Clinical trials: Tooth
Dental Caries in Children
SDF Effectiveness on Arresting Caries in Children
Purpose: To assess the clinical effectiveness of silver diamine fluoride (SDF) to control asymptomatic cavitated carious lesions compared to conventional glass ionomer restoration in preschool children.
- Trial name
- NCT05872542
- Testing
- Silver Diamine Fluoride (SDF), Glass Ionomer Restoration (GI), Sodium fluoride varnish with nano-sliver particles (NaF-AgNP)
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Clinical Decision Making, Tooth Extraction
On Adequacy of Referrals to Oral and Maxillofacial Surgery
Currently, an ongoing generational shift of the dental community in Sweden originates from an increased number of retiring dentists.
- Conditions
- Clinical Decision Making, Tooth Extraction, Referral and Consultation, Surgery, Oral
- Trial name
- NCT05845437
- Where
- Sweden
- Volunteers
- 624 people
- Sponsor
- Region Skane
Caries,Dental
Comparison of the Treatment Outcomes of the Conventional Stainless Steel Crown Restorations and the Hall Technique in the Treatment of Carious Primary Molars
Stainless steel crowns have shown high success in restoring carious primary molars over a longer period of time than conventional restorations.
- Trial name
- NCT06597669
- Testing
- Placement of stainless steel crowns on primary molars
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Molar Hypomineralization, Incisor
Comparison of the Long-Term Success of Different CAD-CAM Blocks Used as Indirect Restorations in Molar Incisor Hypomineralized Teeth: A Split Mouth Study
This study is about the long-term survival success of different, externally prepared fillings (Indirect restoration, CAD-CAM blocks) used in teeth with reduced mineral structure, namely Molar Incisor Hypomineralization (MIH)…
- Trial name
- NCT07144605
- Testing
- CAD-CAM, indirect restorations
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Pulpitis Reversible, Pulp Exposure, Dental
Comparative Evaluation of Eggshell Powder in Primary Teeth Pulpotomy
To assess \& compare clinical \& radiographic effects of Eggshell Powder, Biodentine and MTA as pulpotomy agents in primary teeth.
- Trial name
- NCT05812053
- Testing
- pulpotomy, cone beam computed tomography (CBCT) assessment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Dental Caries in Children, Pit and Fissure Sealant
Progression of Active Microcavitated Carious Lesions on Primary Molar Occlusal Surfaces
Objective: To verify the progression of active microcavitated carious lesions on occlusal surfaces of primary molars after the orientation of the brushing technique associated with fluoride dentifrice compared to resin sealant…
- Conditions
- Dental Caries in Children, Pit and Fissure Sealant, Toothbrushing
- Trial name
- NCT04127357
- Testing
- 1450 ppm fluoride toothpaste brushing x Resin sealing (FluroShield, Dentsply, Brazil).
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Edentulism, Malocclusion; Displaced Teeth
Augmented Reality Dentistry
This study aims to evaluate the accuracy of augmented reality (AR)-assisted dental procedures. Patient-specific anatomical data will be acquired using cone-beam computed tomography (CBCT) and intraoral scanning and integrated to…
- Conditions
- Edentulism, Malocclusion; Displaced Teeth, TEETH EXTRACTION
- Trial name
- AugRealDent (NCT07814794)
- Testing
- Surgery, Patients requiring orthodontic treatment.
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Bruxism
Laser Versus Physiotherapy in Management of Bruxism in Children: RCS
The goal of this randomized controlled study is to compare laser acupuncture versus modified physical therapy in controlling bruxism in children.
- Trial name
- RCS (NCT06131879)
- Testing
- Laser acupuncture, Modified physical therapy
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Reversible Pulpitis
The Role of Matrix Metalloproteinases on the Primary Teeth Pulpotomy Treatments
Matrix metalloproteinases (MMPs) are important zinc enzyme group that responsible for reducing extracellular matrix components. It has been reported that MMPs play an important role in pulpal inflammation.
- Trial name
- NCT05145686
- Testing
- Matris metalloproteinase -2, -8, -9 expressions
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ege University
Caries, Dental, Caries Class I
Caries Sealing Using Giomer and Glass Ionomer Cement With or Without Silver Diamine Fluoride
The purpose of this study is to evaluate and compare the clinical performance of Giomer and GIC restorations with and without SDF on caries sealing of primary molar teeth
- Trial name
- NCT03872986
- Testing
- SDF, Giomer, GIC
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Plaque, Oral Hygiene
Comparison of Model-Based and Video-Based Toothbrushing Instruction in Children
Good toothbrushing is important for keeping children's teeth healthy. Dentists commonly teach children how to brush their teeth using dental models or instructional videos.
- Trial name
- NCT07909213
- Testing
- Video-Based Toothbrushing Instruction, Model-Based Toothbrushing Instruction
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Tooth, Nonvital
Endodontic Regenerative Procedure for Immature Non-vital Teeth
In this clinical trial the investigators will evaluate an alternate treatment option, which was developed for teeth with incomplete roots, called Regenerative Endodontic Procedure (REP).
- Trial name
- NCT03425123
- Testing
- Regenerative Endodontic Procedure (REP)
- Where
- United States
- Sponsor
- Boston University
Apical Periodontitis
Comparison of Sonic and Ultrasonic Activation on Healing of Apical Periodontitis
The goal of this clinical trial is to learn whether two different irrigation activation methods - passive ultrasonic irrigation (PUI) and sonic activation - help periapical healing in root canal treatments of single-rooted teeth…
- Trial name
- SONIC-ULTRA (NCT07249450)
- Testing
- Sonic Activation Irrigation, Passive Ultrasonic Irrigation (PUI), Conventional Needle Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hilal Çuhadar Beşiroğlu
Pain, Postoperative
Intraoperative Pain After Infiltration Technique Using Artpharma Versus Artinibsa in Children
The aim of this study is to assess Intraoperative pain for extraction of Maxillary primary molars using Artpharma Versus Artinibsa in children during infiltration technique.
- Trial name
- NCT04221685
- Testing
- Artpharma, Artinibsa
- Volunteers
- 130 people
- Sponsor
- Cairo University
Fissure Sealants, Oral Hygiene Orientation
Efficacy of Sealants in Cavitated Enamel Lesions on Occlusal Surfaces in Children
The aim of this study is to evaluate the efficacy of oral hygiene orientation singly, compared to resin-based sealants in controlling occlusal cavitated enamel lesions on primary and permanent molars.
- Trial name
- SLM1661 (NCT02617940)
- Testing
- fissure sealant, oral hygiene orientation
- Where
- Brazil
- Volunteers
- 546 people
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Bone Loss, Alveolar
L-PRF in Alveolar Ridge Preservation
The effect of leucocyte- and platelet-rich fibrin (L-PRF) for enhancing the healing after dental extractions is still a matter of debate.
- Trial name
- L-PRF (NCT03408418)
- Testing
- Platelet-rich fibrin
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Oral Health
A Model-based Health Education Program to Improve Oral Health in School Going Children
This was a randomized controlled trial to assess how an education program based on health belief model (HBM) may affect oral health status in the elementary school going children.
- Trial name
- NCT05112224
- Testing
- Education program based on health belief model to improve oral health
- Where
- Iran
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Baqiyatallah Medical Sciences University
Leukodystrophy, White Matter Disease
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophies, and other heritable disorders of the white matter of the brain, were previously resistant to genetic characterization, largely due to the extreme genetic heterogeneity of molecular causes.
- Conditions
- Leukodystrophy, White Matter Disease, 4H Syndrome, Adrenoleukodystrophy
- Trial name
- NCT02699190
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Philadelphia
Periapical Periodontitis
Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration.
To compare the dental survival in a period of one year of mature permanent teeth with apical lesion following the administration of encapsulated Mesenchymal Stem Cells under a regenerative endodontic procedure and a conventional…
- Trial name
- RanoKure (NCT03102879)
- Testing
- Regenerative Endodontic Procedure, Conventional Root Canal Treatment
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Universidad de los Andes, Chile
Dental Occlusion, Traumatic
Influence of Dental Occlusion on the Performance of High Level Rowers (IODPR)
Monocentric, prospective, randomized, open-label, cross-over study.
- Trial name
- IODPR (NCT03648125)
- Testing
- with artificial occlusal disturbance, without artificial occlusal disturbance
- Where
- France
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
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