Clinical trials: Supportive Therapy
Paediatric, Invasive Procedure
Relational Music Therapy Procedural Support for Paediatric Patients and Families Facing Repeated Invasive Procedures
This study explores how personalised music therapy can support children and their parents during repeated medical procedures, such as blood tests or injections.
- Conditions
- Paediatric, Invasive Procedure, Relation, Family, Music Therapy
- Trial name
- NCT07680348
- Testing
- Music Therapy-Based Procedural Support (MTPS)
- Volunteers
- 20 people
- Sponsor
- Anglia Ruskin University
Edentulous Alveolar Ridge
Effectiveness of Removable Prosthesis Retained by 4 Implant-supported Locator-Attachments
1. Hypothesis/Specific aims The aim of the present study proposal is to validate an implant treatment concept in the edentulous upper maxilla using four implants-supported locators abutments to retain removable prosthesis.
- Trial name
- LOC (NCT02380404)
- Testing
- Implants-supported locators placement
- Where
- 2 sites in Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Liege
Attention Deficit Hyperactivity Disorder Combined
Evaluating the Feasibility of FAM-SOTC Intervention for Families of Adolescents With ADHD: Pilot Study
Attention-deficit/hyperactivity disorder (ADHD), is a highly genetic and complex neurological disorder, where disruptive behavior, emotional imbalance, and lack of attention can interrupt with normal development of adolescents…
- Trial name
- NCT04378517
- Testing
- psychosocial education in parents groups, psychosocial parents support, interviews with APN
- Where
- Iceland
- Volunteers
- 23 people
- Sponsor
- University of Iceland
Lymphoma
Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hodgkin's Disease
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells.
- Trial name
- NCT00004169
- Testing
- carboplatin, cyclophosphamide, etoposide
- Where
- United States
- Sponsor
- Northwestern University
Medication Adherence
Cell Phone Support to Promote Medication Adherence Among Adolescents and Young Adults With Chronic Illness
Background: Adolescents and young adults (AYAs) with chronic illnesses often struggle to develop illness self-management skills.
- Trial name
- NCT04241627
- Testing
- Cell Phone Support
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Children's Hospital Los Angeles
Children With Medical Complexity (CMC), Symptom Management
Nurse-led Integrated Home Service to Support Parents in Symptom Management for Children Requiring Respiratory Support
The aims of this study are to test the effectiveness of a nurse-led integrated home health service to enhance parental self-efficacy in symptom management for children requiring respiratory support, and alongside identify factors…
- Conditions
- Children With Medical Complexity (CMC), Symptom Management, Nurse-led Supportive Care, Self Efficacy
- Trial name
- NCT07652268
- Testing
- Nurse-led integrated home service
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 80 people
- Sponsor
- Dr Winsome Lam
Fulminant Myocarditis
Clinical Assessment of New Treatment Regimen for Adult Fulminant Myocarditis
This is a retrospective cohort study to assess the clinical outcome of patients with fulminant myocarditis using "Life-support Based Comprehensive Treatment Regimen" and conventional therapy.
- Trial name
- NCT03268642
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Tongji Hospital
Autism Spectrum Disorder
The Effect of Digital Storytelling and Sensory Integration on Children With Autism
Given the interest of children with Autism Spectrum Disorder (ASD) in using computers, this study examined the effect of Digital Storytelling (DST) activity on increasing activity participation and self-regulation.
- Trial name
- NCT06491875
- Testing
- Digital Storytelling (DST), Sensory Integration Therapy (SIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Biruni University
HIV/AIDS
Video-Intervention to Inspire Treatment Adherence for Life for Adolescents
This a two-arm randomized controlled trial whose objective is to explore the impact of VITAL Start for Adolescents (VS4A), a video-based antiretroviral treatment (ART) adherence intervention, on a range of implementation and…
- Trial name
- VS4A (NCT07064785)
- Testing
- Video-based ART adherence counseling, Standard of Care (SOC)
- Where
- 32 sites in Malawi
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Periodontal Diseases, Chronic Periodontitis
Photodynamic Therapy During Supportive Periodontal Therapy
27 subjects on SPT, each with at least two residual pockets ≥5mm, were recruited for this randomised, split-mouth controlled trial, providing a total of 72 sites.
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Attachment Loss
- Trial name
- NCT02666573
- Testing
- Fotosan 630, CMS Dental, Copenhagen, Denmark, Scaling and root planing
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Respiratory Syncytial Virus
Prospective Pilot Clinical Trial of Azithromycin Treatment In Respiratory Syncytial Virus (RSV)- Induced Respiratory Failure In Children
This randomized, double-blind, placebo-controlled phase 2 trial will be conducted at a single tertiary pediatric intensive care unit (PICU).
- Trial name
- NCT02707523
- Testing
- Azithromycin 10 mg, Azithromycin 20mg
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Alabama at Birmingham
Unspecified Childhood Solid Tumor, Protocol Specific
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Trial name
- NCT00003194
- Testing
- filgrastim, carboplatin, cyclophosphamide
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Seattle Children's Hospital
Childhood Obesity, Minority Health
Family, Responsibility, Education, Support, and Health for Latino Caregivers (FRESH-LC)
The objective of this proposed study is to collect initial efficacy data on a telehealth family-based behavioral program for Latino children with overweight or obesity, which also includes additional caregiver support (PBT-AC)…
- Trial name
- FRESH-LC (NCT05437406)
- Testing
- Parent-based treatment- All caregivers (PBT-AC), Health Education (HE)
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- University of California, San Diego
Temporomandibular Disorders (TMD)
Treatment Outcomes of Temporomandibular Disorders Using Stabilization Splint Supported by the T-scan System
This study aims to evaluate the treatment outcomes of temporomandibular disorders (TMD) using stabilization splints (SS) supported by the T-scan system at Hanoi Medical University Hospital.
- Trial name
- NCT06957665
- Testing
- T-scan Assisted Occlusal Adjustment with Stabilization Splint
- Where
- Vietnam
- Volunteers
- 36 people
- Sponsor
- Hanoi Medical University
Congestive Heart Failure
Study to Evaluate the Safety of Twice Daily Oral Carvedilol
The objective of this study is to evaluate the long-term safety of carvedilol in pediatric patients with chronic heart failure, who completed the Pediatric Carvedilol Study 321.
- Trial name
- NCT00129363
- Testing
- Carvedilol
- Where
- 17 sites in United States
- Volunteers
- 75 people
- Sponsor
- Shaddy, Robert, M.D.
Low Birthweight, Preterm Birth
Low Birthweight and Preterm Infant Feeding Trial and Supportive Care Package: Implementation Research
Low Birthweight and Preterm Infant Feeding Trial and Supportive Care Package (LIFT-UP) aims to improve feeding and growth outcomes among low birthweight (LBW; <2.5kg) or preterm (<37 weeks gestational age) infants admitted to…
- Trial name
- LIFT-UP (NCT06390943)
- Testing
- Facility-based feeding support package plus (FB-FSP+), Transition-to-home feeding support package plus (TTH-FSP+)
- Where
- 5 sites in India, Malawi and 1 more
- Volunteers
- 632 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Suicide Prevention
Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk
The investigators are modifying and testing the preliminary effectiveness and implementation of the combination of two psychosocial interventions, Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP) and the…
- Trial name
- NCT06941311
- Testing
- Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP), Youth-Nominated Support Team
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Bone Sarcoma, Osteosarcoma
Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients
This is a multicenter phase II study concerning patients with high-grade bone sarcoma (HGBS) without complete remission after standard treatment at diagnosis or at relapse.
- Trial name
- REGOMAIN (NCT04698785)
- Testing
- Treatment by regorafenib and best supportive care
- Where
- 16 sites in France
- Volunteers
- 36 people
- Sponsor
- Centre Leon Berard
Molar Hypomineralization, Dental Restoration Failure of Marginal Integrity
CAD-CAM or Adhesive Approaches for MIH Treatment
Aim: This randomized controlled clinical study aimed to compare direct composite resin restorations and Computer Aided Design-Computer Aided Manufacturing (CAD-CAM) supported inlay or onlay restorations in young permanent molar…
- Trial name
- NCT06456619
- Testing
- Tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Baskent University
Sexually Transmitted Diseases, Safe Sex
P3 (Prepared, Protected, emPowered)
P3 (Prepared, Protected, emPowered) is an interactive smartphone app for HIV-uninfected YMSM and YTW that utilizes social networking and game-based mechanics as well as a comprehensive understanding of what constitutes "best…
- Conditions
- Sexually Transmitted Diseases, Safe Sex, Adherence, Medication
- Trial name
- P3 (NCT03320512)
- Testing
- P3, P3+, Control
- Where
- 9 sites in United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill