Clinical trials: Tooth Disorder
Class III Malocclusion, Underbite
Effects of Class III Elastics on Stability of Orthopaedic Class III Correction
The purpose of this study is to evaluate the effects of adding elastics to orthodontic retainers on the stability of class III correction and whether it reduces the need for jaw surgery.
- Trial name
- NCT04911400
- Testing
- Upper-lower clear plastic retainers + Class III elastics, Upper-lower clear plastic retainers
- Where
- 2 sites in Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sydney Local Health District
Dental Pain, Dental Caries
Impact of Dental Pain on the Quality of Life
The aim of the present study was to evaluate the perceived impact of dental caries and dental pain on oral health-related quality of life (OHRQoL) among preschool children and their families.
- Trial name
- NCT02443207
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- Ana Flavia Granville-Garcia
MS (Multiple Sclerosis), Multiple Sclerosis (MS) - Relapsing-remitting
Comparison of Efficacy and Safety in Patients Switching From MabThera® to Rixathon® in Relapsing-Remitting Multiple Sclerosis
This observational study investigates if switching from MabThera® to Rixathon® is associated with changes in disease activity and/or safety in people with multiple sclerosis (MS).
- Conditions
- MS (Multiple Sclerosis), Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (Relapsing Remitting)
- Trial name
- NCT07235644
- Where
- Sweden
- Volunteers
- 184 people
- Sponsor
- Uppsala University
Malocclusion, Angle Class II
Predictors Associated With Seeking Orthodontic Treatment, Compliance and Treatment Success
Aim: to search for reasons for seeking orthodontic treatment, compliance during orthodontic treatment, drop-out from orthodontic treatment and success of orthodontic treatment.
- Trial name
- PONCOS (NCT03455634)
- Testing
- Twin Block, Sander bite jumping appliance
- Where
- Croatia
- Volunteers
- 110 people
- Sponsor
- Visnja Katic
Dental Caries
Fuji Type VII Sealant Versus Resin Based Sealant. A Clinical Trial
Purpose: To evaluate the retention and caries preventive effect of the glass-ionomer fissure sealants and resin-based fissure sealant.
- Trial name
- NCT02795728
- Testing
- Application of the GIC based sealant, Resin based sealant
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kamineni Institute of Dental Sciences
Dental Caries, Fissure Sealant
The Effect of an Adhesive System on the Retention and Caries Prevention for Fissure Sealants in Permanent Molars
Background: Resin-based fissure sealants (FS) are recommended to prevent pit-and-fissure caries development or prevent the progression of enamel caries lesion to frank cavitation into dentine.
- Trial name
- ResinFS (NCT06608563)
- Testing
- Fissure sealant without adhesive system (NO BOND), Fissure sealant with adhesive system (BOND)
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Laser, Intrusion
Histological Change of The Dentinal-Pulp Complex and Root Resorption
The purpose of the study is evaluate the histological changes of the dentinal-pulp complex and root resorption in maxillary premolars with intrusive orthodontic movement under a low power laser effects.
- Conditions
- Laser, Intrusion, Histology, Resorption
- Trial name
- NCT01642693
- Testing
- Low power laser in teeth after intrusive movement, Simulated laser in teeth with intrusive movements
- Where
- Colombia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Caries; Dentin, Fissure, Dental
Sealing of Occlusal Dentin Caries in Primary Molars.
BACKGROUND A simple method for arresting dentin caries with a tight seal of the cavity would exclude the need for injection and excavation, reduce the risk for dental fear and possibly postpone or eliminate the need for further…
- Conditions
- Caries; Dentin, Fissure, Dental, Dental Caries in Children, Glass Ionomer Cement
- Trial name
- SealCar (NCT05475145)
- Testing
- Resin based sealing [RBS]
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mats Bågesund
Dental Caries
Occlusal Bite Force Changes After Placement of Stainless Steel Crowns in Children
The aim of this study was to determine if restoring primary molars with SSCs would improve children's OBF.
- Trial name
- OBF (NCT03254069)
- Testing
- Stainless Steel Crowns
- Where
- Jordan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Permanent Molars, Dental Caries
Hall Technique vs Conventional Crown Restoration in Permanent Molars: Split-Mouth Trial in Children
The aim of this study is to compare the clinical and radiographic success of stainless steel crowns placed using the Hall Technique versus the conventional method in the restoration of permanent first molars in children, and to…
- Conditions
- Permanent Molars, Dental Caries, Tooth Decay, Permanent First Molar Caries
- Trial name
- HTCC-SM (NCT07186673)
- Testing
- Stainless steel crown placement using Hall Technique, Stainless steel crown placement using conventional method
- Where
- 2 sites in Syria
- Volunteers
- 10 people
- Sponsor
- Latakia University
Dental Plaque
Effects of Fixed and Removable Space Maintainers on Periodontal Health and DMFT/Dft Values
Space maintainers are appliances that applied when primary teeth were lost prematurely because of many reasons such as tooth decay, trauma, lack of germ of permanent tooth.4 Space problems play an important role in practice of…
- Trial name
- NCT03608345
- Testing
- space maintainer
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Dental Caries, Child Behavior
Fluoride vs Probiotic Toothpaste for Caries Prevention
This clinical trial had two objectives. The first was to compare the effectiveness of 950 ppm fluoride toothpaste versus probiotic toothpaste in preventing dental caries in 4- to 5-year-old children.
- Trial name
- NCT07579403
- Testing
- Fluoride toothpaste, Probiotic Toothpaste, Control Toothpaste
- Where
- China
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Symptomatic Apical Periodontitis
Comparison of Postoperative Pain After Double Antibiotic Paste vs Calcium Hydroxide in Teeth With Symptomatic Apical Periodontitis
This randomized controlled trial aims to compare the mean postoperative pain after using double antibiotic paste (DAP) versus calcium hydroxide (CH) as an intracanal medicament in teeth with symptomatic apical periodontitis.
- Trial name
- NCT07867951
- Testing
- Calcium Hydroxide (Ca(OH)2), Double Antibiotic Paste
- Where
- Pakistan
- Volunteers
- 662 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Endodontically Treated Teeth, Primary Teeth
Accuracy of Apex Locators in Primary Teeth
The aim of this study was to evaluate the effectiveness of tactile sense, digital periapical radiograph and two different varieties of electronic apex locators at working length determination in primary molars.
- Conditions
- Endodontically Treated Teeth, Primary Teeth, Pulp Necroses
- Trial name
- NCT04638972
- Testing
- working length determination techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
Collagen Degeneration
Type I Collagen Fragments in the GCF and Saliva During OTM
Investigate the levels of type I Collagen fragments ICTP and CTX in GCF and saliva during initial leveling and alignment of the teeth in a sample of adolescents undergoing orthodontic treatment.
- Trial name
- NCT05020431
- Testing
- Biological measuring of collagen fragments biomarker during orthodontic tooth movement
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pulpitis, Pulpotomy
Clinical and Radiographic Evaluation of Laser Photobiomodulation Pulpotomy of Primary Molars in Children
This study aimed to evaluate the clinical and radiographic outcomes of photobiomodulation pulpotomy compared to MTA pulpotomy in primary molars in children.
- Trial name
- NCT05850780
- Testing
- Photobiomodulation, MTA
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Aliaa Hamouda
Molar Incisor Hypomineralisation
Correlation Between Colour and Hypersensitivity of First Permanent Molars With Molar Incisor Hypomineralisation (MIH)
Cheese molars (MIH: molar incisor hypomineralisation) can be recognized not only by their colour abnormalities but also by their hypersensitivity.
- Trial name
- NCT07727044
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Basel
Endodontic Disease
Outcome of Regenerative Endodontic Procedures
Clinical management of immature non-vital (necrotic) permanent teeth is challenging, due to inherent structural weakness. Earlier management of such teeth relied on the traditional calcium hydroxide (Ca(OH)2) apexification…
- Trial name
- NCT05612451
- Testing
- Regenerative Endodontic Procedures, non-setting calcium hydroxide, modified triple antibiotic paste
- Where
- Jordan
- Volunteers
- 45 people
- Sponsor
- King Abdullah University Hospital
Dental Anxiety, Dental Phobia
Virtual Reality Distraction for Dental Anxiety (PILOT)
Introduction. Dental fear and anxiety (DFA) is a condition that affects approximately a quarter of children and adolescents. Lack of patient cooperation due to DFA can create an environment of stress, often obligating dentists to…
- Conditions
- Dental Anxiety, Dental Phobia, Dental Trauma, Dental Diseases
- Trial name
- NCT05898100
- Testing
- Virtual Reality Distraction, Dental Clinic's Standard Treatment
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- St. Justine's Hospital
Pain
Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain
Evaluation of the efficacy and safety of a single dose of an ibuprofen effervescent tablet in the treatment of pain following third molar extraction in comparison to single doses of placebo, standard ibuprofen tablets, and…
- Trial name
- NCT00631111
- Testing
- effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
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