Clinical trials: Surgical Outcome
Congenital Heart Disease in Children, Cardiac Surgical Procedures
Predictive Pre and Peroperative Factors for MODS-2 in Pediatric Cardiac Surgery
Pediatric cardiac surgery has a relatively high morbi-mortality. Despite great advances in surgical techniques, today the mortality rate is about 3% and morbidity is about 30-40%.
- Conditions
- Congenital Heart Disease in Children, Cardiac Surgical Procedures, Outcome Assessment, Organ Dysfunction Scores
- Trial name
- FPMODS2 (NCT05284500)
- Testing
- Pediatric cardiac surgery with cardiopulmonary bypass
- Where
- Belgium
- Volunteers
- 152 people
- Sponsor
- Brugmann University Hospital
Pediatric Cataract
Outcome of Capsular After Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
The aim of this study is to evaluate the outcome of capsular in children with cataract, and to explore potential preoperative structural clues for postoperative glaucoma.
- Trial name
- Capsular (NCT04357249)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wenzhou Medical University
Extranodal Extension
Tumor Deposits in Colorectal Cancers
Tumor deposits (TDs) are emerging as an adverse prognostic factor in colorectal cancers (CRCs), but they are quite ignored in the current staging system.
- Trial name
- TD (NCT05923450)
- Testing
- Colorectal Resection
- Volunteers
- 243 people
- Sponsor
- University of Campania Luigi Vanvitelli
Endometrial Cancer
Uterine Manipulator in Endometrial Cancer Surgery: Pro MUCEI Study
The uterine manipulator is a device commonly used in minimally invasive hysterectomy surgery for endometrial cancer. However, without substantial evidence to support its use, surgeons are required to make decisions about its use…
- Trial name
- proMUCEI (NCT05242276)
- Testing
- USE OF UTERINE MANIPULATOR DURING THE HYSTERECTOMY
- Where
- Spain
- Volunteers
- 1,200 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Capsular Contracture, Implant, Pediatric Cataract
Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
Lens capsular often changes after pediatric cataract surgery，causing complications such as anterior capsulerhexis shrinkage, visual axis opacification (VAO), zonular dehiscence and so on.
- Trial name
- capsular (NCT04803097)
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Yune Zhao
Von Hippel-Lindau Disease, Central Nervous System Hemangioblastoma
Pediatric Von Hippel-Lindau Disease: Natural History, Predictive Factors, and Long-Term Functional Outcomes of Central Nervous System Hemangioblastomas
Von Hippel-Lindau (VHL) disease is a rare hereditary cancer predisposition syndrome associated with the development of central nervous system hemangioblastomas from childhood.
- Trial name
- VHL-PED-CHB (NCT07705529)
- Where
- 3 sites in France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart; Surgery, Heart, Functional Disturbance as Result, Pediatric ALL
Oblique Versus Transverse Orientation Approach for Internal Jugular Venous Cannulation in Pediatrics
this study aimed to compare oblique versus transverse orientation approach in jugular venous cannulation in term of cannulation success in pediatric heart surgery patients
- Trial name
- NCT05656937
- Testing
- internal jugular venous cannulation
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Pediatric Congenital Heart Surgery
Predictive Value of the FORE-SIGHT™ Monitor for Hemodynamic Deterioration
The postoperative period after congenital heart surgery in children can be a very critical episode, where it is of utmost importance to closely monitor the circulation in these patients.
- Trial name
- NCT01706497
- Testing
- Cerebral tissue oxygen saturation monitoring, blinded
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- KU Leuven
Cataract, High Myopia
Evaluation of Cataract Surgery Outcome
The purpose of this study is to evaluate the visual outcome of the cataract surgery, including best uncorrected and corrected visual acuity, spherical equivalent, wavefront aberration and other measurements.
- Trial name
- NCT02182921
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Evidence Based Cataract Study Group
Periprosthetic Knee Infection
Outcome After Revisions of Infected Knee Arthroplasties
A prospective multicenter cohort study on all types of revision knee arthroplasty procedures performed due to infection.
- Trial name
- RIKA (NCT04427943)
- Testing
- revision surgery
- Where
- 8 sites in Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Aorta Dissection, Aorta Aneurysm
Hybrid Operation in Thoracic Aortic Dissection
The purpose of this study is to investigate the short to mid term efficacy and safety of different hybrid operations who had complex aortic lesions, such as ascending aortic/arch aneurysm, pseudo-aneurysm, Stanford Type A…
- Trial name
- NCT01500395
- Testing
- Hybrid operation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Pilonidal Sinus of Natal Cleft
Long-term Outcome After Pit-pick for Simple Pilonidal Sinus Disease
Single-center cohort study of long-term results after pit-pcik for pilonidal sinus disease.
- Trial name
- NCT05027607
- Testing
- Bascom's pit-pick
- Where
- Denmark
- Volunteers
- 158 people
- Sponsor
- Nordsjaellands Hospital
Acetabular Fracture
Function Outcome of Impaction Injuries in Acetabular Fractures
Is the anatomical reduction of osteochondral impaction in the acetabular fractures will improve the functional outcome? Despite the increasing amount of literature related to the management of anteromedial dome impactions and…
- Trial name
- NCT03152266
- Testing
- No intervention. Observational study
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Idiopathic Normal Pressure Hydrocephalus
Gait Pattern and Experienced Global Change After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus
Part 1 Patients with idiopathic Normal Pressure Hydrocephalus (iNPH) have variable disabilities regarding gait, balance, cognition and continence.
- Trial name
- NCT04795089
- Testing
- Shunt surgery
- Where
- Sweden
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Reflux, Gastroesophageal Reflux Disease (GERD)
RESULT (REflux Surgery in Lung Transplantation) Preliminary Study Protocol
The purpose of the prospective study is to collect information surrounding lung transplant in order to develop a randomized study to determine if prevention of gastroesophageal reflux disease (GERD) related aspiration (stomach…
- Trial name
- RESULT (NCT01406210)
- Where
- 4 sites in United States, Canada
- Volunteers
- 647 people
- Sponsor
- Duke University
Melanoma, Surgery
Trial of Surgical Excision Margins in Thick Primary Melanoma - 2
Objectives: The purpose of this study was to assess the long-term follow-up of the overall and melanoma-specific survival in the randomised, open-lable multicenter trial (NTC NCT01183936) comparing excision margin of 2 cm versus…
- Conditions
- Melanoma, Surgery, Treatment Outcome
- Trial name
- NCT03638492
- Testing
- 2-cm margin, 4-cm margin
- Volunteers
- 936 people
- Sponsor
- Peter Gillgren
Humeral Fractures, Fractures, Closed
Pain Management in Children Undergoing Supracondylar Humerus Fracture Repair
The purpose of this study is to determine if US-guided supraclavicular anesthetic blocks reduce postoperative pain, use of rescue medication, and improve functional outcomes in children who underwent surgery for supracondylar…
- Trial name
- NCT01812863
- Testing
- Supraclavicular nerve block
- Where
- United States
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Appendicitis Acute
Role of Duplex Doppler in Accurate Diagnosis of Appendicitis
To evaluate the role of duplex doppler in diagnosis of appendicitis compared to CT
- Trial name
- NCT04130074
- Testing
- duplex doppler ultra sound and CT
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- abdelRahman Ahmad abdAllah
Cardiac Toxicity, Sarcoma
Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy before surgery may shrink the tumor so that it can be removed during surgery.
- Trial name
- NCT00019864
- Testing
- filgrastim, cisplatin, dexrazoxane hydrochloride
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Cancer Institute (NCI)
Basilar Invagination, Prospective Study
A Prospective Study of Surgical Treatment Strategies for Goal B Type Basilar Invagination
The etiology of Goal B type basilar invagination (BI) is still not clear, and it may be related to platybasia and short slope. There is no unified standard surgical strategy for Goal B type BI, and different surgical strategies…
- Conditions
- Basilar Invagination, Prospective Study, Surgical Outcome
- Trial name
- NCT05849363
- Testing
- Posterior fossa decompression, Posterior Compression-Distraction-Reduction-Fixation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing