Clinical trials: Throat Infection
Postoperative Nausea and Vomiting, Sore-throat
Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.
- Conditions
- Postoperative Nausea and Vomiting, Sore-throat, Dental Caries
- Trial name
- NCT06169306
- Testing
- throat pack
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Heart Rate Monitoring, Vagal Bradycardia
Heart Rate Variability and Early Cytokine Profile in Pediatric Adenotonsillectomy
This prospective observational cohort study will assess whether perioperative short-term heart rate variability (HRV) indices and early inflammatory cytokine levels are associated with respiratory and cardiac adverse events in…
- Conditions
- Heart Rate Monitoring, Vagal Bradycardia, Adenotonsillar Hypertrophy, Tonsillitis; Hypertrophic
- Trial name
- NCT07719439
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Duzce University
Nasopharyngeal Carcinoma
Diagnostic Accuracy of EBV C Promoter Methylation Kit in Nasopharyngeal Carcinoma
This clinical study aims to evaluate the diagnostic performance of a new Epstein-Barr virus (EBV) C promoter methylation detection kit.
- Trial name
- NCT06445088
- Testing
- VCA-IgA, EBNA1-IgA, and EBV-DNA, EBV C Promoter Methylation Detection in nasopharyngeal swab samples
- Where
- 5 sites in China
- Volunteers
- 908 people
- Sponsor
- Sun Yat-sen University
Streptococcal Pharyngitis
Rapid POC GAS Diagnostics in the Paediatric ED
Randomized trial evaluating effectiveness of rapid point-of-care molecular GAS diagnostics as compared to standard culture-based techniques for the management of children aged 3-18 years of age presenting with sore throat to…
- Trial name
- NCT04247243
- Testing
- Rapid testing, Reference testing
- Where
- Canada
- Volunteers
- 392 people
- Sponsor
- Hamilton Health Sciences Corporation
Acute Respiratory Tract Infection, Otitis Media
Broad Implementation of Outpatient Stewardship
Reducing inappropriate antibiotic use is a key strategy to mitigate antibiotic resistance and adverse health effects associated with antibiotic exposure.
- Conditions
- Acute Respiratory Tract Infection, Otitis Media, Pharyngitis, Acute Sinusitis
- Trial name
- BIOS (NCT05127161)
- Testing
- Broad Implementation of Outpatient Stewardship (BIOS) intervention
- Where
- 5 sites in United States
- Volunteers
- 1,032 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Group A Streptococcal Infection
Performance of Ellume·Lab Group A Strep Test Versus Culture for the Rapid Detection of Group A Streptococcus in Patients With Acute Pharyngitis.
Participants who meet the eligibility criteria and who consent to participation or whose parents/legal guardian consent to their participation, will be enrolled in the study for a period of up to 14 days.
- Trial name
- NCT03171350
- Testing
- ellume.lab Group A Streptococcus Test
- Where
- 8 sites in Australia
- Volunteers
- 132 people
- Sponsor
- Ellume Pty Ltd
Tonsillopharyngitis, Rhinopharyngitis
Trial To Assess Efficacy and Safety of PediaFlu® in Children With Acute Tonsillopharyngitis / Rhinopharyngitis
Sore throat or acute tonsillopharyngitis, often referred to as angina catarrhalis in Central and Eastern Europe, affects mainly children, adolescents and young adults and represents one of the most common reasons to consult a…
- Trial name
- NCT04899401
- Testing
- Standard of care + PediaFlù®, Standard of care
- Where
- 3 sites in Romania
- Volunteers
- 130 people
- Sponsor
- Pediatrica S.r.l
COVID-19 Respiratory Infection, SARS-CoV2 Infection
Echinaforce COVID-19 Shedding Study
Respiratory viruses pose a permanent threat to humans and society as demonstrated by the current Covid-19 pandemic. Novel drugs and vaccines provide a means for controlling illness.
- Trial name
- NCT04999098
- Testing
- Echinaforce Forte tablets, Echinaforce Chewable tablets, Echinaforce tincture
- Where
- Bulgaria
- Volunteers
- 40 people
- Sponsor
- A. Vogel AG
Pharyngitis
Tablet vs. Liquid Suspension Ibuprofen in the Relief of Pain
Ibuprofen (also known as Advil or Motrin) is a medication that is known to reduce pain. It is also known that ibuprofen levels in the blood rise higher and faster if the medication is taken in liquid suspension.
- Trial name
- NCT01681667
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Albany Medical College
Candidiasis, Esophageal, HIV Infections
A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems
To compare the safety, tolerance, and effectiveness of fluconazole and ketoconazole in the treatment of candidal esophagitis in immunocompromised patients.
- Trial name
- NCT00002304
- Testing
- Ketoconazole, Fluconazole
- Where
- 42 sites in United States, Canada
- Sponsor
- Pfizer
Tonsillitis, Obstructive Sleep Apnea
Study of Efficacy and Adverse Effects: Vessel Sealing System Tonsillectomy Versus Cold Knife Tonsillectomy
This study was planned to compare vessel sealing system tonsillectomy (VSST) to the traditional cold knife tonsillectomy (CKT) with special regard to intraoperative bleeding, operative time, postoperative pain and hemorrhage.
- Trial name
- NCT00636402
- Testing
- Cold Knife Tonsillectomy, Vessel Sealing System Tonsillectomy
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Chulalongkorn University
Sexually Transmitted Diseases, Chlamydia
Evaluation of NAATs for Detection of C. Trachomatis and N. Gonorrhoeae From Pharynx, Rectum, Glans & Urethra of MSM
Julius Schachter, PhD, from the Department of Laboratory Medicine at UCSF, and Jeffrey Klausner, MD, from the Department of Public Health, are conducting a study to evaluate a type of test (nucleic acid amplification test) for…
- Conditions
- Sexually Transmitted Diseases, Chlamydia, Gonorrhea
- Trial name
- NCT00187902
- Where
- United States
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tonsillitis
Evaluation of Coblation Channeling in Treating Chronic Tonsillitis
The investigators wish to evaluate coblation channeling in the treatment of chronic tonsillitis.
- Trial name
- NCT01193790
- Testing
- Coblation channeling
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hillel Yaffe Medical Center
Covid19
Serological Profile of Children and Young Adolescents With at Least One COVID-19 Diagnosed Family Member
Use of rapid serological tests to assess the vulnerability to SARS-CoV-2 infection of subjects aged 4-16 years old and cohabiting with at least one family member who tested positive to SARS-CoV-2
- Trial name
- NCT04649944
- Testing
- Serological test and phone interview
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Milan
Childhood Burkitt Lymphoma, Childhood Central Nervous System Germ Cell Tumor
Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas
This phase I trial is studying the side effects and best dose of oxaliplatin when given together with irinotecan in treating young patients with refractory solid tumors or lymphomas.
- Conditions
- Childhood Burkitt Lymphoma, Childhood Central Nervous System Germ Cell Tumor, Childhood Diffuse Large Cell Lymphoma, Childhood Grade III Lymphomatoid Granulomatosis
- Trial name
- NCT00101270
- Testing
- irinotecan hydrochloride, oxaliplatin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Cancer Institute (NCI)
Laryngopharyngeal Reflux, Throat Pain
Anti-reflux Control to Decrease Post Tonsillectomy Pain
The study aims to determine if treating pediatric patients (age 7-17) for four weeks with omeprazole prior to tonsillectomy will decrease post tonsillectomy pain.
- Trial name
- NCT01777854
- Testing
- Omeprazole
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Covid19
Prevalence of SARS -Cov2 Carriage in Asymptomatic and Mildly-symptomatic Children
This study is expected to provide, for the first time, data on Cov2-SARS circulation in asymptomatic children and children with moderate respiratory symptoms in order to construct the severity pyramid of this novel pathogen.
- Trial name
- COVILLE (NCT04318431)
- Testing
- Data collection and rhinopharyngeal swab
- Where
- 22 sites in France
- Volunteers
- 605 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Tonsillitis Streptococcal
Comparison of Intravenous Co-amoxiclav Versus Benzyl Penicillin
To compare intravenous Co-amoxiclav versus Benzyl penicillin in children with severe streptococcal tonsillitis in terms of efficacy, safety and cost effectiveness.
- Trial name
- NCT04215770
- Testing
- inj co-amoxiclav 50 units/kg/day vs inj Benzyl Penicillin 25000 units/kg/day
- Where
- Pakistan
- Volunteers
- 310 people
- Sponsor
- Combined Military Hospital, Pakistan
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Nasopharyngeal Carcinoma
Carboplatin and Docetaxel Followed by Epstein-Barr Virus Cytotoxic T Lymphocytes
Patients have a type of cancer called nasopharyngeal carcinoma (NPC) that has either come back or not gone away after the best known standard treatments.
- Trial name
- CADEN (NCT00953420)
- Testing
- Docetaxel, Carboplatin, Dexamethasone
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine