Clinical trials: Symptom Tracking
Rett Syndrome
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials.
- Trial name
- VIBRANT (NCT06338267)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Rett Syndrome Research Trust
Analgesia
Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve (PECS) Block
In 2012 Blanco et al. [1] described the ultrasound technique for Pectoral nerve (PECS) block as a new, less invasive regional analgesic technique for breast surgeries.
- Trial name
- NCT06636578
- Testing
- dexmedetomidine, ropivacaine, fentanyl
- Where
- 2 sites in Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Non-small Cell Lung Cancer, Radiation Toxicity
Radiation-induced Cardiac Toxicity After Non-small Cell Lung Cancer Radiotherapy
Despite the growing interest in investigating how the radiotherapy (RT) dose to anatomical substructures of the heart links to survival, the heart substructures at risk remain poorly defined.
- Conditions
- Non-small Cell Lung Cancer, Radiation Toxicity, Cardiac Toxicity
- Trial name
- NCT04867564
- Testing
- Echocardiography
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Military Institute od Medicine National Research Institute
Cognitive Deficits, Depression
Attentional Bias Modification Through Eye-tracker Methodology (ABMET)
Cognitive biases are a hallmark of depression but there is scarce research on whether these biases can be directly modified by using specific cognitive training techniques.
- Conditions
- Cognitive Deficits, Depression, Alteration of Cognitive Function
- Trial name
- ABMET (NCT02847793)
- Testing
- Gaze training
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad Complutense de Madrid
Weight Loss
Weight Tracking and Weight Loss Outcomes: Establishing the Standard of Care
To achieve the long term goal of strengthening behavioral weight loss programs, the purpose of this project is to test an enhanced, daily weight tracking instruction against the current standard of care (weekly weight tracking)…
- Trial name
- Tracking (NCT01646086)
- Testing
- 12 month behavioral weight loss intervention
- Where
- United States
- Volunteers
- 339 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Traumatic Brain Injury (TBI) Patients, Severe Traumatic Brain Injury
SeeMe: Using Automated Facial Tracking to Detect Voluntary Behavior in Brain Injury
Objective: This prospective interventional study introduces "SeeMe," an automated, high-resolution computer vision platform designed to objectively quantify microscopic, auditory command-evoked movements in patients with…
- Trial name
- NCT07560631
- Testing
- SeeMe Multimodal Auditory Command Protocol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Subjective Memory Complaints, Anxiety
Eye-tracking Training for Older Adults
The goal of this clinical trial is to learn if a computerized eye-tracking training program can improve mental health and thinking skills in older adults.
- Trial name
- NCT07690709
- Testing
- Eye-Tracking Training
- Where
- 2 sites in Hong Kong
- Volunteers
- 78 people
- Sponsor
- Chinese University of Hong Kong
Breast Neoplasm Female, Quality of Life
Wearable Enhanced Fitness Tracking for Metastatic Breast Cancer Patients Using Endocrine Treatment and Palbociclib
Combining a fitness tracker technology with real-time patient-reported outcome monitoring associated with interventions through a health care app is a novel strategy to evaluate metastatic breast cancer patients using Palbociclib…
- Trial name
- WEFITTER (NCT05277935)
- Testing
- Use of the WeCancer app combined with the smartwatch.
- Where
- 4 sites in Brazil
- Volunteers
- 68 people
- Sponsor
- Beneficência Portuguesa de São Paulo
Sepsis, Septic Shock
Global Longitudinal Strain Assessment in Cardiogenic Shock During Sepsis
Cardiogenic shock is a condition of low cardiac output that represents the end of a progressive deterioration of cardiac function.
- Conditions
- Sepsis, Septic Shock, Cardiogenic Shock
- Trial name
- GLASSES-1 (NCT04141410)
- Testing
- Levosimendan, Echocardiography
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Azienda USL Toscana Centro
Heart Failure
Vivio At-Home Study
The purpose of the study is to examine the Vivio System's ability to track heart failure status in subjects, and compare the Vivio System's measurements to CardioMEMS measurements.
- Trial name
- NCT07730268
- Testing
- Vivio measurement
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- Ventric Health, LLC
Adverse Events in COVID-19 Vaccination
App-based Symptom Tracking After Corona Vaccination (CoCoV)
The study investigates the side effects of different COVID-19 vaccines.
- Trial name
- NCT04686409
- Testing
- COVID-19 vaccines
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Stuttering, Adult
Information Processing Biases in Adults Who Stutter
The goal of this clinical trial is to examine whether stuttering is associated with a tendency to attend more quickly or for longer durations to threat-related information in the environment (threat-related attention bias).
- Trial name
- NCT06422442
- Testing
- Threat-related stimulus exposure
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Lung Cancer
Combination of the Hedgehog Inhibitor, LDE225, With Etoposide and Cisplatin in the First-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC)
The purpose of this study is to test the safety of study drug LDE225 at different dose levels. The investigators will be testing three different dose levels and the dose will depend on when the patients enters the study and which…
- Trial name
- NCT01579929
- Testing
- LDE225, Etoposide and Cisplatin
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Autism Disorder, Language Development Disorders
Rural Autistic Individuals - Supporting Expression
This research study investigates how hand gestures can support language comprehension and communication skills of hearing speaking, non-speaking, and/or minimally verbal individuals with Autism Spectrum Disorders (ASD), who are…
- Conditions
- Autism Disorder, Language Development Disorders, ADHD, Typical Development
- Trial name
- RAISE (NCT07054866)
- Testing
- Speech-Gesture combinations
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montana State University
Cognitive Decline
TRIAD - Tracking Risk in Integrated Alzheimer's Diagnostics.
The study is based on the hypothesis that the integration of biological, psychological, and social factors, according to the biopsychosocial paradigm, allows for more accurate identification of the different stages of the…
- Trial name
- TRIAD (NCT07399418)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Premature Baby, Pulmonary Hypertension of Newborn
Measuring Heart Health in Both Term, Preterm and Unwell Newborn Babies With an Advanced Ultrasound Method: Speckle Tracking Echocardiography
This study aims to improve how neonatologists check the heart function of newborn babies, especially those who are sick. While standard heart ultrasound scans are useful, a more advanced and sensitive technique called 2D speckle…
- Conditions
- Premature Baby, Pulmonary Hypertension of Newborn, Hypoxic Ischaemic Encephalopathy (HIE), Congenital Diaphragmatic Hernia
- Trial name
- NCT07364682
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Axial Spondyloarthritis, Axial Spondyloarthritis (AxSpA)
A LONGITUDINAL OBSERVATIONAL STUDY to EVALUATE the EFFICACY of MOVEMENT and IMPLEMENT CONCRETE MOVEMENT RECOMMENDATIONS with the HELP of MOBILITY TRACKING with SMARTWATCHES in SUBJECTS with AXIAL SPONDYLOARTHRITIS
Axial spondyloarthritis (axSpa) is a chronic inflammatoric autoimmune disease of the back with a prevalence around 1,4% (1) . In patients decreased function and decreased quality of life as well as chronic pain are strong burdens…
- Conditions
- Axial Spondyloarthritis, Axial Spondyloarthritis (AxSpA), Axial Spondylarthritis (r-axSpA), Axial Spondyloarthopathy
- Trial name
- SPARTAKUS (NCT06807853)
- Testing
- Smartwatch
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Bonn
Tremor
Electromagnetic Tracking to Measure Tremor
Deep Brain Stimulation (DBS) is an effective treatment option for individuals with debilitating tremors that do not respond to medical therapy.
- Trial name
- NCT02641366
- Testing
- Electromagnetic tracking, Tremor kinetics after DBS, Tremor kinetics before and after DBS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Coronavirus, Depression
Social Media and COVID-19
In this protocol, we seek to examine the role of popular messaging platform WhatsApp in information spread during a crisis. As there have been few global crises in the last decade (coinciding with the rise of social media), the…
- Conditions
- Coronavirus, Depression, Anxiety, Stress
- Trial name
- NCT04367363
- Testing
- Social media & news consumption
- Where
- Singapore
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Jean Liu
Acute Respiratory Failure Requiring Mechanical Ventilation
Eye-Control Trial: Wearable Eye-Tracking Device as Means of Communication
The purpose of this study is to evaluate the feasibility of use of a wearable communication device for critically ill patients who are admitted to the intensive care unit (ICU) and mechanically ventilated.
- Trial name
- NCT04582149
- Testing
- EyeControl Eye-tracking Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University