Clinical trials: System Validation
Breakthrough Pain, Palliative Medicine
Paediatric Breakthrough Pain Assessment
Many children and young people with life-limiting and life-threatening illnesses get sudden bursts of pain called breakthrough pain. At the moment, there aren't any good ways to measure this pain in children and young people.
- Conditions
- Breakthrough Pain, Palliative Medicine, Oncology Pain, Pediatric ALL
- Trial name
- BEACON (NCT06790719)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Lung Cancer, Breast Cancer
Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis
The aim of this observational study is to comprehensively analyze the metabolites in plasma samples from multi-cancer patients using advanced mass spectrometry detection technology, in conjunction with metabolomics approaches.
- Conditions
- Lung Cancer, Breast Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT06363123
- Where
- 4 sites in China
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Transition-age Youth, Developmental Disabilities
Evaluation of Project TEAM (Teens Making Environmental and Activity Modifications)
The purpose of this study is to determine the extent to which Project TEAM (Teens making Environment and Activity Modifications) is an effective, socially valid, and feasible intervention that prepares youth with developmental…
- Conditions
- Transition-age Youth, Developmental Disabilities, Cerebral Palsy, Autism
- Trial name
- ProjectTEAM (NCT02714868)
- Testing
- Project TEAM, Matched Comparison
- Volunteers
- 82 people
- Sponsor
- Boston University Charles River Campus
Chronic Headache
The Turkish Fear of Pain Questionnaire
Children's chronic pain is a significant condition that affects roughly 25% of children, with approximately 3% of them requiring intense pain therapy.
- Trial name
- NCT05414513
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Neuromuscular Diseases
Feasibility, Validation and Application of Digital Tools for the Follow-up of Neuromuscular Patient Mobility in Daily Living
The low prevalence of rare diseases hinders the design of clinical studies with sufficient statistical power to demonstrate the efficacy of new drugs.
- Trial name
- DT4RD (NCT05798325)
- Testing
- 2MWT, MFM32, MyoGrip
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 40 people
- Sponsor
- Institut de Myologie, France
Respiratory Diseases, Chronic and Acute Respiratory Failure
Validation of a Simulated Clinical Evaluation of Ventilators
The purpose of this study is to evaluate the ability of a device reproducing patients' respiratory characteristics to select in-VITRO the most appropriate ventilator for a given pathology.
- Trial name
- SIMULVENTI (NCT01113255)
- Testing
- bench-evaluation, of three ventilators
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Syncope
Improving Management of Emergency Department Patients With Undifferentiated Syncope: Prospective Validation of the Canadian Syncope Risk Score
Among Kaiser Permanente Northern California (KPNC) health plan members, age ≥16 years, with recent syncope and presyncope undergoing emergency department (ED) management with a point-of-care clinical decision support (CDS) tool…
- Trial name
- NCT05538143
- Testing
- Comprehensive ED syncope/presyncope management tool
- Where
- 5 sites in United States
- Volunteers
- 4,000 people
- Sponsor
- Kaiser Permanente
Asthma, Allergic Rhinitis
RAPP-children, Rhinitis & Asthma in Patient Perspective: Development and Validation of a Questionnaire for Quality of Life Evaluation in Children With Asthma and Allergic Rhinitis
This observational study aims at developing and validating a simple questionnaire to be routinely applied in the clinical practice, for the evaluation of the quality of life in children with concomitant asthma and allergic…
- Trial name
- RAPP (NCT03276416)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Neuroblastic Tumors
Construction and Validation of an Intelligent Ultrasound Diagnostic System for the Spectrum of Neuroblastoma in Children
The goal of this observational study is to build an intelligent ultrasound diagnostic system that integrates pathological typing, risk stratification and prognosis assessment. The main question it aims to answer is: 1.
- Trial name
- NCT07549425
- Where
- 6 sites in China
- Volunteers
- 300 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Cerebral Palsy, Visual Impairment
Turkish Validity and Reliability of the Visual Function Classification System (VFCS)
Cerebral Palsy (CP) is the most common childhood disorder that occurs with a lesion in the developing infant brain, seen in 2-3/1000 live births.
- Conditions
- Cerebral Palsy, Visual Impairment, Visual Disorder, Cerebral Visual Impairment
- Trial name
- NCT05102955
- Testing
- Observational questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Epilepsy
Attention-Deficit Hyperactivity Disorder (ADHD) Rating Scale and Epilepsy
The cognitive and psychiatric comorbidities are crucial endpoints in epileptic patients. Among these comorbidities, the Attention-Deficit Hyperactivity Disorder (ADHD) accounts for one of the most important in terms of frequency…
- Trial name
- NCT01482026
- Testing
- ADHD Rating Scale-IV
- Where
- 15 sites in France
- Volunteers
- 173 people
- Sponsor
- Hospices Civils de Lyon
Chronic Urticaria
Validation of an Urticaria Control Test
The aim of this study is to validate a previously developed patient reported outcome instrument (in project UCT-D) to assess disease control in chronic urticaria patients (Urticaria Control Test - UCT) of age 12 and older.
- Trial name
- UCT-V (NCT01614834)
- Where
- 2 sites in Germany
- Volunteers
- 120 people
- Sponsor
- Charite University, Berlin, Germany
Rett Syndrome
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials.
- Trial name
- VIBRANT (NCT06338267)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Rett Syndrome Research Trust
Allergy, Immunoglobulin E-Mediated Allergic Disorder
Kenota 1 CWS Method Comparison Validation Study
The goal of this Method Comparison Study is to compare total IgE results obtained from at least 360 subjects aged less than 80 years old using four different testing arms comprising three types of samples and two testing methods.
- Trial name
- NCT05702671
- Testing
- Total Immunoglobulin E, Obtained From Fingerstick Sample
- Where
- 3 sites in United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Kenota Inc.
Cystic Fibrosis
Human Factors Study to Validate the User Interface of TOBI Podhaler Using Placebo Capsules
The purpose of this study is to validate the user interface of TOBI Podhaler by establishing that the product can support safe and effective use for the intended users
- Trial name
- NCT03502070
- Testing
- Tobi Podhaler
- Where
- 9 sites in United States
- Volunteers
- 47 people
- Sponsor
- Mylan Inc.
Food Allergy
Quality of Life in Food Allergy: Validation of Three Mini-questionnaires
The evaluation of the quality of life (QOL) in food allergy (AA) is difficult due to the lack of a currently validated questionnaire.
- Trial name
- EVAALIM (NCT06112873)
- Testing
- Quality of Life Questionnaire
- Volunteers
- 600 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Autoimmune Pancreatitis, Pancreatic Cancer
To Differentiate Focal Autoimmune Pancreatitis From Pancreatic Cancer by Endoscopic Ultrasound
Autoimmune pancreatitis (AIP) is a special type of chronic pancreatitis mediated by autoimmunity. The classic manifestation of AIP is diffuse pancreatic enlargement, some of which are characterized by focal enlargement.
- Trial name
- NCT04834505
- Testing
- Diagnostic imaging modalities for validation sample, EUS for derivation sample
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Peking Union Medical College Hospital
Dementia, Memory Impairment
Cultural and Linguistic Adaptation and Normative Study of the Turkish Version of the Free and Cued Selective Reminding Test: 16-Word Version (FCSRT-T)
An Adaptation Study of Free and Cued Selective Reminding Test in Turkish
- Trial name
- FCSRT-T (NCT05756231)
- Testing
- SIHT-16
- Where
- Turkey (Türkiye)
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Cerebral Palsy, Spastic, Cerebral Palsy
The Validity and Reliability of the Turkish Version of TASC and the Relationship Between SMC and Motor Functions
Selective motor control (SMC) impairment in children with cerebral palsy (CP) includes movement patterns dominated by flexor or extensor synergy affecting functional movements.
- Conditions
- Cerebral Palsy, Spastic, Cerebral Palsy, Cerebral Palsy Spastic Diplegia, Cerebral Palsy Quadriplegic
- Trial name
- NCT04231227
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs)
Validation of the EQ-5D-Y-3L and EQ-5D-Y-5L for Paediatric Patients in China
The goal of this observational study is to validate the EQ-5D-Y-3L and EQ-5D-Y-5L in measuring health-related quality of life (HRQoL) for paediatric patients with different health conditions in China.
- Conditions
- Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs), Pneumonia Childhood, Neuroblastoma (NB)
- Trial name
- NCT06873672
- Where
- China
- Volunteers
- 360 people
- Sponsor
- RenJi Hospital