Clinical trials: Surgical Resection, open to volunteers
Mandibular Resection, Mandibular Reconstruction* / Methods
Patient-specific Reconstruction Plate for Segmental Mandibular Defects
The mandible's horseshoe-shaped anatomy makes the reconstruction of segmental defects a challenging procedure. Conventional reconstruction typically relies on alloplastic plates to bridge bony stumps; however, these require…
- Conditions
- Mandibular Resection, Mandibular Reconstruction* / Methods, Mandibular Reconstruction
- Trial name
- NCT07320924
- Testing
- Patient specific reconstruction plate
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Alexandria University
Colon Procedures, Bowel Resection
MIRA Registry Study: Post Market Surveillance Using the MIRA Surgical System
The purpose of the MIRA Surgical System Registry is to accumulate and evaluate real world evidence experience as part of post-market surveillance using the MIRA Surgical System.
- Trial name
- NCT06856707
- Testing
- Use of the MIRA Surgical System during surgery
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Virtual Incision Corporation
Melanoma
Review of the Literature and Serie of Patients Who Underwent Reconstruction After Wide Local Excision of Nail Apparatus for Melanoma
Melanomas of the nail bed are often diagnosed at the locally advanced stage. The standard treatment was amputation of the finger or toe, but it has now been established that enlarged excision of the nail plate is sufficient under…
- Trial name
- NCT06861023
- Testing
- Patients who have undergone extensive nail resection with reconstruction
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Periacetabular Tumor
A Randomized Controlled Study Evaluating Modified Cup Anteversion Placement in Prevention of Postoperative Dislocation in Patients Undergoing Acetabular Tumor Resection and Reconstruction
The purpose of this clinical study is to investigate whether patients who receive modified anteversion angle (( α-15°)±10°) of the acetabular cup have a lower risk of dislocation within one year after surgery, compared to…
- Trial name
- NCT05593146
- Testing
- modified anteversion angle placement(( α-15°)±10°), conventional anteversion angle placement ( α±10°)
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Rizarthrosis
Comparative Study Between the Use of Trapeziometacarpal Prostheses and the Usual Resection-tenosuspension Arthroplasty for the Treatment of Rhizarthrosis, Focusing on Changes in Pain (Measured With the VAS Scale) and Function (With the Quick-DASH).
It is a randomized, prospective, single-blind study of two treatment techniques for rhizarthrosis. The patients are divided into two groups: one in which a Maia trapeziometacarpal prosthesis is implanted, and the other in which…
- Trial name
- NCT07101887
- Testing
- Implantation of thumb prosthesis, Burton-Pellegrini technique
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Parc de Salut Mar
Rectal Cancer
SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak
The goal of this clinical trial is to learn whether using a reinforcing material called SIS (small intestinal submucosa) during bowel connection after rectal cancer surgery can help prevent anastomotic leakage-a serious…
- Trial name
- NCT07209787
- Testing
- SIS-reinforced anastomosis
- Where
- China
- Volunteers
- 966 people
- Sponsor
- Beijing Chao Yang Hospital
Liver Resection, Liver Tumours
Evaluation Of Liver Resection Using Harmonic Scalpel Versus Cavitron Ultrasonic Surgical Aspirator (CUSA).
Evaluation Of Liver Resection Using Harmonic Scalpel Versus Cavitron Ultrasonic Surgical Aspirator (CUSA) Introduction The mode of parenchymal transection in hepatic resection has been a topic of great debate for decades.
- Conditions
- Liver Resection, Liver Tumours, Liver Transplant Disorder, Trauma Abdomen
- Trial name
- NCT07142876
- Testing
- Liver resection Cavitron Ultrasonic Surgical Aspirator (CUSA), Liver resection with the harmonic scalpel
- Volunteers
- 50 people
- Sponsor
- Sohag University
Brain Arteriovenous Malformation
Registry of Multimodality Treatment for Brain Arteriovenous Malformation in Mainland China
This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program.
- Trial name
- MATCH (NCT04572568)
- Testing
- Multi-disciplinary assessment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Success of Operation
Comparative Study of Laparoscopic Combined Trans-vesical and Extravesical Versus Laparoscopic Extravesical Fistula Excision in Uterovesical Fistula Repair: A Retrospective Observational Study
The aim of this study is to compare between laparoscopic combined trans-vesical and extravesical versus laparoscopic extravesical fistula excision in uterovesical fistula repair.
- Trial name
- NCT06803160
- Testing
- Laparoscopic Extravesical Fistula Excision of Uterovesical Fistula, Laparoscopic Combined Fistula Excision of Uterovesical Fistula
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Melanoma (Skin Cancer), Skin Carcinoma
Biomechanical Characterization of Skin Properties Using Impact Based-Analysis Method (IBAM)
Skin palpation remains, alongside visual inspection, the main clinical tool used to detect cutaneous abnormalities. However, palpation is a subjective, operator-dependent examination with limited sensitivity.
- Trial name
- SkinTumor-IBAM (NCT07861022)
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire Henri Mondor, Assistance Publique Hôpitaux de Paris
Physician, Surgeon
Deformable Tissue Modelling and Augmented Reality Based Guidance for Head and Neck Tumor Re-Resection Task
Head and neck cancers have one of the highest recurrence rates among solid malignancies, and recurrence is strongly correlated with overall survival.
- Conditions
- Physician, Surgeon, Resident Doctor, Resident Surgeon
- Trial name
- SPeAR (NCT07686211)
- Testing
- Augmented Reality
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Pulmonary Function Assessment, Disease Free Survival
Pulmonary Watershed Topographic Map Navigation for Lung Nodule Resection
A method of ICG counterstaining localization under target artery occlusion without cutting，It's a new method of localization of small pulmonary nodules.
- Conditions
- Pulmonary Function Assessment, Disease Free Survival, NSCLC, Stage I
- Trial name
- NCT06404164
- Testing
- Wedge resection under watershed analysis method
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Colonic Polyp, Colonic Sessile Serrated Lesion
The CARMA Technique Study
Colonoscopic removal of polyps is an important and well-established tool in the prevention of colorectal cancers. However, high polyp recurrence rates after endoscopic resection, with resultant development of interval cancers…
- Trial name
- NCT05099432
- Testing
- CARMA technique
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- Princess Alexandra Hospital, Brisbane, Australia
Focal Epilepsy, Intraoperative Monitoring
High-density Flexible μECoG for Epilepsy Surgery - A Single-Arm ECT
What's the clinical value of high-density flexible microelectrocorticography (μECoG) for guiding the resection of epileptogenic zone (EZ) in epilepsy surgery?
- Trial name
- Epi-PRECISE (NCT07656857)
- Testing
- Using High-density Flexible microElectrocorticography for intraoperative monitoring
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Beijing Tiantan Hospital
Crohn Disease
Comparing Hand-sewn (END-TO-END or Kono-S) to Stapled Anastomosis in Ileocolic Resection for Crohn's Disease
The aim of this multicenter randomised controlled trial is to compare the handsewn (end-to-end and Kono-S) to the stapled side-to-side ileocolic anastomosis after ileocolic resection for Crohn's disease with respect to 6 months…
- Trial name
- END2END (NCT05578235)
- Testing
- stapled side-to-side anastomosis, Handsewn anastomosis
- Where
- Netherlands
- Volunteers
- 165 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Crohn's Disease (CD)
Unraveling the Blood Microbiome in Postoperative Recurrence of Crohn's Disease
Crohn's disease, a chronic inflammation of the gastro-intestinal tract, is a disease with a complex pathogenetic background. Hereditary factors, environmental factors and the gut flora play a varying role in its onset, however…
- Trial name
- IBDbloom (NCT06770140)
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Cholangiocarcinoma, Hilar
Volume-Restricted Resection for Perihilar Cholangiocarcinoma
The goal of this observational study is to learn about the safety and long-term outcomes of volume-restricted liver resection in patients with perihilar cholangiocarcinoma (pCCA) who have an insufficient future liver remnant…
- Trial name
- NCT07149558
- Volunteers
- 300 people
- Sponsor
- Yongjun Chen
Breast Cancer Invasive
Intra-operative Detection of Positive Margins and Lymph Nodes in Breast Surgery
In this project, the investigators will develop novel optical coherence tomography (OCT)-Raman spectroscopy and autofluorescence (AF)-Raman spectroscopy systems based on a selective sampling approach optimised for high-resolution…
- Trial name
- NCT06977698
- Testing
- OCT-Raman, AF-Raman
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Benign Prostatic Hyperplasia, Post-Op Complication
Artery Embolization vs Operation of Benign Prostate Hyperplasia
Aim of the study is to compare prostate artery embolization (PAE) to the established surgical treatment for patient acceptance, morbidity, complications, and the functional outcomes.
- Conditions
- Benign Prostatic Hyperplasia, Post-Op Complication, Embolization Therapeutic, Transurethral Resection of Prostate Syndrome
- Trial name
- NORTAPE (NCT04084938)
- Testing
- Prostate operation or prostate artery embolization
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Adult Pleomorphic Rhabdomyosarcoma, AJCC Grade 2 Sarcoma
Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue Sarcoma
This phase III trial compares chest computed tomography (CT) to chest x-ray (CXR) for lung surveillance after curative-intent resection of high-risk truncal-extremity soft tissue sarcoma.
- Conditions
- Adult Pleomorphic Rhabdomyosarcoma, AJCC Grade 2 Sarcoma, AJCC Grade 3 Sarcoma, Alveolar Soft Part Sarcoma
- Trial name
- NCT06526897
- Testing
- Biopsy, Chest Computed Tomography, Chest Radiography
- Volunteers
- 1,582 people
- Sponsor
- ECOG-ACRIN Cancer Research Group