescents
This study is prospectively enrolling a cohort of adolescent patients who present to the Emergency Department and an inpatient psychiatric adolescent unit with acute suicidality.
- Trial name
- NCT03030924
- Testing
- Solace
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Oregon Health and Science University
Suicidal Ideation
Pilot Trial of Mobile Technology for Adolescent Suicidality
The primary objective of this study is to assess the efficacy of a digital intervention in reducing suicidal ideation in adolescents.
- Trial name
- NCT06454136
- Testing
- OTX-207, Comparator App + Treatment as Usual (TAU)
- Where
- 3 sites in United States
- Volunteers
- 228 people
- Sponsor
- Oui Therapeutics, Inc.
Suicidal Ideation
Circles of Hope: Group Intervention for Adolescents With Suicidal Symptoms
This pilot study examines the feasibility, acceptability, and preliminary outcomes of a short-term group psychotherapy intervention for adolescents experiencing suicidal symptoms without immediate suicidal intent.
- Trial name
- COH (NCT07818863)
- Testing
- Circles of Hope Group Psychotherapy
- Volunteers
- 40 people
- Sponsor
- University of Haifa
Borderline Personality Disorder, Suicide and Self-harm
Trial of a Brief Psychological Intervention for Suicidal Patients with Borderline Personality Disorder in the Emergency Department
When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour.
- Trial name
- NCT04779099
- Testing
- Brief 4-session intervention for borderline personality disorder, Treatment as usual
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health
Suicidal Ideation, Suicidal Ideas
Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation
Approximately 20% of Canadian adolescents experience thoughts of suicide, or suicidal ideation (SI), and suicide is the second leading cause of death among Canadians aged 15-19 years.
- Trial name
- KSI (NCT06366334)
- Testing
- Ketamine Hydrochloride, Normal saline
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Eastern Ontario
Non Suicidal Self Injury, Suicidal Ideation
aiTBS for NSSI and Suicide in Adolescent Depression
Repetitive transcranial magnetic stimulation (rTMS) has been successfully used to help patients with treatment resistant depression.
- Conditions
- Non Suicidal Self Injury, Suicidal Ideation, Suicide and Self-harm
- Trial name
- NCT06210100
- Testing
- Active iTBS
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Central South University
Self-Injurious Behavior, Suicidal Ideation
Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization
Suicide is the 2nd leading cause of death among adolescents, with the highest risk period for suicide being the month following psychiatric inpatient hospitalization.
- Conditions
- Self-Injurious Behavior, Suicidal Ideation, Suicide Attempts
- Trial name
- TEC (NCT05796531)
- Testing
- Therapeutic Evaluative Conditioning, Neutral comparison condition
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Franciscan Hospital For Children, INC.
Self Harm, Suicidal Ideation
Leverage Noninvasive Transcutaneous Vagus Nerve Stimulation to Reduce Suicidal Behaviors in Vulnerable Adolescents
Suicidal thoughts, suicide attempts, and suicide are increasingly common in adolescence. Current face-to-face prevention approaches are of limited effectiveness, rely on extensive resources, and are at odds with adolescents'…
- Trial name
- NCT05602779
- Testing
- tVNS Program, Phone App Program, tVNS and Phone App Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Notre Dame
Adolescent Behavior
Brief Intervention for Suicide Risk Reduction in High Risk Adolescents
Adolescent suicide is the 2nd leading cause of death in this age group. There are no validated treatments to decrease the risk of adolescent suicidal behavior, and there are especially no interventions to target the highest risk…
- Trial name
- ASAP (NCT02272179)
- Testing
- As Safe As Possible, Brite, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Pittsburgh
Community Adolescents at Risk for Depression and Suicide
Application and Evaluation of Group Cognitive Intervention for Depressed Adolescents
Cognitive behavioral therapy (CBT) is effective and CBT with parental involvement has potential in preventing and treating adolescent depression.
- Trial name
- NCT00946413
- Testing
- CBT plus parent education, CBT alone
- Where
- Taiwan
- Volunteers
- 31 people
- Sponsor
- Taipei Medical University Hospital
Adolescent Behavior, Suicidal Ideation
Navigating Mental Health Treatment for Black Youth
This study looks to conduct a systematic adaptation of Suicidal Teens Accessing Treatment (STAT-ED) for Black youth presenting in the emergency department who have suicide risk.
- Trial name
- NCT05334381
- Testing
- Adapted STAT-ED, Standard Enhanced Treatment As Usual
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia