Clinical trials: Tooth Caries
Pulpitis in Permanent Teeth, Dental Caries Extending to Pulp
Pulp Inflammatory Markers and Outcome of Pulpotomy
This is a prospective clinical study that aims to investigate the level of inflammatory mediators in the inflamed dental pulp and its potential relationship to the outcome of full pulpotomy in mature permanent teeth with carious…
- Trial name
- pulpitis (NCT06960603)
- Testing
- Full pulpotomy
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Down Syndrome
Fluor Varnish With Silver Nanoparticles for Dental Remineralization in Patients With Trisomy 21
Patients with trisomy 21 are in greater danger of developing caries. It has been hypothesized that adding silver nanoparticles to fluor varnishes could promote remineralization of the teeth.
- Trial name
- NCT01975545
- Testing
- Fluor varnish, Fluor varnish with nanoparticles
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Dental Caries, Oral Health
Effect of Probiotics Containing Yogurts on the Composition of Biofilms in Patients Under Orthodontic Treatment
Aim: To assess in vivo if the intake of yogurt containing Bifidobacterium animalis ssp. lactis DN- 1173010 probiotic for a period of 2 weeks affects the salivary levels or biofilms of mutans streptococci and the lactobacilli of…
- Trial name
- NCT01657539
- Testing
- Yogurt containing probiotics
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Dental Caries in Children
Evaluation of the Antimicrobial Fiber Reinforced Composite Resin Space Maintainer Modified With Silver Nano Particles
Fiber reinforced composite resin space maintainer
- Trial name
- NCT05902975
- Testing
- Fiber reinforced composite resin space maintainer
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Radiographic Progression of Infiltrated Caries Lesions In-vivo
This study is investigating the efficacy of caries lesion infiltration therapy as compared to the current preventative approach for early caries lesions.
- Trial name
- ICON (NCT01496456)
- Testing
- Resin infiltration, Caries management
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Michigan
Caries Class II, Caries,Dental
Clinical Performance of Advanced Self- Adhesivee Resin Composite Hybrid Restorations.
Clinical performance according to modified USPHS criteria of advanced self-Adhesive resin composite hybrid restorations is evaluated for 1 year versus conventional resin composite restorations in posterior teeth.
- Trial name
- NCT04790383
- Testing
- Advanced Self-Adhesive resin composite hybrid restorations (Surefil one (Dentsply Sirona))., Conventional resin composite restoration. (Sphere Tec, (Dentsply Sirona
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz
Initial Dental Caries, White Spot Lesion of Tooth
Clinical Evaluation of Remineralizing Potential of Remineralizing Agents on WSLs Managment
To evaluate and compare the clinical effect of four different remineralizing agents on initial enamel caries after a two years follow up.
- Trial name
- NCT07111403
- Testing
- SAP fluoride plus, 10% n-HAp., 10% n-BAG.
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Dental Caries
Reminerlization Potential of GSE Gel versusCPP-ACP in Carious White Spot Lesions in Post Orthodontic Patients
Assess the effectiveness of applying grape seed extract (GSE) gel versus casein phosphopeptide-amorphous calcium phosphate (MI) paste on remineralization of white spot lesion (WSLs) in post orthodontic patients.
- Trial name
- NCT03966378
- Testing
- Grape seeds extract, Casein-phosphopeptide/amorphous-calcium phosphate
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental White Spots, Dental Caries
MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study
The objective of this clinical study is to evaluate the efficacy of multiple applications of MI Varnish in combination with MI Paste Plus in caries protection and remineralization in comparison to the use of a control (Crest…
- Trial name
- GC-WS (NCT02424097)
- Testing
- CPP-ACP 5% sodium fluoride varnish & 900ppm fluoride paste, 1,100pm F-toothpaste and 0.5%NaF rinse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
White Spot Lesion, Orthodontic Appliance Complication
A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.
The goal of this randomized clinical trial is to compare the influence of casein phosphopeptide amorphous calcium phosphate (CPP-ACP), CPP-ACP in combination with fluoride (CPP-ACPF), high fluoride concentration, and conventional…
- Trial name
- NCT05710874
- Testing
- CPP-ACP paste, CPP-ACPF paste, 1.25% fluoride gel
- Where
- Belgium
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Preschool Children, Dental Caries in Primary Teeth
A Comparison of Teledentistry vs Clinical Examination for Treatment Needs Assesment
Dental caries is one of the most common chronic diseases in children and may require complex dental treatment, especially in preschool-aged children.
- Trial name
- NCT07625982
- Testing
- Tele- dentistry intraoral exam
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Tooth Decay, Probiotics
Effects of Probiotics on Streptococcus Mutans ve Lactobacillus Spp
To evaluate the change of S. mutans and Lactobacillus spp. counts after all dental treatments were completed under general anesthesia and compare the groups in case of using probiotics and not using probiotics with the time for…
- Conditions
- Tooth Decay, Probiotics, Streptococcus Mutans
- Trial name
- NCT05859646
- Testing
- Probiotic use
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Didem Sakaryali Uyar
Dental Caries in Children
Efficacy of a Chemically Activated Composite Resin Alkasite in Atypical Caries Lesions of Deciduous Teeth
Atypical cavities, which involve more than two surfaces being one of them vestibular or lingual/palatine, are a challenge for restorative dentistry, since the risk of failure of the restorations are related to the number of…
- Trial name
- NCT04195386
- Testing
- Dental Restoration with Chemically activated Composite resin Alkasite, Dental Restoration with Resin-Modified Glass ionomer Cement
- Where
- Brazil
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Dental Caries, Dental Caries in Children
Restoration Repairs Using Composite Resin Versus Glass Ionomer in Primary Molars: a Randomized Clinical Trial
The objective of this randomized clinical study is to evaluate the survival of repairs in restorations using composite resin (CR) or high viscosity glass ionomer cement (GIC) in primary molars.
- Trial name
- NCT04491981
- Testing
- Encapsulated Glass Ionomer Cement, Composite resin
- Where
- Brazil
- Volunteers
- 312 people
- Sponsor
- University of Sao Paulo
Dental Caries
Clinical Performance of Bioactive Highly Filled Injectable Flowable Composite for Direct Posterior Occlusal Conservative Restorations Using FDI Criteria: Two Year Randomized Clinical Trial
The aim of this study is to evaluate Clinical Performance of bioactive highly filled injectable flowable composite for direct posterior occlusal conservative restorations using FDI Criteria
- Trial name
- NCT06790511
- Testing
- bioactive highly filled injectable flowable composite, highly filled injectable flowable composite
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries
Clinical and Radiographic Success Rate of Pulpotomy Versus Pulpectomy for Management of Primary Teeth With Deep Caries
This trial aims to compare treatment outcomes between Pulpotomy and Pulpectomy in treating vital primary teeth diagnosed with deep caries with symptoms of irreversible pulpits
- Trial name
- NCT06293521
- Testing
- Pulpotomy, Partial Pulpectomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries
Is DIAGNOcam Comparable to Bitewing Radiographs as a Diagnostic Method for Approximal Caries in Primary Teeth?
BACKGROUND: To diagnose caries in clinical practice today, a combination of clinical examination with mirror and probe, and in sometimes x-ray images are used.
- Trial name
- Diagncamera (NCT03181711)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Malmö University
Anesthesia
Neurodevelopment Outcomes After Pediatric Dental Caries Treatment Under General Anaesthesia
The purpose of this study is to investigate whether early expose to general anaesthesia will influence neurodevelopment.
- Trial name
- NCT03002792
- Testing
- general anesthesia
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Air Force Military Medical University, China
Dental Caries
Medical Management of Caries in the Primary Dentition Using Silver Nitrate
This pilot trial compares conventional restorations with a new strategy based on the medical management of caries using silver nitrate and fluoride varnish with no restorations.
- Trial name
- NCT02604134
- Testing
- Prophylaxis, Fluoride varnish, Silver Nitrate
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Arwa Owais
Dental Caries in Children
Effectiveness of Silver Diamine Fluoride in Arresting Dental Caries
The present study aims to evaluate, through a controlled clinical randomized study,the effectiveness of silver diamine fluoride in arresting dentin caries lesions in primary molars when compared to atraumatic restorative…
- Trial name
- NCT03063307
- Testing
- Atraumatic Restorative Treatment, Silver Diamine Fluoride
- Where
- Brazil
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro