Clinical trials: Surgical Procedures, Operative
Aortic Valve Stenosis
Costs, Cognitive Abilities and Quality of Life After Transcatheter Aortic Valve Implantation and Surgical Aortic Valve Replacement
Multicenter, prospective, observational study in aortic stenosis (AS) patients undergoing transcatheter aortic valve implantation (TAVI) or high-risk patients undergoing aortic valve replacement (AVR).
- Trial name
- CCQ (NCT01852552)
- Testing
- transcatheter aortic valve implantation, Aortic Valve Replacement
- Where
- Italy
- Volunteers
- 518 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Intracranial Arteriovenous Malformations
Nationwide Treatment Survey of Intracranial Arteriovenous Malformation in China
This register study will collect the treatment information of the intracranial arteriovenous malformation patients in China. We aim to understand the current treatment situation of the disease in China.
- Trial name
- NTSIAVMC (NCT01803685)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Dr. Yong Cao
Surgery, Blood Loss, Surgical
Investigation of the Transfusion Practices in Surgical Patients in Turkey
The aim of this study is to describe the transfusion practices in patients undergoing major surgery in Turkey. The transfusion rates of red blood cells (RBC), fresh frozen plasma (FFP) and platelets; the transfusion predictors…
- Conditions
- Surgery, Blood Loss, Surgical, Blood Loss Anemia, Blood Transfusion
- Trial name
- CeKATU (NCT03468738)
- Testing
- Blood transfusion
- Where
- 61 sites in Turkey (Türkiye)
- Volunteers
- 6,481 people
- Sponsor
- Diskapi Teaching and Research Hospital
Early-Onset Scoliosis Deformity of Spine
Long-Term Follow-Up Of Surgical Management Of Early Onset Scoliosis Using Growing Rods
The aim of this work is to evaluate the long-term outcome of the graduates (those who completed the gradual lengthening procedures), to better understand the full scope and natural course of Growing Rods treatment for EOS and to…
- Trial name
- NCT04945343
- Testing
- Growing Rods
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Abdominal Aortic Aneurysm, Endovascular Procedures
Standardization of Physician-Modified Stent Grafts for Abdominal Aortic Aneurysms
This study explores the use of physician-modified stent grafts (PMSGs) for treating abdominal aortic aneurysms that are unsuitable for open surgery or standard endovascular grafts.
- Conditions
- Abdominal Aortic Aneurysm, Endovascular Procedures, Stents, Vascular Surgical Procedures
- Trial name
- RESTORE (NCT06585215)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Pelvic Organ Prolapse
Sacrospinous Ligament Fixation With Conventional Surgical Instruments in Chinese Apical Prolapse Female Patients
SSLF is typically a suture-based attachment of the vaginal apex to the sacrospinous ligament, either unilaterally or bilaterally.
- Trial name
- SSLF-CSI (NCT03782285)
- Testing
- sacrospinous Ligament Fixation
- Where
- 9 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
Preoperative Breast Magnetic Resonance Imaging for Patients Undergoing Mammoplasty
all female with operable breast cancer seeking health care at general surgery department Assiut university hospitals,and decision of therapeutic mammoplasty was taken depending on clinical examination, findings on mammography and…
- Trial name
- NCT03173469
- Testing
- magnetic resonance imaging of breast
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Anesthesia, Anesthesia, Local
Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children
Circumcision is one of the most commonly performed operations in the pediatric population and is a painful procedure. Circumcision is performed with two popular techniques, Plastibell and conventional dissection method (CDM).
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia, Pediatric ALL
- Trial name
- NCT05233683
- Testing
- Caudal block, Dorsal penile nerve block plus ring block, Circumcision with Plastibell
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Saud University
Colorectal Liver Metastases, Hepatocellular Carcinoma
Alternative Surgical Policy for Central Liver Tumors
Major hepatectomies have not negligible morbidity and mortality. However, when tumors invade middle hepatic vein (MHV) at caval confluence major surgery is usually recommended.
- Trial name
- NCT00600522
- Testing
- Ultrasound-guided hepatectomy
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Milan
Proximal Femoral Fracture
Proximal Femoral Fractures - Patient Population, Risk Factors, Surgical Performance and Outcome
Proximal femoral fractures are a typical pathology in elderly patients after a low-energy trauma. This study analyses preexisting risk factors for proximal femoral fractures as well as for failing to reach the previous functional…
- Trial name
- ProFi (NCT03768622)
- Testing
- surgery for pertrochanteric femoral fracture, surgery for femoral neck fracture
- Where
- Switzerland
- Volunteers
- 2,906 people
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Wound Breakdown
Fascial Dehiscence and Mortality
Nationwide cohort study on short- and long-term mortality of patients with and without postoperative fascial dehiscence. The cohort will be comprised of patient undergoing open colonic resection for colonic cancer registered in…
- Trial name
- NCT03008265
- Testing
- Postoperative fascial dehiscence
- Where
- Denmark
- Volunteers
- 9,000 people
- Sponsor
- Kristian Kiim Jensen
Systemic Sclerosis, Periodontitis
Periodontal Health Status in Patients with Systemic Sclerosis
The aim of the research will be to evaluate the effects of NSPT on clinical periodontal parameters, level of antioxidants in unstimulated saliva and the levels of biomarkers (VEGF, TGF-β, IL-17) in the GCF in SSc patients in…
- Trial name
- NCT05215431
- Testing
- periodontal examination's, determination of salivary antioxidants and cytokine levels (VEGF, TGF-β, Il-17) in gingival crevicular fluid, Non-surgical therapy of periodontitis, Activity of antioxidants in unstimulated saliva (GPX, SOD, UA), Total cytokine levels (VEGF, TGF-β, Il-17) in gingival crevicular fluid
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- University of Belgrade
Surgical Adhesions
Study of PXL01 Versus Placebo to Inhibit Adhesion Formation After Flexor Tendon Surgery
The objectives of the study are to assess efficacy, safety, and handling of PXL01 in patients with flexor tendon injury in zone I or II.
- Trial name
- PHSU02 (NCT01022242)
- Testing
- PXL01
- Where
- 15 sites in Denmark, Germany and 1 more
- Volunteers
- 138 people
- Sponsor
- Pergamum AB
Anesthesia and Analgesia, Pediatrics
Erector Spinae Plane Block for Peri-operative Pain Management in Pediatric Open Pyeloplasty Cases
Regional anesthesia decreases the need for intravenous analgesia in the peri-operative period. Erector spinae plane (ESP) and transversus abdominus plane (TAP) blocks are two common regional anesthesia techniques shown to be…
- Conditions
- Anesthesia and Analgesia, Pediatrics, Urologic Surgical Procedures
- Trial name
- ESPPOP (NCT03790566)
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Surgical Education
Validation of a Curriculum (STAC) for Technical Skill Acquisition in Minimally Invasive Surgery
This study describes the development and validation of a structured training and assessment curriculum (STAC) for a basic laparoscopic procedure.
- Trial name
- NCT01560494
- Testing
- STAC curriculum
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Staphylococcus Aureus, Surgical Wound Infection
Risk Factors for Staphylococcus Aureus Surgical Site Infections in Orthopedic and Trauma Surgery
The most commonly identified organism for Surgical Site Infection (SSI) in orthopedic surgery is Staphylococcus aureus but risk factors for mono microbial S.aureus SSI are not well-known.
- Conditions
- Staphylococcus Aureus, Surgical Wound Infection, Orthopedic Disorder, Traumatology
- Trial name
- ISO (NCT03040960)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Cerebral Palsy, Hip Dysplasia
Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT04074265
- Testing
- Ropivacaine injection, normal saline
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of California, Los Angeles
Intermittent Exotropia
Study of Non-surgical Treatment Versus Observation in Asian Children With Intermittent Exotropia
Non-surgical treatment (ie. patching or fusion exercises) of intermittent exotropia may help in increasing control of strabismus
- Trial name
- NCT01267500
- Testing
- Non surgical therapy
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Congenital Heart Disease in Children, Cardiac Surgical Procedures
Predictive Pre and Peroperative Factors for MODS-2 in Pediatric Cardiac Surgery
Pediatric cardiac surgery has a relatively high morbi-mortality. Despite great advances in surgical techniques, today the mortality rate is about 3% and morbidity is about 30-40%.
- Conditions
- Congenital Heart Disease in Children, Cardiac Surgical Procedures, Outcome Assessment, Organ Dysfunction Scores
- Trial name
- FPMODS2 (NCT05284500)
- Testing
- Pediatric cardiac surgery with cardiopulmonary bypass
- Where
- Belgium
- Volunteers
- 152 people
- Sponsor
- Brugmann University Hospital
Fracture, Radius
Management of Pediatric Distal Radius Fractures : Conservative Treatment Versus Surgical Reduction
To compare functional and radiological assessment between two groups of children with displaced distal radius fractures : those who will receive surgical reduction and those who will not.
- Trial name
- NCT06459557
- Testing
- cast, surgical reduction
- Volunteers
- 52 people
- Sponsor
- Assiut University
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