Clinical trials: Tooth Disorder
CLASS II DIVISION 1 MALOCCLUSION, Class II Malocclusion
The Effectiveness of the Twin Block and Carriere Motion Appliances in Post-pubertal Patients and an Evaluation of the Impact of Class II Malocclusion and Its Correction on Oral Health-related Quality of Life
The investigators of this clinical trial aim to: Compare the effectiveness and efficiency of Clark's Twin Block Appliance (CTB) vs Carriere Motion Appliance (CMA) in correcting Class II malocclusion when used in post-pubertal…
- Conditions
- CLASS II DIVISION 1 MALOCCLUSION, Class II Malocclusion, Growth, Overjet
- Trial name
- NCT07292636
- Testing
- CTB, CMA
- Where
- Ireland
- Volunteers
- 88 people
- Sponsor
- Aslam Alkadhimi
Dental Caries
Caries of First Permanent Molars and Association With Dietary and Oral Habits Among a Group of Egyptian Children
This cross-sectional study aims to assess the prevalence of dental caries in the first permanent molars of Egyptian children aged 6 to 7 years, and to examine how this caries status relates to the children's dietary habits and…
- Trial name
- NCT07725757
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Pain, Postoperative, Dental Pain
A Study of Acetaminophen for Post Surgical Dental Pain
To assess the safety, tolerability, analgesic, efficacy and pharmacokinetics of high dose acetaminophen relative to placebo and low dose acetaminophen relative to placebo over a 24 hour period in patient experiencing moderate to…
- Trial name
- NCT04018612
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Dental Anxiety, Dental Pain and Sensation Disorder
The Effectiveness of Audiovisual Distraction Behavior Guidance Technique in Children With Dental Anxiety
This randomized, two-armed, placebo-controlled, cross-over, controlled trial aimed to evaluate the effect of virtual reality exposure therapy (VRET) on dental anxiety, pain, and behaviour among children undergoing dental…
- Trial name
- NCT04226651
- Testing
- Virtual Reality Device, Protective glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Dental Caries, Restoration Defects
Repair Versus Replacement of Failed Restorations in Primary Teeth
Dental caries affect approximately 573 million children globally, and the management of failed restorations is a frequent clinical issue in pediatric dentistry.
- Conditions
- Dental Caries, Restoration Defects, Primary Teeth
- Trial name
- NCT07813065
- Testing
- Repair of Failed Restoration, Replacement of Failed Restoration
- Where
- Brazil
- Volunteers
- 382 people
- Sponsor
- University of Sao Paulo
Immature Teeth, Necrotic Pulp
Efficacy of Integrated Nano-technology in Revascularization of Immature Necrotic Teeth
This trial aims to study the effect of photoactivated disinfection using Diod laser (810 nm) to activate photosensitive nanoparticle chitosan as an endodontic irrigant versus sodium hypochlorite followed by saline and then EDTA…
- Trial name
- NCT06631885
- Testing
- regenerative endodontic procedure using blood clot according to AAE, regenerative endodontic procedure using photo activated nanochitosan 2%
- Volunteers
- 20 people
- Sponsor
- Minia University
Dental Caries
SEALANT-DK: Longevity and Efficacy of 6 Resin Sealants Used for Sealing Permanent Teeth in Children and Adolescents
Background: Occlusal caries is the main reason for restorative therapy in the young permanent dentition, but restorations have limited survival time and may also weaken the tooth.
- Trial name
- SEALANT-DK (NCT02561689)
- Testing
- Fissure sealing
- Where
- Denmark
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Malocclusion
Evaluation of a "Flash-free" Adhesive Resin for Orthodontic Bracket Bonding
The purpose of this study is to compare bonding time, bond survival, amount of adhesive remaining on the tooth surface after bracket debonding, and time required for adhesive remnant cleanup between a new "flash-free" and a…
- Trial name
- NCT02030002
- Testing
- APC Flash-Free Adhesive Coated Appliance System, APC II Adhesive Coated Appliance System
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Molar Incisor Hypomineralisation, Molar Incisor Hypomineralization
Prevalence of Hypomineralized Second Primary Molars and Its Association with Molar-Incisor Hypomineralization.
The aim for thid study is to detect the prevalence of HSPM and the possible association between MIH and HSPM in a group of Egyptian children aged from 6-12 years.
- Conditions
- Molar Incisor Hypomineralisation, Molar Incisor Hypomineralization, Hypomineralization Molar Incisor, Hypomineralization of Enamel
- Trial name
- NCT06727539
- Volunteers
- 825 people
- Sponsor
- Cairo University
Malocclusion, Angle Class II
Effect of Low-Intensity Pulsed Ultrasound on Functional Treatment of Class II Malocclusion
This experimental study will evaluate the effect of combined treatment with low-intensity pulsed ultrasound (LIPUS) and functional appliances (twin-block) on the correction of class II malocclusion, compared with the control…
- Trial name
- NCT03251807
- Testing
- Twin-block, LIPUS (Low-intensity pulsed ultrasound)
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Periapical Periodontitis
Periapical Healing After One or Two-visits to Endodontic Treatment in Adolescents Patients
The main objective of this study is the prevention and repair of apical periodontitis in lower molars with pulp necrosis after the execution of endodontic treatment in one or two visits in adolescent patients.
- Trial name
- PHAP (NCT01312194)
- Testing
- Root canal therapy in one visit, Root Canal Therapy in two-vist
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dental Plaque
U Shaped Toothbrush in Removing Plaque in Children
The aim of this study is to evaluate the effectiveness of a U-shaped toothbrush in removing plaque in preschool children which can be a simple, acceptable, and effective way to remove plaque in children in order to improve their…
- Trial name
- NCT06288581
- Testing
- Traditional toothbrush group, U shaped toothbrush group
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Damascus University
Class II Division 1 Malocclusion
Comparison of Treatment Effects of PowerScope2 and Forsus Using CBCT
The main objective of this prospective, controlled clinical study is: 1. To compare the treatment effects of PowerScope2 and Forsus Fatigue Resistant Device in patients with Class II divison1 malocclusion. 2.
- Trial name
- NCT03296644
- Testing
- Class II correction using PowerScope2, Class II correction using Forsus
- Where
- India
- Volunteers
- 42 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Tooth Loss, Dental Implant
A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort Study
The goal of this prospective cohort study is to evaluate the clinical performance of a new generation of customized CAD/CAM pre-fabricated root-analog dental implants over a 36-month period.
- Trial name
- NCT06576284
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Focal Infection, Dental
Immediate Versus Delayed Treatment of Odontogenic Infections
The objective of this study is to compare the physiologic resolution of dental infections between immediate tooth extraction (control group) and administration of systemic antibiotics and delayed extraction (study groups 1 and…
- Trial name
- NCT04057014
- Testing
- Amoxicillin, Tooth extraction
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Class III Malocclusion
The Effects of the Chin Cup on Temporomandibular Joint and Mandibular Dimensions
This in vivo comparative study will evaluate the changes in the mandibular dimensions and the glenoid fossa after skeletal class III subjects' therapy by chincup appliance and compare it with an untreated class III control group.
- Trial name
- NCT05350306
- Testing
- Chincup, Control group
- Where
- Syria
- Volunteers
- 38 people
- Sponsor
- Damascus University
Edentulous Mouth, Complete Edentulism
Mandibular Overdentures Retained by Mini Implants: a Clinical Trial Comparing Different Surgical and Loading Protocols
This study aims to test the combined effects of different loading protocols and surgical approaches on clinical and patient-reported outcome measures (PROMs) following the use of four mini implants for mandibular overdenture…
- Trial name
- SMIS (NCT04760457)
- Testing
- Implant placement with flapped surgery, Implant placement with flapless surgery, Implant immediate loading
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Universidade Federal de Goias
Dental Caries, Dental Cavities
Evaluation of Selective and Stepwise Excavation in Young Permanent Teeth With Deep Caries Lesions.
The purpose of this clinical trial is to evaluate and compare the outcomes of selective carious tissue removal versus stepwise carious tissue removal in young permanent teeth with deep carious lesions.
- Trial name
- SELECT (NCT06944028)
- Testing
- Selective excavation, Stepwise excavation
- Where
- Sweden
- Volunteers
- 666 people
- Sponsor
- Karolinska Institutet
Malocclusion, Orthodontic Appliance Complication
Microbiological and Epithelial Evaluation Related to the Use of Orthodontic Thermoplastic Device
Thermoplastic devices are used in orthodontic treatment and consists of a series of nearly invisible, removable aligners. However, every device used in the mouth can change the buccal flora and increase the number of bacterias.
- Trial name
- NCT02427763
- Testing
- hours of use (Essix), collect saliva, collect biofilm
- Where
- Brazil
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universidade Positivo
Dental Plaque, Gingivitis
Effectiveness of Toothbrushing Habits of Preschool Children, With or Without a Toothbrushing Assisting Application
The aim of this study is to investigate the effectiveness of the use of a toothbrushing assisting mobile application in dental plaque removal and adherence to the toothbrushing routine, in preschool children (3-5 yrs old) when…
- Trial name
- NCT05788692
- Testing
- electric tootbrush, manual toothbrush, toothbrushing assisting application
- Where
- 6 sites in Greece
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
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