Clinical trials: Symptom Tracking
Rett Syndrome
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials.
- Trial name
- VIBRANT (NCT06338267)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Rett Syndrome Research Trust
Autism Disorder, Language Development Disorders
Rural Autistic Individuals - Supporting Expression
This research study investigates how hand gestures can support language comprehension and communication skills of hearing speaking, non-speaking, and/or minimally verbal individuals with Autism Spectrum Disorders (ASD), who are…
- Conditions
- Autism Disorder, Language Development Disorders, ADHD, Typical Development
- Trial name
- RAISE (NCT07054866)
- Testing
- Speech-Gesture combinations
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montana State University
Premature Baby, Pulmonary Hypertension of Newborn
Measuring Heart Health in Both Term, Preterm and Unwell Newborn Babies With an Advanced Ultrasound Method: Speckle Tracking Echocardiography
This study aims to improve how neonatologists check the heart function of newborn babies, especially those who are sick. While standard heart ultrasound scans are useful, a more advanced and sensitive technique called 2D speckle…
- Conditions
- Premature Baby, Pulmonary Hypertension of Newborn, Hypoxic Ischaemic Encephalopathy (HIE), Congenital Diaphragmatic Hernia
- Trial name
- NCT07364682
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Diastolic Dysfunction, Neonatal Encephalopathy
Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography
The goal of this single-centre longitudinal observational study is to create reference values for diastolic function parameters in neonates born at 35 weeks' gestation or above, and to assess the influence of pre-defined…
- Conditions
- Diastolic Dysfunction, Neonatal Encephalopathy, Small for Gestational Age at Delivery, Transient Tachypnea of the Newborn
- Trial name
- DiFuSE (NCT06200519)
- Where
- Ireland
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University College Cork
Childhood Obesity
Whole-exome Sequencing in Childhood Obesity
Obesity is a complex multifactorial disease where genetics play an important role in predisposing children to early onset obesity.
- Trial name
- NCT02418377
- Where
- 2 sites in Singapore
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Communication Disabilities
Eye-tracking Technology for Severe Communication Disability
The aim of this project is to develop an Augmentative and Alternative Communication intervention through the use of Eye tracker system.
- Trial name
- NCT05808478
- Testing
- AAC + Eye Tracking, AAC
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
B-cell Lymphoma, Chronic Lymphocytic Leukemia
Long-Term Follow-Up of AvenCell Sponsored CAR-T Cell Clinical Trials
The goal of this clinical study is to learn more about the long-term safety, effectiveness and prolonged action of patients who participated in an AvenCell-sponsored clinical trial and received treatment with AvenCell's UniCAR or…
- Conditions
- B-cell Lymphoma, Chronic Lymphocytic Leukemia, Hematologic Malignancy, AML (Acute Myelogenous Leukemia)
- Trial name
- PERSIST (NCT07474051)
- Testing
- UniCAR02-T (IMP) With Targeting Module TM123, UniCAR02-T-pPSMA, Allo-RevCAR01- T with Targeting Module R-TM123
- Where
- 5 sites in Germany
- Volunteers
- 178 people
- Sponsor
- AvenCell Therapeutics, Inc.
Language Development, Language Development Disorders
Cortical Tracking of Speech in the First Year of Life
The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as…
- Conditions
- Language Development, Language Development Disorders, Infant Development, Infant Developmental Assessment
- Trial name
- NCT07531706
- Testing
- Electrophysiological recording, Behavioral Assessment
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Diabetes Mellitus, Obesity
Early Tracking of Childhood Health Determinants (ETCHED) Study
Background: Children s weight has increased sharply in recent years. This may put them at higher risk for health problems. High blood glucose in a pregnant mother and too much weight gain during pregnancy also may have long-term…
- Conditions
- Diabetes Mellitus, Obesity, Fatty Liver
- Trial name
- NCT03481829
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Autism
Validation of Indiana's Early Evaluation Hub System
The investigators' objective is to test an innovative method of autism diagnosis that integrates clinical evaluation and assessment of biobehavioral markers in a large high-risk community-referral sample of children in the…
- Trial name
- EAER21 (NCT06586788)
- Testing
- Eyelink Portable Duo, Integrated PCP Diagnosis and Eye-tracking Biomarker
- Where
- 7 sites in United States
- Volunteers
- 154 people
- Sponsor
- Indiana University
Growth, Overweight
Diet and Well-being of Young Danish Children Born by Obese Mothers
The overall aim is to provide a detailed description of growth, development and risk factors for later disease, especially obesity and metabolic disease in infants born by obese mothers and to compare them with a group of infants…
- Conditions
- Growth, Overweight, Metabolic Syndrome, Obesity
- Trial name
- SKOT II (NCT02377973)
- Where
- Denmark
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Concussion, Brain
Objective Concussion Assessment Using MRI and Metabolomics
Mild traumatic brain injury (mTBI), also referred to as concussions, affect millions of people around the world and can cause harmful long term effects.
- Trial name
- NCT05993351
- Testing
- Magnetic resonance imaging (MRI), Urine and saliva samples, Questionnaires
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Amblyopia
Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision Screening
Amblyopia, characterized by reduced visual acuity, develops in childhood due to insufficient sensory stimulation of the affected eye.
- Trial name
- FALSSE (NCT07112560)
- Testing
- Standard screening procedure for amblyopia, New amblyopia screening method using a virtual reality headset.
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Malignant Mesothelioma, Metastatic Cancer
Mesothelin and Osteopontin as Diagnostic Markers in Patients With Mesothelioma or Atypical Mesothelial Hyperplasia
RATIONALE: Studying levels of mesothelin and osteopontin in samples of blood from patients with mesothelioma or atypical mesothelial hyperplasia may help doctors identify biomarkers related to cancer.
- Trial name
- NCT00899613
- Testing
- laboratory biomarker analysis, study of high risk factors
- Where
- France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Caen
Morbid Obesity
Clinical Staging Tools for the Impacts of Obesity on Individuals
This study will assess various published staging tools to assess the health impacts of obesity on individuals. The aim is to identify benefits and drawbacks, and thus help Obesity Centres and GPs better assess obese individuals…
- Trial name
- COST (NCT01112228)
- Testing
- Bariatric surgery
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- Imperial College London
Atrial Fibrillation New Onset, New Onset Atrial Fibrillation
Tracking Atrial Fibrillation After Intensive Care Admission
Atrial fibrillation (AF) is a heart problem that causes an irregular heartbeat. It can cause the heart to beat more rapidly and reduce the heart's ability to pump blood around the body efficiently, causing heart failure.
- Conditions
- Atrial Fibrillation New Onset, New Onset Atrial Fibrillation, Atrial Fibrillation
- Trial name
- TrAFFIC (NCT05229211)
- Testing
- Cardiac monitoring
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Oxford
Chronic Renal Disease, Chronic Renal Insufficiency
2D-speckle Tracking in Pediatric Renal Chronic Disease
The SPECKLE- KIDNEY-PED is a multicentre observational controlled trial aiming to evaluate the 2D-Speckle tracking in a population of 85 patients aged from 6 to 17 years old with a chronic renal disease and to compare the results…
- Conditions
- Chronic Renal Disease, Chronic Renal Insufficiency, Congenital Heart Disease
- Trial name
- SPECKLEKIDNEY (NCT04897672)
- Testing
- Observational study
- Where
- France
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Premature Ventricular Complexes, Ventricular Arrhythmias
Impact of Catheter Ablation of Frequent Premature Ventricular Complexes in Treating Subtle Left Cardiomyopathy
Throughout the past decade, there were no straightforward recommendations regarding the management of asymptomatic high-burden Premature ventricular complexes (PVCs) in structurally normal heart extending from the European…
- Trial name
- NCT06864429
- Testing
- Radiofrequency catheter ablation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Epilepsy, Generalized, Absence Epilepsy
Detecting Absence Seizures Using Eye Tracking
The goal of this study is to develop a comfortable system that uses a wearable eye-tracker similar to eyeglasses to assist people with epilepsy in counting and measuring the severity of seizures.
- Conditions
- Epilepsy, Generalized, Absence Epilepsy, Absence Seizures, Seizures
- Trial name
- NCT04439656
- Testing
- Eye movement analysis
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Rachel Kuperman
Major Depressive Disorder, Bipolar Disorder
An Eye Tracking Study of Affective Disorder Patients With Suicide Risk
This research tries to investigate the validity and reliability of eye-tracking technologies by using different paradigms (eg. free-view, pro-saccade and anti-saccade) which served as a novel way of evaluating suicide risk among…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Suicide
- Trial name
- NCT03711045
- Testing
- eye-tracking
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University