Clinical trials: Third Molar Extraction
Third Molar
Positional Changes of Mandibular Molar After Orthodontic Treatment
This retrospective study was carried out on pre and posttreatment digital standardized panoramic radiographs of 30 cases previously orthodontically treated with four first premolar extraction.
- Trial name
- NCT06933979
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Fayoum University
Post-operative Pain
Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study
The objective is to assess the efficacy and tolerability of a combination of 400 mg ibuprofen plus 1000 mg acetaminophen, 200 mg ibuprofen plus 500 mg acetaminophen compared with Nurofen Plus® and Panadeine® Extra.
- Trial name
- NCT01229449
- Testing
- Ibuprofen/acetaminophen, Ibuprofen/acetaminophen (higher dose), Nurofen Plus®
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- Reckitt Benckiser LLC
Stomatognatic, Tooth Diseases
Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal
Background: The third molars (wisdom teeth) normally grow in during late adolescence or early adulthood. Many people need or choose to have these teeth removed with oral surgery.
- Conditions
- Stomatognatic, Tooth Diseases, Diseases, Tooth
- Trial name
- NCT01805869
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Tooth Extraction, Molar, Third
Acupuncture on Anxiety and Inflammatory Events Following Surgery of Mandibular Third Molars
The aim of this study was to compare the effect of acupuncture and placebo acupuncture for the control of pain, edema, and trismus following the extraction of third molars and control of preoperative anxiety.
- Conditions
- Tooth Extraction, Molar, Third, Pain, Postoperative, Trismus
- Trial name
- NCT03545022
- Testing
- Acupuncture
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Third Molars Extraction
Improvement of Operating Room Efficiency in Bilateral Wisdom Teeth Surgery
This study aims to assess and compare the implementation of this comprehensive program in patients undergoing bilateral third molar extraction on OR and hospital efficiency and patient experience.
- Trial name
- PREPARE (NCT06873152)
- Testing
- Control preoperative program, Advanced preoperative program
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- Jessa Hospital
Pain
Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain
This study will compare the analgesic efficacy of a single-dose of a novel ibuprofen formulation to placebo and acetaminophen in the treatment of post-surgical dental pain following "wisdom" tooth (third molar) removal.
- Trial name
- NCT01216163
- Testing
- Novel Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- Pfizer
Pain, Oral Surgery
Pulsed Electromagnetic Fields for Postoperative Pain: a Linical Trial in Humans
This randomized clinical trial was designed to assess the clinical efficacy of Pulsed electromagnetic field PEMF delivered with a wearable device in terms of postoperative pain and quality of healing after mandibular third molar…
- Conditions
- Pain, Oral Surgery, Third Molar Extraction
- Trial name
- NCT02273999
- Testing
- RecoveryRx™
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Third Molar Impaction
The Effect of Different Treatment Modalities of Class II Malocclusion on Upper Third Molars.
What is the effect of the different treatment modalities (distalization versus upper premolar extraction) of class II malocclusion on the position, inclination and incidence of impaction of the upper third molars?
- Trial name
- NCT06098885
- Testing
- extraction orthodontic treatment
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain
Evaluation of a TNF-Alpha Modulator for Clinical and Molecular Indicators of Analgesic Effect
This study will evaluate the role of thalidomide, a tumor necrosis factor (TNF)-alpha modulator, on severe inflammation and relief of pain following extraction of wisdom teeth.
- Trial name
- NCT00121563
- Testing
- Thalidomide, Ibuprofen or Diazepam
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Nursing Research (NINR)
Impacted Mandibular Third Molar
Comparison of Electrocautery and Scalpel Blade Incisions of Impacted Mandibular Third Molars
This randomized controlled trial aims to compare electrocautery and scalpel blade incisions during surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07723326
- Testing
- scalpel blade incision, electrocautery incision
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Riphah International University
Tooth, Impacted, Tooth Diseases
Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars
This is a single centre, three-arm randomised, double-blind, double-dummy, parallel group, single-dose, active and placebo-controlled efficacy and pharmacokinetics/ pharmacodynamics study to evaluate the efficacy and safety of 2…
- Conditions
- Tooth, Impacted, Tooth Diseases, Stomatognathic Diseases
- Trial name
- NCT05484401
- Testing
- Ibuprofen 200Mg Oral Cap, Ibuprofen 200Mg Oral Tablet
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Impacted Mandibular Third Molar Extraction
Piezo-surgery Technique and Intramuscular Dexamethasone Injection to Reduce Postoperative Pain After Impacted Mandibular Third Molar Surgery
The purpose of my study is to test the effect of using piezosurgery and dexamethasone injection in the surgical extraction of impacted mandibular third molars, on Postoperative Pain.
- Trial name
- NCT04889781
- Testing
- Dexamethasone injection, Piezosurgery, Conventional Rotatory instruments
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Military Healthcare - Oral and Maxillofacial Surgery Department
Tooth, Impacted
Bradykinin Receptors and Pain
This study will examine whether bradykinin receptors are produced at the site of wisdom tooth extraction and if they contribute to the amount of inflammation and pain that follows surgery.
- Trial name
- NCT00083356
- Testing
- Wisdom tooth extraction
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Nursing Research (NINR)
Tooth Disease, Piezoelectric Technique
Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar
The main objective of the study is to compare the effects of the piezoelectric surgery and the traditional technique on soft tissue edema in patients undergoing bilateral germectomy of mandibular third molars
- Conditions
- Tooth Disease, Piezoelectric Technique, Tooth Impacted, Tooth Extraction Status Nos
- Trial name
- Germectomy (NCT06778590)
- Testing
- Piezoelectric technique in third molar germectomy, Traditional technique in third molar germectomy
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Bleeding, Tooth Extraction
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Tranexamic acid (TXA) is an effective hemostatic agent used to reduce blood loss and the need for transfusion. It is a relatively safe drug with minimal significant side effects.
- Trial name
- NCT06806241
- Testing
- Tranexamic acid, saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Wisdom Tooth Avulsion
Non-closure of Alveoli After Avulsion of Wisdom Teeth
The main objective of this study is to evaluate postoperative pain (measured by visual analogue scale (VAS) on day 2 post surgery) in patients operated for avulsion of four wisdom teeth under general anesthesia and for whom the…
- Trial name
- AlvéCare (NCT02583997)
- Testing
- Suturing of lower alveoli, Non suturing of lower alveoli
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pain, Postoperative, Substance Use
iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery
This is a clinical trial that will evaluate the feasibility and acceptability of a virtual brief program for adolescents and young adults undergoing wisdom tooth extraction and their parents.
- Trial name
- iPAWS (NCT07731295)
- Testing
- iPAWS, Educational Materials
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brown University
Third Molars Extraction
A Comparison Between Conventional Surgery and Piezosurgery
Evaluation of the effect of conventional and piezo-surgery on the secretion of Heat Shock Protein (HSP70) and on the vial bone cells at the peripheral bone cut sides after the removal of impacted mandibular third molars on both…
- Trial name
- NCT02495207
- Testing
- Piezosurgery
- Where
- Syria
- Volunteers
- 15 people
- Sponsor
- Damascus University
Facial Pain
Capsaicin to Control Pain Following Third Molar Extraction
This study will test the effectiveness of the drug capsaicin in controlling pain after third molar (wisdom tooth) extraction. Capsaicin, the ingredient in chili peppers that makes them "hot," belongs to a class of drugs called…
- Trial name
- NCT00008476
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Class II Malocclusion
Effect of Maxillary Third Molar Extraction vs. Non-extraction on Distalization of First Molars in a Group of Adolescent Patients
There is a scarcity in literature regarding the influence of maxillary third molar on distalization . This study aimed to compare the influence of unerupted maxillary third molars and their extraction on the bilateral…
- Trial name
- NCT05647720
- Testing
- Distalization combined with upper third molars extraction, Distalization without upper third molars extraction
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt