Clinical trials: Thinness
Neurodevelopment Outcome, Linear Growth
Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study
MEDHA is a randomized controlled trial among 10-18 year old girls to examine the use-case of the United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) multiple micronutrient supplement (MMS)…
- Conditions
- Neurodevelopment Outcome, Linear Growth, Micronutrient Status, Bone Mineral Density
- Trial name
- MEDHA (NCT07695883)
- Testing
- Iron (60 mg)- folic acid (400 ug) [IFA], Multiple micronutrient supplement [MMS], Multiple micronutrient supplement Plus [MMS+]
- Where
- Bangladesh
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Undernutrition
Effectiveness of Small-Quantity vs Medium-Quantity Lipid-Based Nutrient Supplements for Prevention of Undernutrition in Young Children
Nutrition is essential for a child's growth, brain development, and protection from disease. While breastmilk provides the best nutrition for young infants, children older than six months may not get all the nutrients they need…
- Trial name
- NCT07451951
- Testing
- Medium-quantity lipid-based nutrient supplement (MQ-LNS), Small-quantity lipid-based nutrient supplement (SQ-LNS)
- Where
- 2 sites in Pakistan
- Volunteers
- 1,568 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Malnutrition, Malnutrition, Child
Double Duty Interventions and Its Impact on Double Burden of Malnutrition in Children Under Five Years
Background: Double burden of malnutrition is an emerging public health problem among children under-five years due to the inevitable consequences of nutritional transition.
- Conditions
- Malnutrition, Malnutrition, Child, Obesity, Undernutrition
- Trial name
- DBM (NCT05791305)
- Testing
- double duty intervention packages
- Where
- 2 sites in Ethiopia
- Volunteers
- 456 people
- Sponsor
- Debre Berhan University
Multiple Sclerosis
Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis
To evaluate the safety and efficacy of fingolimod vs. interferon beta-1a i.m. in pediatric patients with multiple sclerosis (MS)
- Trial name
- NCT01892722
- Testing
- Interferon beta-1a, Fingolimod
- Where
- 73 sites in United States, Australia and 23 more
- Volunteers
- 240 people
- Sponsor
- Novartis Pharmaceuticals
Childhood Cancer
Underweight, Overweight, and Linear Growth of Childhood Cancer Patients - the Growth Study
The Growth study investigates nutritional status, BMI, and linear growth trajectories from birth to adulthood in childhood cancer patients and survivors.
- Trial name
- Growth (NCT07750444)
- Where
- 11 sites in Switzerland
- Volunteers
- 12,150 people
- Sponsor
- Fabiën Belle
Childhood Obesity, Overweight (BMI > 25)
Weight Status, Resilience, and Quality of Life in Indian Children
A school-based cross-sectional study that aims to generate context-specific evidence on how weight status is related to resilience, health behaviour, and quality of life among Indian adolescents.
- Conditions
- Childhood Obesity, Overweight (BMI > 25), Underweight
- Trial name
- NCT05648045
- Where
- 16 sites in India
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Neurodevelopment, Child Growth
Building Opportunities for Nurturing Care to Enhance Child Development in Eastern and Southern Africa
The goal of this randomized controlled trial is to adapt and test a package of interventions to provide nurturing care for children aged 0-2 years in three countries (Botswana, Kenya, Zimbabwe).
- Trial name
- BONDS (NCT07430826)
- Testing
- Friendship Bench, Infant and Young Child Feeding (IYCF) Curriculum, Play-Based Curriculum
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University of Washington
ARFID, Picky Eating
Chompions! A Treatment Study for Childhood Avoidant/Restrictive Food Intake Disorder (ARFID)
Avoidant Restrictive Food Intake Disorder (ARFID) is a disorder that affects toddlers, children, adolescents, and adults. Individuals with ARFID are not able to consume an adequate amount or variety of food to a degree that it…
- Conditions
- ARFID, Picky Eating, Eating Disorders in Children
- Trial name
- NCT05105308
- Testing
- Family Assisted Diet (FAD), Feeling and Body Investigator_ARFID Division (FBI-ARFID)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Duke University
Overweight Adolescents, Underweight
Building Healthy Food Environment in Schools: Evaluating Co-created Interventions in Low Resource Settings. #BetterNutrition4Adolescent
The goal of this clinical trial is to learn if a multicomponent nutrition program developed together with the students, parents, teachers and canteen operators will improve nutrition status of adolescents.
- Conditions
- Overweight Adolescents, Underweight, Obese Adolescents
- Trial name
- NCT07332676
- Testing
- Multicomponent school nutrition intervention, Usual nutrition program
- Where
- 2 sites in India, Nepal
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Malnutrition, Stunting
Child Health, Nutrition and Microbiome Development
Childhood malnutrition is a global public health issue with devastating consequences on the health, well-being, and psychosocial development of children.
- Conditions
- Malnutrition, Stunting, Wasting, Underweight
- Trial name
- CHAMP (NCT05793294)
- Where
- 2 sites in Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Growth Problem, Low Weight
Evaluating the Effect of Nutritional Supplementation on Growth of Short and Lean Adolescents Girls
Study design: Double blind, randomized, placebo controlled study. Participants will be randomly assigned either to the intervention group or the placebo control group.
- Trial name
- NCT02397200
- Testing
- Nutritional supplementation standardized formula
- Where
- 3 sites in Israel
- Volunteers
- 99 people
- Sponsor
- Rabin Medical Center
Shock Hypovolemic, Shock, Septic
Management of Shock in Children With SAM or Severe Underweight and Diarrhea
Diarrhea is one of the leading causes of under-five childhood mortality and accounts for 8% of 5.4 million global under-5 deaths.
- Conditions
- Shock Hypovolemic, Shock, Septic, Blood Transfusion, Adrenaline
- Trial name
- NCT04750070
- Testing
- Blood and Dopamine, Blood and adrenaline
- Where
- Bangladesh
- Volunteers
- 135 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Underweight, Paediatrics
Impact of Bi-26 Supplementation on Weight Gain in Underweight Infants
The burden of disease experienced by underweight children is significant, particularly in low- and middle-income countries. Gut dysbiosis, an imbalance in microbial composition, is thought to play a role in nutrient malabsorption…
- Trial name
- NCT05952076
- Testing
- B. infantis Bi-26
- Where
- 5 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Gates Medical Research Institute
Undernutrition, Stunting
The Effectiveness of HBM-based Education Program on Improve Knowledge and Behaviors
The randomized controlled trial design with one intervention arm (nutrition education and complementary feeding) and one control (usual care) arm (1:1 ratio).
- Conditions
- Undernutrition, Stunting, Wasting, Underweight
- Trial name
- NCT05517395
- Testing
- health nutrition education, usual care
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Underweight, Stunting
Energy Regulation and Nutritional Status of Children: A Satiation Study
This is study among children attending child welfare clinics in Greater Accra Region of Ghana. The investigators want to find out if moderately malnourished children regulate the food energy intake similarly to healthy children…
- Conditions
- Underweight, Stunting, Healthy
- Trial name
- NCT05346549
- Testing
- High energy preload, Low energy preload
- Where
- Ghana
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Ghana
Acute Malnutrition in Infancy, Acute Malnutrition in Childhood
ComPAS Low-WAZ RCT Mali
Admissions criteria which treat children with only low mid-upper arm circumference (MUAC) or children with low weight-for-height z-score (WHZ) are not aligned with the evidence on which children are at risk of mortality.
- Conditions
- Acute Malnutrition in Infancy, Acute Malnutrition in Childhood, Underweight
- Trial name
- NCT05248516
- Testing
- Simplified dose of ready-to-use therapeutic food (RUTF), Standard dose of ready-to-use therapeutic food (RUTF), No nutritional treatment
- Where
- 11 sites in Mali
- Volunteers
- 1,500 people
- Sponsor
- International Rescue Committee
Malnutrition; Degree, Moderate, Diet Habit
The Effect of Double Duty Interventions on Double Burden of Malnutrition Among School Adolescents in Ethiopia
The goal of this cluster randomized controlled trial is to determine the effect of double duty interventions on double burden of malnutrition, dietary diversity score, and frequency of morbidity among secondary school adolescents…
- Conditions
- Malnutrition; Degree, Moderate, Diet Habit, Undernutrition, Overnutrition
- Trial name
- DBM (NCT05574842)
- Testing
- Double duty interventions using nutrition behavior change communication approach
- Where
- Ethiopia
- Volunteers
- 742 people
- Sponsor
- Debre Berhan University
Underweight, Wasting
Preventing Infant Malnutrition With Early Supplementation
Background: Worldwide, more than 50 million children under 5 years of age are wasted (weight-for-length/height Z-score (WLZ) <-2) and over 150 million children under 5 are stunted (length/height-for-age Z-score (LAZ) <-2); such…
- Conditions
- Underweight, Wasting, Stunting, Breastfeeding
- Trial name
- PRIMES (NCT04704076)
- Testing
- ESVS, Exclusive breastfeeding
- Where
- 2 sites in Guinea-Bissau, Uganda
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Overweight, Childhood, Obesity, Childhood
Prevalence of Obesity and Overweight in Primary School Children in the Rhein-Neckar Region in Germany
The study will determine the weight status in primary school children in the Rhein-Neckar Region in Germany and will analyse the development of height and weight in these children during the time of COVID-19 related restrictions…
- Conditions
- Overweight, Childhood, Obesity, Childhood, Child Development, Overweight and Obesity
- Trial name
- NCT05077059
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Adipositasnetzwerk Rhein-Neckar e.V.
Congenital Heart Defects, Underweight
Nutrition In Preoperative Pediatric Congenital Heart Disease
Introduction: The use of a nutritional protocols provides the standardization of assessment procedures and the optimization of nutritional status recovery of pre-surgical infants with Congenital Heart Disease (CHD).
- Trial name
- NCT05457712
- Testing
- protocol, Control
- Volunteers
- 118 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul