Clinical trials: Third Degree Burns
Burn Wound, Second- or Third-degree Burn
MSCs for the Treatment of Burn Wounds
The goal of this study is to evaluate the capacity of allogenic mesenchymal stromal cells form bone marrow (BM-MSC) or adipose tissue(Ad-MSC) to induce wound healing in patients with burn wounds.
- Trial name
- NCT06103409
- Testing
- Implantation of allogeneic MSCs on burn wounds
- Where
- Venezuela
- Volunteers
- 50 people
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Traumatic Skin Loss, 2nd and 3rd Degree Burn, Post Tumour Excision - Raw Areas Undergoes Split- Thickness Skin Grafts
Evaluation of the Use of Minced Skin Grafts for Promoting Donor Site Wound Healing After Split-Thickness Skin Grafting
Split-thickness skin grafting (STSG) is one of the most commonly performed procedures to achieve wound closure. Most studies are concerned on improving the appearance of scars and shortening the healing time of the recipient…
- Trial name
- NCT06488612
- Testing
- Minced skin grafts for donor site
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Burns, Ascorbic Acid Deficiency
Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C
Burn injury is marked by a large release of inflammatory mediators which disrupt the normal capillary barrier and cause a rapid shift of intravascular fluid into interstitial spaces, ultimately leading to shock and death.
- Conditions
- Burns, Ascorbic Acid Deficiency, Burn Shock, Burn Degree Second
- Trial name
- NCT05612867
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Arrowhead Regional Medical Center
Burn Degree Second, Burn Degree Third
The Use of Cultured (Dermal) Epithelial Autografts in Severely Burned Patients
The Swisskera project is a multicenter follow-up study at the three Swiss burn centers evaluating long-term outcomes after burn wound coverage with lab-grown epithelial grafts, specifically cultured epithelial autograft (CEA)…
- Conditions
- Burn Degree Second, Burn Degree Third, Skin Transplantation, Full Thickness Skin Defects
- Trial name
- Swisskera (NCT07415577)
- Testing
- Standard of Care (SOC)
- Where
- 3 sites in Switzerland
- Volunteers
- 236 people
- Sponsor
- University Children's Hospital, Zurich
Thermal Burn
Use of NexoBrid for Treatment of Acute Deep Partial and Full Thickness Burn Injuries
Enzymatic eschar removal with NexoBrid allows initiating and completing the phase of removal of the offending eschar earlier upon admission, enabling earlier visualization of the wound bed for assessment of burn wound depth as…
- Trial name
- NEXT (NCT04040660)
- Testing
- NexoBrid
- Where
- 28 sites in United States
- Sponsor
- MediWound Ltd
Second or Third Degree Burns
Acute and Long-Term Outcome Investigations of Fenofibrate on Severely Burned Patients
The purpose of this study is to learn the following: whether long-term treatment (6 months) with fenofibrate will decrease burn related sugar and fat increased in the blood and help prevent muscle loss and improve wound healing.
- Trial name
- NCT01574131
- Testing
- Fenofibrate, Sugar Pill
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Third Degree Burns
Comparing Modified Meek and Mesh Techniques
This is a clinical trial study that compare two plastic surgery techniques in patients with third degree of burning and both techniques are used in all patients but in different areas of burning sites of the patients.
- Trial name
- NCT02285517
- Testing
- modified Meek skin grafting technique, mesh skin grafting technique
- Volunteers
- 20 people
- Sponsor
- Shahraki, Babak N., M.D.
Full Thickness Burn
Permeaderm Versus Homograft for Full-thickness Burns
Frozen Human Cadaver Allograft (FHCA) is, nowadays, the gold standard for temporary coverage of excised full-thickness burns, but is also very expensive and requires additional personnel and major storage spaces in comparison to…
- Trial name
- NCT04673435
- Testing
- PermeaDerm for temporary coverage, FHCA for temporary coverage, PermeaDerm over autograft
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston