Clinical trials: Test
Clinical Trials
Sample Size for Multivariate Time-to-event Data
Most of randomized clinical trials (RCT) using time-to-event criteria as the primary endpoint are designed, powered and analyzed based on an hypothetical hazard ratio (HR) corresponding to the targeted effect size between…
- Trial name
- NCT03964402
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Institut Bergonié
Cystic Fibrosis (CF)
Sweat Testing in Infants: Comparing Sweat Collection on Upper Vs Lower Limbs
The goal of this study is to compare the rate of Quantity Not Sufficient (QNS) during sweat collection in infants under 6 months of age, using the Macroduct Advanced device for sweat testing.
- Trial name
- NCT06902363
- Testing
- Macroduct Advanced
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
COPD
Dyspnea Threshold During 6 Minutes Walk Test
In view of the multiple limitations and restrictions relative to CPET (technical, time, physical…), determination of individualized training threshold from this evaluation is today not possible for a lot of patients.
- Trial name
- SD6 (NCT02082925)
- Testing
- Patient has to get up his hand when he defined his dyspnea threshold during 6MWT
- Where
- France
- Volunteers
- 82 people
- Sponsor
- 5 Santé
Type1 Diabetes Mellitus
Comparison of Motor and Sensory Functions of the Hand in Children With Type 1 Diabetes Mellitus and Their Healthy Peers
Type 1 Diabetes Mellitus (T1DM) is a condition where the body cannot produce a hormone called insulin. Although it is commonly seen in children and young people, it can occur at any age.
- Trial name
- NCT06206317
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Erdal AYDIN
Bladder Cancer, Urocystitis
A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose bladder cancer by comparing with clinical standard method…
- Conditions
- Bladder Cancer, Urocystitis, Urinary Bladder Stone, Urothelial Carcinoma
- Trial name
- NCT05337189
- Testing
- Urine DNA methylation analysis, medical imaging and/or cystoscopy and/or pathological examination
- Where
- China
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Trisomy 13, Trisomy 18
Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial
This prospective blinded study will assess the diagnostic capability of an informatics enhanced SNP based technology (Parental Support) to identify pregnant women who are carrying a fetus with an aneuploidy from fee floating DNA…
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Aneuploidy
- Trial name
- PreNATUS (NCT01545674)
- Testing
- Blood Draw
- Where
- 29 sites in United States, Canada and 4 more
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Rhinitis, Allergic, Perennial
A Clinical Study To Test A Nasal Spray (Fluticasone Furoate Nasal Spray) For The Treatment Of Perennial (Year-round) Allergic Rhinitis
The purpose of this study is to compare the effects (effectiveness and safety) of an intranasal corticosteroid (fluticasone furoate nasal spray [FFNS]), with a placebo nasal spray for the treatment of perennial (year-round)…
- Trial name
- NCT00609674
- Testing
- Fluticasone furoate nasal spray
- Where
- 37 sites in United States, Canada and 5 more
- Volunteers
- 315 people
- Sponsor
- GlaxoSmithKline
Infertility, Genetic Disease
Follow-up With Preimplantation Genetic Testing Patients
The main purpose of this study is to perform longitudinal evaluations of clinical outcomes and personal perspectives following utilization of preimplantation genetic testing (PGT).
- Conditions
- Infertility, Genetic Disease, IVF
- Trial name
- NCT04477863
- Testing
- Follow-up Interview
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Genomic Prediction Inc.
Oesophageal Atresia, Dumping Syndrome
Dumping Syndrome After Operation of Esophageal Atresia Type III
The purpose of this study is to evaluate the prevalence at 3.5 months of age of dumping syndrome in children operated at birth for oesophageal atresia type III et IV.
- Trial name
- DUMPING (NCT02525705)
- Testing
- Oral Glucose
- Where
- 10 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Lille
Skin Hyperpigmentation, Dry Skin; Eczema
Efficacy and Safety Assessment of Niacinamide Cosmetic Preparation: a Randomized Controlled Trial
Niacinamide in lower concentrations has been recognized as a cosmetic ingredient with hydrating properties. Therefore, aim was to test the efficacy and safety of niacinamide cosmetic preparation in A Randomized, Controlled Trial.
- Trial name
- NCT06189105
- Testing
- miss alice face it you love me serum, No treatment (usual skincare rutine)
- Where
- Croatia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Back Pain, Sciatica
Predictive Value of the Five-repetition Sit-to-stand Test After Lumbar Spine surgerySTS-3 Study.
Sciatica is a disabling condition that affects many people. This condition has an enormous influence on the social functioning of patients.
- Trial name
- 5R-STS-III (NCT04660656)
- Testing
- 5 repetition sit-to-stand test
- Where
- 2 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Bergman Clinics
Infant Nutrition Disorders, Health Behavior
Sharing Histories: Test of a Teaching Method for Community Health Workers
The purpose of this study is to determine the effectiveness of an innovative methodology for training Community Health Workers that will improve their effectiveness in educating mothers to adopt best practice health behaviors in…
- Trial name
- NCT02903602
- Testing
- Sharing Histories training method for CHW, Standard training method for CHW
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Future Generations Graduate School
Plasmodium Falciparum Malaria
Rapid Diagnostic Tests for Assessment of Initial Clearance and Detection of Recurrent Malaria Infections
The aim of the study was to follow clearance of malaria infections and detection of new malaria episodes after initiation of antimalarial treatment in Tanzanian children.
- Trial name
- NCT01843764
- Testing
- HRP2 and LDH based rapid diagnostic tests for P.falciparum
- Where
- 2 sites in Tanzania
- Volunteers
- 53 people
- Sponsor
- Anders Björkman
Hemophilia A
Study Evaluating ReFacto in Hemophilia A
To identify the causative mutations in previously untreated patients with hemophilia A enrolled in the ReFacto® clinical safety and efficacy study CTN 93-R833-0XX/C9741-28, using two established hemophilia mutation testing…
- Trial name
- NCT00038909
- Testing
- BDDrFVII
- Volunteers
- 103 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Double Leg Vertical Jump (DLVJ), Single Leg Squat (SLS)
ESSKA/ESMA ACL Injury Prevention Program in Czech Sport
This study aims to address the rising incidence of ACL injuries, particularly among adolescents, by developing and implementing a comprehensive prevention program based on the evidence-based "ACL Prevention for ALL" framework…
- Conditions
- Double Leg Vertical Jump (DLVJ), Single Leg Squat (SLS), Single Leg Drop Landing (SLDL), Drop Jump Test (DJ Test)
- Trial name
- NCT07019727
- Testing
- ESSKA/ESMA 'ACL Prevention for All' methodology
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Cervical Cancer
Results Comparison of Cervical Cancer Early Detection Using Cerviray With VIA Test
Cervical cancer, primarily caused by Human Papilloma Virus (HPV), is a significant global health concern, ranking as the fourth most common cancer in women worldwide.
- Trial name
- NCT06518070
- Testing
- Cerviray AI
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
SARS-CoV-2, Influenza A
POC Performance Evaluation of LumiraDx SARS-CoV-2 Ag Ultra and SARS-CoV-2 & Flu A/B Tests.
This is a prospective multicenter study conducted to evaluate the performance of the LumiraDx SARS-CoV-2 Ag Ultra test in detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and LumiraDx SARS-CoV-2 \& Flu A/B…
- Conditions
- SARS-CoV-2, Influenza A, Influenza B, COVID-19
- Trial name
- PURSUE (NCT05728970)
- Testing
- LumiraDx SARS-CoV-2 Ag Ultra, LumiraDx SARS-CoV-2 & Flu A/B
- Where
- 10 sites in United States
- Volunteers
- 716 people, healthy volunteers welcome
- Sponsor
- LumiraDx UK Limited
Adolescent Drinking, Adolescent Substance Use
Optimizing and Advancing SBIRT in Schools
The goal of this clinical trial is to establish whether brief interventions for alcohol use can be delivered in schools for both indicated prevention and selected prevention, determine if an expanded workforce is an effective…
- Conditions
- Adolescent Drinking, Adolescent Substance Use, Risk Behavior, Health
- Trial name
- OASIS (NCT06206161)
- Testing
- Indicated Prevention, Clinical Staff, Selective Prevention, Expanded Paraprofessional Workforce
- Where
- United States
- Volunteers
- 21,000 people
- Sponsor
- Massachusetts General Hospital
Microdeletion Syndromes, Trisomy 21
Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA
The purpose of this study is to collect blood from families with a child who has been diagnosed with a chromosomal disorder including microdeletions in order to further develop a non-invasive prenatal screening test based on…
- Conditions
- Microdeletion Syndromes, Trisomy 21, Trisomy 18, Trisomy 13
- Trial name
- Microdel Triad (NCT02109770)
- Where
- 2 sites in United States
- Volunteers
- 216 people
- Sponsor
- Natera, Inc.
Childhood Absence Epilepsy, Juvenile Absence Epilepsy
A Study to Test the Long-term Safety and Tolerability of Brivaracetam in Study Participants With Childhood Absence Epilepsy or Juvenile Absence Epilepsy
The purpose of the study is to investigate the long-term safety and tolerability of brivaracetam in study participants with childhood absence epilepsy or juvenile absence epilepsy.
- Trial name
- NCT06315322
- Testing
- Brivaracetam Film-coated tablet, Brivaracetam oral solution
- Where
- 11 sites in United States, Georgia and 3 more
- Volunteers
- 70 people
- Sponsor
- UCB Biopharma SRL
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