Clinical trials: Thrombolysis
Myocardial Infarction
APRICOT-3: Antithrombotics in the Prevention of Reocclusion In COronary Thrombolysis -3
Reocclusion of the infarct artery is observed in about 30% of patients within three months after successful thrombolysis for acute myocardial infarction (MI).
- Trial name
- NCT00138034
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- Netherlands
- Volunteers
- 49 people
- Sponsor
- Heartcenter, University Medical Center St. Radboud
Deep Vein Thrombosis, Post-Thrombotic Syndrome
Pediatric High-Risk Deep Venous Thrombosis Lytic Outcomes Trial
The purpose of this study is to determine if the use of adjunctive catheter-directed thrombolysis (CDT), which includes the intrathrombus administration of rt-PA (Activase/Alteplase), can prevent post-thrombotic syndrome (PTS) in…
- Conditions
- Deep Vein Thrombosis, Post-Thrombotic Syndrome, Venous Thrombosis
- Trial name
- PHLO (NCT02767232)
- Testing
- Recombinant tissue plasminogen activator (rt-PA), Standard Anticoagulation Therapy
- Sponsor
- University of Colorado, Denver
Stroke, Acute
Computer-based Online Database of Acute Stroke Patients for Stroke Management Quality Evaluation
In the past three decades, the burden of stroke has increased in China and has gradually become the leading cause of death. The data acquisition and medical quality management still need to be improved in China.
- Trial name
- NCT04487340
- Testing
- Education
- Where
- China
- Volunteers
- 200,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pulmonary Embolism, Venous Thromboembolism
STRATEGY-PE: Real-World Treatment Strategies for Intermediate-High Risk Pulmonary Embolism
This study aims to compare the effectiveness and safety of three treatment strategies (Anticoagulation, Thrombolysis, and Mechanical Thrombectomy) for patients with intermediate-high risk acute pulmonary embolism (PE) in a…
- Trial name
- STRATEGY-PE (NCT07603700)
- Testing
- Anticoagulants, Thrombolytic Agents, Mechanical Thrombectomy Devices
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Cerebral Infarction
Study on Yangxue Nao Granules Reducing the Risk of Stroke
Objective: To explore the effectiveness of raising serum nao granules in reducing the risk of bleeding in patients with acute ischemic stroke treated with intravenous thrombolysis in the real world
- Trial name
- NCT04949906
- Testing
- Raise serum brain granules, No nourishing serum brain granules are used
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University Third Hospital
Embolism, Thrombophlebitis
Treatment for Blood Clots in the Veins of the Legs
Acute deep venous thrombosis (ADVT) of the lower extremity is a common disorder. Traditional treatment with anticoagulation therapy is effective in reducing the associated risk of pulmonary embolism, but is ineffective in…
- Trial name
- NCT00001713
- Testing
- Recombinant Tissue Plasminogen Activator, Heparin, Warfarin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Stroke
Thrombolysis in Pediatric Stroke (TIPS)
Thrombolysis in Pediatric Stroke (TIPS) is a five-year multi-center international safety and dose-finding study of intravenous (IV) tPA in children with acute ischemic stroke (AIS) to determine the maximal safe dose of…
- Trial name
- TIPS (NCT01591096)
- Testing
- Tissue plasminogen activator (Activase®)
- Where
- 15 sites in United States, Canada
- Volunteers
- 1 people
- Sponsor
- Seattle Children's Hospital
Arterial Ischemic Stroke
National Retrospective Study Of Recanalization Treatments In Pediatric Arterial Ischemic Stroke
The purpose of this study is to evaluate recanalization treatments use, safety and efficacy at the acute phase of arterial ischemic stroke in pediatric patients
- Trial name
- KID-CLOT (NCT03887143)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pulmonary Embolism
Thrombolytic and Interventional Treatment of Pulmonary Embolism
Pulmonary embolism (PE) is a pulmonary vascular disease that seriously endangers human health. It has the characteristics of high morbidity, high mortality, high misdiagnosis rate and low detection rate.
- Trial name
- NCT03886194
- Testing
- interventional treatment in pulmonary
- Where
- China
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Cerebrovascular Accident
Troponin- I Elevation Predicts Outcome After Thrombolysis in Stroke Patients
Elevated level of serum troponin (T-I) has been regarded as a prognostic biomarker of poor outcome in acute ischemic stroke. However, its role in outcome in thrombolysed ischemic stroke patients remains uncertain.
- Trial name
- NCT03925298
- Volunteers
- 81 people
- Sponsor
- Zagazig University
Acute Ischemic Stroke, Cerebral Embolism and Thrombosis
Thrombolysis and RIPC in Acute Ischemic Stroke
Remote ischemic postconditioning (RIPC) is suggested to protect the cerebral cell against ischemia in various settings. However, the effect of RIPC in patients with acute ischemic stroke who undergo thrombolysis has yet to be…
- Trial name
- tripcais (NCT03218293)
- Testing
- RIPC device (IPC-906X)
- Where
- China
- Volunteers
- 68 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Thrombolysis
The Impact of a Helicopter Emergency Medical System on Prognosis in Stroke Patients
Stroke is a leading cause of death and disability, and 15 million people suffer a stroke each year; one-third die and one-third are left permanently disabled.
- Trial name
- NCT02576379
- Volunteers
- 1,068 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Stroke
Safety and Efficacy of the Penumbra™ System in Acute Middle Cerebral Artery (MCA) Stroke
Stroke prognosis is intimately related to reperfusion. Reperfusion in acute setting can be achieved with different strategies - varying from intravenous rtPA from mechanical thrombectomy.
- Trial name
- NCT01133223
- Testing
- Penumbra™ System, Recombinant tissue plasminogen activator
- Where
- Brazil
- Sponsor
- Hospital de Clinicas de Porto Alegre
Thrombolysis, Deep Vein Thrombosis
Contemporary Endovascular Therapies in Treatment of Acute Iliofemoral Deep Vein Thrombosis
The goal of this initial proof of principle single arm cohort trial is to determine if contemporary endovascular venous intervention, compared with a 1:1 propensity-matched medical therapy arm of the ATTRACT trial, significantly…
- Trial name
- CLEAR-DVT (NCT03901872)
- Testing
- Contemporary endovascular venous intervention by Zelante pharmacomechanical thrombolysis
- Where
- United Kingdom
- Volunteers
- 65 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Acute ST-elevation Myocardial Infarction
Detection and Significance of Heart Injury in ST Elevation Myocardial Infarction.
Heart imaging with magnetic resonance imaging (MRI) provides detailed insights into heart function and injury. The nature and significance of heart injury after a heart attack is incompletely understood.
- Trial name
- BHF MR-MI (NCT02072850)
- Testing
- Coronary pressure wire, Magnetic resonance imaging of the heart
- Where
- United Kingdom
- Volunteers
- 324 people
- Sponsor
- NHS National Waiting Times Centre Board
Stroke
Finnish Telestroke Pilot 2007-2009
Objective is to describe two years experience from The Finnish Telestroke piloting between Helsinki University Central Hospital (HUCH), Department of Neurology, The Hub, and five hospitals, the spokes.
- Trial name
- NCT01136993
- Where
- Finland
- Volunteers
- 109 people
- Sponsor
- Helsinki University Central Hospital
Stroke, Transient Ischemic Attack
Copeptin for Risk Stratification in Acute Stroke Patients: the CoRisk Study
Prospective observational multicenter study to evaluate copeptin as a prognostic marker in patients with an acute cerebrovascular event.
- Trial name
- CoRisk (NCT00878813)
- Testing
- Sampling of 15ml blood, Blood-Sampling
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 1,102 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern